PubMed Journals Articles About "Pharma Groups Deliver Mixed Performance" RSS

00:38 EST 17th January 2019 | BioPortfolio

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Showing "Pharma groups deliver mixed performance" PubMed Articles 1–25 of 21,000+

Pharma APMs: Can the Industry Learn To Play Well With Others?

The alternative payment model (APM) is a nontraditional financial arrangement that rewards health care providers who deliver cost-effective, high-quality care. Now we are facing the possibility that pharmaceutical manufacturers and insurers will embrace APMs as a payment mechanism in some situations.

Compound tribo-electrostatic separation for recycling mixed plastic waste.

To separate mixed plastic wastes into pure components can hugely elevate their reusable value and reduce the environmental risks. This study proposes a compound process to handle mixed plastics wastes. The study used mixed plastic granules of polypropylene (PP), acrylonitrile butadiene styrene (ABS), poly vinyl chloride (PVC), and polystyrene (PS) as the feeding material. Vibrating and cyclone tribo-chargers were used to find charge performance of different granules. In vibrating tribo-charger the biggest g...

CVS and the $100,000 QALY.

The PBM unit of the health giant CVS decided that any new drug exceeding $100,000 per quality-adjusted life year (QALY) may be excluded from the formularies that are maintained by its clients. Patient groups (with the backing of pharma) say that the measure is discriminatory.

Effects of kinesio taping on neuromuscular performance and pain of individuals affected by patellofemoral pain: A randomized controlled trial.

Patellofemoral pain (PFP) is one of the most frequent musculoskeletal dysfunctions in the knee and its treatment is controversial. This study analyzed the effects of Kinesio Taping (KT) immediately and 72 hours after its application on the electromyographic (EMG) activity of the vastus medialis oblique (VMO) muscle, on the isokinetic performance of the quadriceps femoris and on the pain of subjects with PFP. Fifty-four participants were divided into three groups and performed one of the following protocols...

Critical evaluation of linear regression models for cell-subtype specific methylation signal from mixed blood cell DNA.

Epigenome-wide association studies seek to identify DNA methylation sites associated with clinical outcomes. Difference in observed methylation between specific cell-subtypes is often of interest; however, available samples often comprise a mixture of cells. To date, cell-subtype estimates have been obtained from mixed-cell DNA data using linear regression models, but the accuracy of such estimates has not been critically assessed. We evaluated linear regression performance for cell-subtype specific methyla...

21 Century Citizen Pharma: The FDA & Patient-Focused Product Development.

Perpetual debate regarding the delicate balance between access and innovation and the protection of the public health and safety dominate discussions of the United States Food and Drug Administration ("FDA"). Established chiefly as a command and control federal administrative agency, iterative changes in legislation have shaped the FDA's activity in drug, biologic, and medical device regulation over the course of the last one hundred plus years. The most recent fundamental reframing of the agency's authorit...

Caesium-Incorporated Triple Cation Perovskites Deliver Fully Reversible and Stable Nanoscale Voltage Response.

Perovskite solar cells that incorporate small concentrations of Cs in their A-site have shown increased lifetime and improved device performance. Yet, the development of fully stable devices operating near the theoretical limit requires understanding how Cs influences perovskites' electrical properties at the nanoscale. Here, we determine how the chemical composition of three perovskites (MAPbBr3, MAPbI3, and Cs-mixed) affects their short- and long-term voltage stabilities, with

When Group Work Doesn't Work: Insights from Students.

Introducing group work in college science classrooms can lead to noticeable gains in student achievement, reasoning ability, and motivation. To realize these gains, students must all contribute. Strategies like assigning roles, group contracts, anonymous peer evaluations, and peer ratings all encourage student participation. In a class using these strategies, we conducted in-depth interviews to uncover student perceptions of group work in general and the utility of these support strategies. Students in both...

Racial And Ethnic Differences In The Attainment Of Behavioral Health Quality Measures In Medicare Advantage Plans.

As the Medicare population becomes more diverse and its demand for behavioral health care grows, a better understanding of racial/ethnic disparities in the quality of behavioral health care is crucial. Medicare Advantage (MA) plans are accountable through the public reporting of quality performance on measures, including the Healthcare Effectiveness Data and Information Set (HEDIS). We examined HEDIS data on eight MA behavioral health care quality measures, using mixed-effects logistic regressions to distin...

Mechanism and kinetics of catalytic ozonation for elimination of organic compounds with spinel-type CuAlO and its precursor.

CuAlO based mixed oxides were used as heterogeneous catalysts for ozone activation to degrade organics in aqueous solution. The solids were thoroughly characterized by SEM/EDS, N physisorption, XRD, FTIR, Pyridine-FTIR, TEM and XPS. We demonstrated that the solid precursor calcined at 300 °C exhibited the best catalytic ozonation activity with respect to CuAlO spinel phase obtained at higher temperatures. Such performance was attributed to the better textural properties and a higher density of active sit...

Effect of mixed surface terminations on the structural and electrochemical properties of two-dimensional TiCT and VCT MXenes multilayers.

MXenes, a family of layered transition metal carbides and nitrides, have shown great promise for use in emerging electrochemical energy storage devices, including batteries and supercapacitors. MXene surfaces are terminated by mixed -O, -F and -OH functional groups as a result of the chemical etching production process. These functional groups are known to be randomly distributed over the surfaces, with limited experimental control over their composition. There is considerable debate regarding the contribut...

Towards High Performance MOF - Microporous Polymer Mixed Matrix Membranes: Addressing Compatibility and Limiting Aging via Polymer Doping.

Membrane separation for gas purification is an energy-efficient and environment-friendly technology. However, the development of high performance membranes is still a great challenge. In principle, mixed matrix membranes (MMMs) have the potential to overcome current materials limitations, but in practice there is no straightforward method to match the properties of fillers and polymers (the main components of MMMs) in such a way that the final membrane performance reflects the high performance of the microp...

The impact of β-glucans on performance and response of broiler chickens during a coccidiosis challenge.

Coccidiosis is a costly parasitic disease to the poultry industry with multiple prevention methods being explored to control its impact. This study evaluated the feeding effects of β-glucans on performance and responses of chickens during a coccidiosis challenge. Cobb 500 male broilers (n = 1280) were assigned to 1 of 8 treatment groups (8 replicate pens; 20 birds/pen) in a 2 × 4 factorial arrangement, including non-infected and Eimeria-infected birds fed for 28 d a control diet, control + BG (150 g/MT A...

Evaluation of malaria multiplex/nested PCR performance at low parasite densities and mixed infection in Iran: A country close to malaria elimination.

Malaria is still a major public health problem in subtropical and tropical regions. The rapid and accurate diagnosis of malaria remains a challenge in most of the endemic areas. The primary objective of the present study was to evaluate the performance of multiplex/nested PCR in detecting Plasmodium falciparum at low parasite densities and mixed infection.

Data and Corporate Governance in Pharma and Digital Health: A Necessary Regulatory Convergence.

Data and Corporate Governance in Pharma and Digital Health: A Necessary Regulatory Convergence.

Assessing Dental Hygiene Students' Test Anxiety in Examiner-Administered vs. Camera-Supervised OSCEs: A Pilot Study.

The aim of this pilot study was to measure and compare dental hygiene students' level of text anxiety and performance when being tested on an objective structured clinical examination (OSCE) using camera supervision versus direct examiner observation. This randomized, controlled trial, conducted in October 2016, assessed students' anxiety levels and performance using the Zung Self-Rating Anxiety Scale and performance on an OSCE. All 32 first-year students in one U.S. dental hygiene program were invited to p...

High performance and stable mesoporous perovskite solar cells via well crystallized FA0.85MA0.15Pb(I0.8Br0.2)3.

The overall performance of perovskite solar cells (PSCs) depends particularly on the chemical composition and crystalline quality of the perovskite light harvester. Here, the well crystallized mixed-cation lead mixed-halide perovskite films with the optimized composition of FA0.85MA0.15Pb(I0.8Br0.2)3 were achieved by anti-solvent assisted single-step spin-coating in ambient conditions. The resulting PSCs with the well crystallized FA0.85MA0.15Pb(I0.8Br0.2)3 exhibit impressive power conversion efficiency (PC...

Randomized clinical trial to evaluate the efficacy of prostaglandin F to treat purulent vaginal discharge in lactating dairy cows.

The objectives of this study were (1) to assess the effect of purulent vaginal discharge (PVD) on reproductive performance using a 4-point vaginal discharge score (VDS) and (2) to evaluate the effect of PGF treatment in cows with PVD on reproductive performance. Holstein cows (n = 2,473) from 1 commercial dairy farm had their vaginal discharge scored at 32 ± 3 d in milk (DIM) using a 4-point scale. Cows were also scored for body condition score and had their ovaries examined using transrectal ultrasound. A...

Clinical trials go virtual, big pharma dives in.

Grade Groups Provides Improved Predictions of Pathologic and Early Oncologic Outcomes Compared with Gleason Score Risk Groups.

The grade grouping (GG) system was introduced in 2013. Data from academic centers suggests GG better distinguishes between prostate cancer risk groups than the Gleason score (GS) risk groups. We compared the performance of both for predicting pathological/recurrence outcomes using data from Michigan Urological Surgery Improvement Collaborative (MUSIC).

Waist Circumference and Waist-to-Hip Ratio in Law Enforcement Agency Recruits: Relationship to Performance in Physical Fitness Tests.

Lockie, RG, Ruvalcaba, TR, Stierli, M, Dulla, JM, Dawes, JJ, and Orr, RM. Waist circumference and waist-to-hip ratio in law enforcement agency recruits: relationship to performance in physical fitness tests. J Strength Cond Res XX(X): 000-000, 2018-Law enforcement agencies (LEAs) use tests to assess recruit physical fitness. Body fat can influence test performance but is difficult to measure during academy because of time, equipment constraints, and instructor knowledge. This study examined relationships be...

Effect of the use of a model with peer instruction for the teaching of membrane potential and action potential.

A group of teachers from Northeast Brazil developed a model of membrane potentials and action potential and tested the hypothesis that using the peer-instruction model would provide a better performance for students in reading traditional texts and lectures. The results were obtained from 357 students from 20 different courses in 9 different undergraduate programs. All students attended two 100-min theoretical lecture and, at the end of the second lecture, were asked to answer a multiple-choice question (a ...

Blinded and unblinded hypohydration similarly impair cycling time trial performance in the heat in trained cyclists.

Knowledge of hydration status may contribute to hypohydration-induced exercise performance decrements, therefore, this study compared blinded and unblinded hypohydration on cycling performance. Fourteen trained, non-heat acclimated cyclists (age 25 ± 5 y; V̇O 63.3 ± 4.7 mL∙kg∙min; cycling experience 6 ± 3 y) were pair-matched to blinded (B) or unblinded (UB) groups. After familiarisation, subjects completed euhydrated (B-EUH; UB-EUH) and hypohydrated (B-HYP; UB-HYP) trials in the heat (31˚C); 120 m...

Changes of nitrogen-removal performance and that of the bacterial community in a mixed culture comprising freshwater and marine anammox bacteria under averaged environmental condition.

Nitrogen-removal processes using anammox bacteria are expected to achieve high-rate removal while remaining economical, and their practical applications have been investigated. However, anammox bacteria still have unfavorable characteristics for practical use, including susceptibility to a change in environmental conditions. In this study, with an aim of exploring the adaptability of mixed anammox bacteria to environmental conditions, the shift of nitrogen-removal performance and bacterial community in a mi...

Dietary fiber increases the butyrate-producing bacteria and improves growth performance of weaned piglets.

The study investigated the impact of dietary fibers on performance, fecal short-chain fatty acids, nutrients digestibility and bacterial community in weaned piglets with control group (CON), dietary supplementation of 5% corn bran (CB), 5% wheat bran (WB) or 5% soybean hulls (SB). The piglets in CB and WB groups showed greater weight gain and feed efficiency (P < 0.05) in comparation with piglets in CON and SB groups. Fecal samples from piglets in CB, SB and WB groups contained greater (P < 0.05) butyrate l...

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