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15:55 EST 14th December 2017 | BioPortfolio

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Showing "MEDNAX 2017 Results Earnings Call Transcript" PubMed Articles 1–25 of 41,000+

Return to work and lost earnings after acute respiratory distress syndrome: a 5-year prospective, longitudinal study of long-term survivors.

Delayed return to work is common after acute respiratory distress syndrome (ARDS), but has undergone little detailed evaluation. We examined factors associated with the timing of return to work after ARDS, along with lost earnings and shifts in healthcare coverage.

Clouds of different colors: A prospective look at head and neck surgical resident call experience.

Graduate medical education programs typically set up call under the assumption that residents will have similar experiences. The terms black cloud and white cloud have frequently been used to describe residents with more difficult (black) or less difficult (white) call experiences. This study followed residents in the department of head and neck surgery during call to determine whether certain residents have a significantly different call experience than the norm. It is a prospective observational study con...


The reading frame rule suggests that Duchenne muscular dystrophy (DMD) results from DMD mutations causing an out-of-frame transcript, whereas the milder Becker muscular dystrophy results from mutations causing an in-frame transcript. However, predicted nonsense mutations may instead result in altered splicing and in-frame transcripts.

Trends in Economic Homogamy: Changes in Assortative Mating or the Division of Labor in Marriage?

The growing economic resemblance of spouses has contributed to rising inequality by increasing the number of couples in which there are two high- or two low-earning partners. The dominant explanation for this trend is increased assortative mating. Previous research has primarily relied on cross-sectional data and thus has been unable to disentangle changes in assortative mating from changes in the division of spouses' paid labor-a potentially key mechanism given the dramatic rise in wives' labor supply. We ...

Differential expression between "DSP-only" and DSP-PP523 transcripts in rat molar teeth.

To compare the expression patterns of two multiple transcripts derived from DSP-PP gene during tooth development. One is DSP-only transcript (i.e. does not encode PP) and the other is DSP-PP523 transcript, a main DSP-PP transcript.

Incidence, clinicopathologic features, and fusion transcript landscape of translocation renal cell carcinomas.

The recent article entitled "Incidence, clinicopathologic features, and fusion transcript landscape of translocation renal cell carcinomas" by Marion Classe and colleagues has been accepted in January 2017 by Histopathology(1) . The authors aimed to describe the landscape of fusion transcript in a large single institution series of interphase fluorescence in situ hybridization (FISH) confirmed translocation renal cell carcinomas (RCCs). They also identified two new fusion partners, GRIPAP1 and MED15, in Xp1...

Algorithmic Advances and Applications from RECOMB 2017.

This Cell Systems Call features invited summaries of 32 of the 38 papers accepted for presentation in the "regular track" at the 2017 Research in Computational Molecular Biology conference. The editors have categorized the summaries into cancer genomics, genetics, mass spectrometry, metagenomics, network analysis, phylogenetics, sequence annotation, sequence informatics, single-cell data analysis, and structural biology.

BCR-ABL1 transcript types showed distinct laboratory characteristics in patients with chronic myeloid leukemia.

In chronic myeloid leukemia (CML) two main types of messenger RNA (e14a2 and e13a2) can be produced by BCR-ABL1 gene rearrangement. Due to conflicting results, the clinical value of these transcripts remains controversial. The aim of this study was to identify associations of e14a2 and e13a2 transcripts with laboratory variables and also the response to treatment. This study included 203 adult patients with CML treated with Imatinib as first-line drug in a reference hematology center in Northeast Brazil. Cl...

An emergency call system for patients in locked-in state using an SSVEP-based brain switch.

Patients in a locked-in state (LIS) due to severe neurological disorders such as amyotrophic lateral sclerosis (ALS) require seamless emergency care by their caregivers or guardians. However, it is a difficult job for the guardians to continuously monitor the patients' state, especially when direct communication is not possible. In the present study, we developed an emergency call system for such patients using a steady-state visual evoked potential (SSVEP)-based brain switch. Although there have been previ...

Identification and expression analysis of alternatively spliced new transcript isoform of Bax gene in mouse.

Bax, a pro-apoptotic member of Bcl-2 family regulates apoptosis through homodimerization/heterodimerization with Bcl-2. Bax-α is the only product of the Bax gene that has been extensively studied. Bax-α exists in inactive form and several conformational changes are required during apoptosis to activate it. Here, we have identified a novel transcript variant of Bax gene in mouse which contains alternatively spliced new first exon that is different from the first exon of previously reported transcript. Conc...

Transcriptional accuracy modeling suggests two-step proofreading by RNA polymerase.

We suggest a novel two-step proofreading mechanism with two sequential rounds of proofreading selection in mRNA transcription. It is based on the previous experimental observations that the proofreading RNA polymerase cleaves off transcript fragments of at least 2 nt and that transcript elongation after a nucleotide misincorporation is anomalously slow. Taking these results into account, we extend the description of the accuracy of template guided nucleotide selection beyond previous models of RNA polymeras...

Note From the Editor-in-Chief: Who Wants to Exclude Older LGBT Persons From Public Health Surveillance?

It is sobering to publish Sell's call for every federal survey to include questions about sexual orientation and gender identity precisely when the Trump Administration excludes such questions from the proposed 2017 National Survey of Older Americans Act Participants (NSOAAP) conducted by the Administration for Community Living (ACL) in the Department of Health and Human Services. In particular, NSOAAP question DE1a, introduced in 2014, asked "Which of the following best represents how you think of yourself...

Official Call: 2017 Annual Business Meeting of the American Osteopathic Association.

Improving the Patient Experience: Call Light Intervention Bundle.

Delays in call light response are a significant patient quality and safety concern. Research on call light interventions and patient outcomes has focused exclusively on adult inpatients. This project examined the impact of increasing staff awareness and workflow redesign to improve the pediatric patient experience and outcomes based on timely response.

Oyster toadfish (Opsanus tau) boatwhistle call detection and patterns within a large-scale oyster restoration site.

During May 2015, passive acoustic recorders were deployed at eight subtidal oyster reefs within Harris Creek Oyster Sanctuary in Chesapeake Bay, Maryland USA. These sites were selected to represent both restored and unrestored habitats having a range of oyster densities. Throughout the survey, the soundscape within Harris Creek was dominated by the boatwhistle calls of the oyster toadfish, Opsanus tau. A novel, multi-kernel spectral correlation approach was developed to automatically detect these boatwhistl...

A lncRNA-H19 transcript from secondary hair follicle of Liaoning cashmere goat: Identification, regulatory network and expression regulated potentially by its promoter methylation.

The H19 transcript (imprinted maternally expressed transcript) is well-known as long noncoding RNA (lncRNA), and it is thought to be associated with the inductive capacity of dermal papilla cells for hair-follicle reconstruction. In this study, we isolated and characterized a lncRNA-H19 transcript from the secondary hair follicle of Liaoning cashmere goat. Also, we investigated its transcriptional pattern and methylation status of H19 gene in secondary hair follicle of this breed during different stages of ...

Transcript-level expression control of plant NLR genes.

Plant NLR genes encode sensitive immune receptors that can mediate specific recognition of pathogen avirulence effectors and activate a strong defense response termed effector-triggered immunity. The expression of NLRs requires strict regulation, as their ability to trigger immunity is dependent on their dose and overexpression of NLRs results in autoimmunity and massive fitness costs. An elaborate interplay of different mechanisms controlling NLR transcript levels allows plants to maximize their defense ca...

Bayesian estimation of differential transcript usage from RNA-seq data.

Next generation sequencing allows the identification of genes consisting of differentially expressed transcripts, a term which usually refers to changes in the overall expression level. A specific type of differential expression is differential transcript usage (DTU) and targets changes in the relative within gene expression of a transcript. The contribution of this paper is to: (a) extend the use of cjBitSeq to the DTU context, a previously introduced Bayesian model which is originally designed for identif...

ChimeRScope: a novel alignment-free algorithm for fusion transcript prediction using paired-end RNA-Seq data.

The RNA-Seq technology has revolutionized transcriptome characterization not only by accurately quantifying gene expression, but also by the identification of novel transcripts like chimeric fusion transcripts. The 'fusion' or 'chimeric' transcripts have improved the diagnosis and prognosis of several tumors, and have led to the development of novel therapeutic regimen. The fusion transcript detection is currently accomplished by several software packages, primarily relying on sequence alignment algorithms....

Auditory fatigue among call dispatchers working with headsets.

To determine whether call center dispatchers wearing headsets are subject to auditory fatigue at the end of a work shift.

The impact of delayed rapid response call activation on patient outcomes.

To investigate the impact of delay in rapid response call (RRC) activation on Hospital mortality.

Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues.

Most human genes generate multiple transcript isoforms. The differential expression of these isoforms can help specify cell types. Diverse transcript isoforms arise from the use of alternative transcription start sites, polyadenylation sites and splice sites; however, the relative contribution of these processes to isoform diversity in normal human physiology is unclear. To address this question, we investigated cell type-dependent differences in exon usage of over 18 000 protein-coding genes in 23 cell typ...

Effects of traffic noise on the calling behavior of two Neotropical hylid frogs.

Anthropogenic disturbance has been pointed to as one of the major causes of the world´s biodiversity crisis. Among them, noise pollution is a potential underestimated threat, projected to increase in the next decades accompanying urban expansion. Rising levels of noise pollution may result in negative impacts on species highly dependent on acoustic communication. Amphibians have long served as model organisms for investigating animal acoustic communication because their reproduction depends on transmitting...

How the environment shapes animal signals: a test of the Acoustic Adaptation Hypothesis in frogs.

Long distance acoustic signals are widely used in animal communication systems and, in many cases, essential for reproduction. The Acoustic Adaptation Hypothesis (AAH) implies that acoustic signals should be selected for further transmission and better content integrity under the acoustic constraints of the habitat in which they are produced. In the present study, we test predictions derived from the AAH in frogs. Specifically, we focus on the difference between torrent frogs and frogs calling in less noisy...

Multi-platform Analysis Reveals a Complex Transcriptome Architecture of a Circovirus.

In this study, we used Pacific Biosciences RS II long-read and Illumina HiScanSQ short-read sequencing technologies for the characterization of porcine circovirus type 1 (PCV-1) transcripts. Our aim was to identify novel RNA molecules and transcript isoforms, as well as to determine the exact 5'- and 3'-end sequences of previously described transcripts with single base-pair accuracy. We discovered a novel 3'-UTR length isoform of the Cap transcript, and a non-spliced Cap transcript variant. Additionally, ou...

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