PubMed Journals Articles About "SCCM 2020" RSS

01:55 EDT 30th March 2020 | BioPortfolio

SCCM 2020 PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest SCCM 2020 articles that have been published worldwide.

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Showing "SCCM 2020" PubMed Articles 1–25 of 1,400+

Expanding the Degradable Proteome: Designing PROTACs by the Book.

In this issue of Cell Chemical Biology, Li et al. (2020), Hsu et al. (2020), and Potjewyd et al. (2020) expand the target spectrum amenable to protein degradation by designing degraders of the cell cycle checkpoint kinase Wee1 and the polycomb repressive complex 2 (PRC2) via its regulatory EED subunit.

Hospital response to the COVID-19 outbreak: the experience in Shanghai, China.

On 20 January 2020, the first COVID-19 case was reported in Shanghai, China. As of 12th March 2020, 344 cases with laboratory-confirmed COVID-19 infection have been detected in Shanghai, of which three died, 321 patients are discharged, 20 patients still receive ongoing treatments (Shanghai Municipal Health Commission, 2020).

13th Annual Congress of European Association for Haemophilia and Allied Disorders 2020, 5-7 February 2020, The Hague, The Netherlands.

Comment on "Circular RNAs and their Emerging Roles as Diagnostic and Prognostic Biomarkers in Ovarian Cancer," Cancer Lett. 2020 Jan 2; 473 (2020) 139-147.

An invited commentary on "kser B, Contreras AG, Andraus W, Taner T. Current status of combined liver-kidney transplantation. Int J Surg. 2020 Feb 19. pii: S1743-9191(20)30171-0. doi: 10.1016/j.ijsu.2020.02.008."

2019-nCoV acute respiratory disease, Australia: Epidemiology Report 1 (Reporting week 26 January - 1 February 2020).

This is the first epidemiological report of novel coronavirus (2019-nCoV) acute respiratory disease infections reported in Australia at 19:00 Australian Eastern Daylight Time [AEDT] 1 February 2020. It includes data on Australian cases notified during the week 26 January to 1 February 2020 and in the previous week (19 to 25 January 2020), the international situation and current information on the severity, transmission and spread of the 2019-nCoV infection.

No Zones Left Behind: Democratic Hepatocytes Contribute to Liver Homeostasis and Repair.

Despite minimal turnover, liver cells possess immense regenerative capacity. Some studies suggest existence of a hepatocyte subset with such unique capabilities. However, in the current issue of Cell Stem Cell, three independent studies (Chen et al., 2020; Matsumoto et al., 2020, and Sun et al., 2020) demonstrate an equitable homeostatic and reparative potential of all hepatocytes, irrespective of their lobular location or ploidy status.

The energy and enzyme activity landscapes of yeast chorismate mutase under cellular concentrations of allosteric effectors.

In solution, proteins fluctuate among many conformational substates, with their relative free energies determining sub-state populations and energy barriers determining conformational exchange kinetics. It has been suggested that members of the conformational ensemble may be responsible for different protein functions, although it is generally difficult to test such a proposal in most systems. A model protein for deciphering individual substate contributions is the ho-modimeric Saccharomyces cerevisiae chor...

Mind the Gapmer: Implications of Co-transcriptional Cleavage by Antisense Oligonucleotides.

While gapmers efficiently knock down as well as terminate transcription of nascent lncRNAs and mRNAs, Lee and Mendell (2020) and Lai et al. (2020) also demonstrate that Pol II termination is not observed with gapmers targeting the 3' terminal portions of the transcript.

Towards a safer NHS in 2020?

, Lecturer in Law, Birmingham Law School, University of Birmingham, looks back at some patient safety policy publications and crises in 2019 and asks whether the NHS will be any safer in 2020 and whether any lessons have been learnt.

Vision 2020: where are we?

To describe the VISION 2020: The Right to Sight, global initiative for the elimination of avoidable blindness, the contribution of glaucoma to the magnitude of global blindness and priorities going forward.

Volume 15-Change is Coming!

2020 Vision! ChemMedChem Editor David Peralta looks back at the journal's activities in 2019, as well as upcoming Special Collections, features, and developments for ChemPubSoc Europe in 2020. He also introduces the journal's new Editorial and International Advisory Board members.

COVID-19, Australia: Epidemiology Report 2 (Reporting week ending 19:00 AEDT 8 February 2020).

This is the second epidemiological report for coronavirus disease (COVID-19), previously known as novel coronavirus (2019-nCoV), reported in Australia as at 19:00 Australian Eastern Daylight Time [AEDT] 8 February 2020. It includes data on Australian cases notified during the week ending 19:00 AEDT 8 February 2020, the international situation and current information on the severity, transmission and spread of the COVID-19 infection.

Giuseppe Bartoli (1941-2020).

On February 7th, 2020 Giuseppe Bartoli passed away after a short and serious disease. He has been an eminent organic chemist who has left deep marks in the field of organic synthesis and an unbridgeable void in his friends.

Advancing BSNs by 2020: Innovative Educational Progression for Success.

As we approach 2020, with limited time to meet the Institute of Medicine goal of 80 percent baccalaureate in nursing by 2020, there is a need for additional innovative academic progression models with seamless progression to obtain a BSN. A community college and university created a new model for educational progression that resulted in the Associates Degree in Nursing/Bachelor of Science in Nursing Collaborative Program, the first of its kind in this state. The program utilizes the ADN traditional curricul...

Advisory Committee on Immunization Practices Recommended Immunization Schedule for Adults Aged 19 Years or Older - United States, 2020.

At its October 2019 meeting, the Advisory Committee on Immunization Practices (ACIP)* voted to recommend approval of the 2020 Recommended U.S. Adult Immunization Schedule for Persons Aged 19 Years and Older. The 2020 adult immunization schedule, available at, summarizes ACIP recommendations in two tables and accompanying notes. This 2020 adult immunization schedule has been approved by the CDC Director, the American College of Physicians, the American Academ...

CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures.

Two recent studies have uncovered a novel means by which bacteriophages thwart host immunity. Mendoza et al. (2020) and Malone et al. (2020) demonstrate that a nucleus-like proteinaceous structure shields phage DNA from CRISPR-associated nucleases encompassing Cascade-Cas3, Cas9, and Cas12.

2020: A Time for Contemplation and Action.

Depending on which interpretation of the Gregorian and other calendars that you may believe to be the most accurate, the new decade either began on January 1, 2020, or will begin January 1, 2021. In any case, the contemplation of decades and time passing offers a time for appraisal and reflection, a chance to step outside of the day-to-day routines to consider less urgent, and perhaps more important issues that we will face in the near future.

Schistosomiasis - Assessing Progress toward the 2020 and 2025 Global Goals.

With the vision of "a world free of schistosomiasis," the World Health Organization (WHO) set ambitious goals of control of this debilitating disease and its elimination as a public health problem by 2020 and 2025, respectively. As these milestones become imminent, and if programs are to succeed, it is important to evaluate the WHO programmatic guidelines empirically.

MapPIng PI inside cells brings new light to polyphosphoinositide biology.

It is unclear how phosphatidylinositol (PI), the precursor of polyphosphoinositides, is distributed within cell membranes. Pemberton et al. (2020. J. Cell. Biol. and Zewe et al. (2020. J. Cell. Biol. describe new approaches to map the subcellular PI abundance and clarify how polyphosphoinositide metabolism relates to PI distribution.

A Structural Understanding of Class B GPCR Selectivity and Activation Revealed.

Ma et al. (2020) and Liang et al. (2020) describe the cryo-EM structures of three class B G protein-coupled receptors (GPCRs) in complex with native peptides and Gs. Their work establishes the structural basis of peptide specificity and a conserved mechanism of receptor activation and G protein coupling for class B GPCRs.

COVID-19, Australia: Epidemiology Report 5 (Reporting week ending 19:00 AEDT 29 February 2020).

This is the fifth epidemiological report for coronavirus disease 2019 (COVID-19), reported in Australia as at 19:00 Australian Eastern Daylight Time [AEDT] 29 February 2020. It includes data on COVID-19 cases diagnosed in Australia, the international situation and a review of current evidence.

When the Family Treasure Is a Doormat.

Germ cells carry genetic information to the next generation, necessitating special attention to their genome maintenance. Two new studies in this issue of Developmental Cell (Bhargava et al., 2020; Dokshin et al., 2020) reveal an essential function of germ cell-specific protein GCNA in the genome maintenance of germ cells.

If You Like It Then You Shoulda Put Two "RINGs" on It: Delineating the Roles of vPRC1 and cPRC1.

To delineate the roles of variant (vPRC1) and canonical (cPRC1) Polycomb repressive complex 1, Blackledge et al. (2020) and Tamburri et al. (2020) elegantly disrupt RING1A/B catalytic activity without affecting stability of either complex and then explore the precise contribution of vPRC1-mediated H2AK119ub1 to Polycomb-mediated gene repression.

Assessing the Healthy People 2020 Objective to Expand Early Treatment Receipt Among a National Sample of Children with ASD.

To assess the progress of the Healthy People 2020 (HP2020) objective to increase the proportion of children with autism spectrum disorder (ASD) who receive treatment by 48 months old and to examine the relationship between predisposing, enabling, and need factors and age of initial treatment receipt.

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