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21:23 EDT 3rd April 2020 | BioPortfolio

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Showing "Pele Depressed Reclusive Health Issues Says" PubMed Articles 1–25 of 21,000+

PELE-MSM: a Monte Carlo based protocol for the estimation of absolute binding free energies.

In this study, we present a fully automatic platform based on our Monte Carlo algorithms, the Protein Energy Landscape Exploration method (PELE), for the estimation of absolute protein-ligand binding free energies, one of the most significant challenges in computer aided drug design. Based on a ligand pathway approach, an initial short enhanced sampling simulation is performed to identify reasonable starting positions for more extended sampling. This stepwise approach allows for a significant faster converg...

Enhancing the care of children and young people with mental health issues.

Early intervention in children and young people with mental health issues is important to ensure that these issues do not persist into adulthood. However, while children and young people with mental health issues have traditionally been cared for in specialist facilities to ensure their safety, a lack of inpatient beds means that these patients are being admitted to children's wards in general hospitals. Children's nurses require education and training in mental health to provide optimal care for these chil...

Education, training, and experience in public health ethics and law within the UK public health workforce.

Public health ethics and law (PHEL) is a core professional competency for the public health workforce. However, few data are available describing the extent to which UK public health workforce members experience ethical and legal issues or have sufficient educational and/or training background to adequately deal with such issues.

A qualitative exploration of mental health service user and carer perspectives on safety issues in UK mental health services.

Service user and carer perspectives on safety issues in mental health services are not well known and may be important in preventing and reducing harm. The development of the Yorkshire Contributory Factors Framework-Mental Health (YCFF-MH) provides a broad structure within which to explore these perspectives.

Preoperative 5-aminolevulinic acid administration for brain tumor surgery is associated with an increase in postoperative liver enzymes: a retrospective cohort study.

Besides 5-aminolevulinic acid (5-ALA), liver enzyme elevation after brain tumor surgery can be caused by anesthesia and medications. In this retrospective study, we determined whether preoperative 5-ALA administration is associated with postoperative elevation of liver enzymes (PELE) in brain tumor patients and identified predictive factors for PELE in patients treated with 5-ALA.

What makes adolescents psychologically distressed? Life events as risk factors for depression and suicide.

Adolescence is a vulnerable period for psychological distress. This study aimed to comprehensively investigate the distribution of major stress-causing factors and their correlates in a large population of adolescents. A computerized self-report questionnaire was completed by 291,110 participating adolescents over a 4-year period using a cross-sectional study design. The questionnaire included items assessing demographic variables, major stressors, severity of perceived stress, and mental health outcomes su...

Interpersonal trauma and suicide attempts in low-income depressed mothers in home visiting.

Risk of suicide is a major concern for depressed mothers in the perinatal period. The strongest predictor of completing suicide is having made a previous attempt. Little is known about the clinical features of low-income, depressed mothers who have attempted suicide in contrast to those who have not.

Healthcare Clinician and Staff Perspectives on Facilitators and Barriers to Ideal Sexual Health Care to High-Risk Depressed Young Women: A Qualitative Study of Diverse Clinic Systems.

This study identified clinician and clinic staff perspectives on facilitators and barriers to providing sexual and reproductive health (SRH) care to depressed young women, a population at increased risk for adverse SRH outcomes.

The roles of repetitive negative thinking and perfectionism in explaining the relationship between sleep onset difficulties and depressed mood in adolescents.

The present study investigated the relationship between difficulty initiating sleep and depressed mood and whether it is mediated by repetitive negative thinking. A moderating role of perfectionism was also examined.

Common issues related to children's environmental health in the Asia-Pacific region.

This summary reports on the outcomes and common issues faced among the countries represented at the Asia-Pacific Regional Meeting on Children's Environmental Health, a meeting that was held at the Chulabhorn Research Institute in Bangkok, Thailand, and which focused on cross-cutting issues and commonalities among countries/regions, discussion of lessons learnt, exploring opportunities for policy-relevant research collaborations, and reviewing available educational tools to help translate research findings i...

Interdependence between health and peace: a call for a new paradigm.

Health and peace, and their relationships to disease/conflict/violence, are complex and multifaceted interrelated terms. Scholars have proposed a variety of definitions for health and peace. The conceptualizations of health and peace share many fundamental elements, including in their social, psychological (emotional and mental) and spiritual dimensions. We argue that health and peace are inter-dependent in a fundamental causal fashion. Health is always positively or negatively affected by conflict; peace c...

Migration Health: Highlights from Inaugural International Society of Travel Medicine (ISTM) Conference on Migration Health.

International migration is a global phenomenon that is growing in scope, complexity and impact. The inaugural International Society of Travel Medicine (ISTM) International Conference on Migration Health provided a forum to discuss scientific evidence on the broad issues relevant to migration health. This review summarises the key health issues, with a focus on infectious diseases, current effective strategies and future considerations presented at this forum and in the recent literature.

Physical Health Care in Mental Health Services: The Time for Action Is Now.

The Role of Academic Health Centers in Addressing Health Equity and Social Determinants of Health.

Elsewhere in this issue, Park and colleagues argue that academic health centers (AHCs) must partner with communities to address health disparities and social determinants of health (SDOH). Who is ultimately responsible for addressing them is in question. Countries that have been successful in improving the health of their populations have made these efforts a national priority by, among other things, ensuring universal health care coverage. To date, the United States has failed to adequately address these i...

Depressed fractures of the base of the middle phalanges of the fingers : Evaluation of a percutaneous, intramedullary surgical technique.

Depressed fractures of the base of the middle phalanges are problematic because of frequent subluxations and centrally depressed fragments. There are two minimally invasive procedures available: 1) the less known intramedullary padding technique according to Hintringer and 2) the widely used distraction fixator of Suzuki. This article describes the technique and outcome of these two procedures.

Valuing Health State: An EQ-5D-5L Value Set for Ethiopians.

There is a growing interest in health technology assessment and economic evaluations in developing countries such as Ethiopia. The objective of this study was to derive an EQ-5D-5L value set from the Ethiopian general population to facilitate cost utility analysis.

Exploring How People Affected by Methamphetamine Exchange Social Support Through Online Interactions on Facebook: Content Analysis.

Methamphetamine is an illicit and addictive psychostimulant that remains to be a significant cause of economic burden in Australia. Social media is increasingly being used by nongovernment organizations and health services to encourage the growth of social support networks among people with health-related issues. Several studies have investigated the utility of social media in providing social support to groups of people with health-related issues. However, limited research exists that explores how people w...

The Drug and Alcohol Clinical Advisory Service: A model of telephone-delivered addiction specialist support.

People with substance use problems frequently present to mainstream health services with a variety of health issues. However, many medical and allied health-care providers feel under-equipped to respond to this population. We describe the Drug and Alcohol Clinical Advisory Service (DACAS), an established 24/7 telephone-delivered model of addiction specialist consultation, and examine recent call data to identify drug use issues for which health practitioners seek support.

Evaluation of, a Canadian Mental Health Website Portal: Mixed Methods Assessment.

Many Canadians have mental health needs, and it can be challenging not knowing where to go for mental health information, services, and support. The website was created to facilitate and assist Canadians to (1) learn about mental health, (2) screen for common mental health issues, and (3) find mental health services and support.

Advancing pharmacist prescribing privileges: Is it time?

The rising cost of health care, impact of the aging population, physician shortages, and access to care issues have stressed the U.S. health care system. There is no single solution to combat the complexity of issues concerning the health care system; however, there are potential solutions, such as expanding the role of pharmacists, in efforts to alleviate some stress. Advancing the scope of pharmacy practice with the inclusion of autonomous prescribing authority may enhance access to health care if barrier...

The Price of Substitute Technologies.

Only a small share of new drugs is truly innovative; 85% to 90% of all new health technologies have little or no advantage over existing therapeutic alternatives. Health economic evaluations can be used to induce acceptable prices for new technologies through threshold pricing.

Revision of a depressed scar across a relaxed skin tension line by punch elevation, filler injection, and fractional CO₂ laser.

Revision of a depressed scar is more challenging because it does not follow the relaxed skin tension line (RSTL). Several measures have been suggested for revision of this type of scar, and they have a number of limitations, complications, advantages, and disadvantages. A 45-year-old woman presented with a depressed scar measuring approximately 45 × 2.5 mm across the chin area as a result of an accidental sharp trauma 17 years previously. She was subjected to several procedures to revise the scar, but none...

Gum health - who cares?

Much of the British population have poor gum health which can affect their daily lives and general health. Surprisingly, we don't often hear from the public whether they care about this situation. Is this a lack of interest or a lack of opportunity to be heard? In addition, gum health, like overall health, requires people to take care of themselves and to take ownership of their condition. Whose responsibility is it to promote this care? In this article, a BSP Patient Forum member (Barbara Sturgeon) and cli...

Whose story is it? Mental health consumer and carer views on carer participation in research.

Mental health carers contribute a unique set of perspectives and lived experiences to research; however, national research ethics guidelines do not specifically address the issues that affect informal carers as participants.

Two unresolved issues in community engagement for field trials of genetically modified mosquitoes.

There is an emerging consensus among scientists, ethicists, and public health officials that substantive and effective engagement with communities and the wider public is required prior to releasing genetically modified mosquitoes into the environment. While there is little disagreement about the need for community and public engagement prior to releasing genetically modified mosquitoes into the environment, two important issues have not been resolved, namely: defining the community and dealing with potenti...

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