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Vocera Earns From Department Defense PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Vocera Earns From Department Defense articles that have been published worldwide.
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Microbes exist in a constant struggle with viruses and have evolved multiple defense mechanisms. Some of these, such as restriction endonucleases and CRISPR-Cas, have revolutionized genome editing methodology. A systematic strategy combining computation and experiment led to discovery of ten new defense systems that remain to be characterized mechanistically.
Recent clinical practice guidelines from major national organizations, including a joint United States Department of Veterans Affairs (VA) and Department of Defense (DoD) committee, have substantially changed recommendations for the use of the cholesterol-lowering statin medications after years of relative stability. Because statin medications are among the most commonly prescribed treatments in the United States, any change in their use may have significant implications for patients and providers alike. Pr...
In this issue of Molecular Cell, Penn et al. (2018) report the protein interactome between Mycobacterium tuberculosis (Mtb) secreted effectors and macrophage cytosolic proteins. This Resource reveals that the interaction of Mtb effector LpqN with host CBL counteracts antibacterial defense but causes a reciprocal enhancement of antiviral defense.
Emergency department nurses are faced with an overwhelming number of patients each day. The average number of emergency department visits is increasing by 3.5% per year. Numerous studies have been conducted to improve the patient throughput process, which has impact on patient flow. A disruption of the process can cause a backlog of patients and create a hardship for both patients and staff.
Emergency department (ED) crowding is common and associated with increased costs and negative patient outcomes. The aim of this study was to conduct an in-depth analysis to identify the root causes of an ED length of stay (ED-LOS) of more than six hours.
We review the published literature over the last 24 months in the treatment of PTSD for our military men and women. We examined the updated clinical practice guidelines published in June 2017 by the Veteran's administration and Department of Defense and contrasted the guidelines with the most recent literature. We also discuss new directions in PTSD research.
Microbial defense systems provide fundamental elements for biotechnology development. For example, molecular cloning techniques greatly depend on the discovery of the bacterial restriction-modification system, and similarly, deciphering the CRISPR adaptive immunity gives rise to the revolutionary genome editing technique CRISPR-Cas9. Therefore, exploring novel microbial defense systems has attracted world-wide attention, and new systems like prokaryotic Argonautes (pAgos) and the defense island system assoc...
The Department of Veterans Affairs (VA) amends its regulation to provide for reimbursement of qualifying adoption expenses incurred by a veteran with a service-connected disability that results in the inability of the veteran to procreate without the use of fertility treatment. Under the Continuing Appropriations and Military Construction, Veterans Affairs, and Related Agencies Appropriations Act, 2017, and Zika Response and Preparedness Act, VA may use funds appropriated or otherwise made available ...
Plant peptides secreted as signal molecular to trigger cell-to-cell signaling are indispensable for plant growth and defense processes. Preciously, it is regraded some plant peptides function in plant growth and development, whereas others regulate defense response in plant-microbe interactions. However, this prejudice is got rid due to more and more evidence showed growth-related plant peptides also exhibit bifunctional roles in plant defense response against different microbial pathogens. Here we provide ...
Prior research suggests that uncertainty related to symptoms is a driver of emergency department (ED) use, and that patients often leave the ED with uncertainty not being addressed. Our objective was to engage patients to identify domains that contribute to feelings of uncertainty and decisions to use the ED.
Vertigo is a common symptom and reason for admission to the emergency department (ED).
Identifying patients with sepsis at triage can lead to a decrease in door-to-antibiotic time. Our community hospital emergency department's mean door-to-antibiotic time was 105.3 minutes, falling short of the Surviving Sepsis Campaign guideline's benchmark goal of 60 minutes. One of the most common reasons for treatment delays was that patients with sepsis were not identified upon entrance to the emergency department. A solution to the delay was to implement a practice improvement project by having the tr...
A prototype ecological interface for computer network defense (CND) was developed.
Rhinovirus is a leading cause of acute respiratory infections and asthma attacks, but infections are also frequently cleared from the nasal mucosa without causing symptoms. We sought to better understand host defense against rhinovirus by investigating antiviral defense in primary human nasal and bronchial airway epithelial cells cultured ex vivo. Surprisingly, upon rhinovirus infection or RIG-I stimulation, nasal-derived epithelial cells exhibited much more robust antiviral responses than bronchial-derive...
The phytohormone 7-iso-(+)-jasmonoyl-L-isoleucine (JA-Ile) mediates plant defense responses against herbivore and pathogen attack, and thus increases plant resistance against foreign invaders. However, JA-Ile also causes growth inhibition; and therefore JA-Ile is not a practical chemical regulator of plant defense responses. Here, we describe the rational design and synthesis of a small molecule agonist that can upregulate defense-related gene expression and promote pathogen resistance at concentrations tha...
Emergency department crowding is a major global healthcare issue. There is much debate as to the causes of the phenomenon, leading to difficulties in developing successful, targeted solutions.
Pediatric Early Warning Scores were developed to monitor clinical deterioration of children admitted to the hospital. Pediatric Early Warning Scores could also be useful in the Emergency Department to quickly identify critically ill patients so treatment can be started without delay. To determine if a newly designed, fast, and easy to use Modified Pediatric Early Warning Score can identify critically ill children in the Emergency Department. We conducted a retrospective observational study in the Emergency ...
Despite sufficient literature analyzing macroscopic and microscopic methods of addressing emergency department (ED) operations, there is a paucity of studies that analyze methods between these extremes.
Hypoglycemia associated to insulin or other glucose-lowering agents is one of the most common causes of visits to the emergency department for adverse drug reactions. The study objective was to analyze the characteristics of patients with diabetes mellitus (DM) who attend a tertiary hospital emergency department for a hypoglycemic event.
Colorectal cancer (CRC) is the leading cause of cancer deaths in Europe. Survival is poorer in patients admitted to hospitals through the emergency department than in electively admitted patients. Knowledge of factors associated with a cancer diagnosis through presentation at an emergency department may reduce the likelihood of an emergency diagnosis. This study evaluated factors influencing the diagnosis of CRC in the emergency department.
The goal of this project was to decrease handoff delays from the emergency department (ED) as measured by ready to move (RTM)-to-occupied time.
The mission of the Department of Defense Birth and Infant Health Registry (Registry) is to conduct ongoing surveillance of birth defects among military families, following the National Birth Defects Prevention Network (NBDPN) case definitions. From 2009 to 2011, a 30% increase in diagnoses of obstructive genitourinary defects (OGDs) was observed in the Registry. To explore the source of this finding, we identified the location with the highest increase and conducted a validation study for OGD cases.