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PubMed Journals Articles About "HotSpot Emerges From Stealth Mode Closes 45mm Series" RSS

13:34 EDT 24th March 2019 | BioPortfolio

HotSpot Emerges From Stealth Mode Closes 45mm Series PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest HotSpot Emerges From Stealth Mode Closes 45mm Series articles that have been published worldwide.

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Showing "HotSpot emerges from stealth mode closes 45mm Series" PubMed Articles 1–25 of 6,800+

Comparison of Knowledge, Attitude, and Practice among Communities Living in Hotspot and Non-Hotspot Areas of Dengue in Selangor, Malaysia.

Dengue has affected more than one-third of the world population and Malaysia has recorded an increase in the number of dengue cases since 2012. Selangor state recorded the highest number of dengue cases in Malaysia. Most of the dengue infections occur among people living in hotspot areas of dengue. This study aims to compare Knowledge, Attitude, and Practice among communities living in hotspot and non-hotspot dengue areas.


Evaluation of direct and alternating current on nitrate removal using a continuous electrocoagulation process: Economical and environmental approaches through RSM.

This study aims to investigate the effects of alternating current (AC) and direct current (DC) for nitrate removal and its operating costs by using a continuous electrocoagulation (CEC) process. For this purpose, two series of 31 experiments, which were designed by response surface method (RSM), were carried out in both cases of the AC and the DC modes. In each series, the effect of selected parameters, namely, initial nitrate concentration, inlet flow rate, current density and initial pH along with their i...

On-chip silicon mode blocking filter employing subwavelength-grating based contra-directional coupler.

Mode blocking may be required in mode-division multiplexing (MDM) systems. We demonstrate a silicon mode blocking filter using a subwavelength grating-based contra-directional coupler. The device is capable of blocking the undesired mode channel without affecting the propagation of the other modes. As a proof-of-concept experiment, two mode blocking filters are experimentally demonstrated, which can block the TE mode and the TE mode, respectively. Low crosstalk (≤21.0 dB) and reasonable insertion losses (...


Beyond reasonable drought: hotspots reveal a link between the 'Big Dry' and cryptosporidiosis in Australia's Murray Darling Basin.

There is little evidence on how the health impacts of drought vary spatially and temporally. With a focus on waterborne cryptosporidiosis, we identify spatio-temporal hotspots and by using interrupted time series analysis, examine the impact of Australia's Big Dry (2001-2009) in these disease clusters in the Murray Darling Drainage Basin. Analyses revealed a statistically significant hotspot in the north of the Australian Capital Territory (ACT) and a hotspot in the north-eastern end of the basin in Queensl...

Searching for longevity hotspots in Denmark.

While existing research on regions with high prevalence of centenarians has focused on selected candidate geographical regions, we explore the existence of hotspots in the whole of Denmark.We performed a Kulldorff spatial scan, searching for regions of birth, and of residence at age 71, where an increased percentage of the cohort born 1906-1915 became centenarians. We then compared mortality hazards for these regions to the rest of the country.We found a birth hotspot of 222 centenarians, 1.37 times more th...

Assessing subcutaneous adipose tissue by simple and portable field instruments: Skinfolds versus A-mode ultrasound measurements.

This study compared subcutaneous adipose tissue (SAT) measurements using a skinfold caliper and Renco Lean-Meater Series 12 A-mode portable ultrasound scanner (A-US). It aimed to assess their inter- and intra-rater reliability and measure the agreement between both methods.

Bridged-bowtie and cross bridged-bowtie nanohole arrays as SERS substrates with hotspot tunability and multi-wavelength SERS response.

In this paper, we present bridged-bowtie nanohole arrays and cross bridged-bowtie nanohole arrays in a gold thin film as surface enhanced Raman scattering (SERS) substrates. These SERS substrates not only exhibit large electromagnetic enhancement of SERS but also have the SERS enhancement spread over a much larger area than what could be present in SERS substrates consisting of nanopillar arrays or nanopillar plasmonic nanoantennas. Numerical simulations based on the finite difference time domain (FDTD) met...

MALAT1: a potential biomarker in cancer.

The research of long non-coding RNAs (lncRNAs) has become a new passion with the discovery of abundant new lncRNAs and extensive investigation of their roles in various diseases, especially in cancers. Metastasis associated in lung adenocarcinoma transcript 1 (MALAT1) emerges as a hotspot, which has been reported to be involved in dysregulation of cell signaling and closely correlated with cancer development, progression, and response to therapy. This review is a brief update of the current knowledge relate...

Traveling pulse emerges from coupled intermittent walks: A case study in sheep.

Monitoring small groups of sheep in spontaneous evolution in the field, we decipher behavioural rules that sheep follow at the individual scale in order to sustain collective motion. Individuals alternate grazing mode at null speed and moving mode at walking speed, so cohesive motion stems from synchronising when they decide to switch between the two modes. We propose a model for the individual decision making process, based on switching rates between stopped / walking states that depend on behind / ahead l...

The Transcription and Expression Profile of p53 Mutant Reveals New Aspects of Gain-of-Function for Mutant p53.

Missense mutations in the p53 coding gene cause loss- and gain-of-function. We have identified a hotspot mutation, p53 , that results in aggressive progression of tumorigenesis in a knock-in mouse model. To understand the biological significance of the p53 mutation, we performed ChIP-on-chip combined with microarray assay to profile the regulated gene expression pattern. We could classify the p53 mutant function into six categories. Among these, we reveal a new aspect of gain-of-function, the enhancement of...

Getting at Mode Share: Comparing 3 Methods of Travel Mode Measurement for School Travel Research.

Mode share is an important metric for active school travel programs. Common methods for measuring mode share include Hands Up surveys and family surveys, but these require teacher and parental involvement. We used these methods as part of an evaluation of a school-based bicycle training program, and added a novel observational count approach. This paper compares mode share results across the 3 methods.

Direct Detection of DNA Using 3D Surface Enhanced Raman Scattering Hotspot Matrix.

Silver nanoparticles (AgNPs) are evaporatively self-assembled into the 3D surface enhanced Raman scattering (SERS) hotspot matrix with the assistant of glycerol to improve the spectral reproducibility in direct DNA detection. AgNPs and DNA in the glycerol-stabilized 3D SERS hotspot matrix are found to form flexible sandwich structures through electrostatic interaction where neighboring AgNPs create uniform and homogeneous localized surface plasmon resonance (LSPR) coupling environments for central DNA. Near...

Transverse mode-switchable fiber laser based on a photonic lantern.

We propose and experimentally demonstrate an intra-cavity transverse mode-switchable fiber laser based on a mode-selective photonic lantern and a few-mode Er-doped fiber amplifier. The six lowest-order LP modes can lase independently and are switchable by changing the input port of the photonic lantern. We measured the slope efficiency, mode intensity profile, and optical spectrum of each lasing mode. In addition, we demonstrate donut-shaped LP and LP modes using incoherent superposition and simultaneous la...

A stealth emulsion based on natural rubber latex, core-shell ferrofluid/carbon black in the S and X -band.

A lossy dielectric with appropriate magnetic property is one of the requirements of a stealth material. The thickness of the absorber and the corresponding bandwidth of absorption are also other deciding factors which determine the choice of the material for microwave absorbers. A stable emulsion, which is lossy as well as magnetic, is promising, since it can be coated on surfaces with required thickness in the desired band. A magnetic nanofluidic emulsion serves the purpose. A microwave absorbing emulsion ...

Fully-differential Piezoelectric Button-like Mode Disk Resonator for Liquid Phase Sensing.

We present a unique lateral shear resonance mode excited in a micro-electro-mechanical (MEM) disk resonator. We refer to this proposed mode as the Button-like (BL) mode. The BL mode has a characteristic lateral strain profile (based on the sum of orthogonal strain components in the plane of fabrication) resembles a shirt button. Hence our choice of name for this mode. The strain profile of the BL mode is highly suited for piezoelectric transduction. Like the more widely reported Wine Glass (WG) or elliptica...

Genetic screen in a large series of patients with primary progressive aphasia.

Primary progressive aphasia (PPA) is a neurological syndrome, associated with both frontotemporal dementia and Alzheimer's disease, in which progressive language impairment emerges as the most salient clinical feature during the initial stages of disease.

Group-level and functional-region analysis of electric-field shape during cerebellar transcranial direct current stimulation with different electrode montages.

Cerebellar transcranial direct current stimulation (ctDCS) is a neuromodulation scheme that delivers a small current to the cerebellum. In this work, we computationally investigate the distributions and strength of the stimulation dosage during ctDCS with the aim of determining the targeted cerebellar regions of a group of subjects with different electrode montages. Approach. We used a new inter-individual registration method that permitted the projection of computed electric fields (EFs) from individu...

Stealth research: lack of peer-reviewed evidence from healthcare unicorns.

In 2014, one of us (JPAI) wrote a viewpoint article coining the term "stealth research" for touted biomedical innovation happening outside the peer-reviewed literature in a confusing mix of "possibly brilliant ideas, aggressive corporate announcements, and mass media hype". These reflections were prompted by Theranos, a medical diagnosis start-up company; Theranos had not published any peer-reviewed papers [1] but made claims that its technology would "disrupt medicine." However, in contrast to the tech sec...

Compound tribo-electrostatic separation for recycling mixed plastic waste.

To separate mixed plastic wastes into pure components can hugely elevate their reusable value and reduce the environmental risks. This study proposes a compound process to handle mixed plastics wastes. The study used mixed plastic granules of polypropylene (PP), acrylonitrile butadiene styrene (ABS), poly vinyl chloride (PVC), and polystyrene (PS) as the feeding material. Vibrating and cyclone tribo-chargers were used to find charge performance of different granules. In vibrating tribo-charger the biggest g...

Relations between mode of birth delivery and timing of developmental milestones and adiposity in preadolescence: A retrospective study.

Cesarean delivery (CS) is an increasingly common mode of delivery comprising over 30% of all deliveries in the U.S. The long-term impact of this delivery mode on child development remains unclear.

Mutation Hotspots in the β-Catenin Gene: Lessons from the Human Cancer Genome Databases.

Mutations in the β-catenin gene () have been implicated in the pathogenesis of some cancers. The recent development of cancer genome databases has facilitated comprehensive and focused analyses on the mutation status of cancer-related genes. We have used these databases to analyze the mutations assembled from different tumor types. High incidences of mutations were detected in endometrial, liver, and colorectal cancers. This finding agrees with the oncogenic role of aberrantly activated β-catenin in epi...

DD-OFDM transmission over few-mode fiber based on direct vector mode multiplexing.

The fiber vector eigenmode based mode division multiplexing (VMDM) transmission over few-mode fiber (FMF) with the 1st-order cylinder vector beams (CVBs) has been demonstrated. The performances of generated CVB using q-plate (QP) have been characterized before and after transmission over the FMF respectively based on the high-order Poincaré sphere model and polarization grating (PG). The measured minimum mode isolations between the two CVBs (TM and TE modes) of the used 4-mode FMF are about 16.8 dB after t...

Brain network dynamics in schizophrenia: Reduced dynamism of the default mode network.

Complex human behavior emerges from dynamic patterns of neural activity that transiently synchronize between distributed brain networks. This study aims to model the dynamics of neural activity in individuals with schizophrenia and to investigate whether the attributes of these dynamics associate with the disorder's behavioral and cognitive deficits. A hidden Markov model (HMM) was inferred from resting-state functional magnetic resonance imaging (fMRI) data that was temporally concatenated across individua...

Characteristics of the paralysed diaphragm studied by M-mode ultrasonography.

M-mode ultrasonography might be useful for detecting hemidiaphragm paralysis. The objective of the present study was to describe the motion recorded by M-mode ultrasonography of both diaphragmatic leaves in patients with a pre-established diagnosis of hemidiaphragm paralysis.

Patterns of Fish Reproduction at the Interface Between Air and Water.

Although fishes by nature are aquatic, many species reproduce in such a way that their embryos are exposed to air either occasionally or constantly during incubation. We examine the ecological context and review specific examples of reproduction by fishes at the air-water interface, including fishes that do and do not breathe air. Four modes of reproduction at the air-water interface are described across 18 teleost Orders, from fresh water, estuaries and sea water. Mode 1, the most common type of reproducti...


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