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PubMed Journals Articles About "Mutant Mosquitoes Make Insecticide Resistance Monitoring Controlling Zika" RSS

05:07 EST 17th December 2018 | BioPortfolio

Mutant Mosquitoes Make Insecticide Resistance Monitoring Controlling Zika PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Mutant Mosquitoes Make Insecticide Resistance Monitoring Controlling Zika articles that have been published worldwide.

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Showing "Mutant mosquitoes make insecticide resistance monitoring controlling Zika" PubMed Articles 1–25 of 16,000+

G119S ace-1 mutation conferring insecticide resistance detected in the Culex pipiens complex in Morocco.

Arboviruses are controlled through insecticide control of their mosquito vector. However, inconsiderate use of insecticides often results in the selection of resistance in treated populations, so that monitoring is required to optimize their usage. Here, Culex pipiens (West Nile and Rift Valley Fever virus vector) specimens were collected from four Moroccan cities. Levels of susceptibility to the organophosphate (OP) insecticide malathion were assessed using WHO-recommended bioassays. Individual mosquitoes ...


Multiple insecticide resistance mechanisms in primary dengue vector, Aedes aegypti (Linn.) from dengue endemic districts of sub-Himalayan West Bengal, India.

Mosquitoes belonging to genus Aedes are the prime vectors of several arboviral diseases such as Dengue, Zika and Chikungunya worldwide. Every year numerous cases of dengue infections occur throughout the world, proper control of which depends on efficient vector control. However the onset of insecticide resistance has resulted in failure of vector control approaches.

The Insecticide Resistance Allele kdr-his has a Fitness Cost in the Absence of Insecticide Exposure.

House flies, Musca domestica L. (Diptera: Muscidae), are major pests at animal production facilities. Insecticides, particularly pyrethroids, have been used for control of house fly populations for more than 30 yr, but the evolution of resistance will likely jeopardize fly control efforts. A major mechanism of pyrethroid resistance in the house fly is target site insensitivity (due to mutations in the Voltage-sensitive sodium channel [Vssc]). Based on a survey of house fly populations in 2007 and 2008, the ...


Transgenic Metarhizium pingshaense synergistically ameliorates pyrethroid-resistance in wild-caught, malaria-vector mosquitoes.

Transgenic Metarhizium pingshaense expressing the spider neurotoxin Hybrid (Met-Hybrid) kill mosquitoes faster and at lower spore doses than wild-type strains. In this study, we demonstrate that this approach dovetails with the cornerstone of current malaria control: pyrethroid-insecticides, which are the cornerstone of current malaria control. We used World Health Organization (WHO) tubes, to compare the impact on insecticide resistance of Met-Hybrid with red fluorescent M. pingshaense (Met-RFP), used as a...

Non-covalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency.

Resistance development in insects significantly threatens the important benefits obtained by insecticide usage in vector control of disease-transmitting insects. Discovery of new chemical entities with insecticidal activity is highly desired in order to develop new insecticide candidates. Here, we present the design, synthesis, and biological evaluation of phenoxyacetamide-based inhibitors of the essential enzyme acetylcholinesterase 1 (AChE1). AChE1 is a validated insecticide target to control mosquito vec...

Insecticide-resistance mechanism of Plutella xylostella (L.) associated with amino acid substitutions in acetylcholinesterase-1: A molecular docking and molecular dynamics investigation.

Acetylcholinesterase-1 (AChE1) is a vital enzyme involved in neurotransmission and represents an attractive insecticide-target for organophosphates and carbamates in Plutella xylostella (Linneaus), an important pest of cruciferous crops worldwide. However, insecticide-resistance often occurs due to mutations, making many organophosphates and carbamates ineffective. In particular, A298S and G324A mutations in AChE1 significantly lower the binding affinity of insecticides. In the present study, the wild-type ...

Comparing the effectiveness of different strains of Wolbachia for controlling chikungunya, dengue fever, and zika.

Once Aedes aegypti and Aedes albopictus mosquitoes that spread Chikungunya virus, dengue virus, and Zika virus are infected with Wolbachia, they have reduced egg laying rates, reduced transmission abilities, and shorter lifespans. Since most infected mosquitoes are only infectious in the last few days of their lives, shortening a mosquito's lifespan by a day or two can greatly reduce their abilities to spread mosquito-borne viral diseases, such as Chikungunya, dengue fever, and Zika. We developed a mathemat...

Exploring insecticide resistance mechanisms in three major malaria vectors from Bangui in Central African Republic.

Malaria remains the main cause of mortality and morbidity in the Central African Republic. However, the main malaria vectors remain poorly characterised, preventing the design of suitable control strategies. Here, we characterised the patterns and mechanisms of insecticide resistance in three important vectors from Bangui. Mosquitoes were collected indoors, using electrical aspirators in July 2016 in two neighborhoods at Bangui. WHO bioassays performed, using F An. gambiae sensu lato (s.l.), revealed a high...

Mathematical model of Zika virus with vertical transmission.

Zika is a flavivirus transmitted to humans through either the bites of infected mosquitoes or sexual transmission. Zika has been linked to congenital anomalies such as microcephaly. In this paper, we analyze a new system of ordinary differential equations which incorporates human vertical transmission of Zika virus, the birth of babies with microcephaly and asymptomatically infected individuals. The Zika model is locally and globally asymptotically stable when the is less than unity. Our model shows that ...

Monitoring of Resistance in Field Populations of Scirtothrips dorsalis (Thysanoptera: Thripidae) and Diaphorina citri (Hemiptera: Liviidae) to Commonly Used Insecticides in Citrus in Central India.

Field populations of thrips (Scirtothrips dorsalis Hood) from citrus nurseries and psyllids (Diaphorina citri Kuwayama) from commercial citrus orchards of three districts in Maharashtra State in India were evaluated for levels of resistance to organophosphates (acephate, chlorpyrifos, quinalphos, and dimethoate), neonicotinoids (thiamethoxam, imidacloprid), abamectin and spinosad between 2012 and 2017. Leaf dip bioassays for thrips and shoot tip bioassay for nymph and adult psyllids were used to assess leve...

Comparative transcriptome analysis and RNA interference reveal CYP6A8 and SNPs related to pyrethroid resistance in Aedes albopictus.

Wide and improper application of pyrethroid insecticides for mosquito control has resulted in widespread resistance in Aedes albopictus mosquitoes, an important dengue vector. Therefore, understanding the molecular regulation of insecticide resistance is urgently needed to provide a basis for developing novel resistance diagnostic methods and vector control approaches. We investigated the transcriptional profiles of deltamethrin-resistant and -susceptible Ae. albopictus by performing paired-end sequencing f...

Effect of environmental variables and kdr resistance genotype on survival probability and infection rates in Anopheles gambiae (s.s.).

Environmental factors, especially ambient temperature and relative humidity affect both mosquitoes and malaria parasites. The early part of sporogony is most sensitive and is affected by high temperatures and temperature fluctuation immediately following ingestion of an infectious blood meal. The aim of this study was to explore whether environmental variables such as temperature, together with the presence of the kdr insecticide resistance mutations, have an impact on survival probability and infection rat...

Controlling vector-borne diseases by releasing modified mosquitoes.

Aedes mosquito-transmitted diseases, such as dengue, Zika and chikungunya, are becoming major global health emergencies while old threats, such as yellow fever, are re-emerging. Traditional control methods, which have focused on reducing mosquito populations through the application of insecticides or preventing breeding through removal of larval habitat, are largely ineffective, as evidenced by the increasing global disease burden. Here, we review novel mosquito population reduction and population modificat...

The antiviral piRNA response in mosquitoes?

There are several RNA interference (RNAi) pathways in insects. The small interfering RNA pathway is considered to be the main antiviral mechanism of the innate immune system; however, virus-specific P-element-induced Wimpy testis gene (PIWI)-interacting RNAs (vpiRNAs) have also been described, especially in mosquitoes. Understanding the antiviral potential of the RNAi pathways is important, given that many human and animal pathogens are transmitted by mosquitoes, such as Zika virus, dengue virus and chikung...

Managing Aedes aegypti populations in the first Zika transmission zones in the continental United States.

The African Zika virus swept across the Pacific, reaching the New World in 2014. In July, 2016, Miami-Dade County, Florida became the locus of the first mosquito-borne Zika transmission zones in the continental United States. Control efforts were guided by the Centers for Disease Control and Prevention, including aerial and truck sprays of adulticides and larvicides. To improve our understanding of how best to fight Zika transmission in an urban environment in the developed world, trap counts of adult Aedes...

The Aftermath of Zika: Need for Long-Term Monitoring of Exposed Children.

Pregnancy infections with Zika virus are associated with a spectrum of fetal brain injuries beyond microcephaly. Nonmicrocephalic children exposed to Zika virus in utero or early life should undergo neurodevelopmental testing to identify deficits and allow for early intervention. Additionally, long-term monitoring for higher order neurocognitive deficits should be implemented.

Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections.

Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions.

Bionomics and insecticide resistance of the arboviral vector Aedes albopictus in northern Lao PDR.

In the last four decades there has been a staggering increase in the geographical range of the arboviral vector Aedes albopictus (Skuse, 1894). This species is now found in every continent except Antarctica, increasing the distribution of arboviral diseases such as dengue and chikungunya. In Lao PDR dengue epidemics occur regularly, with cases of chikungunya also reported. As treatment methods for arboviral diseases is limited, the control of the vector mosquitoes are essential. There is a paucity of inform...

Insecticide-treated nets for preventing malaria.

A previous version of this Cochrane Review identified that insecticide-treated nets (ITNs) are effective at reducing child mortality, parasite prevalence, and uncomplicated and severe malaria episodes. Insecticide-treated nets have since become a core intervention for malaria control and have contributed greatly to the dramatic decline in disease incidence and malaria-related deaths seen since the turn of the millennium. However, this time period has also seen a rise in resistance to pyrethroids (the insect...

Autocidal Gravid Ovitrap Incorporation with Attractants for Control of Gravid and Host-Seeking Aedes aegypti (Diptera: Culicidae).

Aedes aegypti Linnaeus (Diptera: Culicidae) is a primary vector of multiple arboviruses including Zika, dengue, chikungunya, and yellow fever. After incorporating BG lure or BG lure + octenol, the CDC's Autocidal Gravid Ovitrap (AGO) was more effective at collecting and controlling host-seeking female Ae. aegypti than gravid female mosquitoes. The addition of octenol to the AGO did not increase the number of female mosquitoes captured by the AGO, compared with the AGO alone. The AGO baited with the BG lure ...

Diffusing Wild Type and Sterile Mosquitoes in an Optimal Control Setting.

This paper develops an optimal control framework to investigate the introduction of sterile type mosquitoes to reduce the overal moquito population. As is well known, mosquitoes are vectors of disease. For instance the WHO lists, among other diseases, Malaria, Dengue Fever, Rift Valley Fever, Yellow Fever, Chikungunya Fever and Zika. [http://www.who.int/mediacentre/factsheets/fs387/en/ ] The goal is to establish the existence of a solution given an optimal sterilization protocol as well as to develop the co...

Pyrethroid insecticides maintain repellent effect on knock-down resistant populations of Aedes aegypti mosquitoes.

Pyrethroid-treated clothing is commonly worn for protection against mosquitoes; pyrethroids are both insecticides and repellents. Pyrethroid resistance has become increasingly common in Aedes aegypti, the vector of dengue, Zika, and other arboviruses, but it is not clear whether resistance is associated with reductions in repellency. In order to determine whether long-lasting permethrin impregnated (LLPI) clothing is protective, we used Aedes aegypti from New Orleans, LA (pyrethroid-sensitive) and San Juan,...

Effect of Serratia AS1 (Enterobacteriaceae: Enterobacteriales) on the Fitness of Culex pipiens (Diptera: Culicidae) for Paratransgenic and RNAi Approaches.

The mosquito Culex pipiens is the primary vector of Rift Valley fever, West Nile, encephalitis, and Zika viruses, and periodic lymphatic filariasis. Developing insecticide resistance in mosquitoes demands the development of new approaches to fight these diseases. Paratransgenesis and RNAi approaches by using engineered bacteria have been shown to reduce mosquito vector competence. Serratia-AS1 is a bacterium found in mosquitoes and was genetically modified for expression of antimalaria effector molecules th...

Of mosquitoes and men: mitigating Zika risk via Men's family planning and male contraception.

Outbreaks of mosquito-borne viral illnesses commonly occur after storms. As storms are predicted to worsen in intensity and frequency, mosquito-borne viruses, including the Zika virus are expected to spread, and with devastating consequences. While the disease is self-limited, pregnant women who contract Zika can transmit the virus to their fetuses, causing neurodevelopmental abnormalities, including microcephaly. An overlooked vector of the Zika virus, however, is men whose semen can transmit the virus at ...

Disruption of the microbiota affects physiological and evolutionary aspects of insecticide resistance in the German cockroach, an important urban pest.

The German cockroach, Blatella germanica, is a common pest in urban environments and is among the most resilient insects in the world. The remarkable ability of the German cockroach to develop resistance when exposed to toxic insecticides is a prime example of adaptive evolution and makes control of this insect an ongoing struggle. Like many other organisms, the German cockroach is host to a diverse community of symbiotic microbes that play important roles in its physiology. In some insect species, there is...


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