PubMed Journals Articles About "Prospective Aortic Biobank Of POP-STAR" RSS

02:19 EDT 29th March 2020 | BioPortfolio

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Showing "Prospective Aortic Biobank STAR" PubMed Articles 1–25 of 4,400+

Outcomes in Anomalous Aortic Origin of a Coronary Artery Following a Prospective Standardized Approach.

Anomalous aortic origin of a coronary artery (CA) is the second leading cause of sudden cardiac death in young athletes. Management is controversial and longitudinal follow-up data are sparse. We aim to evaluate outcomes in a prospective study of anomalous aortic origin of CA patients following a standardized algorithm.

Prevalence of Obstructive Sleep Apnea in Patients with Thoracic Aortic Aneurysm: A Prospective, Parallel Cohort Study.

The pathogenesis and etiology of thoracic aortic aneurysms (TAA) are largely unknown. Preliminary data from patients with aortic dissection and abdominal aneurysms suggest a causal link of obstructive sleep apnea (OSA) on aortic disease.

Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort.

Recent genome-wide association studies (GWAS) have discovered ten genetic risk variants for abdominal aortic aneurysms (AAA). To what extent these genetic variants contribute to the pathology of aneurysms is yet unknown. The present study aims to investigate whether genetic risk variants are associated with three clinical features: diameter of aneurysm sac, type of artery and aneurysm related-symptoms in aortic and peripheral aneurysm patients. Aneurysm tissue of 415 patients included in the Aneurysm-Expres...

Balloon-expandable transfemoral transcatheter aortic valve implantation with or without predilation: findings from the prospective EASE-IT TF multicentre registry.

Predilation of the native valve has long been deemed necessary in transfemoral transcatheter aortic valve implantation (TF-TAVI), despite little trial evidence to support its clinical use. As most evidence is derived from retrospective analyses of observational studies, we conducted a two-armed, prospective multicentre registry.

Examining Green Star certification uptake and its relationship with Building Information Modelling (BIM) adoption in New Zealand.

Although academia has concentrated on issues related to green building recently, Green Star, considered as the primary green rating system in New Zealand, has not caught adequate attention, leading to its slow development with a modest number of certified projects. This research aims to explore the perspectives of the key stakeholders in the New Zealand construction industry towards the use of Green Star, as well as its relationship and possible integration with Building Information Modelling (BIM). Specifi...

Longitudinal natural history in young boys with Duchenne muscular dystrophy.

The aim of this prospective multicentric study was to document disease progression in young boys affected by Duchenne muscular dystrophy (DMD) between age 3 and 6 years (±3 months) using the North Star Ambulatory Assessment scale. One hundred fifty-three DMD boys (573 assessments) younger than 6 years (mean: 4.68, SD: 0.84) with a genetically proven DMD diagnoses were included. Our results showed North Star Ambulatory Assessment scores progressively increased with age. The largest increase was observed bet...

Quadricuspid Aortic Valvulopathy and Acute Type A Aortic Dissection.

This case report describes a 55-year-old male who presented with acute Type A aortic dissection. He underwent emergent surgical repair, and his intraoperative transesophageal echocardiography revealed a quadricuspid aortic valve. His aortic root measured 45 mm. Quadricuspid aortic valves have previously been associated with aortic root dilation. This case illustrates the possible association of quadricuspid aortic valves with aortic dissection, similar to what is described with bicuspid valves.

Is the aortic size index relevant as a predictor of abdominal aortic aneurysm? A population-based prospective study: the Tromsø study.

The normal aortic diameter (AD) varies with gender, age and body surface area (BSA). The aortic size index (ASI) is defined as the AD divided by BSA. The primary aim of this study was to investigate if ASI is a predictor of development AAA, and to compare the predictive impact of ASI to that of the absolute AD. . Population-based prospective study including 4161 individuals (53.2% women) from the Tromsø study with two valid ultrasound measurements of the AD and no AAA at baseline (Tromsø 4, 1994). The pri...

Involvement of CREB-regulated transcription coactivators (CRTC) in transcriptional activation of steroidogenic acute regulatory protein (Star) by ACTH.

Studies in vivo have suggested the involvement of CREB-regulated transcription coactivator (CRTC)2 on ACTH-induced transcription of the key steroidogenic protein, Steroidogenic Acute Regulatory (StAR). The present study uses two ACTH-responsive adrenocortical cell-lines, to examine the role of CRTC on Star transcription. Here we show that ACTH-induced Star primary transcript or heteronuclear RNA (hnRNA), parallels rapid increases in nuclear levels of the 3 isoforms of CRTC; CRTC1, CRTC2 and CRTC3. Furthermo...

Does the aortic annulus dilate following aortic root remodelling?

The two main techniques of valve sparing aortic root replacement (VSRR) are remodelling and reimplantation. There is concern that the aortic annulus, which is not stabilized in remodelling technique, may dilate over time and cause aortic regurgitation (AR). Our aim was to assess whether the aortic annulus dilates following VSRR with remodelling technique without aortic annuloplasty.

The Association between Aortic Valve Weight, Echocardiographic Indices, and All-Cause Death in 1,046 Patients Undergoing Surgical Aortic Valve Replacement for Aortic Stenosis.

Aortic valve weight (AVW), a flow independent measure of aortic stenosis (AS) severity, is reported to have heterogeneous associations with the echocardiographic variables used for AS evaluation. Controversy exists regarding its impact on survival after aortic valve replacement (AVR).

Concomitant Wrapping of a Moderately Dilated Ascending Aorta during Aortic Valve Replacement: Postoperative Remodeling of a Distinctive Aorta.

The long-term outcomes of aortic wrapping in patients with ascending aortic aneurysms, which are rare, but can be fatal, remain poorly understood. This retrospective study analyzed the outcomes of aortic diameter, including aortic root, ascending aorta, and proximal arch diameters, after aortic wrapping during aortic valve replacement surgery.

aortic root remodeling with external aortic ring annuloplasty.

An efficacy and safety of valve-sparing aortic root surgery with aortic ring annuloplasty have been demonstrated in various trials. The main technical features of aortic root remodeling with external aortic ring annuloplasty are reported in the article.

Frequency and distribution of corneal astigmatism and keratometry features in adult life: Methodology and findings of the UK Biobank study.

To describe corneal astigmatism in the UK Biobank population and to look for associations with other biometric variables and socio-demographic factors.

Sizes of endografts for endovascular aortic repair: do few fit most?

The endoprostheses for the endovascular aortic repair (EVAR) of abdominal aortic aneurysms (AAA), are currently available in many sizes in reference to the aortic diameters of the proximal neck, but often not all of them are really used. Aim of our work was to review in our experience the most frequent proximal aortic diameters of main bodies that were used, among all those available for EVAR, with respect to the native proximal aortic neck.

Favorable aortic remodeling after thoracic endovascular aortic repair for complicated acute type B aortic dissection.

The implementation of a Biobank network for Chile.

The concept "Biobank" is relatively new in the scientific literature, and is not yet consensually defined, even for the World Health Organization (WHO). However, the use of human samples in biomedical research is a very old activity. The organized development of Biobanks in different places has grown in the last decade. The experience in different countries and continents has been diverse. In this special article we intend to summarize, organize and communicate to the national medical and scientific communi...


Analyze the risk of aortic events (death, dissection or aortic rupture) associated with Marfan syndrome and decide on the optimal timing for preventive surgery on the aortic root.

Aortic dissection at three years post aortic replacement in a patient with Marfan syndrome complicating with abdominal aortic aneurysm: a case report.

Surgical management and outcomes of aortic root in acute type A Aortic Dissection.

To evaluate the short- and middle-term outcomes of different aortic root managements in the setting of acute type A Aortic Dissection (ATAAD): aortic root repair (ARR group), untouched aortic root (UAR group), and Bentall procedure (Bentall group).

Endovascular Repair of Ruptured Ascending Aorta Secondary to Embolized Transcatheter Aortic Valve.

Since its approval by the U.S. Food and Drug Administration in 2011, transcatheter aortic valve replacement has revolutionized the treatment of aortic valvular disease with a rapid increase in utilization. Potentially fatal aortic complications are rare, occurring in 0.2-1.1% of cases-all reported in the early perioperative period. We present a case of a late ascending aortic pseudoaneurysm with rupture secondary to erosion by an embolized transcatheter aortic valve occurring six years after implantation, w...

Placement of a rapid deployment aortic valve in a patient with severely calcified aortic root homograft.

Significant aortic calcification is a known sequelae of homograft aortic root replacement and creates a treatment challenge if these patients require cardiac reintervention. The standard surgical option for patients requiring an aortic valve replacement in the setting of a calcified aortic homograft has been a Bentall procedure, which is high-risk with extended cross-clamp, cardiopulmonary bypass and operative times. We present a patient with a severely calcified aortic homograft who underwent successful va...

Altered 4-D magnetic resonance imaging flow characteristics in complex congenital aortic arch repair.

Interrupted aortic arch (IAA) is a rare but severe congenital abnormality often associated with bicuspid aortic valve (BAV). Complex re-interventions are often needed despite surgical advances, but the impact of aortic hemodynamics in repaired patients is unknown.

Universal Relations for Gravitational-Wave Asteroseismology of Protoneutron Stars.

State-of-the-art numerical simulations of core-collapse supernovae reveal that the main source of gravitational waves is the excitation of protoneutron star modes during postbounce evolution. In this work we derive universal relations that relate the frequencies of the most common oscillation modes observed, i.e., g modes, p modes, and the f mode, with fundamental properties of the system, such as the surface gravity of the protoneutron star or the mean density in the region enclosed by the shock. These rel...

A simple STAR Element Repetitive-PCR (SER-PCR) typing method for the rapid characterization of Staphylococcus aureus.

Staphylococcus aureus repeat (STAR) elements are abundant repeat sequences that are highly variable in numbers and locations within the genome of S. aureus. The evolutionary variation of these repeats occurs rapidly over time and may correlate with their evolutionary lineage. Therefore, the aim of this study is to analyze STAR elements to develop a simple PCR-based typing technique that can be used routinely in clinical laboratories.

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