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PubMed Journals Articles About "Twitter Launches Initiative Direct Users Towards Credible Information∨derfield=score∨derval=DESC" RSS

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Showing "Twitter Launches Initiative Direct Users Towards Credible Information" PubMed Articles 1–25 of 15,000+

Hyperketolactia occurrence before or after artificial insemination is associated with a decreased pregnancy per artificial insemination in dairy cows.

The reproductive parameters of dairy cattle have continuously declined worldwide over the last 50 years. Nutritional imbalances are identified as risk factors for this decrease of reproductive performance. The present paper aims to quantify the decrease in the pregnancy per artificial insemination (P/AI) in the case of high milk ketones before and after AI. A total of 388,731 test-day from the Brittany Milk Recording Program in France from 226,429 cow-lactations were provided for this trial. For each test-d...


Return to Sport After Bilateral Single Stage Total Hip Arthroplasty Using the Direct Anterior Approach: A Case Control Study.

Total hip arthroplasty (THA) is currently performed on active patients with increasing functional demands. Single stage bilateral THA is indicated in younger patients in good general health. Our objective is to evaluate the return to sport (RTS) in patients who underwent bilateral single stage THA compared to unilateral THA.

Eliminating MRSA transmission in a tertiary neonatal unit-A quality improvement initiative.

Health care facility-onset methicillin-resistant Staphylococcus aureus (HO-MRSA) colonization or infection is a major cause of health care-associated infection (HAI) worldwide. HAIs are preventable and considered a health care quality outcome indicator. A quality improvement project to eliminate HO-MRSA transmission was conducted in a tertiary care neonatal unit over a 9-month period, and sustainability data were monitored. The primary aim of this project was to achieve zero transmission of MRSA among all n...


A Therapeutic International Normalized Ratio Results in Smaller Infarcts and Better Outcomes for Patients with Ischemic Stroke.

Prior studies have shown that warfarin is effective for both primary and secondary stroke prevention in individuals with atrial fibrillation. It is also known that those on warfarin with atrial fibrillation often have poorer long-term poststroke outcomes, possibly because cardioembolic strokes tend to be larger and more severe. Less is known regarding the direct effect of the international normalized ratio (INR) value at the time of stroke on severity or long-term functional status.

Viral mumps: Increasing occurrences in the vaccinated population.

Before the introduction of the vaccine, mumps was the most common salivary gland disease and was one of the most common infectious diseases in children globally. Following the introduction of the mumps vaccine in 1967, the disease was almost nonexistent in the United States and was only found to occur in nonvaccinated patients, and even then, it did not present in epidemic portions because of the extent of vaccination in the population at large. Beginning in the early 2000s, viral mumps began to present its...

Household transmission and disease transmissibility of a large HAV outbreak in Lazio, Italy, 2016-2017.

A major outbreak of Hepatitis A Virus (HAV) has swept through Europe between mid-2016 and 2017, mainly within the community of men who have sex with men (MSM). Over the same period, about 1000 outbreak-related cases of acute Hepatitis A (AHA) were recorded in Lazio region, Italy. We calibrated a Bayesian model to reconstruct likely transmission events within all 44 households where multiple infections were recorded, representing a total of 103 cases from the HAV outbreak in Lazio. Based on information on th...

Two ways of escaping from oxidative RNA damage: Selective degradation and cell death.

Reactive oxygen species (ROS) are produced during normal cellular metabolism, and various oxidized compounds are formed by the ROS attack. Among oxidized bases, 8-oxo-7,8-dihydroguanine (8-oxoG) is most abundant and seems important with respect to the maintenance and transfer of genetic information. The accumulation of 8-oxoG in messenger RNA may cause errors during codon-anticodon pairing in the translation process, which may result in the synthesis of abnormal proteins. Organisms that use oxygen as the so...

Investigating the effects of transcranial direct current stimulation on obstacle negotiation performance in Parkinson disease with freezing of gait: A pilot study.

Identification of potential biomarkers on microarray data using distributed gene selection approach.

In recent times, several feature selection (FS) methods have introduced to identify the biomarkers from gene expression datasets. It has gained extensive attention to solve cancer classification problem, but they have some limitations. First, the majority of FS approaches increases the computational cost due to the centralized data structure. Second, an irrelevant ranked gene that could perform well regarding classification accuracy with suitable subset of genes will be left out of the selection. To resolve...

Automatic detection and sonification of nonmotor generalized onset epileptic seizures: Preliminary results.

Long-term video-EEG monitoring has improved diagnosis and treatment of epilepsy, especially in children. However, the amount of data neurophysiologists must analyze has grown remarkably. The main purpose of this paper is to provide a diagnostic support to speed up and ease EEG interpretation for a specific application concerning absence seizures, a type of non-motor generalized epileptic seizures. The proposed method consists of a pre-processing step where signals are filtered through the Stationary Wavelet...

Insights into the mechanisms and dynamics of energy transfer in plant light-harvesting complexes from two-dimensional electronic spectroscopy.

During the past two decades, two-dimensional electronic spectroscopy (2DES) and related techniques have emerged as a potent experimental toolset to study the ultrafast elementary steps of photosynthesis. Apart from the highly engaging albeit controversial analysis of the role of quantum coherences in the photosynthetic processes, 2DES has been applied to resolve the dynamics and pathways of energy and electron transport in various light-harvesting antenna systems and reaction centres, providing unsurpassed ...

Cannabidiol improves behavioural and neurochemical deficits in adult female offspring of the maternal immune activation (poly I:C) model of neurodevelopmental disorders.

Cognitive impairment is a major source of disability in schizophrenia and current antipsychotic drugs (APDs) have minimal efficacy for this symptom domain. Cannabidiol (CBD), the major non-intoxicating component of Cannabis sativa L., exhibits antipsychotic and neuroprotective properties. We recently reported the effects of CBD on cognition in male offspring of a maternal immune activation (polyinosinic-polycytidilic acid (poly I:C)) model relevant to the aetiology of schizophrenia; however, the effects of ...

Stimulating the Left Dorsolateral Prefrontal Cortex Improves the Memory Representation of Threats among Individuals with High Avoidant Attachment.

Prior research has suggested that individuals with high avoidant attachment may demonstrate a vigilant attentional bias and selective attentional avoidance towards attachment-related negative information (threat information). Similarly, some evidence suggests that impairment of hot working memory (WM) or emotional-related WM occurs in highly avoidant individuals. Moreover, functional MRI studies have demonstrated that the less-activated left dorsolateral prefrontal cortex (L-DLPFC) is related to the impairm...

Hyaluronic acid coated electrospun chitosan-based nanofibers prepared by simultaneous stabilizing and coating.

Chitosan (CS) and hyaluronic acid (HA) are two oppositely charged natural polysaccharides used widely for preparation of nanofibrous scaffolds for tissue engineering applications. Here, we prepared composite fibers composed of CS and HA by electrospinning and subsequent coating. In this regard, two approaches were applied for coating CS nanofibers by HA. In the first method, electrospun nanofiner was first neutralized and then coating was done (HA/CS1), while in the second approach, neutralization and coati...

Further analyses on the phylogeny of the subclass Scuticociliatia (Protozoa, Ciliophora) based on both nuclear and mitochondrial data.

So far, the phylogenetic studies on ciliated protists have mainly based on single locus, the nuclear ribosomal DNA (rDNA). In order to avoid the limitations of single gene/genome trees and to add more data to systematic analyses, information from mitochondrial DNA sequence has been increasingly used in different lineages of ciliates. The systematic relationships in the subclass Scuticociliatia are extremely confused and largely unresolved based on nuclear genes. In the present study, we have characterized 7...

MRI reporter gene MagA suppresses transferrin receptor and maps Fe dependent lung cancer.

As a magnetic resonance imaging (MRI) reporter gene, MagA has become a powerful tool to monitor dynamic gene expression and allowed concomitant high resolution anatomical and functional imaging of subcellular genetic information. Here we establish a stably expressed MagA method for lung cancer MRI. The results show that MagA cannot only enhance both in vitro and in vivo MRI contrast by specifically alternating the transverse relaxation rate of water, but also inhibit the malignant growth of lung tumor. In a...

Amino acid transporter SLC6A14 depends on heat shock protein HSP90 in trafficking to the cell surface.

Plasma membrane transporter SLC6A14 transports all neutral and basic amino acids in a Na/Cl - dependent way and it is up-regulated in many types of cancer. Mass spectrometry analysis of overexpressed SLC6A14-associated proteins identified, among others, the presence of cytosolic heat shock proteins (HSPs) and co-chaperones. We detected co-localization of overexpressed and native SLC6A14 with HSP90-beta and HSP70 (HSPA14). Proximity ligation assay confirmed a direct interaction of overexpressed SLC6A14 with ...

Identification of the perturbed metabolic pathways associating with prostate cancer cells and anticancer affects of obacunone.

Functional metabolomics could bring correlative information about specific cell types under different conditions for exploring cell properties and functions. In this study, we adopt a non-targeted cell metabolomics strategy to reveal the proliferation inhibition mechanism of obacunone on 22RV1 prostate cancer cells. Using high-throughput liquid chromatography-high definition mass spectrometry combined with pattern recognition methods was performed to analyze the cell metabolic profiles and pathway of obacun...

Identification and characterization of three CXC chemokines in Asian swamp eel (Monopterus albus) uncovers a third CXCL11_like group in fish.

Chemokines direct cell migration in development and immune defense, and bridge between innate and adaptive immune responses. The chemokine gene family has been rapidly evolving and has undergone species/lineage-specific expansion. Mammals possess inflammatory CXC chemokines CXCL1-8/15 and CXCL9-11 sub-groups, and homeostatic CXCL12-14, 16-17. Orthologues of mammalian CXCL12-14, three chemokines related to CXCL1-8/15 (CXCL8_L1-3), two chemokines related to CXC9-11 (CXCL11_L1-2), and five fish-specific chemok...

State-unspecific patterns of whole-brain functional connectivity from resting and multiple task states predict stable individual traits.

An increasing number of functional magnetic resonance imaging (fMRI) studies have revealed potential neural substrates of individual differences in diverse types of brain function and dysfunction. Although most previous studies have inherently focused on state-specific characterizations of brain networks and their functions, several recent studies reported on the potential state-unspecific nature of functional brain networks, such as global similarities across different experimental conditions or states, in...

Histological validation of per-bundle water diffusion metrics within a region of fiber crossing following axonal degeneration.

Micro-architectural characteristics of white matter can be inferred through analysis of diffusion-weighted magnetic resonance imaging (dMRI). The diffusion-dependent signal can be analyzed through several methods, with the tensor model being the most frequently used due to its straightforward interpretation and low requirements for acquisition parameters. While valuable information can be gained from the tensor-derived metrics in regions of homogeneous tissue organization, this model does not provide reliab...

Black carp PRMT6 inhibits TBK1-IRF3/7 signaling during the antiviral innate immune activation.

Protein arginine methylation is a prevalent posttranslational modification and protein arginine methyltransferases 6 (PRMT6) has been identified as a suppressor of TBK1/IRF3 in human and mammals. To explore the role of PRMT6 in teleost fish, PRMT6 homologue of black carp (Mylopharyngodon piceus) has been cloned and characterized in this study. Black carp PRMT6 (bcPRMT6) transcription in host cells varies in response to different stimuli and bcPRMT6 migrates around 43 kDa in the immunoblot assay. Like its ...

Is that move safe? Case study of cyclist movements at intersections with cycling discontinuities.

The cycling safety research literature has proposed methods to analyse safety and case studies to better understand the factors that lead to cyclist crashes. Surrogate measures of safety (SMoS) are being used as a proactive approach to identify severe interactions that do not result in an accident and interpreting them for a safety diagnosis. While most cyclist studies adopting SMoS have evaluated interactions by counting the total number of severe events per location, only a few have focused on the interac...

Development and characterization of a biomimetic coating for percutaneous devices.

Percutaneous osseointegrated prosthetics (POP), which consist of a metallic post attached to the bone that extends outward through the skin to connect to an external prosthesis, have become a clinically relevant option to replace the typical socket-residual limb connection. POP devices offer several advantages such as mechanical off-loading of soft tissues, direct force transfer to the musculoskeletal system, greater proprioception, and overall improvement in limb kinesis compared to a socket system. Howeve...

Characterization of previously identified novel DNA fragment associated with Pathogenicity Island III reveals new bla gene.

In the Kingdom of Bahrain a high percentage of extra-intestinal infectious diseases are reported as urinary tract infections UTIs. These UTIs are repeatedly diagnosed as multidrug resistant isolates. In a recent investigation, a novel DNA segment was identified in a UTI cefotaxime resistant Escherichia coli isolate. The DNA sequence was associated to pathogenicity island III locus. The current work is investigating/elucidating the genomic context of the newly identified locus in the UTI isolate using Single...


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