PubMed Journals Articles About "Sanders Trump Pick Proves Never Serious About Taking" RSS

20:13 EST 17th January 2019 | BioPortfolio

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Showing "Sanders Trump Pick Proves Never Serious About Taking" PubMed Articles 1–25 of 1,800+

Erratum for Sanders et al., "FusoPortal: an Interactive Repository of Hybrid MinION-Sequenced Genomes Improves Gene Identification and Characterization".

Findings on 7000 mri of the iam: To scan or not to scan? : A retrospective cohort study.

The pick-up rate of new vestibular schwannoma was 1.6%, in keeping with current literature. After correction for non-significant incidentals, the incidental pick up rate was 11%. When we exclude the clinically non-significant findings of sinus and mastoid opacifications, we found that except for ischaemic changes, the pick-up of new vestibular schwannomas was still the most common important finding, justifying our scan requests. Incidental findings may lead to patient anxiety and require further utilisation...

Validation Study of the Thumb Ossification Composite Index (TOCI) in Idiopathic Scoliosis: A Stage-to-Stage Correlation with Classic Tanner-Whitehouse and Sanders Simplified Skeletal Maturity Systems.

The new simplified thumb ossification composite index (TOCI) based on ossification of the thumb epiphyses and adductor sesamoid has demonstrated simplicity, excellent reliability, and high accuracy for predicting skeletal maturity, comparable with the Sanders simplified skeletal maturity system (SSMS). It was our belief that, because the terminology of the SSMS system has been commonly used for skeletal maturity prediction in idiopathic scoliosis in publications over the past decade, the clinical applicabil...

Work Requirements That Don't Work.

Early in 2018, the Trump administration's Centers for Medicare and Medicaid Services issued a guidance letter outlining a new and controversial kind of Medicaid waiver proposal. The administration invited states to propose waivers that would impose work (or other "community engagement") requirements as a condition of eligibility for Medicaid. The Trump administration and state proponents of work requirements want to force able-bodied Medicaid beneficiaries into the workplace. Critics allege that this is bec...

First Prenatal Diagnosis of a Niemann-Pick Disease Type C2 Revealed by a Cystic Hygroma: A Case Report and Review of the Literature.

The importance of fetal nuchal translucency was highlighted in the early 1990s as a useful first-trimester marker to identify fetal chromosomal abnormalities. Here, we report the prenatal diagnosis of a fetus with Niemann-Pick disease type C initially identified by first-trimester ultrasonographic markers and eventually confirmed by extensive genetic evaluation.

Adult Niemann-Pick disease type C in France: clinical phenotypes and long-term miglustat treatment effect.

Niemann-Pick disease type C (NP-C) is a neurodegenerative lysosomal lipid storage disease caused by autosomal recessive mutations in the NPC1 or NPC2 genes. The clinical presentation and evolution of NP-C and the effect of miglustat treatment are described in the largest cohort of patients with adolescent/adult-onset NP-C studied to date.

Progress and Challenges in Sexual Orientation and Gender Identity Measurement in the First Year of the Trump Administration.

Methyl dihydrojasmonate and lilial are the constituents with an "off-label" insect repellence in perfumes.

Insect repellents are widely used to fend off nuisance mosquitoes and, more importantly, to reduce or eliminate mosquito bites in areas where viruses and other vector-borne diseases are circulating. Synthesized more than six decades ago, DEET is the most widely used insect repellent. Plant-derived compounds are used in a plethora of commercial formulations and natural recipes to repel mosquitoes. They are also used as fragrances. We analysed Bombshell® to identify the constituent(s) eliciting a previously ...

Interregional carbon compensation cost forecast and priority index calculation based on the theoretical carbon deficit: China as a case.

Interregional carbon compensation is an important part of ecological compensation. An accurate accounting of the interregional carbon compensation cost is the foundation for establishing a carbon compensation mechanism. Corresponding to the actual carbon deficit, this paper advances, for the first time, the concept of the theoretical carbon deficit and, improves the calculation method of the interregional carbon compensation cost based on the theoretical carbon deficit. Additionally, this paper, forecasts t...

Trump's Zero-tolerance Policy: Would a Political Response to a Humanitarian Crisis Work?

Perspective taking in a novel signaling task: Effects of world knowledge and contextual constraint.

Perspective taking-the ability to see things from someone else's point of view-can boost success in communication. A signaler might take perspective when designing an utterance that is informative from the receiver's point of view, or the receiver might take perspective when inferring the signaler's communicative intentions. Perspective taking is supposed to play a particularly vital role when people try to communicate in the absence of a conventional signaling system. However, the task demands in such case...

Depressive and socially anxious symptoms, psychosocial maturity, and risk perception: Associations with risk-taking behaviour.

Risk-taking behaviour and onset of mental illness peak in adolescence and young adulthood. This study evaluated the interconnectedness of the domains of risk-taking behaviour, mental health (symptoms of depression and social anxiety), psychosocial maturity, risk perception, age, and gender in a sample of 306 adolescents and young adults. Participants between the ages of 16 and 35 completed online self-report measures assessing risk-taking behaviour, depressive symptoms, socially anxious symptoms, psychosoci...

Sight-over-sound judgments of music performances are replicable effects with limited interpretability.

Virtuosi impress audiences with their musical expressivity and with their theatrical flair. How do listeners use this auditory and visual information to judge performance quality? Both musicians and laypeople report a belief that sound should trump sight in the judgment of music performance, but surprisingly, their actual judgments reflect the opposite pattern. In a recent study, when presented with 6-second videos of music competition performers, listeners accurately guessed the winners only when the video...

Health Policy Was Bustin' Out All Over.

The Trump administration refused to defend important provisions of the ACA in court and pursued rules that could open the door to less-regulated insurance options.

To win at gene therapy, companies pick viruses with production credentials.

The impact of biomarkers analysis in the diagnosis of Niemann-Pick C disease and acid sphingomyelinase deficiency.

Although representing two distinct disease entities, Niemann-Pick disease type C (NP-C) disease and acid sphingomyelinase deficiency (ASMD) share several phenotypic features. The lack of biomarkers was responsible in the past of diagnostic delay. Recently, plasma oxysterols, cholestan-3β,5α,6β-triol (Triol) and 7-ketocholesterol (7-KC) and lysosphingolipids, Lyso-sphingomyelin (Lyso-SM) and Lysosphingomyelin-509 (Lyso-SM-509), have been proposed as diagnostic biomarkers. We aimed to assess the diagnostic...

Cyclodextrin-Based Macromolecular Systems as Cholesterol-Mopping Therapeutic Agents in Niemann-Pick Disease Type C.

Over the last decade, cyclodextrins (CDs) have gained considerable attention as a potential therapeutic intervention in the treatment of the rare genetic condition Niemann-Pick type C disease (NPC). However, the oligosaccharide in its monomeric form suffers from serious side effects, especially from a pharmacokinetic and biodistribution standpoint. CD-based macromolecular systems hold great promise to overcome such limitations and might provide an improved therapeutic approach in reducing cholesterol accumu...

Large pericardial effusion and tamponade in young male with Niemann-Pick disease type C.

Application of a simple methodology to analyze Hydroxypropyl-β-Cyclodextrin in urine using HPLC-LS in early Niemann-Pick disease type C patient.

A new methodology, based on high resolution liquid chromatography with light scatterin detector, is applied to analyze Hydroxypropyl-beta-Cyclodextrin (HPβCD) in urine samples of a child affected by Niemann-Pick Type C disease. The treatment not only stopped disease progression, but has also increased the life expectancy and quality of our patient. The pharmacokinetic of HPβCD in the patient was studied with a 92.8% of HPβCD recovered. At 88 h, no HPβCD was found in the urine. During the treatment, HP...

GEX1A, a Polyketide from Streptomyces chromofuscus, Corrects the Cellular Defects Associated with Niemann-Pick Type C1 in Human Fibroblasts.

We report the first evidence of GEX1A, a polyketide known to modulate alternative pre-mRNA splicing, as a potential treatment for Niemann-Pick type C disease. GEX1A was isolated from its producing organism, Streptomyces chromofuscus, and screened in NPC1 mutant cells alongside several semisynthetic analogues. We found that GEX1A and analogues are capable of restoring cholesterol trafficking in NPC1 mutant fibroblasts, as well as altering the expression of NPC1 isoforms detected by Western blot. These result...

A quasi-experimental study of a mandatory calorie-labelling policy in restaurants: Impact on use of nutrition information among youth and young adults in Canada.

In 2017, Ontario became the first Canadian province to require calorie amounts on menus/menu boards of chain restaurants. The province of British Columbia (BC) implemented a voluntary nutrition information initiative in which calorie and sodium information were available upon request. A quasi-experimental design was used to examine the use of nutrition information in Ontario (mandatory calorie labelling), compared to BC (voluntary policy) and three other provinces with no formal menu labelling policy ('cont...

A minimally invasive (sinus tarsi) approach with percutaneous K-wires fixation for intra-articular calcaneal fractures in children.

The aim of this study was to analyze the management of displaced intra-articular calcaneal fractures in children at our pediatric orthopedic and to determine the results following open reduction via minimally invasive sinus tarsi approach and fixation with Kirschner wires (K-wires). Overall, 25 available cases of calcaneal fractures in children with mean age of 9.8 years were treated by open reduction from January 2010 to December 2015. All patients were followed up from 12 to 30 months (mean: 19 months). C...

Longitudinal development of risk-taking and self-injurious behavior in association with late adolescent borderline personality disorder symptoms.

Self-injurious behavior and risk-taking behaviors are associated with adolescent borderline personality disorder (BPD). Developmental trajectories of self-injurious and risk-taking behavior in predicting BPD have not been fully understood. The aim of the present study was to examine self-injurious and risk-taking behavior development and their prospective influence on BPD symptoms in adolescence. Data (n = 506; 62.06 % females, 14.53 years) from the German Saving and Empowering Young Lives in Europe coh...

Transgender And Cisgender US Veterans Have Few Health Differences.

Transgender people have been able to serve openly in the military since June 2016. However, the administration of President Donald Trump has signaled its interest in reinstating a ban on transgender military service. In March 2018 President Trump issued a revised memorandum that stated, in part, that people with a "history or diagnosis of gender dysphoria" who "may require substantial medical treatment, including medications and surgery-are disqualified from military service except under certain limited c...

Did carbon dioxide emission regulations inhibit investments? A provincial panel analysis of China.

Investments, especially fixed asset investments, greatly affect carbon dioxide (CO) emissions. When investments are concentrated in regions with high CO emissions and high fossil energy consumption, the CO emission reduction targets in these areas are difficult to reach in the short term, and the cost of CO emission abatement is high. The current CO emission regulations focus on existing production activities and consumption behaviors. However, whether an investment, which may affect CO emissions in the lon...

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