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Showing "Goldman Sachs" PubMed Articles, all 20

Understanding the Hill-Sachs Lesion in Its Role in Patients with Recurrent Anterior Shoulder Instability.

The purpose of this study is to provide an update to the orthopedic field in regard to treatment of the Hill-Sachs lesion and anterior shoulder instability. The review highlights the most current knowledge of epidemiology, clinical evaluation, and surgical methods used to treat Hill-Sachs lesions. It also details the relevant clinical and surgical findings that have been made throughout the literature in the past couple of years.

Glenohumeral Dislocation With Engaging Hill-Sachs Lesion.

A 20-year-old military cadet injured his left shoulder after landing in an abducted and externally rotated arm position while participating in a mandatory obstacle course. Following examination, the individual was taken to the emergency department, where radiographs confirmed an anterior dislocation of the glenohumeral joint and a large Hill-Sachs lesion wedged on the glenoid. Results of noncontrast magnetic resonance imaging and a computed tomography scan confirmed the presence of a large Hill-Sachs lesion...

Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation-Second Edition.

Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of Articulation-Second Edition (GFTA-2) to identify candidates for a screening measure of speech sound production skills.

Rafting technique without bone grafting in reverse Hill-Sachs lesions.

In this article, we report a case of bilateral posterior shoulder instability, having reverse Hill-Sachs lesions of 25 to 50% of the articular surface on the right side, and of 50% on the left side. The defects were anatomically reconstructed after tuberculum minus osteotomy by elevation of the articular surface and buttressing with raft screws without graft usage. Early rehabilitation with pendulum shoulder exercises was started at third postoperative day. At postoperative sixth week, patient had full rang...

Partial Resurfacing for Humeral Head Defects Associated With Recurrent Shoulder Instability.

Recurrent traumatic shoulder instability is a complex clinical entity that commonly affects young, active patients. Humeral head defects are frequently associated with this condition, but specific treatment to stabilize the shoulder is rarely needed. Management options for defects of the humeral head that do necessitate treatment carry various risks and disadvantages, including the need for bone or soft tissue healing, complications related to hardware, and loss of motion. Partial prosthetic resurfacing has...

Distinct progression patterns of brain disease in infantile and juvenile gangliosidoses: Volumetric quantitative MRI study.

GM1-gangliosidosis and GM2-gangliosidosis (Tay-Sachs disease and Sandhoff disease) are unrelenting heritable neurodegenerative conditions of lysosomal ganglioside accumulation. Although progressive brain atrophy is characteristic, longitudinal quantification of specific brain structures has not been systematically studied.

Clinical Outcome of Arthroscopic Remplissage as Augmentation During Arthroscopic Bankart Repair for Recurrent Anterior Shoulder Instability.

We aimed to assess functional outcomes and postoperative recurrence rate associated with the remplissage procedure used for bone augmentation with Bankart repair in patients with Hill-Sachs lesions after shoulder dislocation.

Organoid Models of Cancer Explode with Possibilities.

Organoids have tremendous promise for modeling human cancers and revealing new biological insights. Sachs et al. (2018), Seino et al. (2018) (in this issue of Cell Stem Cell), and Broutier et al. (2017) derive cancer organoids from breast, pancreas, and liver, respectively, not only reporting new methodologies but also showing their utility for translational and clinical cancer research.

Managing Bony Defects of the Shoulder Joint that Occur in Association with Dislocation.

Defects to the articular surface of the humeral head have been known to be associated with shoulder dislocation since the 19th century. It wasn't until 1934 that the first description of the ubiquitous compression fracture of the posterolateral humeral head that occurs with traumatic anterior instability appeared. From 1940, this defect became referred to as a Hill-Sachs lesion after the investigators who reported the condition. The significance of, and therefore treatment of, these and other such bony defe...

COMPARATIVE STUDY on the MANAGEMENT of GLENOHUMERAL JOINT DISLOCATION. Closed Reduction vs. Arthroscopic Remplissage with Bankart Lesion Repair.

Conservative treatment of posttraumatic anteroinferior shoulder instability leads to a high failure rate and consequently high recurrence in young and active population. Each recurrence can increase the structural damage of both bony structures and soft tissues (Hill-Sachs lesion, Bankart lesion). Remplissage technique combined with Bankart repair have been proposed as a treatment option.

Recent advances in the genomics and therapy of BCR/ABL1-positive and -negative chronic myeloproliferative neoplasms.

This review is based on the presentations and deliberations at the 7th John Goldman Chronic Myeloid Leukemia (CML) and Myeloproliferative Neoplasms (MPN) Colloquium which took place in Estoril, Portugal on the 15th October 2017, and the 11th post-ASH International Workshop on CML and MPN which took place on the 6th-7th December 2016, immediately after the 58th American Society of Hematology Annual Meeting. Rather than present a resume of the proceedings, we have elected to address some of the topical transl...

Acrochordons on the neck; a remarkable clinical feature of tuberous sclerosis showing different patterns.

Sachs and Lipsker(1) recently published a few patients diagnosed with tuberous sclerosis (TS) presenting with multiple loosely arranged acrochordons (molluscum pendulum) located on the posterior neck showing a lace-like distribution and they proposed the term "molluscum pendulum necklace sign" for these typically located lesions. They detected acrochordons in five cases (17%) in a retrospectively analysed consecutive series of 29 TS patients, of whom four (three adults and one child) remarkably showed this ...

Surface proximity effect in sedimentation investigated by digital holographic microscopy.

In this paper, we measure the proximity effect of a flat wall on the sedimentation of colloidal particles by the use of digital holographic microscopy (DHM). DHM provides quantitative phase contrast and three-dimensional (3D) imaging in arbitrary time scales that are suitable to investigate various phenomena, including dynamic behavior of colloids. 3D information is obtained by post-processing of the recorded digital holograms through the angular spectrum propagation approach for numerical reconstruction. W...

Posterior Shoulder Instability.

Posterior shoulder instability is a relatively uncommon condition, occurring in ∼10% of those with shoulder instability. Because of the rarity of the condition and the lack of knowledge in treatment, it is often misdiagnosed or patients experience a delay in diagnosis. Posterior instability typically affects athletes participating in contact or overhead sports and is usually the result of repetitive microtrauma or blunt force with the shoulder in the provocative position of flexion, adduction, and interna...

Eponymous terms in anterior shoulder stabilization surgery.

Shoulder dislocation and its treatment is probably as old as time. Surgical treatment has gained acceptance recently, especially in recurrent cases. Within roughly the last 100 years numerous treatment strategies have been developed and questions elucidated regarding the entity of shoulder instability.Shoulder instability holds many eponymous terms. By means of literature and historical research we present the biographical background of some common eponymous terms and the original publication on which those...

Enzymatic properties of β-N-acetylglucosaminidases.

β-N-Acetylglucosaminidases (GlcNAcases) hydrolyse N-acetylglucosamine-containing oligosaccharides and proteins. These enzymes produce N-acetylglucosamine (GlcNAc) and have a wide range of promising applications in the food, energy, and pharmaceutical industries, such as synergistic degradation of chitin with endo-chitinases and using GlcNAc to produce sialic acid, bioethanol, single-cell proteins, and pharmaceutical therapeutics. GlcNAcases also play an important role in the dynamic balance of cellular O-l...

Magnetic behavior of metastable Fe films grown on Ir(111).

We investigated the growth of ultra-thin Fe films on Ir(111) by means of <i>in-situ</i> low energy electron diffraction and spin-resolved photoemission techniques. We observe a (1x1) diffraction pattern, characteristic of the <i>fcc</i> substrate, below 4 monolayers (ML). Then, a complex superstructure starts to develop, compatible with the formation of <i>bcc</i>-like Fe domains aligned with the substrate according to the Kourdjumov-Sachs orientation relationships. The a...

Estimating outflow facility through pressure dependent pathways of the human eye.

We develop and test a new theory for pressure dependent outflow from the eye. The theory comprises three main parameters: (i) a constant hydraulic conductivity, (ii) an exponential decay constant and (iii) a no-flow intraocular pressure, from which the total pressure dependent outflow, average outflow facilities and local outflow facilities for the whole eye may be evaluated. We use a new notation to specify precisely the meaning of model parameters and so model outputs. Drawing on a range of published data...

Effects of thermal and deformation on martensitic transformation and magnetic properties in Fe-17%Mn-4.5%X (X=Co and Mo) alloys.

In this study, the Co and Mo addition to Fe-Mn based alloys was investigated to observe its effect on martensitic phase transformation. Two types of martensite structure occurred from the surface observations made by SEM for Co-added and Mo-added alloys morphologically in austenite grain. With the help of TEM studies, it was understood that these martensite structures are ε (h.c.p.) and α' (b.c.c.). TEM investigations showed that the orientation relationship between γ (f.c.c.) and ε phases corresponds t...

Zero Echo Time Imaging of the Shoulder: Enhanced Osseous Detail by Using MR Imaging.

Purpose To determine the intermodality agreement of morphologic grading and clinically relevant quantitative measurements between computed tomography (CT) and zero echo time (ZTE) magnetic resonance (MR) imaging of the shoulder. The primary objective was to demonstrate the clinical applicability of ZTE in osseous shoulder imaging. Materials and Methods Thirty-four patients undergoing standard-of-care (SOC) MR imaging with concomitant CT were enrolled in this institutional review board-approved study. ZTE im...

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