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Showing "Sexaffectivity Autistic Spectrum Disorder" PubMed Articles 1–25 of 7,700+

Recognising autism: a latent transition analysis of parental reports of child autistic spectrum disorder 'red flag' traits before and after age 3.

It has been proposed that parents should be educated about child autistic spectrum disorder (ASD) 'red flag' traits to help professionals identify and address concerning behaviours as early as possible. This study aimed to empirically demonstrate that established/recognised 'red flag' traits in the first 3 years of life would reliably predict ASD risk severity in later childhood, associated with established ASD risk correlates and mirroring functioning diagnostic categories.

Instruments for augmentative and alternative communication for children with autism spectrum disorder: a systematic review.

New technologies designed to improve the communication of autistic children can also help to promote interaction processes and cognitive and social development. The aim of this study was to analyze the instruments used to improve the communication skills of children with autism spectrum disorder. We searched the PubMed and Web of Science databases using the descriptors "autism", "Asperger", "education", "children" and "assistive technology" and selected articles that met the following inclusion criteria: (i...

Like a Rolling Stone: Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder.

Reply to letter to the editor "Like a Rolling Stone: Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder".

Self-Focused Attention and Depressive Symptoms in Adults with Autistic Spectrum Disorder (ASD).

Adults with autistic spectrum disorder (ASD) are at high risk of developing comorbid depressive symptoms and in the general population self-focused attention has been associated with depression. Here, we aimed to examine the relationships between aspects of self-focused attention and symptoms of depression in individuals with a diagnosis of ASD. 113 adults with a diagnosis of ASD completed self-report questionnaires. Results found that higher levels of brooding, and to a lesser degree, reflection predicted ...

Mind perception and moral judgment in autism.

Social difficulties of autistic individuals have been suggested to be caused by mind blindness, the absence of a theory of mind. Numerous studies have investigated theory of mind in autism spectrum disorder or how autistic individuals represent the mental states of others. Here, we have examined, as an alternative, mind perception, namely how individuals perceive the minds of various animate and inanimate entities. Autistic and non-autistic participants demonstrated evidence of a similar two-dimensional min...

Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders.

The purpose of this study was to determine the prevalence of epilepsy and subclinical epileptiform abnormalities in children with autism spectrum disorder (ASD), and to investigate its effects on core autistic symptoms and adaptive behavior skills.

Fragranced consumer products: effects on autistic adults in the United States, Australia, and United Kingdom.

Fragranced consumer products, such as cleaning supplies, air fresheners, and personal care products, can have adverse effects on both air quality and health. This study investigates the effects of fragranced products on autistic individuals ages 18-65 in the United States, Australia, and United Kingdom. Nationally representative population surveys ( = 1137; 1098; 1100) found that, across the three countries, 4.3% of adults ( = 142) report medically diagnosed autism (2.3%), an autism spectrum disorde...

Autistic traits and sleep in typically developing adolescents.

Diagnosed autism spectrum disorders have been associated with a high prevalence of sleep problems, other psychiatric disorders and social deficits in adolescence. However, little is known about the possible connection between subclinical autistic traits and sleep. This study explored whether adolescents with elevated levels of subclinical autistic traits are at heightened risk for sleep problems.

Risk of autistic spectrum disorder in offspring with parental mood disorders: A systematic review and meta-analysis.

The association between mood disorders in parents and autism spectrum disorder (ASD) risk in offspring has been investigated in several studies, but the evidence is inconclusive. This systematic review and meta-analysis will explore whether an association exists between parental mood disorders and ASD risk in offspring.

Attenuated impression of irony created by the mismatch of verbal and nonverbal cues in patients with autism spectrum disorder.

Perception of irony has been observed to be impaired in adults with autism spectrum disorder. In typically developed adults, the mismatch of verbal and nonverbal emotional cues can be perceived as an expression of irony even in the absence of any further contextual information. In this study, we evaluate to what extent high functioning autists perceive this incongruence as expressing irony. Our results show that incongruent verbal and nonverbal signals create an impression of irony significantly less often ...

Communicative misalignment in Autism Spectrum Disorder.

Communication deficits are a defining feature of Autism Spectrum Disorder (ASD), manifest during social interactions. Previous studies investigating communicative deficits have largely focused on the perceptual biases, social motivation, cognitive flexibility, or mentalizing abilities of isolated individuals. By embedding autistic individuals in live non-verbal interactions, we characterized a novel cause for their communication deficits. Adults with ASD matched neurotypical individuals in their ability and...

A Matter of Time: The Necessity of Temporal Language in Research on Health Conditions that Present with Autism Spectrum Disorder.

Relatively consistent findings from recent studies using population-level data identify heightened physical and psychiatric morbidity in autistic people compared to the general population. Health problems that commonly present with autism spectrum disorder (ASD) are generally discussed in the literature as "co-occurring" or "comorbid" regardless of their known or hypothesized causal mechanisms. In this commentary, we introduce a new temporally focused terminology to describe health conditions that present w...

A de novo 2q37.2 deletion encompassing AGAP1 and SH3BP4 in a patient with autism and intellectual disability.

Autistic spectrum disorders are complex neurodevelopmental syndromes characterized by phenotypic and genetic heterogeneity. Further identification of causal genes may help in better understanding the underlying mechanisms of the disorder, thus improving the patients' management. To date, abnormal synaptogenesis is thought to be one of the major underlying causes of autistic spectrum disorders. Here, using oligoarray-based comparative genomic hybridization, we identified a de novo deletion at 2q37.2 locus sp...

Sleep Problems in Adults With Autism Spectrum Disorder and Intellectual Disability.

Sleep problems (SP) are recognized as a common comorbid condition in autism spectrum disorder (ASD) and can influence core autism symptoms and mental and physical health. SPs can be lifelong and have been reported that adults on the autistic spectrum with and without intellectual disability (ID) present SPs (longer sleep latency, frequent night awakenings, and circadian rhythm sleep-wake disorders). A prospective, objective sleep study was conducted in 41 adults with ASD (33 ± 6 years old) and ID and 51 ty...

Aging in people with autism spectrum disorder.

Autism spectrum disorder is characterized by a qualitative alteration in social interaction and communication associated with restricted interests and stereotyped behaviors. This condition will accompany people throughout their lives, with variations in their evolution. Our objectives were to know the evolutionary characteristics of people with autistic spectrum disorder, analyzing cognitive, behavioral, health, mortality and their needs in the aging stage, which will guide the planning of specific support ...

Nucleus Accumbens (NAc) DBS for obsessive compulsive disorder and aggression in an autistic patient: a case report and hypothesis of the role of NAc in autism and co-morbid symptoms.

Autism spectrum disorder (ASD) is a set of developmental disorders characterized by lack of social interaction, verbal and non-verbal communication in the first 3 years of life. It is also associated with several co-morbidities, including epilepsy, aggression, self-mutilating behaviour and obsessive-compulsive behaviour. In some cases this can turn in to obsessive compulsive disorder (OCD). Nucleus accumbens (NAc) plays a key role in reward circuitry and is also involved in the control of OCD and aggression...

Third-Party Sociomoral Evaluations in Children With Autism Spectrum Disorder.

We examined explicit and implicit processes in response to third-party moral transgressions in children with autism spectrum disorder (ASD). Twenty 4- to 7-year-old children with ASD and 19 typically developing controls evaluated dynamic visual stimuli depicting intentional or accidental harm to persons or damage to objects. Moral evaluations, eye fixations, and pupil dilations toward the stimuli were collected. Results indicate a preserved capacity to understand the mental states of perpetrators and an imp...

Autistic social behaviors and the half-empty, half-full cup.

Unusual social behaviors have been central to our notions of autism spectrum disorders since their original descriptions. We have come to recognize that such behaviors are broadly distributed beyond the classic phenotype and may be induced by postnatal experiences involving insufficient care. Sex differences have also been noted, and a paper in the current issue by Mandy and colleagues, demonstrates different longitudinal trajectories in boys and girls in autistic social traits from middle childhood to mid-...

An accessible and efficient autism screening method for behavioural data and predictive analyses.

Autism spectrum disorder is associated with significant healthcare costs, and early diagnosis can substantially reduce these. Unfortunately, waiting times for an autism spectrum disorder diagnosis are lengthy due to the fact that current diagnostic procedures are time-consuming and not cost-effective. Overall, the economic impact of autism and the increase in the number of autism spectrum disorder cases across the world reveal an urgent need for the development of easily implemented and effective screening ...

Disturbance of trace element and gut microbiota profiles as indicators of autism spectrum disorder: A pilot study of Chinese children.

Autism spectrum disorder (ASD) is a neuro-developmental disorder that is characterized by impairments of reciprocal social interaction and restricted stereotyped repetitive behavior. The goal of the present study was to investigate the trace element and gut microbiota profiles of Chinese autistic children and screen out potential metallic or microbial indicators of the disease. One hundred and thirty-six children (78 with ASD and 58 healthy controls) aged from 3 to 7 years were enrolled. The levels of lead,...

Association of Prenatal Exposure to Air Pollution With Autism Spectrum Disorder.

The etiology of autism spectrum disorder (ASD) is poorly understood, but prior studies suggest associations with airborne pollutants.

Assessment of racial and ethnic bias in autism spectrum disorder prevalence estimates from a US surveillance system.

This study assessed potential under-ascertainment of autism spectrum disorder due to missing administrative information for Hispanic and non-Hispanic Black children within the Autism and Developmental Disabilities Monitoring Network. We analyzed data from two Network sites (Colorado and Wisconsin) for surveillance years 2012 and 2014 to determine whether children excluded from autism spectrum disorder prevalence estimates due to missing residency and other information differed from those included by race an...

Sex Differences Along the Autism Continuum: A Twin Study of Brain Structure.

Females might possess protective mechanisms regarding autism spectrum disorder (ASD) and require a higher detrimental load, including structural brain alterations, before developing clinically relevant levels of autistic traits. This study examines sex differences in structural brain morphology in autism and autistic traits using a within-twin pair approach. Twin design inherently controls for shared confounders and enables the study of gene-independent neuroanatomical variation. N = 148 twins (62 females) ...

Homicidal Ideation and Individuals on the Autism Spectrum.

Interest in the relationship between autism and violence has increased in recent years; however, no link has clearly been established between them. Researchers remain curious if autistic people with certain traits (e.g., a history of trauma) are at greater risk of violence than those individuals with autism alone. In this article, we detail two individuals with homicidal ideation (HI) admitted to inpatient psychiatric units who were found to have a diagnosis of autism without language impairment. These case...

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