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Showing "HORIZON PHARMACETICALS CORPORATION" PubMed Articles 1–25 of 121

Plasmonic Horizon in Gold Nanosponges.

An electromagnetic wave impinging on a gold nanosponge coherently excites many electromagnetic hot-spots inside the nanosponge, yielding a polarization dependent scattering spectrum. In contrast, a hole, recombining with an electron, can locally excite plasmonic hot-spots only within a horizon given by the lifetime of localized plasmons and the speed carrying the information that a plasmon has been created. This horizon is about 57 nm, decreasing with increasing size of the nanosponge. Consequently, photolu...

Black Hole Entropy from Bondi-Metzner-Sachs Symmetry at the Horizon.

Near the horizon, the obvious symmetries of a black hole spacetime-the horizon-preserving diffeomorphisms-are enhanced to a larger symmetry group with a three-dimensional Bondi-Metzner-Sachs algebra. Using dimensional reduction and covariant phase space techniques, I investigate this augmented symmetry and show that it is strong enough to determine the black hole entropy in any dimension.

Exposure to oil spill chemicals and lung function in Deepwater Horizon disaster response workers.

To assess the relationship between total hydrocarbon (THc) exposures attributed to oil spill clean-up work and lung function 1-3 years after the Deepwater Horizon (DWH) disaster.

The deepwater horizon oil spill coast guard cohort study: A cross-sectional study of acute respiratory health symptoms.

Over 8500 United States Coast Guard (USCG) personnel were deployed in response to the Deepwater Horizon (DWH) oil spill; however, human respiratory effects as a result of spill-related exposures are relatively unknown.

Soil attributes drive nest-site selection by the campo miner Geositta poeciloptera.

Substrate type is a key-factor in nest-site selection and nest architecture of burrowing birds. However, little is known about which factors drive nest-site selection for these species, especially in the tropics. We studied the influence of soil attributes on nest-site selection by the campo miner Geositta poeciloptera, an open grassland bird that builds its nests within soil cavities. For all nests found, we measured the depth of the nest cavity and the resistance of the soil to penetration, and identified...

Lung function in oil spill response workers 1-3 years after the Deepwater Horizon disaster.

Little is known about the effects of inhalation exposures on lung function among workers involved in the mitigation of oil spills. Our objective was to determine the relationship between oil spill response work and lung function 1-3 years after the Deepwater Horizon (DWH) disaster.

The c-index is not proper for the evaluation of $t$-year predicted risks.

We show that the widely used concordance index for time to event outcome is not proper when interest is in predicting a $t$-year risk of an event, for example 10-year mortality. In the situation with a fixed prediction horizon, the concordance index can be higher for a misspecified model than for a correctly specified model. Impropriety happens because the concordance index assesses the order of the event times and not the order of the event status at the prediction horizon. The time-dependent area under th...

Amazon's cloud on the healthcare horizon.

Is hope on the horizon for premature ovarian insufficiency?

Growth: A Journey from Experience to Higher Perception Among Iranian Muslim CPR Survivors.

Several studies have been conducted among cardiopulmonary resuscitation (CPR) survivors. Some studies have shown that positive and negative experiences coexist. Emotional distress and psychopathology in CPR survivors are related to the urgent need to make growth. Understanding the meaning of CPR survivors' lived experiences of growth may facilitate their growth. The aim of the study was to illuminate the meaning of CPR survivor's lived experiences of growth in southeast Iran. A qualitative design using a ph...

Geosphere-biosphere circulation of chemical elements in soil and plant systems from a 100 km transect from southern central Norway.

Geochemical element separation is studied in 14 different sample media collected at 41 sites along an approximately 100-km long transect north of Oslo. At each site, soil C and O horizons and 12 plant materials (birch/spruce/cowberry/blueberry leaves/needles and twigs, horsetail, braken fern, pine bark and terrestrial moss) were sampled. The observed concentrations of 29 elements (K, Ca, P, Mg, Mn, S, Fe, Zn, Na, B, Cu, Mo, Co, Al, Ba, Rb, Sr, Ti, Ni, Pb, Cs, Cd, Ce, Sn, La, Tl, Y, Hg, Ag) were used to inve...

NewsCAP: On the horizon: a blood test for identifying solid organ tumors and their origin.

Evaluation of NO emissions of a retrofitted Euro 5 passenger car for the Horizon prize "Engine retrofit".

The Horizon 2020 prize for the "Engine Retrofit for Clean Air" aims at reducing the pollution in cities by spurring the development of retrofit technology for diesel engines. A Euro 5 passenger car was retrofitted with an under-floor SCR (Selective Catalytic Reduction) for NO catalyst in combination with a solid ammonia based dosing system as the NO reductant. The vehicle was tested both on the road and on the chassis dynamometer under various test cycles and ambient temperatures. The NO emissions were redu...

Soft-Hair-Enhanced Entanglement Beyond Page Curves in a Black Hole Evaporation Qubit Model.

We propose a model with multiple qubits that reproduces the thermal properties of four-dimensional Schwarzschild black holes (BHs) by simultaneously taking account of the emission of Hawking particles and the zero-energy soft-hair evaporation at the horizon. The results verify that the entanglement entropy between a qubit and other subsystems, including emitted radiation, is much larger than the BH entropy analogue of the qubit, as opposed to the Page curve prediction. Our result suggests that early Hawking...

Determination of Early Immune Function in Sepsis and Its Influence on Organ Dysfunction - Is a More Pragmatic Outcome on the Horizon?

Cleanup in the Gulf: Oil Spill Dispersants and Health Symptoms in Deepwater Horizon Responders.

Degradation of Deepwater Horizon oil buried in a Florida beach influenced by tidal pumping.

After Deepwater Horizon oil reached the Florida coast, oil was buried in Pensacola Beach (PB) sands to ~70cm depth, resulting in Total Petroleum Hydrocarbon (TPH) concentrations up to ~2kg per meter of beach. This study followed the decomposition of the buried oil and the factors influencing its degradation. The abundance of bacteria in oiled sand increased by 2 orders of magnitude within one week after oil burial, while diversity decreased by ~50%. Half-lives of aliphatic and aromatic hydrocarbons reached ...

Receding horizon H∞ guaranteed cost tracking control for microwave heating medium with temperature-dependent permittivity.

This paper considers the temperature spectrum tracking control of microwave heating model, in the presence of asymmetrical input saturation, nonhomogeneous Neumann boundary condition and temperature-dependent permittivity. The sufficient condition for the existence of receding horizon H∞ guaranteed cost control is proposed based on the derived finite-dimensional ordinary differential equation (ODE) error model. Furthermore, by on-line updating and solving linear matrix inequalities (LMIs) optimization pro...

Combined effects of hypoxia or elevated temperature and Deepwater Horizon crude oil exposure on juvenile mahi-mahi swimming performance.

This study examined potential interactive effects of co-exposure to Deepwater Horizon (DWH) crude oil (∼30 μg L ΣPAHs) for 24 h and either hypoxia (2.5 mg O L; 40% O saturation) or elevated temperature (30 °C) on the swimming performance of juvenile mahi-mahi (Coryphaena hippurus). Additionally, effects of shorter duration exposures to equal or higher doses of oil alone either prior to swimming or during the actual swim trial itself were examined. Only exposure to hypoxia alone or combined wi...

Strontium isotopes reveal weathering processes in lateritic covers in southern China with implications for paleogeographic reconstructions.

The isotope ratios of Sr are useful tracers for studying parent material sources, weathering processes, and biogeochemical cycling. Mineralogical and geochemical investigations of two lateritic weathering covers, in an area close to the Tropic of Cancer (Guangxi Province, southern China), were undertaken to study the regional weathering processes and Sr isotopic sources. We found that weathering and decomposition of Rb- and Sr-bearing minerals change the Sr isotopic composition in weathering products (later...

On Building Online Visualization Maps for News Data Streams by Means of Mathematical Optimization.

In this article we develop a novel online framework to visualize news data over a time horizon. First, we perform a Natural Language Processing analysis, wherein the words are extracted, and their attributes, namely the importance and the relatedness, are calculated. Second, we present a Mathematical Optimization model for the visualization problem and a numerical optimization approach. The model represents the words using circles, the time-varying area of which displays the importance of the words in each ...

Identifying oil/marine snow associations in mesocosm simulations of the Deepwater Horizon oil spill event using solid-state 13C NMR spectroscopy.

The Deepwater Horizon oil spill stimulated the release of marine snow made up of dead/living plankton/bacteria and their exopolymeric polysaccharide substances (EPS), termed marine oil snow (MOS), promoting rapid removal of oil from the water column into sediments near the well site. Mesocosm simulations showed that Macondo surrogate oil readily associates with the marine snow. Quantitative solid-state 13C NMR readily distinguishes this oil from naturally formed marine snow and reveals that adding the dispe...

Dynamical Formation of Kerr Black Holes with Synchronized Hair: An Analytic Model.

East and Pretorius have successfully evolved, using fully nonlinear numerical simulations, the superradiant instability of the Kerr black hole (BH) triggered by a massive, complex vector field. Evolutions terminate in stationary states of a vector field condensate synchronized with a rotating BH horizon. We show that these end points are fundamental states of Kerr BHs with synchronized Proca hair. Motivated by the "experimental data" from these simulations, we suggest a universal (i.e., field-spin independe...

Changes on the Horizon for Drug Repurposing, Rescue, and Repositioning at ASSAY.

Sources and fate of polycyclic aromatic compounds (PAHs, oxygenated PAHs and azaarenes) in forest soil profiles opposite of an aluminium plant.

Little is known about oxygenated polycyclic aromatic hydrocarbons (OPAHs) and azaarenes (AZAs) in forest soils. We sampled all horizons of forest soils from five locations at increasing distances from an Al plant in Slovakia, and determined their polycyclic aromatic compound (PACs) concentrations. The ∑29PAHs concentrations were highest in the Oa and lowest in the Oi horizon, while the ∑14OPAHs and ∑4AZAs concentrations did not show a consistent vertical distribution among the organic horizons. The co...

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