PubMed Journals Articles About "Noblegen Announces Opening Second Round Financing Peterborough Based" RSS

14:25 EDT 19th June 2018 | BioPortfolio

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Showing "Noblegen Announces Opening Second Round Financing Peterborough Based" PubMed Articles 1–25 of 32,000+

Financing the Primary Care Behavioral Health Model.

The PCBH model of integrated care blends behavioral health professionals into the primary care team, thereby enhancing the scope of primary care and expanding the range of services provided to the patient. Despite promising evidence in support of the model and a growing number of advocates and practitioners of PCBH integration, current reimbursement policies are not always favorable. As the nation's healthcare system transitions to value-based payment models, new financing strategies are emerging which will...

"Pay for Success" Financing and Home-Based Multicomponent Childhood Asthma Interventions: Modeling Results From the Detroit Medicaid Population.

Policy Points: The Pay for Success (PFS) financing approach has potential for scaling the implementation of evidence-based prevention interventions in Medicaid populations, including a range of multicomponent interventions for childhood asthma that combine home environment risk mitigation with medical case management. Even though this type of intervention is efficacious and cost-saving among high-risk children with asthma, the main challenges for implementation in a PFS context include legal and regulatory ...

Health financing policies in Sub-Saharan Africa: government ownership or donors' influence? A scoping review of policymaking processes.

The rise on the international scene of advocacy for universal health coverage (UHC) was accompanied by the promotion of a variety of health financing policies. Major donors presented health insurance, user fee exemption, and results-based financing policies as relevant instruments for achieving UHC in Sub-Saharan Africa. The "donor-driven" push for policies aiming at UHC raises concerns about governments' effective buy-in of such policies. Because the latter has implications on the success of such policies,...

VA Announces Plan to Improve Worst-Performing Medical Centers.

A novel image-based system for risk stratification in patients with desmoplastic small round cell tumor.

Desmoplastic small round cell tumor (DSRCT) is an aggressive soft tissue sarcoma affecting children and young adults with 5-year overall survival (OS) of approximately 20%. Despite generally poor prognosis, long-term survival does occur. However, no evidence-based system exists to risk-stratify patients at diagnosis.

Carbon Emission Reduction with Capital Constraint under Greening Financing and Cost Sharing Contract.

Motivated by the industrial practices, this work explores the carbon emission reductions for the manufacturer, while taking into account the capital constraint and the cap-and-trade regulation. To alleviate the capital constraint, two contracts are analyzed: greening financing and cost sharing. We use the Stackelberg game to model four cases as follows: (1) in Case A1, the manufacturer has no greening financing and no cost sharing; (2) in Case A2, the manufacturer has greening financing, but no cost sharing...

How to do (or not to do) … a health financing incidence analysis.

Financing incidence analysis (FIA) assesses how the burden of health financing is distributed in relation to household ability to pay (ATP). In a progressive financing system, poorer households contribute a smaller proportion of their ATP to finance health services compared to richer households. A system is regressive when the poor contribute proportionately more. Equitable health financing is often associated with progressivity. To conduct a comprehensive FIA, detailed household survey data containing reli...

Estimation of jaw-opening forces in adults.

To estimate maximum jaw-opening forces in healthy participants of diverse ancestry and to estimate whether opening forces are associated with sex, age and anthropometric parameters such as height, weight and BMI.

Surgical Anatomy of the Round Window - Implications for Cochlear Implantation.

The round window is an important portal for the application of active hearing aids and cochlear implants. The anatomical and topographical knowledge about the round window region is a prerequisite for successful insertion for a cochlear implant electrode.

Purely Physisorption-based CO-Selective Gate-Opening in Microporous Organically Pillared Layered Silicates.

Separation of gas molecules with similar physical and chemical properties is challenging but nevertheless highly relevant for chemical processing. By introducing the elliptically shaped molecule, 1,4-Dimethly-1,4-diazabicyclo[2.2.2]octane, into the interlayer space of a layered silicate, a two-dimensional microporous network with narrow pore size distribution is generated (MOPS-5). The regular arrangement of the pillar molecules in MOPS-5 was confirmed by the occurrence of a 10-band related to a long-range ...

Anterior Bite Opening in Adulthood.

To study anterior bite opening of unknown cause presenting in adulthood regarding prevalence, symptoms of Temporomandibular Dysfunction (TMD) and possible causes of the bite opening.

Using a complex optical orbital-angular-momentum spectrum to measure object parameters.

Light beams can be characterized by their complex spatial profiles in both intensity and phase. Analogous to time signals, which can be decomposed into multiple orthogonal frequency functions, a light beam can also be decomposed into a set of spatial modes that are taken from an orthogonal basis. Such decomposition can potentially provide a tool for spatial spectrum analysis, which may enable stable, accurate, and robust extraction of physical object information that may not be readily achievable using trad...

Quantifying the Physical Response to a Contemporary Amateur Boxing Simulation.

Finlay, MJ, Greig, M, and Page, RM. Quantifying the physical response to a contemporary amateur boxing simulation. J Strength Cond Res 32(4): 1005-1012, 2018-This study examined the physical response to a contemporary boxing-specific exercise protocol (BSEP), based on notational analysis of amateur boxing. Nine male senior elite amateur boxers completed a 3 × 3-minute BSEP, with a 1-minute passive recovery period interspersing each round. Average (HRave) and peak (HRpeak) heart rates, average (V[Combining ...

Corn-Based Distillers' Grains in Diets for Feedlot Cattle are Associated with the Burden of Escherichia coli O157 in Feces.

Inclusion of distillers' grains (DGs) has been associated with increased prevalence of Escherichia coli O157:H7 in cattle housed in research settings. Our objective was to quantify the relationship between inclusion of DGs in commercial feedlot rations and the burden of E. coli O157. A convenience sample of 10 feedlots was enrolled based on DG use in finishing diets; 1 cohort included 5 feedlots in which DGs were greater than 15% of the dietary dry matter and the other cohort consisted of 5 feedlots at a co...

Disease-specific out-of-pocket and catastrophic health expenditure on hospitalization in India: Do Indian households face distress health financing?

Rising non-communicable diseases (NCDs) coupled with increasing injuries have resulted in a significant increase in health spending in India. While out-of-pocket expenditure remains the major source of health care financing in India (two-thirds of the total health spending), the financial burden varies enormously across diseases and by the economic well-being of the households. Though prior studies have examined the variation in disease pattern, little is known about the financial risk to the families by ty...

Context matters (but how and why?) A hypothesis-led literature review of performance based financing in fragile and conflict-affected health systems.

Performance-based financing (PBF) schemes have been expanding rapidly across low and middle income countries in the past decade, with considerable external financing from multilateral, bilateral and global health initiatives. Many of these countries have been fragile and conflict-affected (FCAS), but while the influence of context is acknowledged to be important to the operation of PBF, there has been little examination of how it affects adoption and implementation of PBF. This article lays out initial hypo...

Community-based mass treatment with azithromycin for the elimination of yaws in Ghana-Results of a pilot study.

The WHO yaws eradication strategy consists of one round of total community treatment (TCT) of single-dose azithromycin with coverage of > 90%.The efficacy of the strategy to reduce the levels on infection has been demonstrated previously in isolated island communities in the Pacific region. We aimed to determine the efficacy of a single round of TCT with azithromycin to achieve a decrease in yaws prevalence in communities that are endemic for yaws and surrounded by other yaws-endemic areas.

UHMS announces position statement on low-pressure, soft-sided hyperbaric chambers.

Rhabdomyosarcoma, Ewing Sarcoma, and Other Round Cell Sarcomas.

Several recent advances have been made in the diagnosis and therapy of malignant small round cell tumors that affect children, particularly in rhabdomyosarcoma, Ewing sarcoma, and other round cell sarcomas. These advances have provided new insights into the pathologic, histologic, and genomic characterization of specific tumor subtypes, which has led to the identification of novel therapeutic targets and improved stratification of risk. This has, in turn, led to improved efficacy in clinical trials of new d...

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency.

Despite its exciting potential, chemical induction of pluripotency (CIP) efficiency remains low and the mechanisms are poorly understood. We report the development of an efficient two-step serum- and replating-free CIP protocol and the associated chromatin accessibility dynamics (CAD) by assay for transposase-accessible chromatin (ATAC)-seq. CIP reorganizes the somatic genome to an intermediate state that is resolved under 2iL condition by re-closing previously opened loci prior to pluripotency acquisition...

Foundation for an Evidence Informed Algorithm for Treating Pelvic Floor Mesh Complications: A Review.

To address evidence gaps on the management of complications related to mesh in pelvic floor surgery, we created an evidence-based algorithm, including defining evidence gaps. We utilized the Delphi Method within a panel of surgeons treating mesh complications to define a treatment strategy. The first round provided a list of clinically based postulates that informed a review, which expanded postulates to recommendations, including grading of the quality of evidence. A second round informed the final algorit...

Methanol-Assisted Phthalimide Ring Opening: Concerted or Stepwise Mechanism?

The opening of the five-membered ring is the essential step for phthalimide and its derivatives to be used as the reactants in many chemical synthetic routes. Reportedly, such ring opening follows the concerted mechanism in methanol solvent, which, however, has an unreasonably high energy barrier (36.3 kcal molat the M06-2X/6-311++G(d,p) level of theory). By density functional theory calculations, we report that this ring opening prefers the alternatively stepwise mechanism. The stepwise mechanism has a muc...

Banking for health: the role of financial sector actors in investing in global health.

The world faces multiple health financing challenges as the global health burden evolves. Countries have set an ambitious health policy agenda for the next 15 years with prioritisation of universal health coverage under the Sustainable Development Goals. The scale of investment needed for equitable access to health services means global health is one of the key economic opportunities for decades to come. New financing partnerships with the private sector are vital. The aim of this study is to unlock additio...

All-round utilization of biomass derived all-solid-state asymmetric carbon-based supercapacitor.

All-round utilization of resources is proposed for maximizing environmental and economic benefits. Herein, the concept of all-round utilization on biomass derivations applying to carbon-based supercapacitors is demonstrated. Orange peel is used for all subassemblies of supercapacitor, including electrodes, separator and electrolyte. A monolithic porous carbon (OPHPC) is prepared by one-step carbonization of orange peel and another composite electrode is further synthesized by a simple hydrothermal process, ...

Power cavitation-guided blood-brain barrier opening with focused ultrasound and microbubbles.

Image-guided monitoring of microbubble-based focused ultrasound (FUS) therapies relies on the accurate localization of FUS-stimulated microbubble activity (i.e. acoustic cavitation). Passive cavitation imaging with ultrasound arrays can achieve this, but with insufficient spatial resolution. In this study, we address this limitation and perform high-resolution monitoring of acoustic cavitation-mediated blood-brain barrier (BBB) opening with a new technique called power cavitation imaging. By synchronizing t...

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