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PubMed Journals Articles About "Methodological Flaws Found Studies Reporting Adverse Effects Crops" RSS

20:19 EST 15th December 2018 | BioPortfolio

Methodological Flaws Found Studies Reporting Adverse Effects Crops PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Methodological Flaws Found Studies Reporting Adverse Effects Crops articles that have been published worldwide.

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Showing "Methodological Flaws Found Studies Reporting Adverse Effects Crops" PubMed Articles 1–25 of 59,000+

Antidepressants-related cardiovascular adverse events using the adverse event reporting system.

The aim of this study was to evaluate clinical manifestations and the age and sex distribution of cardiovascular adverse events (CVAEs) related to antidepressants. The FDA Adverse Event Reporting System (FAERS) and Korea Adverse Event Reporting System (KAERS) database records on patients prescribed antidepressants were used. The frequency of CVAEs was compared between adults (19-64 years) and an older (age ≥ 65 years) group. In total, 75,608 CVAEs from 43,824 patients and 325 CVAEs from 313 patients i...


Cement plant emissions and health effects in the general population: a systematic review.

Adverse health effects of cement plant exposure have been found in occupational contexts but are less defined for the general population living near plants. We aimed to summarize the evidence on the health effects of people exposed to ambient air pollution by cement plants. A systematic review using Embase, PubMed and Web of Science was performed. We included only non-occupational studies with a comparison group that focused on adverse health outcomes and biomarkers of internal dose or subclinical effect as...

Quality of reporting web-based and non-web-based survey studies: What authors, reviewers and consumers should consider.

Several influential aspects of survey research have been under-investigated and there is a lack of guidance on reporting survey studies, especially web-based projects. In this review, we aim to investigate the reporting practices and quality of both web- and non-web-based survey studies to enhance the quality of reporting medical evidence that is derived from survey studies and to maximize the efficiency of its consumption.


Review of animal studies on the cardiovascular effects of caffeine.

To address the safety of caffeine levels in energy drinks, we previously conducted a detailed evaluation of epidemiology studies in humans consuming coffee/caffeine, in which we assessed multiple health effects (unpublished). To further evaluate the effects of caffeine on the cardiovascular system, we turned to animal studies, which often use pure caffeine (not coffee), frequently at higher doses than those typical of human exposure. We identified key scientific studies and reviews in which effects of coffe...

The Psychiatry Morbidity and Mortality Incident Reporting Tool Increases Psychiatrist Participation in Reporting Adverse Events.

Although the reporting of adverse events (AEs) is widely thought to be a key first step to improving patient safety in hospital systems, underreporting remains a common problem, particularly among physicians. We aimed to increase the number of safety reports filed by psychiatrists in our hospital system.

Pharmacoeconomics Evaluations of Oral Anticancer Agents: Systematic Review of Characteristics, Methodological Trends, and Reporting Quality.

To review literature characteristics, describe methodological trends, and assess the reporting quality of the economic evaluations of oral anticancer drugs (OACDs).

Increasing the reliability and reproducibility of aquatic ecotoxicology: Learn lessons from aquaculture research.

Regulatory ecotoxicology highly relies on aquatic toxicity studies carried out under controlled conditions. Researchers recently expressed increasing concern about their possible lack of repeatability/reproducibility in many cases. Poor experimental designs, inappropriate statistics and lack of accurate reporting are often pointed out. However, I believe that there is also insufficient attention paid to the various experimental conditions under which fish studies are conducted. These conditions encompass nu...

Adverse Drug Reaction Reporting in Institutions Across Six Chinese Provinces: A Cross-sectional Study.

Although China's adverse drug reaction (ADR) reporting and monitoring has developed rapidly, many challenges remain. This study assessed ADR monitoring and reporting in China and identified monitoring problems.

Patient Reporting of Adverse Drug Reactions (ADRs): Survey of Public Awareness and Predictors of Confidence to Report.

Many countries incorporate direct patient reporting of adverse drug reactions (ADRs) into their pharmacovigilance systems as patients provide a different insight into drug safety compared to health care professionals. This study aimed to examine public awareness about ADR reporting in Malaysia and patients' confidence in reporting ADRs.

Gene-environment interactions and colorectal cancer risk: an umbrella review of systematic reviews and meta-analyses of observational studies.

The cause of colorectal cancer (CRC) is multifactorial, involving both genetic variants and environmental risk factors. We systematically searched the MEDLINE, EMBASE, China National Knowledge Infrastructure (CNKI) and Wanfang databases from inception to December 2016, to identify systematic reviews and meta-analyses of observational studies that investigated gene-environment (G × E) interactions in CRC risk. Then, we critically evaluated the cumulative evidence for the G × E interactions using an...

Do Exercise Trials for Hypertension Adequately Report Interventions? A Reporting Quality Study.

Non-pharmacological treatment, including exercise, is an important therapy option for patients with hypertension. The study assessed the reporting quality of exercise-based interventions included in the latest meta-analysis on that topic in order to evaluate the transferability of findings into clinical practice. Reporting quality of 24 randomised controlled trials from a meta-analysis assessing blood pressure lowering effects of endurance training in 1,195 hypertensive patients was evaluated using TIDieR (...

Side effects of corticosteroids in patients with advanced cancer: a systematic review.

Corticosteroids are commonly used in palliative care settings, but are associated with several side effects. Although adverse events (AEs) are highly distressing for patients, few data are available from prospective studies to look at incidence or predictors of such harms. The aim of this study is to identify AE reporting among studies of patients with advanced cancer receiving corticosteroids for any reason.

Reporting Adverse Events in Plastic Surgery: A Systematic Review of Randomized Controlled Trials.

Accurate knowledge of adverse events is critical for evaluation of the safety and efficacy of interventions. Historically, adverse events in surgical trials have been poorly reported. The objective of this study was to systematically evaluate the reporting of adverse events in randomized controlled trials (RCTs) in the plastic surgery literature.

The neuropsychopharmacology of cannabis: a review of human imaging studies.

The laws governing cannabis are evolving worldwide and associated with changing patterns of use. The main psychoactive drug in cannabis is Δ-tetrahydrocannabinol (THC), a partial agonist at the endocannabinoid CB receptor. Acutely, cannabis and THC produce a range of effects on several neurocognitive and pharmacological systems. These include effects on executive, emotional, reward and memory processing via direct interactions with the endocannabinoid system and indirect effects on the glutamatergic, GABAe...

General discussion of data quality challenges in social media metrics: Extensive comparison of four major altmetric data aggregators.

The data collection and reporting approaches of four major altmetric data aggregators are studied. The main aim of this study is to understand how differences in social media tracking and data collection methodologies can have effects on the analytical use of altmetric data. For this purpose, discrepancies in the metrics across aggregators have been studied in order to understand how the methodological choices adopted by these aggregators can explain the discrepancies found. Our results show that different ...

A systematic review about costing methodology in robotic surgery: evidence for low quality in most of the studies.

The main objective of this review was to evaluate the methodological design in studies reporting resource use and costs related to robotic surgery in gynecology.

50 Years of the Radiation Exposure Information and Reporting System and Importance to the Million Person Study.

As the Radiation Exposure Information and Reporting System (REIRS) celebrates 50 years of existence, this is an appropriate time to reflect on the innovative and novel system and how it has shaped the study of occupational radiation exposure. It is also fitting to appreciate the vision and initiative of the individuals who recognized the future value of the collection and analysis of this information to better inform regulations, policies, and epidemiologic studies, and thus contribute to the protection of ...

Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): An Abridged Explanation and Elaboration.

The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) were developed to address widespread deficiencies in the reporting of such studies. The REMARK checklist consists of 20 items to report for published tumor marker prognostic studies. A detailed paper was published explaining the rationale behind checklist items, providing positive examples and giving empirical evidence of the quality of reporting. REMARK provides a comprehensive overview to educate on good reporting and provide a val...

Reporting of adverse drug reactions in India: A review of the current scenario, obstacles and possible solutions.

Pharmacovigilance is a practice aimed to monitor drug safety in real life conditions and capture adverse drug events during the post marketing phase of drug's life cycle. But under reporting of adverse reactions is a major cause of concern and a threat to the pharmacovigilance systems. The present article looks into the major obstacles affecting the spontaneous reporting of adverse drug reactions (ADRs) in India and the possible solutions. As per available scientific literature, the major impediments to ADR...

Intervention integrity in mindfulness-based research: strengthening a key aspect of methodological rigor.

To ensure methodological rigour, research on Mindfulness-Based Programs (MBPs) should include systems for assessing and reporting the integrity of the intervention. The critical variable of the quality of the teaching and the degree of adherence to the curriculum are likely to influence research outcomes and their interpretation. Currently, three tools for assessing intervention integrity in the MBP field have been developed, but they need further research and development. Research going forward needs to in...

Three-Component Mixture Model-Based Adverse Drug Event Signal Detection for the Adverse Event Reporting System.

The US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) is an important source for detecting adverse drug event (ADE) signals. In this article, we propose a three-component mixture model (3CMM) for FAERS signal detection. In 3CMM, a drug-ADE pair is assumed to have either a zero relative risk (RR), or a background RR (mean RR = 1), or an increased RR (mean RR >1). By clearly defining the second component (mean RR = 1) as the null distribution, 3CMM estimates local false disc...

Methodological quality assessment of network meta-analysis of drug interventions: implications from a systematic review.

We aimed to determine the methodological quality of network meta-analyses (NMAs) and their compliance with reporting guidelines.

Methodological Challenges of Prevention Reporting - More to it Than Just Evidence Reporting!

The German Prevention Act came into force in 2015 with the aim of strengthening prevention of disease and health promotion, focussing on settings-based approaches. An established field of public health action is thus strengthened and expanded by a set of rules that has largely come into force as a social security law. The implementation of legislation is to be accompanied by the establishment of a prevention reporting system.

Community dynamics can modify the direction of simulated warming effects on crop yield.

Climate change affects agriculture through a range of direct and indirect pathways. These include direct changes to impacts of pests and diseases on crops and indirect effects produced by interactions between organisms. It remains unclear whether the net effects of these biotic influences will be beneficial or detrimental to crop yield because few studies consider multiple interactions within communities and the net effects of these on community structure and yield. In this study, we created two experimenta...

Formononetin and biochanin A protects against ritonavir induced hepatotoxicity via modulation of NfκB/pAkt signaling molecules.

Ritonavir (RIT) is a human immune deficiency virus (HIV) protease inhibitor (PI) active against HIV-1 and HIV-2. Among various adverse effects of PIs, hepatotoxicity is a very common adverse reaction of RIT which is concentration dependent. Red clover isoflavones are found to possess anti-inflammatory, antioxidant and anti-apoptosis activity. Furthermore, recent studies have demonstrated that these isoflavones can be used to alleviate the side-effects of drugs. Hence, the present study was inquested to asce...


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