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PubMed Journals Articles About "Publicis Touchpoint Solutions, Inc." RSS

21:58 EDT 24th September 2018 | BioPortfolio

Publicis Touchpoint Solutions, Inc. PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Publicis Touchpoint Solutions, Inc. articles that have been published worldwide.

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Showing "Publicis Touchpoint Solutions" PubMed Articles 1–25 of 1,800+

A straightforward method for measuring the range of apparent density of microplastics.

Density of microplastics has been regarded as the primary property that affect the distribution and bioavailability of microplastics in the water column. For measuring the density of microplastis, we developed a simple and rapid method based on density gradient solutions. In this study, we tested four solvents to make the density gradient solutions, i.e., ethanol (0.8 g/cm), ultrapure water (1.0 g/cm), saturated NaI (1.8 g/cm) and ZnCl (1.8 g/cm). Density of microplastics was measured via observing ...


Interrogating the Osmotic Pressure of Self-Crowded Bovine Serum Albumin Solutions: Implications of Specific Monovalent Anion Effects Relative to the Hofmeister Series.

The free solvent-based (FSB) model and osmotic pressure was used to probe the ion binding and protein hydration for self-crowded bovine serum albumin in 0.15 M NaF, NaCl, NaI and NaSCN solutions. All experiments were conducted with solutions at pH 7.4. The regressed results of the FSB model behavior to the measured osmotic pressure was excellent, albeit, the osmotic pressure data for NaSCN was noisy. The resulting ion binding and hydration were realistic values and the covariance of the two parameters was e...

Calcium Chloride and Calcium Gluconate in Neonatal Parenteral Nutrition Solutions without Cysteine: Compatibility Studies Using Laser Light Obscuration Methodology.

There are no compatibility studies for neonatal parenteral nutrition solutions without cysteine containing calcium chloride or calcium gluconate using light obscuration as recommended by the United States Pharmacopeia (USP). The purpose of this study was to do compatibility testing for solutions containing calcium chloride and calcium gluconate without cysteine. Solutions of TrophAmine and Premasol (2.5% amino acids), containing calcium chloride or calcium gluconate were compounded without cysteine. Solutio...


Vitrification tendency and stability of DP6-based vitrification solutions for complex tissue cryopreservation.

Vitrification tendency and stability of the amorphous state were analyzed by means of differential scanning calorimetry (DSC) for the vitrification solution DP6, with and without additional solutes to enhance ice suppression. This study is a part of an ongoing research effort to characterize the thermophysical and mechanical properties of DP6 and its derivatives, and their qualities as cryoprotective solutions. DP6 was determined to have a critical cooling rate necessary to ensure vitrification of 2.7 °C/...

Bretschneider and del Nido solutions: Are they safe for coronary artery bypass grafting? If so, how should we use them?

A variety of cardioplegic solutions are being used widely today to arrest the heart during coronary artery bypass grafting (CABG) and other cardiac operations. To minimize interruptions during the surgery for intermittent dosing of the cardioplegia and to facilitate less invasive cardiac procedures, single-shot solutions, including Bretschneider and del Nido solutions, have been introduced. This review examines the evidence regarding the safety and efficacy of Bretschneider and del Nido cardioplegia during ...

Emergency department crowding: A systematic review of causes, consequences and solutions.

Emergency department crowding is a major global healthcare issue. There is much debate as to the causes of the phenomenon, leading to difficulties in developing successful, targeted solutions.

Metabolic effect of alkaline additives and guanosine/gluconate in storage solutions for red blood cells.

Over a century of advancements in the field of additive solutions for red blood cell (RBC) storage has made transfusion therapy a safe and effective practice for millions of recipients worldwide. Still, storage in the blood bank results in the progressive accumulation of metabolic alterations, a phenomenon that is mitigated by storage in novel storage additives, such as alkaline additive solutions. While novel alkaline additive formulations have been proposed, no metabolomics characterization has been perfo...

Nodal-line dynamics via exact polynomial solutions for coherent waves traversing aberrated imaging systems.

We obtain exact polynomial solutions for two-dimensional coherent complex scalar fields propagating through arbitrary aberrated shift-invariant linear imaging systems. These solutions are used to model nodal-line dynamics of coherent fields output by such systems.

Arginine suppresses opalescence and liquid-liquid phase separation in IgG solutions.

Antibody formulation often necessitates the protein concentration to be increased above 100 mg/ml, because of the large therapeutic doses of antibodies required and the volume limitations of subcutaneous injections. However, high concentrations of antibody lead to opalescent states in solution, resulting in safety and application problems. In this study, we investigated the effect of additives on opalescence in IgG solutions. Arginine (Arg) was observed to most effectively suppress opalescence in IgG solu...

Shedding light on the oxygen reduction reaction mechanism in ether-based electrolyte solutions. A study using operando UV-Vis spectroscopy.

We have developed a new effective in-operando methodology for investigating oxygen reduction reactions (ORR) and their mechanisms in non-aqueous solutions, based on UV-Vis spectroscopy in conjunction with various electrochemi-cal techniques. We can follow in-situ the formation and presence of superoxide moieties during ORR as a function of the solvent, cations, anions and additives in solution. Thus, using in-operando UV-Vis spectroscopy, we found evidence for the formation of superoxide radical anions duri...

Evasion of No-Hair Theorems and Novel Black-Hole Solutions in Gauss-Bonnet Theories.

We consider a general Einstein-scalar-Gauss-Bonnet theory with a coupling function f(ϕ). We demonstrate that black-hole solutions appear as a generic feature of this theory since a regular horizon and an asymptotically flat solution may be easily constructed under mild assumptions for f(ϕ). We show that the existing no-hair theorems are easily evaded, and a large number of regular black-hole solutions with scalar hair are then presented for a plethora of coupling functions f(ϕ).

Influence of the solvent system on the stability of doxycycline solutions.

Concentrated solutions of doxycycline are often added to drinking water of animals for oral antibiotic therapy. However, stability concerns of doxycycline in solution involve an accurate selection of the solvent system to ensure that the active substance will remain within the acceptance range during the product shelf-life and to avoid sub-therapeutic dosage. Different solvent systems have been evaluated in order to determine their influence on the stability of concentrated doxycycline solutions. The result...

Improvement of enzymological properties of pepsin by chemical modification with chitooligosaccharides.

In order to improve the enzymological properties and to enhance the stability of pepsin (PP, EC 3.4.23.1), chitooligosaccharide (COS) was used to chemically modify enzyme molecules of PP. The results showed that one protein band appeared on the PAGE diagram, indicating that the enzyme samples reached electrophoresis purity after purification. The molecular weights of the enzymes before (PP) and after (COS-PP) modification were 38.68 KD and 49.55 KD, respectively. The K and V of PP were 2.40 mg/mL and ...

Label-free, Direct Measurement of Protein Concentrations in Turbid Solutions with a UV-Vis Integrating Cavity Absorbance Spectrometer.

Protein-particle conjugates and mixtures have been investigated extensively for their diverse applications in biotechnology. However, general methods to measure protein concentration of protein-particle solutions are lacking. Typically, proteins in turbid solutions require separation or staining with another chromophore to quantitate their concentration. Here we demonstrate a direct, label-free approach to measure protein concentrations in turbid solutions using a UV integrating cavity absorbance spectromet...

Comparison of Histidine-Tryptophan-Ketoglutarate and University of Wisconsin preservation solutions in pediatric liver transplantation.

UW and HTK solutions are the two primary organ preservation solutions most used in the United States. This study analyzes use of the two solutions in all pediatric liver transplants performed at a single center between 2001and 2017. Outcome measures included early graft function, as well as graft and patient survival. Bile duct complications were reviewed. Operative technique, immunosuppressive protocols, and donor acceptance criteria remained uniform among participating surgeons throughout the study period...

Monitoring of toxicity of As(V) solutions by AMPHITOX test without and with treatment with zerovalent iron nanoparticles.

Changes in toxicity of As(V) solutions from acute to chronic exposure have been evaluated by the AMPHITOX test. This test employs Rhinella arenarum, a widely distributed toad in Argentine areas. LOEC values were 6.37 and 1.88 mg L for embryos and larvae, respectively, and serious sublethal effects have been observed. Toxicity of As(V) solutions has been also evaluated after treatment with zerovalent iron nanoparticles (nZVI). After 60 min of treatment with nZVI, As(V) removal was 77%, and neither lethal...

Exact Solutions for Nonlinear Development of a Kelvin-Helmholtz Instability for the Counterflow of Superfluid and Normal Components of Helium II.

Relative motion of the normal and superfluid components of helium II results in the quantum Kelvin-Helmholtz instability (KHI) at their common free surface. We found the integrability and exact growing solutions for the nonlinear stage of the development of that instability. Contrary to the usual KHI of the interface between two classical fluids, the dynamics of a helium II free surface allows reduction to the Laplace growth equation, which has an infinite number of exact solutions, including the generic fo...

Organic Salts Suppress Aggregation and Enhance the Hyperpolarizability of a π-Twisted Chromophore.

Twisted intramolecular charge transfer (TICT) chromophores exhibit extraordinary hyperpolarizabilities, β, and are therefore promising for electro-optic technologies. Nevertheless, centrosymmetric aggregate formation severely diminishes β in concentrated solutions or in polymer matrices. Here we report the remarkable effects of organic salts on the linear and nonlinear optical response of a high-β benzimidazolium-based TICT chromophore, B2TMC-2. Addition of Bu4P+Br- to B2TMC-2 solutions in CHCl3 induces ...

Solvent Dependent Light-Induced Structures in Gem-Dichlorocyclopropanated Polybutadiene Solutions.

The formation of permanent structures upon mild red laser illumination in transparent polydiene solutions is examined in the case of gem-dichlorocyclopropanated polybutadiene (gDCC-PB) polymers bearing 15% functional units of the dichlorocyclopropane groups. The response were found to be distinct from the precursor PB. Whereas fiber-like patterns were clearly observed in both precursor and gDCC-PB solutions in cyclohexane, these were absent in the case of gDCC-PB/ chloroform but were present in the precurso...

Long-term Physicochemical Stability of Concentrated Solutions of Noradrenaline Bitartrate in Polypropylene Syringes for Administration in the Intensive Care Unit.

Intensive care units use drug solutions within higher concentrations to avoid fluid overload. The purpose of this study was to evaluate the physicochemical stability of concentrated solutions of noradrenaline bitartrate in polypropylene syringes during 30 days of storage at 5°C ± 3°C. Five 50-mL syringes containing 0.240 mg/mL of noradrenaline bitartrate in 0.9% sodium chloride were prepared and stored at 5°C ± 3°C during 30 days. Immediately after preparation and periodically during the storage, nora...

Pilot-scale formation of whey protein aggregates determine the stability of heat-treated whey protein solutions-Effect of pH and protein concentration.

Denaturation and consequent aggregation in whey protein solutions is critical to product functionality during processing. Solutions of whey protein isolate (WPI) prepared at 1, 4, 8, and 12% (wt/wt) and pH 6.2, 6.7, or 7.2 were subjected to heat treatment (85°C × 30 s) using a pilot-scale heat exchanger. The effects of heat treatment on whey protein denaturation and aggregation were determined by chromatography, particle size, turbidity, and rheological analyses. The influence of pH and WPI concentration ...

Internal transport of CO from the root-zone to plant shoot is pH dependent.

We investigated the fate of carbon dioxide (CO ) absorbed by roots or internally produced by respiration using gas exchange and stable isotopic labelling. CO efflux from detached leaves supplied with bicarbonate/CO solutions was followed over six cycles. CO effluxes were detected when bicarbonate solution at high pH was used, corresponding to 71~85% of the expected efflux. No CO efflux was detected when CO solutions at low pH were used but CO efflux was subsequently detected as soon as bicarbonate solutions...

Specific Ion Effects on Protein Thermal Aggregation from Dilute Solutions to Crowded Environments.

In this work, we have investigated specific ion effects on protein thermal aggregation from dilute solutions to crowded environments. Ovalbumin and poly(ethylene glycol) have been employed as the model protein and crowding agent, respectively. Our studies demonstrate that the rate-limiting step of ovalbumin thermal aggregation is changed from the aggregation of unfolded protein molecules to the unfolding of the protein molecules, when the solution conditions are varied from a dilute solution to a crowded en...

Optimization of fixative solution for retinal morphology: a comparison with Davidson's fixative and other fixation solutions.

Numerous fixative solutions are available but many are not amenable to the histomorphological preservation of retinae. The investigators specifically focused on retinal histological studies, which rather than 4% formaldehyde (FA), often use Davidson's fixative. However the latter has its limitations. The purpose of this study was to produce a new fixative which maintains retinae closer to the in vivo conditions.

A theory of reactant-stationary kinetics for a mechanism of zymogen activation.

A theoretical analysis is performed on the nonlinear ordinary differential equations that govern the dynamics of a reaction mechanism of zymogen activation. The reaction consists of a primary non-observable zymogen activation reaction that it is coupled to an indicator (observable) reaction. The product of the first reaction is the enzyme of the indicator reaction, and both reactions are governed by the Michaelis-Menten reaction mechanism. Using singular perturbation methods, we derive asymptotic solutions ...


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