PubMed Journals Articles About "Varian Medical Systems Signs Brachytherapy Applicator Distribution Agreement" RSS

04:08 EDT 23rd June 2018 | BioPortfolio

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Showing "Varian Medical Systems Signs Brachytherapy Applicator Distribution Agreement" PubMed Articles 1–25 of 24,000+

Direction Modulated Brachytherapy (DMBT) Tandem Applicator for Cervical Cancer Treatment: Choosing the Optimal Shielding Material.

To investigate the dose modulation capability of a novel MRI-compatible Direction Modulated Brachytherapy (DMBT) tandem applicator design with various high density shielding materials for brachytherapy treatment of cervical cancer. The shield materials that have been evaluated are tantalum (Ta), pure tungsten (W), gold (Au), rhenium (Re), osmium (Os), platinum (Pt), iridium (Ir), and W' tungsten-alloy (95%W, 3.5%Ni, 1.5%Cu).

Normal tissue doses from MV image-guided radiation therapy (IGRT) using orthogonal MV and MV-CBCT.

The aim of this study was to measure and compare the mega-voltage imaging dose from the Halcyon medical linear accelerator (Varian Medical Systems) with measured imaging doses with the dose calculated by Eclipse treatment planning system.

Determining Optimal Eluter Design by Modeling Physical Dose Enhancement in Brachytherapy.

In-situ drug release concurrent with radiation therapy has been proposed to enhance the therapeutic ratio of permanent prostate brachytherapy. Both brachytherapy sources and brachytherapy spacers have been proposed as potential eluters to release compounds, such as nanoparticles or chemotherapeutic agents. The relative effectiveness of the approaches has not been compared yet. This work models the physical dose enhancement of implantable eluters in conjunction with brachytherapy to determine which delivery ...

Research and Implementation of Vital Signs Monitoring System Based on Cloud Platform.

Through analyzing the existing problems in the current mode, the vital signs monitoring information system based on cloud platform is designed and developed. The system's aim is to assist nurse carry out vital signs nursing work effectively and accurately. The system collects, uploads and analyzes patient's vital signs data by PDA which connecting medical inspection equipments. Clinical application proved that the system can effectively improve the quality and efficiency of medical care and may reduce medic...

EM-enhanced US-based seed detection for prostate brachytherapy.

Intraoperative dosimetry in low-dose-rate (LDR) permanent prostate brachytherapy requires accurate localization of the implanted seeds with respect to the prostate anatomy. Transrectal Ultrasound (TRUS) imaging, which is the main imaging modality used during the procedure, is not sufficiently robust for accurate seed localization. We present a method for integration of electromagnetic (EM) track-ing into LDR prostate brachytherapy procedure by fusing it with TRUS imaging for seed localization.

Mental Nerve Blocks for Lip Brachytherapy: A Case Report.

High dose rate interstitial brachytherapy is a commonly performed procedure for carcinoma of the lower lip. Placement of the brachytherapy catheters can be painful and may require monitored anesthesia care or general anesthesia. We present the use of bilateral mental nerve blocks with minimal sedation to facilitate placement of brachytherapy catheters.

Outcomes and Toxicities in Intermediate-Risk Prostate Cancer Patients Treated with Brachytherapy Alone or Brachytherapy and Supplemental External Beam Radiation Therapy.

To evaluate the cancer control outcomes and long-term treatment-related morbidity of brachytherapy as well as combination brachytherapy and EBRT in patients with intermediate-risk prostate cancer.

Can reference images improve interobserver agreement in reporting liver fibrosis?

Staging of fibrosis in medical liver biopsies has inherent interobserver variability. There are a number of disease-specific scoring systems available. While recognising the importance of these scoring systems, there is scope to consider how concordance amongst histopathologists could be improved using a generic fibrosis staging system.Using virtual slides, we approached both specialist liver histopathologists and general histopathologists from the UK to assess the degree of fibrosis against a proposed four...

A Medicare cost analysis of MRI- versus CT-based high-dose-rate brachytherapy of the cervix: Can MRI-based planning be less costly?

While some institutions deliver multiple fractions per implant for MRI-based planning, it is common for only one fraction to be delivered per implant with CT-based cervical brachytherapy. The purpose of this study was to compare physician costs, hospital costs, and overall costs for cervical cancer patients treated with either CT-based or MRI-based high-dose-rate (HDR) cervical brachytherapy to determine if MRI-based brachytherapy as described can be financially feasible.

Validation of MRI to TRUS registration for high-dose-rate prostate brachytherapy.

The objective of this study was to develop and validate an open-source module for MRI to transrectal ultrasound (TRUS) registration to support tumor-targeted prostate brachytherapy.

Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer: An institutional experience.

To evaluate the long-term disease control and toxicity to the organs at risk after dose-escalated image-based adaptive brachytherapy (BT) in cervical cancer.

Dosimetric study of GZP6 Co high dose rate brachytherapy source.

The purpose of this study was to obtain dosimetric parameters of GZP6 Co brachytherapy source number 3. The Geant4 MC code has been used to obtain the dose rate distribution following the American Association of Physicists in Medicine (AAPM) TG-43U1 dosimetric formalism. In the simulation, the source was centered in a 50 cm radius water phantom. The cylindrical ring voxels were 0.1 mm thick for r ≤ 1 cm, 0.5 mm for 1 cm  5 cm. The kerma-dose approximation was performed for r > 0.75 cm to inc...

Medical cyber-physical systems: A survey.

Medical cyber-physical systems (MCPS) are healthcare critical integration of a network of medical devices. These systems are progressively used in hospitals to achieve a continuous high-quality healthcare. The MCPS design faces numerous challenges, including inoperability, security/privacy, and high assurance in the system software. In the current work, the infrastructure of the cyber-physical systems (CPS) are reviewed and discussed. This article enriched the researches of the networked Medical Device (MD)...

Principles and Practice of HDR Penile Brachytherapy: Planning and Delivery Techniques.

To allow for organ preservation, high dose rate brachytherapy may be used in the treatment of localized penile cancer. Penile cancer is a rare malignancy, accounting for less than one percent of cancers in men in the United States. The standard treatment for localized disease is partial amputation of the penis. However, patients with T1b or T2 disease, less than 4 cm in maximum dimension and confined to the glans penis may be treated with brachytherapy as an organ-sparing approach. Previous works have descr...

The role of (125)I interstitial brachytherapy for inoperable parotid gland carcinoma.

The treatment of inoperable parotid gland carcinoma is challenging and controversial. The purpose of this paper was to present our experience in treating this malignancy using (125)I interstitial brachytherapy.

Plaque brachytherapy for posterior uveal melanoma in 2018: improved techniques and expanded indications.

Plaque brachytherapy remains the dominant globe-sparing therapy of uveal melanoma. This report highlights recent advances, which have expanded plaque brachytherapy's uses as well as improved the surgical technique.

Porosity of flowable resin composites is not influenced by applicator tip diameter.

To assess the influence of applicator tip diameter on the inclusion of porosities in three different flowable resin composites.

A customized approach for arm fat reduction using cryolipolysis.

Cryolipolysis of the arms has been demonstrated to be an effective treatment for non-invasive reduction of subcutaneous fat. This study evaluated the safety and efficacy of the concurrent use of a new commercially-available small applicator in conjunction with an existing medium sized applicator for the customized treatment of arm fat.

Why is brachytherapy still essential in 2017?

These recent years, brachytherapy has benefited from imaging modalities advances. A more systematic use of tomodensitometric, ultrasonographic and MRI images during brachytherapy procedures has allowed an improvement in target and organs at risk assessment as well as their relationship with the applicators. New concepts integrating tumor regression during treatment have been defined and have been clinically validated. New applicators have been developed and are commercially available. Optimization processes...

Initial experience with intraoperative phosphorous-32 brachytherapy during resection of malignant spinal tumors.

Brachytherapy is a major adjuvant modality for neoplasms, but few have trialed its use for spinal tumors. This study examines perioperative and oncological outcomes of malignant spinal tumor patients who underwent resection with intraoperative phosphorous-32 (P32) brachytherapy.

Quality of Life After High-dose Brachytherapy in Patients with Early Oral Carcinoma.

The prevalence of head and neck tumors has continually increased over the past decades, which is a serious medical and social problem. This study retrospectively assessed the quality of life of patients with early-stage oral cavity tumors after high-dose rate (HDR) brachytherapy.

Comments on "Low-dose-rate prostate brachytherapy: 4-8 week postimplant prostate-specific antigen a novel predictor of biochemical failure-free survival".

Manual vs. automated implantation of seeds in prostate brachytherapy: Oncologic results from a single-center study.

The objective of this study was to study survival and tolerance of prostate cancer patients treated with (125)I permanent interstitial brachytherapy by automated vs. manual implantation of seeds.

Surgical ward nurses' responses to worry: An observational descriptive study.

Rapid response systems aim to improve early recognition and treatment of deteriorating general ward patients. Sole reliance on deviating vital signs to escalate care in rapid response systems disregards nurses' judgments about a patient's condition based on worry and other indicators of deterioration. To make worry explicit, the Dutch-Early-Nurse-Worry-Indicator-Score was developed, summarising non-quantifiable signs of deterioration in the nine indicators: breathing, circulation, temperature, mentation, ag...

Microdosimetric Evaluation of Current and Alternative Brachytherapy Sources-A Geant4-DNA Simulation Study.

Radioisotopes such as (75)Se, (169)Yb, and (153)Gd have photon energy spectra and half-lives that make them excellent candidates as alternatives to (192)Ir for high-dose-rate brachytherapy. The aim of the present study was to evaluate the relative biological effectiveness (RBE) of current ((192)Ir, (125)I, (103)Pd) and alternative ((75)Se, (169)Yb, (153)Gd) brachytherapy radionuclides using Monte Carlo simulations of lineal energy distributions.

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