PubMed Journals Articles About "LUNAR DREAM CAPSULE PROJECT" RSS

00:49 EST 18th November 2018 | BioPortfolio

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Showing "LUNAR DREAM CAPSULE PROJECT" PubMed Articles 1–25 of 1,600+

Diagnostic utility of DREAM gene mRNA levels in thyroid tumours.

The transcriptional repressor DREAM is involved in thyroid-specific gene expression, thyroid enlargement and nodular development, but its clinical utility is still uncertain. In this study we aimed to investigate whether DREAM mRNA levels differ in different thyroid tumors and how this possible difference would allow the use of DREAM gene expression as molecular marker for diagnostic and/or prognosis purpose.

Pb2+ Binds to DREAM and Modulates Its Interactions with Binding Partners: a Link between Neuronal Calcium Sensors and Pb2+ Neurotoxicity.

Pb exposure leads to diverse neurological disorders; however, the mechanism of Pb-induced neurotoxicity is not clearly understood. Here we demonstrate that Pb binds to EF-hands in DREAM (Downstream regulatory element antagonist modulator) with a lower equilibrium dissociation constant (K = 20 ± 2 nM) than Ca (K = 1μM). Based on the Trp 169 emission and CD spectra, we report that Pb association triggers changes in the protein secondary and tertiary structures that are analogous to those previously observed...

Pre-sleep treatment with galantamine stimulates lucid dreaming: A double-blind, placebo-controlled, crossover study.

Lucid dreaming is a remarkable state of consciousness in which one is aware of the fact that one is dreaming while continuing to dream. Based on the strong relationship between physiological activation during rapid eye-movement sleep and lucid dreaming, our pilot research investigated whether enhancing cortical activation via acetylcholinesterease inhibition (AChEI) would increase the frequency of lucid dreams and found AChEI to be a promising method for lucid dream induction. In the current study we sought...

Exploring the effects of galantamine paired with meditation and dream reliving on recalled dreams: Toward an integrated protocol for lucid dream induction and nightmare resolution.

An experimental home study examined the impact of a pre-sleep protocol for enhancing self-awareness, lucidity, and responsiveness in dreams. It included ingesting the cholinesterase inhibitor galantamine--which is widely reported to increase the frequency of lucid dreaming--prior to engaging in middle-of-the-night meditation and the imaginary reliving of a distressing dream while exercising new responses. Thirty-five participants completed an eight-night study, which included pre- and post-baseline nights a...

Expression and contribution to virulence of each polysaccharide capsule of Bacillus cereus strain G9241.

Bacillus cereus strain G9241 was isolated from a patient with pneumonia who had an anthrax-like illness. Like Bacillus anthracis, the virulence of G9241 is dependent on two large plasmids. In G9241 those plasmids are pBCXO1 and pBC210. There is a multi-gene capsule locus on each of these virulence plasmids, and both capsules are produced by G9241 in vitro and in mice. The hasACB operon on pBCXO1 is responsible for production of a hyaluronic acid (HA) capsule. The locus on pBC210 encodes a putative tetrasacc...

Spontaneous point mutations in the capsule synthesis locus leading to structural and functional changes of the capsule in serogroup A meningococcal populations.

Whole genome sequencing analysis of 100 Neisseria meningitidis serogroup A isolates has revealed that the csaABCD-ctrABCD-ctrEF capsule polysaccharide synthesis locus represents a spontaneous point mutation hotspot. Structural and functional properties of the capsule of 11 carriage and two disease isolates with non-synonymous point mutations or stop codons in capsule synthesis genes were analyzed for their capsular polysaccharide expression, recognition by antibodies and sensitivity to bactericidal killing....

Rapid measurement and compensation method of eccentricity in automatic profile measurement of the ICF capsule.

In this paper, we propose a new measurement and compensation method for the eccentricity of the inertial confinement fusion (ICF) capsule, which combines computer vision and the laser differential confocal method to align the capsule in rotation measurement. This technique measures the eccentricity of the capsule by obtaining the sub-pixel profile with a moment-based algorithm, then performs the preliminary alignment by the two-dimensional adjustment. Next, we use the laser differential confocal sensor to m...

Living in Two Worlds. How 'Jungian' am I?

As a so-called 'Developmental Jungian' the author of this paper was raised bilingual - speaking both psychoanalytic and Jungian languages. Early on in her training an analysand brought a dream which seemed to capture an inherent tension regarding the analyst's role in the analytic relationship. The paper is a personal exploration of the potentially creative nature of this tension through focussing on the dream and the work with the dreamer.

Diagnostic yield of magnetically assisted capsule endoscopy versus gastroscopy in recurrent and refractory iron deficiency anemia.

 Small-bowel capsule endoscopy is advocated and repeat upper gastrointestinal (GI) endoscopy should be considered for evaluation of recurrent or refractory iron deficiency anemia (IDA). A new device that allows magnetic steering of the capsule around the stomach (magnetically assisted capsule endoscopy [MACE]), followed by passive small-bowel examination might satisfy both requirements in a single procedure.

Significance of distance between tumor and thyroid capsule as an indicator for central lymph node metastasis in clinically node negative papillary thyroid carcinoma patients.

The aim of this study was to evaluate preoperatively identifiable clinical and ultrasonographic characteristics associated with central lymph node metastasis (CLNM) in clinically node negative papillary thyroid carcinoma (PTC) patients. Records of the patients who underwent thyroidectomy with prophylactic central lymph node dissection due to clinically node negative PTC (size, 1.0-3.0 cm) were reviewed. Of a total of 174 patients, 71 (40.8%) had CLNMs. CLNM was more associated with capsule invasion than cap...

Using the Logic Model Framework to Standardize Quality and Rigor in the DNP Project.

Since the implementation of the DNP degree, there has been controversy, confusion, and inconsistency about the DNP project. To this day, the profession lacks a consensus of what the DNP project should be.

Favorite odor induces negative dream emotion during rapid eye movement sleep.

As connections between nightmares and various psychiatric disorders have been reported, the clinical significance of studying dream emotionality is now growing in importance. Because the olfactory bulb connects directly to the amygdala odor presentation may be a crucial tool to study dream emotions. Previous studies have demonstrated that presentation of positive/negative odors during rapid eye movement (REM) sleep affects various aspects of dreaming. Although olfactory perception can be influenced by perso...

Detection of infection mimicking Crohn's disease using video capsule endoscopy.

Capsule endoscopy was used to detect intestinal infection in a 19-year-old man. The patient was initially believed to have Crohn's disease due to a notable family history of the disease. Capsule endoscopy is a valuable tool for diagnosing tapeworm infection even when Crohn's disease is suspected.

Characterization of capsule genes in non-pathogenic Neisseria species.

The genus Neisseria comprises a diverse group of commensal bacteria, which typically colonize the mucosal surfaces of humans and other animals. Neisseria meningitidis, the meningococcus, is notable for its potential to cause invasive meningococcal disease (IMD) in humans; however, IMD is comparatively rare, and meningococci normally colonize the nasopharynx asymptomatically. Possession of a polysaccharide capsule has been shown to be a prerequisite for disease in almost all IMD cases, and was previously con...

The dry eye assessment and management (DREAM©) study: Study design and baseline characteristics.

Describe trial design and baseline characteristics of participants in the DRy Eye Assessment and Management (DREAM©) Study.

Technology for improving accessibility of end-of-life care: Extension for Community Healthcare Outcomes Project.

To describe how Project ECHO works and to analyze what has been published on Project ECHO Palliative Care (Project ECHO PC) over the last 18 months.

Prevalence of Novel Candidate Sjogren Syndrome Autoantibodies in the Dry Eye Assessment and Management (DREAM) Study.

To evaluate the prevalence of novel candidate Sjogren syndrome (SS) autoantibodies [salivary protein-1 (SP-1), parotid secretory protein, carbonic anhydrase 6] in the DRy Eye Assessment and Management (DREAM) cohort, a study evaluating the effectiveness of omega-3 fatty acid supplements for the treatment of dry eye.

Capsule endoscopy findings for the diagnosis of Crohn's disease: a nationwide case-control study.

Capsule endoscopy can be used to identify the early stage of small bowel Crohn's disease (CD). We evaluated significant small bowel capsule endoscopy (SBCE) findings that can lead to early diagnosis of CD.

Primary Stability of an Acromioclavicular Joint Repair Is Affected by the Type of Additional Reconstruction of the Acromioclavicular Capsule.

The synergistic effect of the acromioclavicular (AC) capsule and coracoclavicular (CC) ligaments on AC joint stability has gained recent recognition for its importance. Biomechanical and clinical studies have shown the benefit of combined reconstruction with multiple variations of surgical techniques for AC capsule augmentation. The ideal configuration remains unknown for such capsular repair aimed at achieving optimal stability with anatomic reconstruction.

The project vita: A dynamic knowledge management tool.

A project vita is a comprehensive index of factual information about a project's activities and achievements. Like an individual's professional curriculum vita or resume, it serves as evidence of past performance and capacity for future endeavors. This article situates the project vita as a knowledge management tool for use by large-scale research and development projects or coalitions. In such complex endeavors, the variety and scope of the knowledge generated can quickly outpace project staff attempts to ...

Nuanxin capsule for heart failure: A systematic review of randomized controlled trials.

To assess the efficacy and safety of Nuanxin capsule for patients with heart failure (HF).

Impact of capsule type on aerodynamic performance of inhalation products: a case study using a formoterol-lactose binary or ternary blend.

The aerodynamic performance of a dry powder for inhalation depends on the formulation and the dry powder inhaler (DPI). In the case of capsule-based DPIs, the capsule also plays a role in the powder aerosolisation and the dispersion of the micronized drug during the inhalation. This study evaluated the impact of gelatine capsules (Quali-G and Hard Gelatine Capsules for DPIs), cold-gelled hypromellose (HPMC) capsules (Quali-V-I and Vcaps) and thermal-gelled HPMC capsules (VcapsPlus) from Qualicaps and Capsug...

We Have to Dream Big.

Rochester Epidemiology Project Data Exploration Portal.

The goal of this project was to develop an interactive, web-based tool to explore patterns of prevalence and co-occurrence of diseases using data from the expanded Rochester Epidemiology Project (E-REP) medical records-linkage system.

Dream of a Dying Man.

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