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PubMed Journals Articles About "Is Initial Response To Low Dose Risperidone Predictive For Outcome In Anxiety?" RSS

08:11 EST 17th November 2019 | BioPortfolio

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Showing "Initial Response Dose Risperidone Predictive Outcome Anxiety" PubMed Articles 1–25 of 25,000+

Social anxiety is associated with BNST response to unpredictability.

Anxiety disorders are highly prevalent and cause substantial suffering and impairment. Whereas the amygdala has well-established contributions to anxiety, evidence from rodent and nonhuman primate models suggests that the bed nucleus of the stria terminalis (BNST) may play a critical, and possibly distinct, role in human anxiety disorders. The BNST mediates hypervigilance and anticipatory anxiety in response to an unpredictable or ambiguous threat, core symptoms of social anxiety, yet little is known about ...


Significance of anti-HB levels below 10 IU/L after vaccination against hepatitis B in infancy or adolescence: an update in relation to sex.

Hepatitis B vaccination (three-dose series) induces long-term immunity, but it is not uncommon to find antibody levels below 10 IU/L long after vaccination. However, the majority of the subjects with low antibody levels have a prompt response to a booster dose. A population of 10,294 students at Padua University Medical School, who were subjected to hepatitis B vaccination during infancy or adolescence according to the law, was tested for the presence of anti-HBs, usually during the first year of matriculat...

Hospitalization risk in patients with schizophrenia treated with dose-equivalent antipsychotics.

This study compared the risk of hospitalization among adults with schizophrenia being treated with equivalent dose ranges of lurasidone versus aripiprazole, olanzapine, quetiapine, or risperidone. Administrative claims data for this analysis came from the IBM MarketScan Commercial, Medicare Supplemental, and Multi-State Medicaid databases between January 2011 and June 2017. The study included adults with schizophrenia who initiated treatment with an antipsychotic and were continuously enrolled for 360 days ...


Initiation of a fixed-dose four-factor prothrombin complex concentrate protocol.

Patients who require urgent warfarin reversal often receive four-factor prothrombin complex concentrate (4F-PCC), which is traditionally dosed according to weight and initial INR. Our institution implemented a fixed-dose 4F-PCC strategy, using an initial dose of 1500 units. We evaluated the frequency with which the initial fixed dose 4F-PCC was inadequate, as defined by need for supplemental dosing. As part of the protocol, if the initial fixed-dose 4F-PCC is administered and does not achieve INR goal, then...

Efficacy between low and high dose aspirin for the initial treatment of Kawasaki disease: Current evidence based on a meta-analysis.

Kawasaki disease (KD) is now the leading cause of acquired heart disease in children in developed countries. Intravenous immunoglobulin (IVIG) and aspirin were considered as the standard initial treatment of KD for decades. However, the optimal dose of aspirin has remained controversial. In recent years, many studies compared the efficacy of low-dose with high-dose aspirin in the acute phase of KD, but the results have not always been consistent. Therefore, we performed this meta-analysis to evaluate the ef...

Response by Pompilio et al to Letter Regarding Article, "G-CSF for Extensive STEMI: Results From the STEM-AMI OUTCOME CMR Substudy".

The longitudinal course of pregnancy-related anxiety in parous and nulliparous women and its association with symptoms of social and generalized anxiety.

There is evidence that pregnancy-related anxiety (PrA) has a negative impact on birth outcomes and infant development. However, little is known about worrisome levels and individual trajectories of PrA dimensions across pregnancy and their predictive factors, particularly the association of PrA with symptoms of social phobia (SP) and generalized anxiety disorder (GAD).

Ultrasonic Vocalization Sex Differences in 5-HT-R Deficient Mouse Pups: Predictive Phenotypes Associated with Later-life Anxiety-like Behaviors.

Anxiety disorders affect nearly twice as many women as men. However, little is known regarding sex-dependent developmental behavioral differences and whether there is an association with later life anxiety disorders. The present study assessed the developmental-behavioral milestones (DBMs) and their relationship with later life anxiety-like behaviors by comparing postnatal ultrasonic vocalizations (USVs) with open field (OF), elevated plus maze (EPM), and light/dark (LD) anxiety test outcomes using the sero...

Discrete Electrocortical Predictors of Anxiety and Anxiety-Related Treatment Response in Youth with Autism Spectrum Disorder.

There are two established electroencephalogram (EEG) indices that putatively relate to anxiety symptoms: a) the error-related negativity (ERN), which reflects endogenous threat sensitivity, and b) resting-state EEG relative right frontal activity (rRFA), which relates to approach/withdrawal motivation. We examined these indices conjointly to better elucidate differential mechanisms underlying the common anxiety phenotype in youth with autism spectrum disorder (ASD), in relation to subjective reports of symp...

Definition of the Response to Initial Therapy with Radioiodine in Patients with Differentiated Thyroid Carcinoma: Basal or Stimulated Thyroglobulin?

Basal thyroglobulin (b-Tg) measured with second-generation assay or stimulated Tg (s-Tg) can be used to define the response to therapy of differentiated thyroid carcinoma. However, they do not always define the same category and guidelines do not establish "if" or "when" s-Tg needs to be obtained. We studied 304 patients without clinically apparent disease or disease detected by neck ultrasonography and without anti-Tg antibodies 9-12 months after therapy. Based on b-Tg, 196 patients had an excellent respon...

Predictive cues reduce but do not eliminate intrinsic response bias.

Predictive cues induce large changes in people's choices by biasing responses towards the expected stimulus category. At the same time, even in the absence of predictive cues, humans often exhibit substantial intrinsic response biases. Despite the ubiquity of both of these biasing effects, it remains unclear how predictive cues interact with intrinsic bias. To understand the nature of this interaction, we examined data across three previous experiments that featured a combination of neutral cues (revealing ...

Characterizing Anxiety at the First Encounter in women presenting to the urogynecology clinic: the CAFÉ Study.

Clinically based anxiety questionnaires measure 2 forms of anxiety known as state anxiety and trait anxiety. State anxiety is temporary and is sensitive to change, while trait anxiety is a generalized propensity to be anxious.

Response to "Letter to the editors in regard to the article 'Predictive score for oral corticosteroid-induced initial worsening of seropositive generalized myasthenia gravis'".

Anxiety-associated and separation distress-associated behaviours in Angelman syndrome.

Anxiety is considered a 'frequent' feature in the clinical criteria for Angelman syndrome; however, the nature and severity of anxiety symptoms have not been well characterised in this population. Anxiety behaviours, especially in response to separation from a preferred caregiver, have been described clinically but have not yet been explored empirically.

Factors Associated With Response to Adapted Cognitive Behavioral Therapy for Anxiety and Depression Following Traumatic Brain Injury.

Given the high frequency and significance of anxiety and depression following traumatic brain injury (TBI), there is a need to evaluate the efficacy of psychological interventions and to understand factors influencing response to such interventions. The present study investigated factors associated with positive response to cognitive behavioral therapy adapted for cognitive impairments (CBT-ABI) for individuals with anxiety and depression following TBI, including demographic and injury-related factors, pret...

Integrative Approaches to Stress, Anxiety, and Resilience.

Anxiety is one of the most common psychiatric conditions affecting adolescents and youth in the United States, with over 30% of adolescents having an anxiety disorder of any type. The conventional approach to anxiety management can include medications that in some patient populations can increase the risk of suicidality. Untreated anxiety and sequela of anxiety can have a significant impact on the life of a child and can impact them into adulthood. Integrative treatments in the setting of anxiety and stress...

The predictive role of self-compassion in cancer patients' symptoms of depression, anxiety, and fatigue: a longitudinal study.

Self-compassion is consistently found to be related to better psychological outcomes. As most studies were cross-sectional, little is known about the predictive role of self-compassion for future psychological outcomes. This longitudinal study in cancer patients investigated the predictive role of self-compassion at the time of cancer diagnosis for the course of symptoms of depression, anxiety, and fatigue in the period of receiving cancer treatment.

Leuco crystal violet-Pluronic F-127 3D radiochromic gel dosimeter.

This work reports results related to the manufacturing and optimisation of a leuco crystal violet (LCV)-Pluronic F-127 radiochromic gel dosimeter suitable for 3D radiotherapy dosimetry. A feature of this gel is that the natural gelatine polymer, which is most often used as a matrix in 3D dosimeters, is substituted with Pluronic F-127 synthetic copolymer (poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide). Pluronic F-127 ensures a higher transparency than gelatine, which may be benef...

Relationships between allopurinol dose, oxypurinol concentration and urate-lowering response - in search of a minimum effective oxypurinol concentration.

The aims of this study were to determine factors that predict serum urate (SU) lowering response to allopurinol and the conversion of allopurinol to oxypurinol, and to determine a minimum therapeutic oxypurinol concentration. Data from 129 participants in a 24-month open, randomized, controlled, parallel-group, comparative clinical trial were analysed. Allopurinol dose, serum urate and plasma oxypurinol concentrations were available at multiple time points. The slope for the association between allopurinol ...

Python BMDS: A Python interface library and web application for the canonical EPA dose-response modeling software.

Several primary sources of publicly available, quantitative dose-response data from traditional toxicology study designs relevant to predictive toxicology applications are now available, including the redeveloped U.S. Environmental Protection Agency's Toxicity Reference Database (ToxRefDB v2.0), the Health Assessment Workspace Collaborative (HAWC), and the National Toxicology Program's Chemical Program's Chemical Effects in Biological Systems (CEBS). These resources provide effect level information but mode...

The two faces of nanomaterials: A quantification of hormesis in algae and plants.

The rapid progress in nanotechnology has dramatically promoted the application of engineered nanomaterials in numerous sectors. The wide application of nanomaterials and the potential accumulation in the environment sparked interest in studying the effects of nanomaterials on algae and plants. Hormesis is a dose response phenomenon characterized by a biphasic dose response with a low dose stimulation and a high dose inhibition. This paper quantifies for the first time nanomaterial-induced hormesis in algae ...

Comparison of the association of risperidone and quetiapine with deteriorating performance in walking and dressing in subjects with Parkinson's disease: a retrospective cohort study using administrative claims data.

This retrospective cohort study was performed to investigate the association between risperidone and deteriorating performance in walking and dressing in subjects with Parkinson's disease using the Japanese Diagnosis Procedure Combination data. These data include inpatient claims including information from the time of admission to discharge from 89 acute phase National Hospitals in Japan. The data were evaluated by implementing the inverse probability of treatment weighting, using propensity scores estimate...

SKA2 gene - A novel biomarker for latent anxiety and preterm birth prediction.

There is a relationship between preterm birth (PTB) and anxiety. Spindle and Kinetochore Associated Complex Subunit 2 (SKA2) gene polymorphism (NC_000017.11: g.59110368 G > A) has also been associated with the development of anxiety. The current study was designed to evaluate the relationship between SKA2 gene SNP (NC_000017.11: g.59110368 G > A) with the occurrence of anxiety and PTB which might be considered a predictive biomarker for the prediction of preterm delivery.

The superior predictive value of Ho-scout compared with Tc-macroaggregated albumin prior to Ho-microspheres radioembolization in patients with liver metastases.

As an alternative to technetium-99m-macroaggregated albumin (Tc-MAA), a scout dose of holmium-166 (Ho) microspheres can be used prior to Ho-radioembolization. The use of identical particles for pre-treatment and treatment procedures may improve the predictive value of pre-treatment analysis of distribution. The aim of this study was to analyze the agreement between Ho-scout and Ho-therapeutic dose in comparison with the agreement between Tc-MAA and Ho-therapeutic dose.

The risk of bone fracture after long-term risperidone exposure is not increased compared to other atypical antipsychotics: A retrospective cohort study.

Antipsychotic agents can increase circulating serum prolactin levels, potentially leading to osteoporosis and increased risk of bone fracture. The risk appears to be lower for atypical antipsychotics. We investigated whether risperidone was associated with an increased fracture risk by estimating the incidence of hip/femur and non-hip/femur fractures in users of risperidone, other atypical, and typical antipsychotics.


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