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10:16 EDT 24th March 2018 | BioPortfolio

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When baby Charlie Gard was diagnosed with a rare mitochondrial disease, his parents located a Professor of Neurology in the USA willing to provide nucleoside therapy which offered a theoretical chance of improvement and successfully raised £1.3 million through crowd funding. The decision that unproven therapy was contrary to Charlie Gard's best interests and that life-sustaining treatment should be withdrawn was devastating for his parents and difficult for their supporters to comprehend. The decision was ...

Flowers for Algernon: The ethics of human experimentation on the intellectually disabled.

Flowers for Algernon is a novel written in 1966 by Daniel Keyes. Since its publication, it has received significant critical acclaim, earning a Nebula science-fiction award, and was also adapted into a feature film. Set in the 1960s, the novel follows the story of Charlie Gordon, an intellectually disabled man who lives a simple but happy life working a cleaning job at a local bakery. Charlie's life, however, faces an abrupt change when he is offered the opportunity to participate in a novel surgical proced...

Responding to parental requests for life-sustaining treatment… relational potential revisited.

One of the most challenging situations for pediatric clinicians is responding to parental requests for life-sustaining medical therapies for a child with profound neurodevelopmental disabilities. These therapies (e.g. intravenous medications and fluids, gastrostomy tube feeds, dialysis, tracheostomy, and/or mechanical ventilation) offer the possibility for the child to live, at home or in a facility, for months or years as opposed to experiencing their imminent death. While relatively rare, the tension surr...

Cultural capital factors associated with life satisfaction in Korean baby boomers.

As aging baby boomers retire, cultural capital is expected to play a major role in representing new types of need for social inclusion for this group of people. This study aims to examine the association between cultural capital and life satisfaction among Korean baby boomers born between 1955 and 1963.

Begin with the End in Mind: A three-part workshop series to facilitate end-of-life discussions with members of the community.

Death is among the most avoided topics of conversation. Although end-of-life planning may greatly benefit individuals and their survivors, research and practice indicate that family, friends, and even health care providers resist discussing end-of-life plans. Consequences of not planning ahead have created a public health issue. This article describes a community-level intervention that facilitates those necessary conversations among elders who have at least begun to talk with others about their wishes. A f...

Using Group Visits To Teach Residents About Advance Care Planning.

Community perspectives of end-of-life preparedness.

While death is a universal human experience, the process of planning for death can be difficult and may be avoided altogether. To understand community perspectives of end-of-life preparedness, we undertook a multi-method study exploring the experiences of 25 community members and 10 stakeholders engaged in end-of-life planning. In addition, card sorting activities and focused discussions with 97 older adults were undertaken to highlight perspectives and needs. Data were analyzed using descriptive statistics...

Mother's attachment history and antenatal attachment to the second baby: the moderating role of parenting efficacy in raising the firstborn child.

In this exploratory study, we examined the associations between mothers' attachment history, parenting efficacy in raising the firstborn child, and antenatal attachment to the second baby. Mothers in the third trimester of pregnancy with their second child were recruited to attend this quantitative study. Data were obtained by means of mother-report questionnaires. Mothers completed questionnaires assessing their attachment to their own mother, parenting efficacy in raising their first child, and antenatal ...

A Microcosting Study of Establishing a Baby Café(®) in Texas.

This article focuses on the costs of opening and running a Baby Café. A Baby Café is an intervention that focuses on providing peer-to-peer support for breastfeeding mothers. Research aim: This study aimed to estimate the costs of establishing and running a Baby Café.

Can a Leaflet with Brief Verbal Instruction Teach Nepali Women How to Correctly Contract Their Pelvic Floor Muscles?

Pelvic organ prolapse is a common disorder for women in Nepal causing symptoms and reduced quality of life. Pelvic floor muscle exercise is a conservative treatment option for pelvic organ prolapse but the effective way to teach women in Nepal is not known. The objective of this pilot study was to determine if an illustrative leaflet with brief verbal instruction could teach Nepali women to correctly contract their pelvic floor muscles.

Nursing infant with acquired toxoplasmosis in the first months of life - a case report.

Toxoplasmosis is caused by Toxoplasma gondii and the probability of this infection occurring in the first months of life is usually low because its transmission is related to eating habits. A 6-month-old nursing infant was diagnosed with acute toxoplasmosis, which was identified through anti- T. gondii IgA, IgM and low-avidity IgG serologic assays, polymerase chain reaction (PCR) and mouse bioassay test although its mother was seronegative. This serological divergence between mother and child led us to inte...

Hand-assisted Approach as a Model to Teach Complex Laparoscopic Hepatectomies: Preliminary Results.

Currently, there are limited and scarce models to teach complex liver resections by laparoscopy. The aim of this study is to present a hand-assisted technique to teach complex laparoscopic hepatectomies for fellows in liver surgery.

The economic impact of prematurity and bronchopulmonary dysplasia.

Bronchopulmonary dysplasia (BPD) is one of the most serious chronic lung diseases in infancy and one of the most important sequels of premature birth (prevalence of 15-50%). Our objective was to estimate the cost of BPD of one preterm baby, with no other major prematurity-related complications, during the first 2 years of life in Spain. Data from the Spanish Ministry of Health regarding costs of diagnosis-related group of preterm birth, hospital admissions and visits, palivizumab administration, and oxygen...

Utilization of Just-in-time Training for Nursing Education using the LA Phonospirometry Asthma Tool.

Just-in-time training (JITT) has been used to teach and re-teach known medical techniques, but has not been used to teach novel techniques. We aimed to assess the performance retention of JITT on a novel asthma exacerbation severity assessment technique known as Los Angeles (LA) Phonospirometry.

Young infants expect an unfamiliar adult to comfort a crying baby: Evidence from a standard violation-of-expectation task and a novel infant-triggered-video task.

Do infants expect individuals to act prosocially toward others in need, at least in some contexts? Very few such expectations have been uncovered to date. In three experiments, we examined whether infants would expect an adult alone in a scene with a crying baby to attempt to comfort the baby. In the first two experiments, 12- and 4-month-olds were tested using the standard violation-of-expectation method. Infants saw videotaped events in which a woman was performing a household chore when a baby nearby beg...

A Contemporary Paradigm: Integrating Spirituality in Advance Care Planning.

In the 25 years since advance care planning first drew the attention of the national healthcare and legal systems, gains in the rate of advance care directive completion have been negligible despite the effort of researchers, ethicists, and lawmakers. With the benefit of sophisticated healthcare technology, patients are living longer. Despite the benefits of increased longevity, it is widely acknowledged that enough has not been done to adequately address end-of-life care decisions at the crossroads betwee...

Teaching frontal sinus anatomy using the frontal sinus masterclass 3- D conceptualization model.

Frontal sinus anatomy is complex and often is a difficult subject to both teach and learn. The traditional surgical dogma of "see one, do one, teach one" is impractical and dangerous in the frontal sinus. Based on the building block three-dimensional conceptualization module, the Frontal Sinus Masterclass (FSMC) was created to teach this anatomy.

Teaching pediatric cardiology with meaning and sense.

Pediatric cardiologists teach complicated concepts to a diverse group of learners that include medical students, nurses, residents, fellows, patients, and parents. Unfortunately, much of what is taught is not retained. In order to increase the likelihood of long-term retention, a cardiologist should teach with both meaning and sense. The authors provide a review of these concepts and give specific examples of how to teach in ways that both make sense and are meaningful to a cardiologist's leaners.

Learning to teach.

In the third year of her PhD at Cambridge, Myfanwy Hill dipped into her skills toolbox to see what competences she has and what she still needs. So, with one eye on the newly fashionable 'portfolio career', and one eye on the unachieved goals on her bucket list, she signed up to teach undergraduate veterinary and medical students.

Low hepatitis C antibody screening rates among an insured population of Tennessean Baby Boomers.

Chronic Hepatitis C Virus (HCV) infection is common and can cause liver disease and death. Persons born from 1945 through 1965 ("Baby Boomers") have relatively high prevalence of chronic HCV infection, prompting recommendations that all Baby Boomers be screened for HCV. If chronic HCV is confirmed, evaluation for antiviral treatment should be performed. Direct-acting antivirals can cure more than 90% of people with chronic HCV. This sequence of services can be referred to as the HCV "cascade of cure" (CoC)....

Baby-Friendly Hospital Initiative and Breastfeeding Among WIC-Participating Infants in Los Angeles County.

Breastfeeding rates among low-income infants lag behind national rates. Policies such as the Baby-Friendly Hospital Initiative (BFHI) improve breastfeeding and may benefit low-income populations such as those who participate in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). A recent effort exists to increase the number of Baby-Friendly designated hospitals in Los Angeles County (LAC). Research aim: This study aimed to determine whether the BFHI effort has had a beneficial...

Charlie Gard and the Limits of Best Interests.

The Tragic Case of Charlie Gard.

Charlie Gard and the Limits of the Harm Principle.

Charlie Gard and the limits of medicine.

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