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Technical Specifications Submitting Data Studies Webinar 2019 2019 PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Technical Specifications Submitting Data Studies Webinar 2019 2019 articles that have been published worldwide.
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Three recent studies (Dodson and Kennedy, 2019; Lev et al., 2019; Ouyang et al., 2019) reveal that germ granule formation is necessary to protect germline-expressed genes from improper small RNA-mediated silencing. Loss of this protection leads to accumulation of small RNAs, impacting gene expression in multiple subsequent generations.
The 2015 ACMG/AMP guidelines established a classification system for sequence variants; however, the broad scope of these guidelines necessitates specification of evidence types for specific genes or diseases of interest. Since publication of the guidelines, both general use and disease-focused specifications have emerged to aid in accurate application of ACMG/AMP evidence types. This article summarizes the approaches to, and rationale for, specifying three evidence categories (population frequency data, va...
A Commentary on "Effect of Parkinson's Disease on Primary Total Joint Arthroplasty Outcomes: A Meta-Analysis of Matched Control Studies" (Int J Surg 2019; Sep 26;71:124-131. doi: 10.1016/j.ijsu.2019.09.013).
In their letter to the editor commenting on our call for improved characterization and quantification of drought in ecological studies (Slette et al., 2019), Zang et al. (2019) take issue with the use of standardized drought indices, one of the options we suggested for providing needed climatic context for drought studies.
The 2019 Pittcon was held at the Philadelphia Convention Center with approximately 12,500 attendees from 80 countries, 155 technical sessions, an aggregate of 80 additional poster, networking and workshop sessions, and 750 corporate exhibitors on the exposition floor. Pittcon 2019 featured two main sessions directly related to breath diagnostics research. These were a symposium entitled "Human Exhaled Breath Aerosol (EBA) Sampling and Analysis: Applications for Clinical Diagnostics and Environmental Exposur...
Venkatramani and Parekh, Does the Use of a Robot Decrease the Complication Rate Adherent to Radical Cystectomy? A Systematic Review and Meta-Analysis of Studies Comparing Open with Robotic Counterparts by Tzelves et al. (From: Tzelves L, Skolarikos A, Mourmouris P, et al. J Endourol 2019;33:985; DOI: 10.1089/end.2019.0689).
This special issue of the Journal of Integrative Bioinformatics presents an overview of COMBINE standards and their latest specifications. The standards cover representation formats for computational modeling in synthetic and systems biology and include BioPAX, CellML, NeuroML, SBML, SBGN, SBOL and SED-ML. The articles in this issue contain updated specifications of SBGN Process Description Level 1 Version 2, SBML Level 3 Core Version 2 Release 2, SBOL Version 2.3.0, and SBOL Visual Version 2.1.
Challenging dogma is a frightful thing. Since Aagard, et al (Sci Transl Med 2014;6:237ra65) reported that normal placenta harbors a microbiome that resembles the microbiome of the oral cavity, challenging the prevailing dogma of the sterile uterine environment, investigative teams have published conflicting results either refuting or confirming their findings. Recently, Kuperman, et al, (BJOG 2019;Aug 2:https://doi.org/10.1111/1471-0528,15896) reported analyses of 28 human placentas and 6 murine placentas a...
In two recent issues of Nature, Ellis et al. (2019) and Liu et al. (2019) examine mechanisms that influence clonal dynamics in the epidermis during development and homeostasis, respectively. These studies provide insight into the selection process that determines which cells expand and which cells are lost.
Colorectal cancer (CRC) screening generally starts screening by the age of 50 based on guidelines. Lately however, a U.S. guideline recommended to start CRC screening from age 45 and, very recently, two studies were published that addressed young-onset in Europe (in part) (Vuik et al., 2019; Araghi et al., 2019).
Nutrition research is plagued by the reproducibility crisis. Reconciling nutrition studies involving microbiome data presents a modern challenge for researchers. In this issue of Cell Host & Microbe, Bisanz et al., 2019 demonstrate a comprehensive methodology for meta-analysis of microbiome sequence data from high-fat-diet intervention studies.
The authors of this response outline numerous factual errors and mischaracterizations about their prior work made by Dreher et al (2019). The authors reaffirm their original findings and conclusions and further argue that substantial empirical evidence not reviewed by Dreher et al (2019) support the conclusions reached by Spurlock and Hunt (2008) and Phelan (2012).