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PubMed Journals Articles About "Takeda Global Research & Development Center, Inc." RSS

12:51 EST 11th December 2018 | BioPortfolio

Takeda Global Research & Development Center, Inc. PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Takeda Global Research & Development Center, Inc. articles that have been published worldwide.

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Showing "Takeda Global Research Development Center" PubMed Articles 1–25 of 44,000+

Building a Global Culture of Science - The Vietnam Experience.

We detail the lessons learned, challenges, achievements, and outlook in building a chemistry research center in Vietnam. Through the principles of 'global science', we provide specific insight into the process behind establishing an internationally-competitive research program - a model that is scalable and adaptable to countries beyond Vietnam. Furthermore, we highlight the prospects for success in advancing global science education, research capacity building, and mentorship.


Uppsala Clinical Research Center-development of a platform to promote national and international clinical science.

Uppsala Clinical Research Center (UCR) is a non-profit organization that provides service for clinical research aiming for development and improvement of health care in Sweden and worldwide. UCR was started in 2001 with the ambition to shift the focus of clinical research from new medications or devices launched by the industry to problem-based research on issues identified in clinical reality, for example through the national quality registries. In order to accomplish these goals, UCR has established servi...

Nothing about us without us: the importance of local collaboration and engagement in the global study of autism.

Our current understanding of autism and other developmental disorders is primarily based on research conducted in high-income countries, predominantly in North America and Europe. Even within high-income countries, White participants are overrepresented in autism research. There is now increased recognition that a more global and diverse research representation is warranted. This paper argues that in order for global and diverse research efforts to be effective, it is essential to collaborate and engage wit...


Letter--Incorporating Real-World Evidence and Patient Value Criteria into Value-Based Frameworks for Relapsed/Refractory Multiple Myeloma.

Orlowski has received research funding from Amgen, BioTheryX, Bristol-Myers Squibb, Celgene Corporation, and Takeda Pharmaceuticals; honoraria from Amgen, Bristol-Myers Squibb, Celgene Corporation, Janssen, Millennium Pharmaceuticals, and Onyx Pharmaceuticals; and is a member of advisory boards for Amgen, Bristol-Myers Squibb, Celgene Corporation, Incyte, Kite, Legend Biotech, Sanofi-Aventis, and Takeda Pharmaceuticals.

Theoretical psychology at the University of Alberta as social science during the Cold War.

We examine the University of Alberta's Center for Advanced Study in Theoretical Psychology (1965-1990) in the context of social science conducted during the Cold War. We begin by considering the center with respect to three important properties of social science at this time: an emphasis on interdisciplinarity, a focus on theory, and a preference for quantitative methods. Our analysis suggests that center activities also exhibited these characteristics. They were highly interdisciplinary, they were concerne...

Measurement of three-dimensional wavefronts using the Ichikawa-Lohmann-Takeda solution to the irradiance transport equation.

In this paper, we use the irradiance transport equation and the Fourier transform-based experimental solution given by Ichikawa-Lohmann-Takeda. We analyze experimental factors such as the digital filter, the introduced error for the rotation and period of the Ronchi ruling, and a new method is demonstrated for the measurement of 3D wavefront information.

Experience in the global forum of bioethics in research. Challenges for the ethical review in Chile.

The Global Forum on Bioethics in Research annually convenes a number of researchers, bioethicists and stakeholders with a shared interest in the ethics of conducting research in low and middle-income countries (LMIC). It provides a useful platform to discuss ethical issues that affect research practice in different scenarios, promoting ethically conducted research, global development for health research ethics and partnerships between the global north and south. As participant of the last three meetings, in...

Evaluation of a Center of Research Excellence in Polycystic Ovary Syndrome as a Large-Scale Collaborative Research Translation Initiative, Including Evaluating Translation of Guideline Impact.

Research translation and evaluation are often underconsidered in research design and implementation thus limiting research benefit to the end user. In this article, we first describe a best practice approach to evaluation, for a center of research excellence in polycystic ovary syndrome. Within this, we outline a comprehensive research translation program with inbuilt evaluation of the first (2018). We seek to provide a real-world example of comprehensive approaches to evaluation and research translation.

Estimating the cost of vaccine development against epidemic infectious diseases: a cost minimisation study.

The Coalition for Epidemic Preparedness Innovations was established in 2016, to develop vaccines that can contribute to preparedness for outbreaks of epidemic infectious diseases. Evidence on vaccine development costs for such diseases is scarce. Our goal was to estimate the minimum cost for achieving vaccine research and development preparedness targets in a portfolio of 11 epidemic infectious diseases, accounting for vaccine pipeline constraints and uncertainty in research and development preparedness out...

The Society of Thoracic Surgeons General Thoracic Surgery Database: 2018 Update on Research.

Through the leadership of the Society of Thoracic Surgeons (STS) Workforce on Research Development, the STS Research Center now offers three programs that facilitate outcomes research utilizing the STS General Thoracic Surgery Database (GTSD). (1) The Access and Publications Program supports STS-sponsored projects with data analysis conducted at an STS approved data analytic center, (2) the STS Task Force for Funded Research (TFR) helps STS investigators pursue extramural research funding for projects analy...

Integrating Palliative Care Into Global Health Initiatives: Opportunities and Challenges.

The landscape of global health is quickly evolving as international health care systems and nursing organizations are developing solutions to dilemmas that face the global village and planet as a whole. Nurses remain key players in advancing all major transnational initiatives. Despite admirable efforts by many governing bodies to unify globalized health improvement, palliative care as a specialty has often not been included as a priority for health research, education, practice, or policy. The purpose of t...

Bibliometric analysis of global publications in medication adherence (1900-2017).

Medication non-adherence is a worldwide problem. The aim of this study was to assess the global research output, research trends and topics that shaped medication adherence research.

A novel allele for inducible Cre expression in germinal center B cells.

The germinal center reaction is essential for efficient humoral immunity, but it can also give rise to B cell lymphomas. Cre/loxP-mediated conditional gene knock-out or knock-in can be used for the genetic manipulation of germinal center B cells in vivo. Here we present a novel allele, Cγ1-CreERT2, that allows for timed activation of Cre recombinase in a small fraction of germinal center B cells. This allele will be useful to study normal and malignant germinal center B cell development in vivo. This artic...

Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues.

Rheumatic heart disease (RHD) is an avoidable disease of poverty that persists predominantly in low resource settings and among Indigenous and other high-risk populations in some high-income nations. Following a period of relative global policy inertia on RHD, recent years have seen a resurgence of research, policy and civil society activity to tackle RHD; this has culminated in growing momentum at the highest levels of global health diplomacy to definitively address this disease of disadvantage. RHD is ine...

Global research partnerships in advancing public health: A case study on India.

Collaborative research is integral to medicine. Multi-national and multi-institutional research partnerships produce advances in medicine and public health that have a significant societal impact. Developing nations can gain from such collaborative partnerships in achieving progress in sustainable development goals. However, it is important that the research agenda is relevant to the region where studies are conducted. Funding of research by the national government and regional organisations will ensure tha...

Opportunities and Challenges in Global Perinatal Research.

The global plight of stillbirths and neonatal mortality is concentrated in low- and middle-income countries. The ambitious targets introduced by the World Health Organization in the Every Newborn Action Plan demand a commitment to research that promotes equitable perinatal outcomes.

Developmental disabilities among children younger than 5 years in 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

The Sustainable Development Goals (SDGs) mandate systematic monitoring of the health and wellbeing of all children to achieve optimal early childhood development. However, global epidemiological data on children with developmental disabilities are scarce. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 provides a comprehensive assessment of prevalence and years lived with disability (YLDs) for development disabilities among children younger than 5 years in 195 countries and territories ...

The Binds of Global Health Partnership: Working out Working Together in Sierra Leone.

Global health partnerships (GHPs) are the conceptual cousin of partnerships in the development sphere. Since their emergence in the 1990s, the GHP mode of working and funding has mainly been applied to single-disease, vertical interventions. However, GHPs are increasingly being used to enact health systems strengthening and to address the global health worker shortage. In contrast to other critical explorations of GHPs, we explore in this article how the fact, act, and aspiration of binding different actors...

Contemporary global perspectives of medical students on research during undergraduate medical education: a systematic literature review.

The need for increased expertise in evidence-based medicine and concerns about the decreasing numbers of physician-scientists have underscored the need for promoting and encouraging research in medical education. The critical shortage of physician-scientists has assumed a dimension demanding a coordinated global response. This systematic review examined the perceptions of medical students regarding research during undergraduate medical school from a global perspective.

Recent Advances in Drug Development and Regulatory Science in China.

As the second largest pharmaceutical market with a great potential for future growth, China has drawn much attention from the global pharmaceutical community. With an increasing government investment in biomedical research, the domestic biopharmaceutical (biotechnological) companies in China are turning their attention to the development of innovative medicines and targeting the global market. To introduce innovative products to Chinese patients sooner, to improve the efficiency of its review and approval p...

Prospects for national biological big data centers.

In the era of big data, scientific big data have become the new driving force for both science and technology innovation and social and economic development. China is a powerhouse in generating vast quantities of biological data, which are an essential strategic resource for population health and national security. The current situation of data loss due to the isolated data storage and the lack of systematic data monitoring and management, and the heavy dependency on international biological data centers ur...

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study.

The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required.

Language development delay in 24-month-old children at a health care center of the City of Buenos Aires.

Language development delay is a frequent challenge for pediatricians and other health care providers. The main objective of this study was to establish its prevalence among children attending a health care center.

The relationship between exclusive breastfeeding and infant development: A 6- and 12-month follow-up study.

Breastfeeding offers several advantages for infants with research suggesting that it benefits development, including cognitive and language development. However, limited research has examined the benefits in infants under one year.

The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2018 Update on Research.

The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. The most recent bi-annual feedback report to participants includes analysis of data submitted from 125 hospitals, representing nearly all centers performing pediatric and congenital heart operations in the United States and Canada. In addition to serving as a platform for reporting of outcomes and for quality improvement, the database con...


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