PubMed Journals Articles About "Sarepta Therapeutics SRPT Douglas Ingram 2019 Results Earnings" RSS

03:02 EST 9th December 2019 | BioPortfolio

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Showing "Sarepta Therapeutics SRPT Douglas Ingram 2019 Results Earnings" PubMed Articles 1–25 of 41,000+

Sex-Based Disparities in the Hourly Earnings of Surgeons in the Fee-for-Service System in Ontario, Canada.

Sex-based income disparities are well documented in medicine and most pronounced in surgery. These disparities are commonly attributed to differences in hours worked. One proposed solution to close the earnings gap is a fee-for-service payment system, which is theoretically free of bias. However, it is unclear whether a sex-based earnings gap persists in a fee-for-service system when earnings are measured on the basis of hours worked.

Rare primary abdominal ectopic pregnancy in the pouch of Douglas.

A 35-year-old Nepalese woman, referred by her general practitioner for per vaginal spotting and abdominal pain for the past 12 days with a background history of 5 weeks of amenorrhoea and a quantifiable beta-human chorionic gonadotrophin of 18 900 IU/L. Subsequent pelvic ultrasound revealed a cystic lesion with peripheral vascularity in the pouch of Douglas indicating possible ectopic pregnancy with no intrauterine gestational sac seen. Subsequent to that, she underwent a diagnostic laparoscopy that reveale...

Correction to: , by Blumenthal, E.Z, Cordeiro, M.F., Schmetterer, L. Verbin, H.L., and Harris, A. J Ocul Pharmacol Ther 2019;35(8):441-446. DOI: 10.1089/jop.2019.0004.

Book ReviewsHandbook of Clinical Skills (2nd edn) Edited by Peter Kopelman and Jane Dacre CRC Press 2019 Price £24.99. Pp 408 ISBN 9780815366911Asthma: Clinician's Desk Reference J Graham Douglas, Kurtis S Elward CRC Press 2019 Price £59.99. Pp 342 ISBN 9781138113466Chestnut's Obstetric Anesthesia: Principles and Practice (6th edn) Edited by David H Chestnut, Cynthia A Wong, Lawrence C Tsen et a

Genetic parenthood and causation: An objection to Douglas and Devolder's modified direct proportionate genetic descent account.

In a recent publication Tom Douglas and Katrien Devolder have proposed a new account of genetic parenthood, building on the work of Heidi Mertes. Douglas and Devolder's account aims to solve, among other things, the question of who are the genetic parents of an individual created through somatic cell nuclear transfer (i.e. cloning): (a) the nuclear DNA provider or (b) the progenitors of the nuclear DNA provider. Such a question cannot be answered by simply appealing to the folk account of genetic parenthood...

Association Between Childhood Behaviors and Adult Employment Earnings in Canada.

Specifying the association between childhood behaviors and adult earnings can inform the development of screening tools and preventive interventions to enhance social integration and economic participation.

Diabetes Technol Ther 2019;21(8):415-422; DOI: 10.1089/dia.2019.0052.

Alternative measures of body composition and wage premium: New evidence from Indonesia.

This paper examines the relationship between body composition and earnings in a developing country setting. We use body mass index, waist circumference and hip circumference. Exploiting the panel structure of our longitudinal survey, we find that along with BMI, waist circumference is related to higher earnings in Indonesia.

Influenza vaccine for 2019-2020.

Should Trolleys Be Scared of Mice? Replies to Evans and Brandt (2019); Białek, Turpin, and Fugelsang (2019); Colman, Gold, and Pulford (2019); and Plunkett and Greene (2019).

Differences in isoprenoid-mediated energy dissipation pathways between coastal and interior Douglas-fir seedlings in response to drought.

Plants have evolved energy dissipation pathways to reduce photooxidative damage under drought, when photosynthesis is hampered. Non-volatile and volatile isoprenoids are involved in non-photochemical quenching of excess light energy and scavenging of reactive oxygen species. A better understanding of trees' ability to cope with and withstand drought stress will contribute to mitigate the negative effects of prolonged drought periods expected under future climate conditions. Therefore we investigated, if Dou...

Digital Therapeutics: Emerging New Therapy for Neurologic Deficits after Stroke.

Digital therapeutics is an evidence-based intervention using high-quality software, with the sole purpose of treatment. As many healthcare systems are encountering high demands of quality outcomes, the need for digital therapeutics is gradually increasing in the clinical field. We conducted review of the implications of digital therapeutics in the treatment of neurological deficits for stroke patients. The implications of digital therapeutics have been discussed in four domains: cognition, speech and aphasi...

Pathology's historic 2019 incoming residents: Why "the internationalization of pathology" may markedly advance transfusion medicine and cellular therapeutics.

This study had two objectives: (1) to determine if, in the United States of America (US), the proportion of non-US citizen international medical graduates (non-US IMGs) entering pathology residencies had increased (again) in 2019 and (2) to assess how this multi-year trend might impact transfusion medicine in the US.

Douglas MacKay, ND: Defining the Regulatory Landscape for Hemp-based Supplements.

No Abstract Available.

A Tribute to Professor Douglas Warrington Henderson, AO, MB, BS, FRCPA, FRCPath, FHKCPath (Hon): 1942-2018.

Corrigendum to"Ketamine metabolite pilot study in a suicidal depression trial" J Psychiatr Res 117 (2019) 129-134. doi: 10.1016/j.jpsychires.2019.08.005. Epub 2019 Aug 9.

Comment on "Theoretical Investigations on Geometrical and Electronic Structures of Silver Clusters".

We would like to make a few comments on the results reported in a recent paper in this journal by Tsuneda, J. Comput. Chem, 2019, 40, 206. The structures of some pure silver clusters were not correctly assigned. © 2019 Wiley Periodicals, Inc.

Measurement of mRNA therapeutics: method development and validation challenges.

The progression of chemically modified mRNA therapeutics through development pipelines is accelerating for many disease indications and the need to assess these analytes is becoming more routine for the pharmaceutical industry and contract research organizations. This article describes some of the challenges and strategies for performing regulated bioanalysis of modified mRNA therapeutics by comparing the two main analytical approaches - quantitative reverse transcription PCR and branched DNA.

Preemptively Precise: Returning and Updating Pharmacogenetic Test Results to Realize the Benefits of Preemptive Testing.

Sumbawanga eye camp follow-up study 2019.

In 2019 the German Commission for the Prevention of Blindness (DKVB) held an eye camp in the Tanzanian town of Sumbawanga. For patients with mature cataracts and the ability to see light cateracts were treated by manual small incision cataract surgery (MSICS). For the first time in this camp the quality of the results of the cataract operations was measured.

Type 2 Diabetes Variants in the SLC16A11 Coding Region Are Not Loss-of-Function Mutations.

This Matters Arising Response paper addresses the Hoch et al. (2019) Matters Arising paper published concurrently in this issue of Cell Reports. The genetic study in humans revealed a strong association of DNA variants in the SLC16A11 coding region with type 2 diabetes mellitus (T2DM). However, how these T2D variants affect the function of SLC16A11 remains controversial. In Zhao et al. (2019), with studies using genetic knockout mouse models and in vivo gene reconstitution experiments, we demonstrated ga...

Pharmacovigilance 2030: Invited Commentary for the January 2020 "Futures" Edition of Clinical Pharmacology and Therapeutics.

Microplastic abundance in atmospheric deposition within the Metropolitan area of Hamburg, Germany.

Only few studies investigated the input of microplastic particles via the atmosphere, so far. Here, we present results on microplastic concentrations in the atmospheric deposition in the metropolitan region of Hamburg. In total, six investigation sites were equipped with three bulk precipitation samplers each and sampled biweekly over 12 weeks (12/17-03/18). Three sites were located in a rural area south of Hamburg comprising one open field site and two throughfall sites under beech/oak and Douglas fir fo...

Volanesorsen: First Global Approval.

Volanesorsen (Waylivra), an antisense oligonucleotide inhibitor of apolipoprotein CIII (apoCIII) mRNA, is being developed by Ionis Pharmaceuticals through its subsidiary company, Akcea Therapeutics, to treat familial chylomicronemia syndrome (FCS), hypertriglyceridemia and familial partial lipodystrophy (FPL). In May 2019, volanesorsen was approved in the EU for the treatment of adult patients with FCS based on positive results from the multinational, phase III APPROACH and COMPASS studies. Other clinical ...

Defend Thyself and Thy Offspring.

Three recent studies (Dodson and Kennedy, 2019; Lev et al., 2019; Ouyang et al., 2019) reveal that germ granule formation is necessary to protect germline-expressed genes from improper small RNA-mediated silencing. Loss of this protection leads to accumulation of small RNAs, impacting gene expression in multiple subsequent generations.

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