PubMed Journals Articles About "Merkel Tries Bridge Climate Coalition Talks Heat" RSS

08:58 EDT 25th September 2018 | BioPortfolio

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Showing "Merkel tries bridge climate coalition talks heat" PubMed Articles 1–25 of 3,200+

Effects of climate change-related heat stress on labor productivity in South Korea.

This study assessed the potential impact of heat stress on labor productivity in South Korea; as such, stress is expected to increase due to climate change. To quantify the future loss of labor productivity, we used the relationship between the wet-bulb globe temperature and work-rest cycles with representative concentration pathways (RCPs) 4.5 and 8.5 as the climate change scenarios. If only climate factors are considered, then future labor productivity is expected to decline in most regions from the middl...

Air-quality-related health impacts from climate change and from adaptation of cooling demand for buildings in the eastern United States: An interdisciplinary modeling study.

Climate change negatively impacts human health through heat stress and exposure to worsened air pollution, amongst other pathways. Indoor use of air conditioning can be an effective strategy to reduce heat exposure. However, increased air conditioning use increases emissions of air pollutants from power plants, in turn worsening air quality and human health impacts. We used an interdisciplinary linked model system to quantify the impacts of heat-driven adaptation through building cooling demand on air-quali...

Cold-related mortality vs heat-related mortality in a changing climate: A case study in Vilnius (Lithuania).

Direct health effects of extreme temperatures are a significant environmental health problem in Lithuania, and could worsen further under climate change. This paper attempts to describe the change in environmental temperature conditions that the urban population of Vilnius could experience under climate change, and the effects such change could have on excess heat-related and cold-related mortality in two future periods within the 21st century.

Heat-related mortality trends under recent climate warming in Spain: A 36-year observational study.

Anthropogenic greenhouse gas emissions have increased summer temperatures in Spain by nearly one degree Celsius on average between 1980 and 2015. However, little is known about the extent to which the association between heat and human mortality has been modified. We here investigate whether the observed warming has been associated with an upward trend in excess mortality attributable to heat or, on the contrary, a decrease in the vulnerability to heat has contributed to a reduction of the mortality burden.

Escalating heat-stress mortality risk due to global warming in the Middle East and North Africa (MENA).

Climate change will substantially exacerbate extreme temperature and heatwaves. The impacts will be more intense across the Middle East and North Africa (MENA), a region mostly characterized by hot and arid climate, already intolerable for human beings in many parts. In this study, daily climate data from 17 fine-resolution Regional Climate Models (RCMs) are acquired to calculate wet-bulb temperature and investigate the mortality risk for people aged over 65 years caused by excessive heat stress across th...

Tarsal coalition in paediatric patients.

Tarsal coalition is due to failure of segmentation between two or more foot bones during embryological development at a site where the joint cleft fails to develop. Depending on the nature of the tissue connecting the bones, the abnormality is a syndesmosis, synchondrosis, or synostosis. Although the coalition exists at birth, synostosis usually develops only late during growth. Talo-calcaneal and calcaneo-navicular coalitions account for over 90% of all cases of tarsal coalition. The joint at the site of t...

Projecting future climate change impacts on heat-related mortality in large urban areas in China.

Global climate change is anticipated to raise overall temperatures and has the potential to increase future mortality attributable to heat. Urban areas are particularly vulnerable to heat because of high concentrations of susceptible people. As the world's largest developing country, China has experienced noticeable changes in climate, partially evidenced by frequent occurrence of extreme heat in urban areas, which could expose millions of residents to summer heat stress that may result in increased health ...

Efficacy and Safety of First-line Avelumab Treatment in Patients With Stage IV Metastatic Merkel Cell Carcinoma: A Preplanned Interim Analysis of a Clinical Trial.

Merkel cell carcinoma (MCC) is an aggressive skin cancer that is associated with poor survival outcomes in patients with distant metastatic disease. Results of part A of the JAVELIN Merkel 200 trial (avelumab in patients with Merkel cell carcinoma) showed that avelumab, an anti-programmed cell death ligand 1 (PD-L1) antibody, demonstrated efficacy in second-line or later treatment of patients with metastatic MCC (mMCC).

Impact of highway construction on land surface energy balance and local climate derived from LANDSAT satellite data.

Extensive construction of highways has a major impact on the landscape and its structure. They can also influence local climate and heat fluxes in the surrounding area. After the removal of vegetation due to highway construction, the amount of solar radiation energy used for plant evapotranspiration (latent heat flux) decreases, bringing about an increase in landscape surface temperature, changing the local climate and increasing surface run-off. In this study, we evaluated the impact of the D8 highway cons...

A Comparison of the Histopathologic Growth Patterns Between Non-Merkel Cell Small Round Blue Cell Tumors and Merkel Cell Carcinoma.

Merkel cell carcinoma (MCC) is a rare neuroendocrine cutaneous malignancy that shares cytologic, histopathologic, and immunohistochemical features with other small round blue cell (SRBC) tumors. Although the trabecular pattern is anecdotally associated with MCC, objective data are lacking.

Spatially explicit estimation of heat stress-related impacts of climate change on the milk production of dairy cows in the United Kingdom.

Dairy farming is one the most important sectors of United Kingdom (UK) agriculture. It faces major challenges due to climate change, which will have direct impacts on dairy cows as a result of heat stress. In the absence of adaptations, this could potentially lead to considerable milk loss. Using an 11-member climate projection ensemble, as well as an ensemble of 18 milk loss estimation methods, temporal changes in milk production of UK dairy cows were estimated for the 21st century at a 25 km resolution in...

Biopsy-Proven Metastatic Merkel Cell Carcinoma to the Orbit: Case Report and Review of Literature.

Merkel cell carcinoma is a rare neuroendocrine tumor of subspecialized dermal mechanoreceptors, associated with immunosuppression. The usual ophthalmic presentation is an eyelid lesion. The authors present a case of biopsy-proven orbital metastatic Merkel cell carcinoma in the absence of any eyelid lesion, in an immunosuppressed patient with a history of multiple cancers. There are to the authors' knowledge only 2 other case reports of presumed metastatic Merkel cell carcinoma to the orbit, though neither w...

Merkel Cell Polyomavirus is uncommon in New Zealand Merkel Cell Carcinomas.

Merkel Cell Carcinoma (MCC) is a rare skin tumour with an incidence of 0.88 per 100,000 people in New Zealand (NZ), one of the highest in the world and almost on par with close neighbours Australia . Current local diagnostic guidelines do not require analysis of the oncogenic Merkel Cell Polyoma Virus (MCPyV), therefore it has never been questioned whether the NZ-MCC MCPyV rate is similar to North American and European studies (40-89%) or indeed lower, as reported in Australian cohorts (18-24%) in which a U...

Seismic isolation retrofitting solution for an existing steel cable-stayed bridge.

This paper investigated the seismic retrofitting of an existing cable-stayed bridge through the use of a seismic isolation system. The bridge is situated in a high seismic zone. During the Saguenay earthquake 1988, one of the anchorage plates of the bridge supports failed. Herein, several configurations of seismic isolation system were considered to identify an appropriate solution for the seismic retrofitting of the bridge in both the longitudinal and transverse directions. A three-dimensional model of the...

The association between geographic location and incidence of Merkel cell carcinoma in comparison to melanoma: An international assessment.

The aim of this article was to provide worldwide, population-based incidence rates for Merkel cell carcinoma (MCC).

Poly ADP-ribose polymerase-1 as a potential therapeutic target in Merkel cell carcinoma.

Patients with metastatic Merkel cell carcinoma are treated similarly to small cell lung cancer (SCLC). Poly ADP-ribose polymerase-1 (PARP1) is overexpressed in SCLC and response to PARP inhibitors have been reported in patients with SCLC. Our study explores PARP as a therapeutic target in Merkel cell carcinoma.

Metabolic Reprogramming in Chloroplasts under Heat Stress in Plants.

Increases in ambient temperatures have been a severe threat to crop production in many countries around the world under climate change. Chloroplasts serve as metabolic centers and play a key role in physiological adaptive processes to heat stress. In addition to expressing heat shock proteins that protect proteins from heat-induced damage, metabolic reprogramming occurs during adaptive physiological processes in chloroplasts. Heat stress leads to inhibition of plant photosynthetic activity by damaging key c...

Assessing Vulnerability to Urban Heat: A Study of Disproportionate Heat Exposure and Access to Refuge by Socio-Demographic Status in Portland, Oregon.

Extreme urban heat is a powerful environmental stressor which poses a significant threat to human health and well-being. Exacerbated by the urban heat island phenomenon, heat events are expected to become more intense and frequent as climate change progresses, though we have limited understanding of the impact of such events on vulnerable populations at a neighborhood or census block group level. Focusing on the City of Portland, Oregon, this study aimed to determine which socio-demographic populations expe...

Physiological and agronomic performance of the coffee crop in the context of climate change and global warming: A review.

Coffee is one of the most important global crops and provides a livelihood to millions of people living in developing countries. Coffee species have been described as being highly sensitive to climate change, as largely deduced from modelling studies based on predictions of rising temperatures and changing rainfall patterns. Here, we discuss the physiological responses of the coffee tree in the context of present and ongoing climate changes, including drought, heat and light stresses, and interactions betwe...

Temporal and spatial change of climate resources and meteorological disasters under climate change during winter crop growing season in Guangdong Province, China.

Trend analysis method was applied to analyze the general variation characteristics of the climate resources and meteorological disasters of growing season of the winter planting in Guangdong before (1961-1996) and after climate warming (1997-2015). Percentile method was employed to determine thresholds for extreme cold and drought in major planting regions, and the characteristics of extreme disasters since climate warming were analyzed. The results showed that, by comparing 1997-2015 with 1961-1996, the he...

Clarifying the Connections Between Green Space, Urban Climate, and Heat-Related Mortality.

Endoscopic ultrasound diagnosis of Merkel cell carcinoma metastasizing to pancreas.

Merkel cell carcinoma (MCC) is a rare and aggressive primary neuroendocrine tumor of the skin, with a high propensity for local, regional and distant spread . However, distant metastasis of MCC to the pancreas are rarely seen. EUS-FNA is an effective tool in the evaluation and differential diagnosis of pancreatic mass lesions . Differentiating metastatic pancreatic tumors, especially Merkel cell carcinoma, from primary pancreatic tumor will influence clinical management and therapeutic strategies . This art...

Systematic review of sentinel lymph node biopsy in Merkel cell carcinoma of the head and neck.

Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neuroendocrine tumor arising on the head and neck in 40%-50% of patients. Between 20% and 40% will harbor subclinical nodal metastasis.

Heat exposure during outdoor activities in the US varies significantly by city, demography, and activity.

Environmental heat is a growing public health concern in cities. Urbanization and global climate change threaten to exacerbate heat as an already significant environmental cause of human morbidity and mortality. Despite increasing risk, very little is known regarding determinants of outdoor urban heat exposure. To provide additional evidence for building community and national-scale resilience to extreme heat, we assess how US outdoor urban heat exposure varies by city, demography, and activity. We estimate...

What is cold-related mortality? A multi-disciplinary perspective to inform climate change impact assessments.

There is a growing discussion regarding the mortality burdens of hot and cold weather and how the balance between these may alter as a result of climate change. Net effects of climate change are often presented, and in some settings these may suggest that reductions in cold-related mortality will outweigh increases in heat-related mortality. However, key to these discussions is that the magnitude of temperature-related mortality is wholly sensitive to the placement of the temperature threshold above or belo...

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