Advertisement

Topics

PubMed Journals Articles About "M*Modal Inc." RSS

06:04 EDT 23rd July 2018 | BioPortfolio

M*Modal Inc. PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest M*Modal Inc. articles that have been published worldwide.

More Information about "M*Modal Inc." on BioPortfolio

We have published hundreds of M*Modal Inc. news stories on BioPortfolio along with dozens of M*Modal Inc. Clinical Trials and PubMed Articles about M*Modal Inc. for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of M*Modal Inc. Companies in our database. You can also find out about relevant M*Modal Inc. Drugs and Medications on this site too.

Showing "Modal" PubMed Articles 1–25 of 218

Integrin αβ receptor targeting PET/MRI dual-modal imaging probe based on the Cu labeled manganese ferrite nanoparticles.

With the advent of positron emission tomography/magnetic resonance imaging (PET/MRI) scanner, PET/MRI dual-modal imaging will play more and more important role in the diagnosis of cancers and other diseases. Until now, there is no an approved PET/MRI dual-modal imaging probe. The goal of this work is to design and synthesize potential PET/MRI dual-modal imaging probe based on superparamagnetic manganese ferrite nanoparticles. We have developed superparamagnetic nanoparticles that have uniform size with 5 ...


A self-assessed photosensitizer: inducing and dual-modal phosphorescence imaging of mitochondria oxidative stress.

Two novel Ir(iii)-nitroxide conjugates have been synthesized as mitochondria-targeted multi-functional theranostic photosensitizers, capable of simultaneously inducing and dual-modal phosphorescence imaging of mitochondrial oxidative stress under two-photon excitation, thus realizing the photodynamic therapy of cancer and self-assessment of their PDT efficacies.

Dual-modal photoacoustic and magnetic resonance tracking of tendon stem cells with PLGA/iron oxide microparticles in vitro.

Reliable cell tracking is essential to understand the fate of stem cells following implantation, and thus promote the clinical application of stem cell therapy. Dual or multiple modal imaging modalities mediated by different types of multifunctional contrast agent are generally needed for efficient cell tracking. Here, we created a new contrast agent-PLGA/iron oxide microparticles (PLGA/IO MPs) and characterized the morphology, structure and function of enhancing both photoacoustic (PA) and magnetic resonan...


Synthesis, Characterization and Biomedical Applications of a Targeted Dual-Modal Near Infrared-II Fluorescence and Photoacoustic Imaging Nanoprobe.

Our development of multifunctional dual-modal imaging probes aims to integrate the benefits from both NIR-II fluorescence (1000 - 1700 nm) and photoacoustic imaging with an ultimate goal of improving overall cancer diagnosis efficacy. Herein we designed a donor-acceptor chromophore based nanoparticle (DAP) as a novel dual-modal image contrast agent which has strong absorption in the NIR-I window and a strong fluorescence emission peak in the NIR-II region. The dual-modal DAPs composed of D-π-A-π-D type ch...

Neural practice effect during cross-modal selective attention: Supra-modal and modality-specific effects.

Practice and experiences gradually shape the central nervous system, from the synaptic level to large-scale neural networks. In natural multisensory environment, even when inundated by streams of information from multiple sensory modalities, our brain does not give equal weight to different modalities. Rather, visual information more frequently receives preferential processing and eventually dominates consciousness and behavior, i.e., visual dominance. It remains unknown, however, the supra-modal and modali...

Phosphorylation of an intrinsically disordered region of Ets1 shifts a multi-modal interaction ensemble to an auto-inhibitory state.

Multi-modal interactions are frequently observed in intrinsically disordered regions (IDRs) of proteins upon binding to their partners. In many cases, post-translational modifications in IDRs are accompanied by coupled folding and binding. From both molecular simulations and biochemical experiments with mutational studies, we show that the IDR including a Ser rich region (SRR) of the transcription factor Ets1, just before the DNA-binding core domain, undergoes multi-modal interactions when the SRR is not ph...

Cortical structural involvement and cognitive dysfunction in early Parkinson's disease.

Magnetic resonance imaging (MRI) studies in early Parkinson's disease (PD) have shown promise in the detection of disease-related brain changes in the white and deep grey matter. We set out to establish whether intrinsic cortical involvement in early PD can be detected with quantitative MRI. We collected a rich, multi-modal dataset, including diffusion MRI, T1 relaxometry and cortical morphometry, in 20 patients with early PD (disease duration, 1.9 ± 0.97 years, Hoehn & Yahr 1-2) and in 19 matched control...

Achieving a high mode count in the exact electromagnetic simulation of diffractive optical elements.

The application of rigorous optical simulation algorithms, both in the modal as well as in the time domain, is known to be limited to the nano-optical scale due to severe computing time and memory constraints. This is true even for today's high-performance computers. To address this problem, we develop the fast rigorous iterative method (FRIM), an algorithm based on an iterative approach, which, under certain conditions, allows solving also large-size problems approximation free. We achieve this in the case...

Affect recognition from facial movements and body gestures by hierarchical deep spatio-temporal features and fusion strategy.

Affect presentation is periodic and multi-modal, such as through facial movements, body gestures, and so on. Studies have shown that temporal selection and multi-modal combinations may benefit affect recognition. In this article, we therefore propose a spatio-temporal fusion model that extracts spatio-temporal hierarchical features based on select expressive components. In addition, a multi-modal hierarchical fusion strategy is presented. Our model learns the spatio-temporal hierarchical features from video...

Evaluating the Effect of In-Process Material on the Binding Mechanisms of Surrogate Viral Particles to a Multi-Modal Anion Exchange Resin.

Bacteriophage binding mechanisms to multi-modal anion exchange resin may include both anion exchange and hydrophobic interactions, or the mechanism can be dominated by a single moiety. However, previous studies have reported binding mechanisms defined for simple solutions containing only buffer and a surrogate viral spike (i.e. bacteriophage ΦX174, PR772, and PP7). We employed phage spiked in-process monoclonal antibody (mAb) pools to model binding under bioprocessing conditions. These experiments allow th...

Multifunctional Bi@PPy-PEG Core-Shell Nanohybrids for Dual-Modal Imaging and Photothermal Therapy.

High-performance theranostic nanoagents which integrate multi-modal imaging and photothermal therapy for clinical anticancer treatment are highly desired. Herein, we report the synthesis and bio-application of a multifunctional theranostic nanoagent based on polyethylene glycol (PEG)-modified polypyrrole (PPy)-coated bismuth (Bi) nanohybrids (referred as Bi@PPy-PEG NHs) for X-ray computed tomography/photoacoustic (CT/PA) dual-modal imaging and photothermal therapy (PTT). The obtained Bi@PPy-PEG NHs have a ...

Modal Parameters Evaluation in a Full-Scale Aircraft Demonstrator under Different Environmental Conditions Using HS 3D-DIC.

In real aircraft structures the comfort and the occupational performance of crewmembers and passengers are affected by the presence of noise. In this sense, special attention is focused on mechanical and material design for isolation and vibration control. Experimental characterization and, in particular, experimental modal analysis, provides information for adequate cabin noise control. Traditional sensors employed in the aircraft industry for this purpose are invasive and provide a low spatial resolution....

Matched coordinates in the framework of polynomial modal methods for complex metasurface modeling.

The polynomial modal method (PMM) is one of the most powerful methods for modeling diffraction from lamellar gratings. In the present work, we show that applying it to the so-called matched coordinates leads to important improvement of convergence for crossed lamellar gratings with patterns that are not parallel to the coordinates' axes. After giving the new formulation of the PMM under matched coordinates in the general framework of biperiodic structures, we provide numerical examples to demonstrate the ef...

Assessing cross-modal target transition effects with a visual-auditory oddball.

Prior research has shown contextual manipulations involving temporal and sequence related factors significantly moderate attention-related responses, as indexed by the P3b event-related-potential, towards infrequent (i.e., deviant) target oddball stimuli. However, significantly less research has looked at the influence of cross-modal switching on P3b responding, with the impact of target-to-target cross-modal transitions being virtually unstudied. To address this gap, this study recorded high-density (256 e...

Cross-modal cueing effects of visuospatial attention on conscious somatosensory perception.

The impact of visuospatial attention on perception with supraliminal stimuli and stimuli at the threshold of conscious perception has been previously investigated. In this study, we assess the cross-modal effects of visuospatial attention on conscious perception for near-threshold somatosensory stimuli applied to the face.

Defining the Mechanistic Binding of Viral Particles to a Multi-Modal Anion Exchange Resin.

A multi-tiered approach to determine the binding mechanism of viral clearance utilizing a multi-modal anion exchange resin was applied to a panel of four viral species that are typically used in validating viral clearance studies (i.e., X-MuLV, MVM, REO3, and PrV). First, virus spiked buffer-only experiments were conducted to evaluate the virus's affinity for single mode and multi-modal chromatography resins under different buffer conditions in a chromatography column setting. From these results we hypothes...

Big data sharing and analysis to advance research in post-traumatic epilepsy.

We describe the infrastructure and functionality for a centralized preclinical and clinical data repository and analytic platform to support importing heterogeneous multi-modal data, automatically and manually linking data across modalities and sites, and searching content. We have developed and applied innovative image and electrophysiology processing methods to identify candidate biomarkers from MRI, EEG, and multi-modal data. Based on heterogeneous biomarkers, we present novel analytic tools designed to ...

The effect of a tactile-to-visual shift on young children's tendency to map novel labels onto novel objects.

When taught a label for an object and then asked whether an exemplar of that object or a novel object is the referent of a novel label, children favor the novel object. Preschool-aged children tend not to show this so-called disambiguation effect, however, when the test objects are presented in a different sense modality than the original object. The current experiments used a touch-to-vision paradigm to test two explanations for this unexpected pattern. Experiment 1 asked whether children might fail to ret...

Experimental study of isolas in nonlinear systems featuring modal interactions.

The objective of the present paper is to provide experimental evidence of isolated resonances in the frequency response of nonlinear mechanical systems. More specifically, this work explores the presence of isolas, which are periodic solutions detached from the main frequency response, in the case of a nonlinear set-up consisting of two masses sliding on a horizontal guide. A careful experimental investigation of isolas is carried out using responses to swept-sine and stepped-sine excitations. The experimen...

Monitoring pipe wall integrity using fiber Bragg grating-based sensing of low-frequency guided ultrasonic waves.

Recent literature shows that low-frequency ultrasonic guided waves experience mode confinement and loss of axi-symmetry in pipes with axially uniform features such as eccentricity. Considering extended wall loss as a case of uniform eccentricity, this paper proposes to monitor pipe integrity by measuring changes to the modal structure of low-frequency axisymmetric L(0,2) longitudinal guided waves. Fiber Bragg gratings are shown to be effective in detecting changes to L(0,2) modal characteristics, providing ...

Investigating common coding of observed and executed actions in the monkey brain using cross-modal multi-variate fMRI classification.

Mirror neurons are generally described as a neural substrate hosting shared representations of actions, by simulating or 'mirroring' the actions of others onto the observers' own motor system. Since single neuron recordings are rarely feasible in humans, it has been argued that cross-modal multi-variate pattern analysis (MVPA) of non-invasive fMRI data is a suitable technique to investigate common coding of observed and executed actions, allowing researchers to infer the presence of mirror neurons in the hu...

Mechanistic Insights into Human Brain Impact Dynamics through Modal Analysis.

Although concussion is one of the greatest health challenges today, our physical understanding of the cause of injury is limited. In this Letter, we simulated football head impacts in a finite element model and extracted the most dominant modal behavior of the brain's deformation. We showed that the brain's deformation is most sensitive in low frequency regimes close to 30 Hz, and discovered that for most subconcussive head impacts, the dynamics of brain deformation is dominated by a single global mode. In...

Higher-order cladding mode excitation of femtosecond-laser-inscribed tilted FBGs.

We study the modal behavior of plane-by-plane femtosecond laser fabricated tilted fiber Bragg gratings (FBGs). The focus is on the differential strain and temperature sensitivities between the cladding mode resonances of an nth grating order and those of the (n-i)th orders (with i=1-n), which are collocated in the same wavelength range. Whereas the Bragg mode exhibits an axial strain sensitivity of 1.2 pm/μϵ, we experimentally show that the strain sensitivity of ultrahigh-order cladding modes is negative...

Optically powered radio-over-fiber system based on center- and offset-launching techniques using a conventional multimode fiber.

We demonstrate radio-over-fiber (RoF) transmission with a 10-W feed power-over-fiber (PWoF) using a conventional multimode fiber (MMF). In this scheme, the modal dispersion and feed light crosstalk in the MMF are effectively mitigated by the combination of center-launching (CL) and offset-launching (OL) techniques. The CL is used for propagating the feed light into lower-order modes in the MMF, while the OL is used not only for propagating the optical data signals into higher-order modes in the MMF, but als...

Dual-modal split-type immunosensor for sensitive detection of microcystin-LR: enzyme-induced photoelectrochemistry and colorimetry.

Microcystins, the lethal cyanotoxins from microcystis aeruginosa, can inhibit the activity of protein phosphatase and promote liver tumor. Herein, a dual-modal split-type immunosensor was constructed to detect microcystin-LR (MC-LR), basing on the photocurrent change of CdS/ZnO hollow nanorod arrays (HNRs) and the blue-shift of surface plasmon resonance peak from Au nanobipyramids@Ag. By using mesoporous silica nanospheres as the carrier to immobilize second-ary antibody and DNA primer, hybridization chain ...


Advertisement
Quick Search
Advertisement
Advertisement