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PubMed Journals Articles About "Hansoh Pharma Shares Head Skyward After HKEX Debut" RSS

18:47 EDT 19th July 2019 | BioPortfolio

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Showing "Hansoh Pharma shares head skyward after HKEX debut" PubMed Articles 1–25 of 2,600+

Sex and Education: Does Sexual Debut During Adolescence Lead to Poor Grades?

Because many U.S. teenagers experience their first sexual intercourse during high school, understanding whether sexual behavior and academic performance are related is important. However, research on sexual debut and grades has produced inconsistent findings.


Data science tools and applications on the way to Pharma 4.0.

Multiple obstacles are driving the digital transformation of the biopharmaceutical industry. Novel digital techniques, often marketed as 'Pharma 4.0', are thought to solve some long-existing obstacles in the biopharma life cycle. Pharma 4.0 concepts, such as cyberphysical systems and dark factories, require data science tools as technological core components. Here, we review current data science applications at various stages of the bioprocess life cycle, including their scopes and data sources. We are conv...

The Complexity of Compliance in Sample Management: A Review of Key Issues Impacting Small-Molecule and Biological Sample Management in Early Drug Discovery.

The discovery of new medicines has become increasingly more challenging and requires significant collaboration between pharma, biotech, academia, and technology to be successful. These partnerships necessitate the streamlined exchange of samples while adhering to the increasingly complex set of legal and proprietary restrictions, government legislation, and ethical considerations associated with samples. There is a significant volume of literature published on clinical sample compliance but little describin...


Physicians in the pharmaceutical industry: their roles, motivations, and perspectives.

Although physicians occupy a significant number of key positions in the pharmaceutical industry, practicing clinicians are often unaware of the variety of career paths within this industry, or of the structure of a pharmaceutical company. Here, we address questions that practicing clinicians frequently ask their colleagues in the pharmaceutical industry. In addition to providing an overview of the common roles occupied by physicians in pharma, we also describe the various motivations for transitioning into ...

Establishing and Maintaining a Robust Sample Management System.

This paper has been written by the SLAS Sample Management Special Interest Group to serve as a guide to the best practices and methods in establishing and maintaining a high-quality sample management system. The topics covered are applicable to sample types ranging from small molecules to biologics to tissue samples. It has been put together using the collective experience of the authors in start-up companies, small pharma, agricultural research, IT, academia, biorepositories, and large pharma companies. Ou...

PSORIATIC ARTHRITIS IN CHILDREN: CHARACTERISTICS OF THE CLINICAL PICTURE.

The aim of the study is to establish the features of the clinical course of psoriatic arthritis in children. 83 patients with psoriatic arthritis (PSA) were examined. The terms of formation of articular and skin syndromes in PSA in children, as well as options for the onset and height of the disease and features of the course in childhood were revealed. Based on the results of the study, it should be concluded that, in contrast to the literature data, the majority of patients with PSA disease debut falls on...

Radial Head Replacement Through a Kocher Approach.

Radial head fractures are some of the most common elbow fractures. Fractures with 3 or more fracture fragments have been shown to have worse outcomes when treated with open reduction and internal fixation (ORIF). Radial head replacement offers an alternative treatment for those more comminuted radial head fractures.

Potential effects of increased openness in pharma: the original knowledge behind new drugs.

This study seeks to determine potential changes in the degree of openness in pharmaceutical R&D by investigating where the knowledge behind new molecular entities (NMEs) comes from in terms of type of organization, geography and time. We find that the organizations granted NMEs increasingly rely on external knowledge sources but that these are increasingly shared among NME grantees. Universities are the most important indirect knowledge contributor and their relative importance has increased with time. NME ...

A new perspective on the head direction cell system and spatial behavior.

The head direction cell system is an interconnected set of brain structures containing neurons whose firing is directionally tuned. The robust representation of allocentric direction by head direction cells suggests that they provide a neural compass for the animal. However, evidence linking head direction cells and spatial behavior has been mixed. Whereas damage to the hippocampus yields profound deficits in a range of spatial tasks, lesions to the head direction cell system often yield milder impairments ...

Head first - Review of epilepsy head injury risk and protection.

The causes of falls and resultant head injuries in people with epilepsy are complex and represent important clinical issues significantly impacting on safety, quality of life and long-term prognosis. A general solution for many years has been to provide helmets for head protection. There is poor understanding of the influencing risk factors and solutions to give person-centred clinical advice.

Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer.

Recommendations for perioperative therapy in head and neck cancer are not explicit and recurrence occurs frequently. Circulating tumor DNA is an emerging cancer biomarker, but has not been extensively explored for detection of recurrence in head and neck cancer.

IMRT-based treatment of unknown primary malignancy of the head and neck: Outcomes and improved toxicity with decreased mucosal dose and larynx sparing.

Radiation therapy for squamous cell cancer of the head and neck with unknown primary (head and neck CUP) has been associated with significant levels of swallowing toxicity. We examined the effect of changes in mucosal dose on development of laryngeal strictures and percutaneous endoscopic gastrostomy (PEG) dependence.

Assessment of Gender Differences in Perceptions of Work-Life Integration Among Head and Neck Surgeons.

The factors that contribute to gender discrepancies among attending head and neck surgeons have yet to be fully characterized.

Outcomes and cost implications of microvascular reconstructions of the head and neck.

Critical review of current head and neck reconstructive practices as related to free flap donor sites and their impact on clinical outcomes and cost.

Assessing functional outcomes in head and neck surgical oncology.

A reliable method of measuring functional outcomes is essential to inform treatment decisions in head and neck cancer.

Prophylactic human papilloma virus vaccination in head and neck: indications and future perspectives.

To gain the evidence-based knowledge concerning the efficacy of HPV vaccination for oropharyngeal sites and to highlight the trials and strategies for vaccine administration in HPV-dependent head and neck diseases.

When Have We Done Enough? Provider-Patient Discord in Terminal Head and Neck Cancer.

An alignment maximization method for the kinematics of the eye and eye-head fixations.

The orientation of human eyes is uniquely defined with respect to their gaze direction, known as Donders' law. Further, the manner in which the eyes follow Donders' law varies as a function of the situation. When the head is stationary, the Donders' surfaces are flat planes but they tilt when eye fixation distance changes. These planes also shift and rotate when head orientation changes with respect to the direction of gravito-inertial acceleration. When the head is free to rotate, the Donders' surfaces are...

Using the Motion of the Head-Neck as a Joystick for Orientation Control.

Head-neck interfaces have the potential to command and control orientation tasks when the hand-wrist is not available for use as a joystick. We pose the question in this paper - How well can the head-neck be used to perform orientation tasks when compared to the hand-wrist? Anatomically, the motion of the head-neck is similar to that of the hand-wrist. We hypothesize that the head-neck motion can be as effective as the motion of the hand-wrist to control orientation tasks. A study was designed to characteri...

Cyber-Physical-based PAT (CPbPAT) framework for Pharma 4.0.

Industry 4.0 aims to integrate manufacturing operations into a seamless digital whole by incorporatingflexibility, agility, re-configurability, and sustainability. The result of this integration is a "smart factory" that is more lean, agile, and flexible in operations. There are valid reasons, and perhaps requirements, for pharmaceutical industries to embrace smart factory and to ''borrow'' the concept of Industry 4.0 to give rise to ''Pharma 4.0'' (i.e., the pharmaceutical version of Industry 4.0). This pa...

Outcomes of dental and craniofacial osseointegrated implantation in head and neck cancer patients.

Treatment of head and neck cancer may result in disfiguring and debilitating anatomical changes. Osseointegrated implants may be used in these patients to facilitate attachment of implant-retained dentures or cosmetic prostheses.

Expression of CD44, EGFR, p16, and their mutual combinations in patients with head and neck cancer: Impact on outcomes of intensity-modulated radiation therapy.

Progress in radiation treatment of head and neck squamous cell carcinoma (HNSCC) deserves the studies focused on molecular predictors that would help to enhance individually tailored treatment.

Profile of Head Injuries: Pre hospital Care, Diagnosis and Severity in an Ethiopian Tertiary Hospital.

Consistent data on head injury is lacking especially in the low and middle income countries. Our study tries to characterize head injury patients at the emergency room of one of the few tertiary public hospitals giving neurosurgical care in the country.

Design and testing of a 24-channel head coil for MR imaging at 3 T.

To offer the new head coil option (with a lower channel count) of an RF coil array that provides comparable performance to the commercial 32-channel head coil.

The Effect of Bimaxillary Surgery on the Airway Morphology in Class III Patients: Taking Into Account the Head Posture During Walking.

To assess changes in head and neck posture, airway, hyoid, tongue, and soft palate in skeletal class III individuals whose cephalograms were taken using dynamic natural head positioning method with an inclinometer.


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