PubMed Journals Articles About "Innovation Technology Initiates Clinical Trial Novel Replacement System" RSS

14:56 EST 16th December 2018 | BioPortfolio

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Showing "Innovation Technology Initiates Clinical Trial Novel Replacement System" PubMed Articles 1–25 of 51,000+

Evaluating the Completeness of

To date, although studies have been conducted to assess compliance with listing clinical trial information, to our knowledge there is nothing in the literature examining the completion and accuracy of clinical trial site information on .

Computer-Assisted Compared with Conventional Total Knee Replacement: A Multicenter Parallel-Group Randomized Controlled Trial.

We previously reported the short-term radiographic and functional results of a randomized controlled trial (RCT) comparing computer-assisted and conventionally performed total knee replacement. We currently report the 2-year clinical results from this trial.

Incorporating Innovation and New Technology into Cardiothoracic Surgery.

The appropriate implementation of new technology, root cause analysis of "imperfect" outcomes and the continuous reappraisal of postgraduate training are needed to improve the care of tomorrow's patients. Healthcare delivery remains one of the most expensive sectors in the United States and the application of new and expensive technology that is necessary for the advancement of this complex specialty must be aligned with providing the best care for our patients. There are a several pathways to innovation; o...

Clinical Trial Results Summary for Laypersons: A User Testing Study.

To apply "user testing" to maximize readability and acceptability of a Clinical Trial Results Laypersons Summary-a new European requirement.

Clinical and Radiological Outcome of a new Total Cervical Disc Replacement Design.

Non-randomized prospective and single center clinical trial of the ProDisc Vivo prosthesis.

Thinking Big for the Smallest Patients: Innovation in Pediatric Technology.

Pediatric Health Technology: Innovation Meets Imagination.

The Near-Term Viability and Benefits of eLabels for Patients, Clinical Sites, and Sponsors.

Current clinical trial labels are designed primarily to meet regulatory requirements. These labels have low patient and site utility, few are opened, and they have limited space and small fonts. As our world transitions from paper to electronic, an opportunity exists to provide patients with information about their investigational clinical trial product in a way that is more easily accessible, meets Health Authority requirements, and provides valuable additional information for the patient and caregiver.

The 'full stack' of healthcare innovation skills: combining clinical informatics with care delivery innovation.

Designing and testing an educational innovation.

Technology provides an opportunity to develop innovations to improve the way we teach. Developing educational innovations must be approached in a methodical and thorough manner to identify the educational gap and validate the innovation's success in filling the gap. A successful educational innovation requires a stepwise approach that includes needs assessment, design of intervention, testing and analysis, evaluation of intervention, and determination of learning retention.

Clinical Outcome After Rectal Replacement With Side-to-End, Colon-J-Pouch, or Straight Colorectal Anastomosis Following Total Mesorectal Excision: A Swiss Prospective, Randomized, Multicenter Trial (SAKK 40/04).

To compare, in a phase 3, prospective, randomized, multi-center clinical trial functional outcome of reconstruction procedures following total mesorectal excision (TME).

Implementation of a Low Frame-Rate Protocol and Noise-Reduction Technology to Minimize Radiation Dose in Transcatheter Aortic Valve Replacement.

Limiting radiation exposure is necessary in radiological procedures. This study evaluates the impact of a radiological low frame-rate protocol in a standard angiographic system and the implementation of a noise-reduction technology (NRT) on patient radiation exposure during transcatheter aortic valve replacement (TAVR).

10-year Outcomes of Cervical Disc Replacement with the BRYAN® Cervical Disc: Results from a Prospective, Randomized, Controlled Clinical Trial.

Prospective, randomized multicenter IDE Trial between May 2002 and October 2004.

Comparison of the Accuracy of the Novel PrisMax Continuous Renal Replacement Therapy System to the Classic Prismaflex System.

We assessed how the novel PrisMax continuous renal replacement therapy (CRRT) system performed in an international multicentre setting. The system has multiple novel tools aiming to increase accuracy and dose delivery.

Using home sensing technology to assess outcome and recovery after hip and knee replacement in the UK: the HEmiSPHERE study protocol.

Over 160 000 people with severe hip or knee pain caused by osteoarthritis undergo total hip (THR) or knee replacement (TKR) surgery each year in the UK within the National Health Service (NHS), and this number is expected to increase. Innovative approaches to evaluating surgical outcomes will be needed to respond to the increasing burden of joint replacement surgery. The Sensor Platform for Healthcare in a Residential Environment, Interdisciplinary Research Collaboration (SPHERE-IRC) have developed a syst...

Application of the MADS classification system in a "mega mammoth" stent trial: Feasibility and preliminary clinical implications.

We attempted to test the feasibility of application of the MADS classification system in the largest stent trial to date and evaluate the preliminary clinical implications of this approach.

Impact of oral rehabilitation on the quality of life of partially dentate elders in a randomised controlled clinical trial: 2 year follow-up.

This randomised clinical trial aimed to compare the impact of two different tooth replacement strategies for partially dentate older patients namely; removable partial dentures (RPDs) and functionally orientated treatment based on the shortened dental arch (SDA) concept, on Oral Health-related Quality of Life (OHrQOL).

The Symptoms and Clinical events associated with Automatic Reprogramming (SCARE) at replacement notification study.

Pacemaker patients experience battery depletion and activate their alert for replacement notification. Automatic reprogramming at replacement notification can result in loss of rate response and atrio-ventricular (AV) synchrony.

Addressing the paradox of the team innovation process: A review and practical considerations.

Facilitating team innovation is paramount to promoting progress in the science, technology, engineering, and math fields, as well as advancing national health, safety, prosperity, and welfare. However, innovation teams face a unique set of challenges due to the novelty and uncertainty that is core to the definition of innovation, as well as the paradoxical nature of idea generation and idea implementation processes. These and other challenges must be overcome for innovation teams to realize their full poten...

Will My Child Do Better if She Enrolls in a Clinical Trial?

The question of whether children with cancer who enroll in clinical trials have superior outcomes compared with those who do not participate has been pursued for more than 4 decades, and recent studies have provided conflicting answers. Whether clinical trial participation influences outcome has important implications for how clinicians should present trial participation to patients and families. Methodological challenges limit generalizations about the impact of clinical trial participation on outcome comp...

Challenges and opportunities for effective delivery of clinical genetic services in the U.S. healthcare system.

Demand for clinical genetics and genomics services is increasing. As discussed in this study, the clinical genetics and genomics workforce is small. How to meet the demand with a limited workforce requires innovation.

A new three-dimensional, print-on-demand temporomandibular prosthetic total joint replacement system: Preliminary outcomes.

The aim of this study is to present the preliminary clinical data on the OMX Temporomandibular Joint (TMJ) Prosthetic total joint replacement system.

Statistical Interactions in a Clinical Trial.

New statisticians entering industry tend to "test statistical interactions" whenever there is a need. However, in many real-world applications, especially in clinical development of new drugs, most interactions need to be estimated, instead of tested. In this manuscript, the distinction between hypothesis testing and estimation will be articulated, and the use of statistical interactions in clinical development programs will be discussed. According to ICH E-9, the treatment by subgroup interaction should no...

Definitions of event magnitudes, spatial scales, and goals for climate change adaptation and their importance for innovation and implementation.

We examine how core professional and institutional actors in the innovation system conceptualize climate change adaptation in regards to pluvial flooding-and how this influences innovation. We do this through a qualitative case study in Copenhagen with interconnected research rounds, including 32 semi-structured interviews, to strengthen the interpretation and analysis of qualitative data. We find that the term "climate change adaptation" currently has no clearly agreed definition in Copenhagen; instead, di...

The Barrow Innovation Center case series: Early clinical experience with a novel surgical instrument used to prevent intraoperative spinal cord injuries.

The Barrow Innovation Center comprises an educational program in medical innovation that enables residents to identify problems in patient care and to rapidly develop and implement solutions to these problems. Residents involved in this program noted an elevated risk of iatrogenic spinal cord injury during posterior cervical and thoracic procedures. The objective of this study was to describe this complication and a novel solution developed through a new innovation training program.

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