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Medicure Files Patent Infringement Action PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Medicure Files Patent Infringement Action articles that have been published worldwide.
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More than ever, technical inventions are the symbol of our society's advance. Patents guarantee their creators protection against infringement. For an invention being patentable, its novelty and inventiveness have to be assessed. Therefore, a search for published work that describes similar inventions to a given patent application needs to be performed. Currently, this so-called search for prior art is executed with semi-automatically composed keyword queries, which is not only time consuming, but also pron...
Patents are widely used to protect intellectual property and a measure of innovation output. Each year, the USPTO grants over 150,000 patents to individuals and companies all over the world. In fact, there were more than 280,000 patent grants issued in the US in 2015. However, accessing, searching and analyzing those patents is often still cumbersome and inefficient. To overcome those problems, Google indexes patents and converts them to Extensible Markup Language (XML) files using Optical Character Recogni...
This paper assesses the extent to which patent renewal data is associated with government funding in a university context by focusing on the relationship between the funded patentees and renewal decisions of their patents. The aim of this paper is to show whether receiving funding from government contributes to high-value patents as measured by the patent renewal decisions made by their owners. Our observations of academic nanotechnology patents in Canada discovered a positive relationship between funded re...
If a target stimulus is presented together with a response irrelevant distractor stimulus, both stimuli can be encoded together with the response in an event file [see Hommel (Trends Cogn Sci 8:494-500, 2004)]. The repetition of the distractor can retrieve the encoded response. This kind of distractor-based retrieval is an important mechanism in action control. In the present experiment, we investigate whether and how distractor-based retrieval of event files is influenced by encoding specificity-a retrieva...
Yi-Shen-Hua-Shi (YSHS) granule is a modern Chinese patent drug for treating chronic glomerulonephritis (CGN). It is derived from a traditional Chinese medicine formula Sheng-Yang-Yi-Wei decoction that is used to treat CGN in ancient China. Pharmacological activities of YSHS granule have not been reported. In this work, we investigated the anti-CGN effects and TGFβ signaling-related mechanism of action of this herbal drug.
The reporting quality of patent landscapes is inadequate. The Reporting Items for Patent Landscapes (RIPL) checklist can improve reporting quality.
The distortion/interaction-activation strain model (D/I-ASM), a fragment analysis method, is applied to study the structure-reactivity relationship in reactions. The application of D/I-ASM involves the generation of input files for points along a reaction profile, submission of input files to a quantum software package, processing of parameters from the resulting output files and generation of graphical plots. The ExcelAutomat tool (Laloo et al., J. Comput. Aided Mol. Des. 2017, 31, 667) provides a framewor...
Linkage disequilibrium (LD) decay is of great interest in population genetic studies. However, no tool is available now to do LD decay analysis from variant call format (VCF) files directly. In addition, generation of pair-wise LD measurements for whole genome SNPs usually resulting in large storage wasting files.
The aim of the present study was to compare the effect of exposure to sodium hypochlorite (NaOCl) and ethylenediaminetetraacetic acid (EDTA) on the surface topography and roughness of HyFlex controlled memory (CM) and HyFlex electrical discharge machining (EDM) using atomic force microscopy (AFM). Twenty HyFlex EDM (25/.08) and 20 HyFlex CM (25/.06) files were divided into five groups (n = 4). One group served as a negative control group. The files in the other groups were exposed to 5.25% NaOCl and 17%...
The aim of the present study was to investigate the impact of ambient temperature on the life span of nickel-titanium (NiTi) files.
Patent application trends were investigated for induced pluripotent stem cell (iPSC) technologies, particularly disease-specific cell technologies related to iPSCs, in the U.S., Japanese, and European applications during 2017. The number of patent applications for iPSC technologies was 1516 in the United States, 895 in Japan, and 420 in Europe, with 5% of applications for disease-specific cell technologies. In contrast, the percentages of patent applications for iPSC preparation and differentiation technolo...
Nigerian policymakers are debating task-shifting injectable contraceptive services to Patent and Proprietary Medicine Vendors (PPMVs).
With federal mandates and incentives since the turn of this decade, electronic health records (EHR) have been widely adopted and used for clinical care. Over the last several years, we have seen both positive and negative perspectives on its use. Using an analysis of log files of EHR use, we investigated the nature of EHR use and their effect on an emergency department's (ED) throughput and efficiency.
Big data is characterised not only by the size of data files, but also by the diversity of data sources and continuity in data collection. Technological developments make it possible to store and analyse ever larger and more complex data files. Unlike more conventional research data, big data are often collected without explicit research questions in mind, and analytical techniques are used to find patterns in the data or to generate hypotheses. Examples of big data in medical research are the large data fi...
The current treatment approach in patent ductus arteriosus suggests the identification of high-risk infants that may benefit the most from treatment. Small for gestational age infants are a high-risk population in which the treatment approach to the patent ductus arteriosus and outcomes have not been described.
Patent ductus arteriosus (PDA) is the most common cardiovascular problem of prematurity. Our objective was to examine the effect of postmenstrual age (PMA) on response to medical PDA treatment.
We report a case of a 75-year-old woman with residual shunt of patent ductus arteriosus after initial surgical repair. She was successfully treated by thoracic aortic stent graft and residual shunt disappeared. Re-surgical repair for residual shunt of patent ductus arteriosus is very invasive and challenging procedure. Also endo-vascular repair using coil or an occluding device can be problematic because of anatomical change due to initial surgical repair. Thoracic aortic stent graft, as a re-intervention p...
This review explores the recent divergence in international patent law relating to the patenting of genes and related subject matter. This divergence stems primarily from decisions of the highest courts in the United States and Australia on the eligibility of patent claims relating to the BRCA gene sequences. Patent offices, courts, and policy makers have struggled for many years to clearly articulate the bounds of patent claims on isolated and synthetic DNA and related products and processes, including met...
We aimed to analyze whether patent foramen ovale (PFO) closure reduces the risk of stroke, assessing also some safety outcomes after the publication of a new trial.
To evaluate the effectiveness of drugs used to constrict patent ductus arteriosus (PDA) in newborns
A widely known alternative for reading and exchanging digital files is the PDF file, by Adobe. This type of file has become the most used for the electronic exchange of files. It is platform-independent, suitable for the exchange of medical data in electronic academic publication. PDF can support additional resources such image, media, even, three-dimensional surface mesh models. A three-dimensional model of the base of the skull is generated from computed tomography images to provide an overview of the PDF...
In commercial research and development projects, public disclosure of new chemical compounds often takes place in patents. Only a small proportion of these compounds are published in journals, usually a few years after the patent. Patent authorities make available the patents but do not provide systematic continuous chemical annotations. Content databases such as Elsevier's Reaxys provide such services mostly based on manual excerptions, which are time-consuming and costly. Automatic text-mining approaches ...
Recent randomized control trials (RCTs) have suggested benefit with transcatheter patent foramen ovale (PFO) closure plus antiplatelet therapy over medical treatment alone for secondary stroke prevention.
Patent ductus arteriosus (PDA) is prevalent in premature newborns and has been linked to the development of bronchopulmonary dysplasia (BPD), a serious pulmonary complication of premature birth. Although a causal relationship has not been proven, the link is greatest among infants born at lower gestational age who are treated with mechanical ventilation in the presence of a large ductal shunt. Despite strong association in epidemiological studies, treatment of a patent ductus arteriosus has not been shown t...
To evaluate the safety and feasibility of patent blue (PB) as the vital dye in Descemet membrane endothelial keratoplasty (DMEK).