PubMed Journals Articles About "Sudan Agent Causing Type Occupational Asthma" RSS

05:01 EDT 5th April 2020 | BioPortfolio

Sudan Agent Causing Type Occupational Asthma PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Sudan Agent Causing Type Occupational Asthma articles that have been published worldwide.

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Showing "Sudan agent causing type occupational asthma" PubMed Articles 1–25 of 18,000+

Investigation of the relationship between IL-6 and type 2 biomarkers in severe asthma.

Combination of IL-6 (non-Type 2 asthma) and FeNO or blood eosinophil count (Type 2 asthma) identified asthma endotypes related to asthma severity, exacerbations, and responsiveness to corticosteroids and potential for response to anti-Type 2 and anti-IL-6 treatment.

Determination of Sudan dyes in chili products by micellar electrokinetic chromatography-MS/MS using a volatile surfactant.

A new MEKC-MS/MS method was developed for the determination of four Sudan dyes in chili products. The separation and MS detection conditions were optimized to achieve fast, efficient, selective, and sensitive determination of Sudan I, Sudan II, Sudan III, and Sudan IV dyes. The target compounds were extracted from chili samples with acetonitrile and cleaned by freeze-out. This two-step sample preparation led to excellent extraction efficiency and minimal matrix effect. The analytical performance of the meth...

Raman and IR spectroscopic modality for authentication of turmeric powder.

Deliberate chemical contamination of food powders has become a major food safety concern worldwide. This study used Raman imaging and FT-IR spectroscopy to detect Sudan Red and white turmeric adulteration in turmeric powder. While Sudan Red Raman spectral peaks were identifiable in turmeric-Sudan Red samples, Sudan Red false positive detection was observed in binary Raman images, limiting effective quantitative detection. In addition, white turmeric Raman spectral peaks were unidentifiable in turmeric-white...

Relationship between Serum 25-HydroxyVitamin D and Inflammatory Cytokines in Nigerian Children with Asthma.

Childhood asthma involves a network of mutually interacting inflammatory mediators and cytokines. The influence of serum vitamin D (an immunomodulatory agent) on these cytokines is poorly understood. This study sets out to determine the relationship between serum T-helper cells type 1 cytokines (Interleukins ILs-1β, 2, 6, 8 and 10), type 2 cytokines (ILs 3, 4,5,9,13), ILs-12, 17 and 25-hydroxyvitamin D (25-OHD) in Nigerian children with asthma.: Children with physician-diagnosed asthma and non-asthmatics a...

Dupilumab Efficacy in Patients With Uncontrolled, Moderate-to-Severe Allergic Asthma.

Dupilumab blocks the shared receptor component for interleukin-4 and interleukin-13, key drivers of type 2 inflammation, including immunoglobulin E (IgE)-mediated allergic inflammation in asthma. In the LIBERTY ASTHMA QUEST (NCT02414854) study, dupilumab reduced severe asthma exacerbations and improved forced expiratory volume in 1 second (FEV) in patients with uncontrolled, moderate-to-severe asthma with greater efficacy observed in patients with elevated type 2 inflammatory biomarkers (blood eosinophils a...

Familial Coaggregation of Asthma and Type 1 Diabetes in Children.

The association between atopic and autoimmune disease, particularly asthma and type 1 diabetes, has been debated. Further understanding of the underlying factors associated with the comorbidity in children is warranted.

A novel variant in SERPING1 gene causing angioedema in a patient with C1q low levels.

Bronchial Response to High and Low Molecular Weight Occupational Inhalant Allergens.

Occupational asthma may be induced by high- or low-molecular weight allergens (HMWA or LMWA, respectively). The study was conducted to compare the pattern of bronchial response in 200 HMWA-induced asthmatics (n = 130) and LMWA-induced asthmatics (n = 70).

Spatial distribution of breast cancer in Sudan 2010-2016.

Breast cancer is the most prevalent cancer among females worldwide including Sudan. The aim of this study was to determine the spatial distribution of breast cancer in Sudan.

Genetic Structure of Phlebotomus orientalis (Diptera: Psychodidae) in Leishmaniasis Endemic Foci of Sudan.

Visceral leishmaniasis (VL) remains a major concern in many parts of Sudan. The disease is transmitted by Phlebotomus orientalis. The objective of this study was to determine genetic structure of Phlebotomus orientalis population from 5 geographical regions in Sudan.

Hot Topic: Precision Medicine for Asthma-Has the Time Come?

Asthma is a common inflammatory airway disease, which affects more than 300 million people worldwide. Although conventional drugs are effective for most of the patients with mild-to-moderate asthma, they are less effective for patients with difficult-to-treat or severe asthma. Identification of asthma endotypes and biomarkers will lead to more precise approaches to treat asthma.

Development of an Asthma-Specific Job Exposure Matrix for Use in the United States.

Existing asthma-specific job-exposure matrices (JEMs) do not necessarily reflect current working conditions in the USA and do not directly function with occupational coding systems commonly used in the USA. We initiated a project to modify an existing JEM to address these limitations, and to apply the new JEM to the entire US employed population to estimate quantitatively the extent of probable work-related asthma exposures nationwide.

Asthma: endotypes and phenotypes at a pediatric age.

The concepts of endotype and phenotype have been introduced in the past few years with the purpose of identifying the different variants of asthma in children and adults by the interaction of epigenetic factors, such as genotype, environmental factors, and not inherited factors. All these factors participate in the onset and progression of asthma, as well as environmental allergens, which are the cause of asthma in most children and teenagers. The latest onset may be induced by the characteristics of the en...

Cleaning Products and Work-Related Asthma, 10 Year Update.

To describe the frequency of work-related asthma (WRA) and characteristics of individuals with exposure to cleaning products 1998-2012, compared to 1993-1997.

IL-1RA regulates immunopathogenesis during fungal-associated allergic airway inflammation.

Severe asthma with fungal sensitization (SAFS) defines a subset of human asthmatics with allergy to one or more fungal species and difficult to control asthma. We have reported that human asthmatics sensitized to fungi have worse lung function and a higher degree of atopy, which was associated with higher IL-1RA levels in bronchoalveolar lavage fluid. IL-1RA further demonstrated a significant negative association with bronchial hyperresponsiveness to methacholine. Here, we show that IL-1α and IL-1β are el...

Protein S protects against allergic bronchial asthma by modulating Th1/Th2 balance.

Bronchial asthma is a chronic disease characterized by inflammation, obstruction and hyperresponsiveness of the airways. There is currently no curative therapy for asthma. Type 2 helper T cell response plays a critical role in the pathogenesis of the disease. Protein S is a glycoprotein endowed with anticoagulant, anti-inflammatory and anti-apoptotic properties. Whether protein S can suppress bronchial asthma and be useful for its therapy is unknown.

Occupational exposures should be considered in all patients with non-malignant respiratory diseases.

Occupational exposures to gas, fumes, dust and chemicals contribute to non-malignant respiratory diseases like asthma, chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and community-acquired pneumonia in more than one in ten patients. They may be sick due to inhaling various particles, gases, fumes, or chemicals in the workplace. Hence, these exposures should be considered in all patients with non-malignant respiratory diseases. In an international literature review the occupational burd...

Associated Factors for Asthma Severity in Korean Children: A Korean Childhood Asthma Study.

Childhood asthma has a considerable social impact and economic burden, especially in severe asthma. This study aimed to identify the proportion of childhood asthma severity and to evaluate associated factors for greater asthma severity.

Novel Insights on Sex-Related Differences in Asthma.

Asthma, a common respiratory disease that affects about 10% of the US population, represents a significant public health issue. In the last decade, cumulative evidence has demonstrated sex disparities in asthma, including significant differences in epidemiology, clinical presentation, response to therapies, and health outcomes. Understanding sex-related differences in asthma enables clinicians to provide personalized asthma care and improve asthma outcome.

Persistent asthma from childhood to adulthood presents a distinct phenotype of adult asthma.

In approximately 30% of children with asthma, the condition persists into adulthood. The longer duration of asthma in these patients is a risk factor for poor asthma control. However, the characteristics of adult patients with asthma that has persisted since childhood are not well documented.

ATP/P2X7 axis mediates the pathological process of allergic asthma by inducing M2 polarization of alveolar macrophages.

Recent studies revealed that macrophages are polarized towards the M2 phenotype in an ovalbumin (OVA)-induced asthmatic model. Alveolar macrophages (AMs) are immune barriers in alveoli to various pathogens in the respiratory tract; AMs suppress Th2 cell proliferation, inhibit interleukin (IL)-4, IL-5, and IL-13 secretion, and protect against airway hyperresponsiveness in allergic asthma. However, the polarization status and effects of different types of AMs in the pathogenesis of asthma are not known. ATP/P...

Opportunities for Occupational Therapy on a Primary Care Team.

Leaders in the occupational therapy profession have called for occupational therapy's inclusion in primary care, but little is known about the occupational needs of patients in this setting.

The Burden of Work-Related Asthma in Michigan, 1988-2018.

Exposure to a variety of substances in the workplace can cause new-onset asthma or aggravate pre-existing asthma, both of which are considered work-related asthma (WRA). Understanding trends in the nature and causes of WRA can assist in the diagnosis and management of adult patients with asthma.

Increased type 2 inflammation post rhinovirus infection in patients with moderate asthma.

Rhinovirus (RV) infections are a major cause of exacerbations in patients with asthma. Experimental RV challenges can provide insight into the pathophysiology of viral exacerbations. Previous reports, investigating mild or moderate asthma patients, have shown an upregulation in type 2 inflammation post RV infection, however, studies specifically involving asthma patients taking inhaled corticosteroids have concentrated on symptoms and lung function, rather than the inflammatory response. Eleven moderate ast...

Inflammatory mechanisms linking maternal and childhood asthma.

Asthma is a chronic inflammatory airway disease characterized by airway hyperresponsiveness, inflammation, and remodeling. Asthma often develops during childhood and causes lifelong decrements in lung function and quality of life. Risk factors for childhood asthma are numerous and include genetic, epigenetic, developmental, and environmental factors. Uncontrolled maternal asthma during pregnancy exposes the developing fetus to inflammatory insults, which further increase the risk of childhood asthma indepen...

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