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01:10 EDT 22nd August 2019 | BioPortfolio

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Capillary Origami with Atomically Thin Membranes.

Small-scale optical and mechanical components and machines require control over three-dimensional structure at the microscale. Inspired by the analogy between paper and two-dimensional materials, origami-style folding of atomically thin materials offers a promising approach for making microscale structures from the thinnest possible sheets. In this letter, we show that a monolayer of molybdenum disulfide (MoS2) can be folded into three-dimensional shapes by a technique called capillary origami, in which the...


Mechanical properties of bovine erythrocytes derived from ion current measurements using micropipettes.

Synchronized data from ion currents and optical microscopy have been used to measure the mechanical properties of individual soft microparticles. This new experimental method draws on the signals generated by each particle as it passes through the tip of a pipette. The technique represents an advance on micropipette aspiration (MA), which uses optical microscopy in isolation. The ionic resistance through the tip provides additional information regarding the progress of particle deformation. The augmented te...

Sampling and multiplexing in lab-on-paper bioelectroanalytical devices for glucose determination.

In this work, we present a multiplexed (eight simultaneous measurements) paper-based electrochemical device developed in a very simple way and using low-cost materials, such as paper, carbon ink and multifunctional connector headers. Meanwhile, we have also combined the paper-based electrochemical platform with a glass-fiber strip in order to integrate easily a sampling step. Both approaches, simultaneous measuring and sampling, have been applied to the determination of glucose using bienzymatic biosensors....


Responses of retinal arterioles and ciliary arteries in pigs with acute respiratory distress syndrome (ARDS).

Acute respiratory distress syndrome (ARDS) is a clinical syndrome of acute lung failure in critically sick patients, which severely compromises the function of multiple organs, including the brain. Although, the optic nerve and the retina are a part of the central nervous system, the effects of ARDS on these ocular structures are completely unknown. Thus, the major goal of this study was to test the hypothesis that ARDS affects vascular function in the eye. ARDS was induced in anesthetized pigs by intratrac...


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