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07:45 EST 15th November 2018 | BioPortfolio

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Showing "Human Genetics Centre University Oxford Deploys Univa Solutions" PubMed Articles 1–25 of 24,000+

Oxford Specialist Handbooks in Paediatrics - Paediatric Neurology: Rob Forsyth and Richard Newton (eds) : Published by Oxford University Press, UK; Third Edition: 2018; ISBN: 978-0-19-878444-9.


Viral-free generation and characterization of a human induced pluripotent stem cell line from dermal fibroblasts.

Peripheral dermal fibroblasts (DF) from a healthy 56 year old female were obtained from the Centre for Healthy Brain Ageing (CHeBA) Biobank, University of New South Wales, under the material transfer agreement with the University of Wollongong. DFs were reprogrammed via mRNA-delivered transcription factors into induced pluripotent stem cells (iPSCs). The generated iPSCs were confirmed to be pluripotent, capable of three germ layer differentiation and are thus a useful resource for creating iPSC-derived he...

Updates offer robust and fair approach to resolving patient safety incidents.

Sam Foster, Chief Nurse, Oxford University Hospitals, welcomes the recommendations emerging from the latest reviews and highlights the importance of investigating systemic, as well as human factors.


The Big Data Revolution and Human Genetics.

Tocilizumab in the treatment of severe and/or refractory vasculo-Behçet's disease: a single-centre experience in China.

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Accurate and adaptive imputation of summary statistics in mixed-ethnicity cohorts.

Methods based on summary statistics obtained from genome-wide association studies have gained considerable interest in genetics due to the computational cost and privacy advantages they present. Imputing missing summary statistics has therefore become a key procedure in many bioinformatics pipelines, but available solutions may rely on additional knowledge about the populations used in the original study and, as a result, may not always ensure feasibility or high accuracy of the imputation procedure.

The Developing Genome: An Introduction to Behavioral Epigenetics by David S. Moore, Oxford University Press, 2015.

Ureteral injuries during different types of hysterecomy: A 7-year series at a single university center.

Accidental ureteral injury with gynaecologic surgery, especially hysterectomy, represents a high risk of patient morbidity. The incidence may vary from centre to centre. As the introduction of new minimally invasive surgical techniques and instruments may have affected the incidence of ureteral injury, we de novo analysed the incidence data for the last seven years.

My Diagnostic Odyssey-A Call to Expand Access to Genomic Testing for the Next Generation.

I attended the NSIGHT Ethics and Policy Advisory Board's meeting on sequencing newborns as a research associate in a joint apprenticeship between the University of California, San Francisco, Institute for Human Genetics and the university's Program in Bioethics. But I also came to the meeting with a deeply personal perspective: I had spent nearly my entire childhood in search of a diagnosis and therefore was eager to hear the board's discussion on how to ethically include genomic sequencing early in life. G...

Correction: The population genetics of human disease: The case of recessive, lethal mutations.

[This corrects the article DOI: 10.1371/journal.pgen.1006915.].

Reply to the Comment Entitled "Association of FTO rs9939609 with Obesity".

BrainImageR: Spatiotemporal gene set analysis referencing the human brain.

Neuronal analyses such as transcriptomics, epigenetics, and genome-wide association studies must be assessed in the context of the human brain to generate biologically meaningful inferences. It is often difficult to access primary human brain tissue; therefore, approximations are made using alternative sources such as peripheral tissues or in vitro-derived neurons. Gene sets from these studies are then assessed for their association with the post-mortem human brain. However, most analyses of post-mortem dat...

The Level of Monocyte Chemoattractant Protein-1 May be Affected by Several Factors.

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Martin Method for Estimation of Low-Density Lipoprotein Cholesterol.

No Abstract.

Lack of Equipoise on Ankle block after Hallux Valgus Surgery?

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Reply to the Comment Entitled "Martin Method for Estimation of Low-Density Lipoprotein Cholesterol".

The genetics of human fertility.

Heritable variation in fitness-survival and reproduction-is the fuel of evolution by natural selection. Many human societies have dramatically reduced mortality before and during the prime reproductive years, making fertility a reasonably good proxy for the whole of fitness in much of our species. For this reason, empirical knowledge regarding the genetics of fertility must be an essential part of any framework for understanding past and ongoing trends in human adaptive evolution. Here we use R.A. Fisher's ...

Melancholic Habits: Burton's Anatomy and the Mind Sciences by Jennifer Radden Melancholic Habits: Burton's Anatomy and the Mind Sciences Jennifer Radden Oxford : Oxford University Press , 2017 , viii + 325 p., $45.00.

Dynamics of PI3K and Hippo signaling pathways during in vitro human follicle activation.

How does biochemical stimulation or inhibition of the PI3K/Akt/mTOR pathway affect the activation and the growth of human primordial follicles in vitro?

EUROCAT: an update on its functions and activities.

This paper provides an outline of the development and growth of EUROCAT, the European network of congenital anomaly registers. In recent years the network has been through a period of transition and change. The Central Register of data has transferred from the Ulster University to the EU Joint-Research-Centre, Ispra, Italy.The benefits of combining data from across Europe, from different populations and countries are described by the uses to which these data can be put. These uses include:. surveillance of ...

VarSome: The Human Genomic Variant Search Engine.

VarSome.com is a search engine, aggregator and impact analysis tool for human genetic variation and a community-driven project aiming at sharing global expertise on human variants.

Rheumatoid Arthritis: A Brief Overview of the Treatment.

Rheumatoid arthritis (RA) is a chronic inflammatory systemic autoimmune disease, affecting the joints with varying severity among patients. The risk factors include age, gender, genetics and environmental exposure (cigarette smoking, air pollutants and occupational). Many complications can follow such as permanent joint damage requiring arthroplasty, rheumatoid vasculitis and elty's syndrome requiring splenectomy if it remains unaddressed. As there is no cure for RA, the treatment goals are to reduce the pa...

Assessing university students' sexual risk behaviors as predictors of human papillomavirus (HPV) vaccine uptake behavior.

There exists a significant gap in vaccine coverage of the human papillomavirus (HPV) among college-aged students. This study assessed sexual risk-taking behavior among university students and analyzed predictors of HPV vaccine initiation and completion in this population.


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