PubMed Journals Articles About "Player Steve Gleason Given Congressional Gold Medal Work" RSS

22:35 EST 16th February 2020 | BioPortfolio

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Showing "player Steve Gleason given Congressional Gold Medal work" PubMed Articles 1–25 of 12,000+

Mortality-to-incidence ratios by US Congressional District: Implications for epidemiologic, dissemination and implementation research, and public health policy.

The mortality-to-incidence ratio (MIR) can be computed from readily accessible, public-use data on cancer incidence and mortality, and a high MIR value is an indicator of poor survival relative to incidence. Newly available data on congressional district-specific cancer incidence and mortality from the U.S. Cancer Statistics (USCS) database from 2011 to 2015 were used to compute MIR values for overall (all types combined), breast, cervix, colorectal, esophagus, lung, oral, pancreas, and prostate cancer. Con...

Reflections on Randomized Trials and Observational Studies: "Big Is Beautiful" A Conversation With Sir Rory Collins, FRS.

Rory Collins is the Head, Nuffield Department of Population Health, University of Oxford, Principal Investigator and Chief Executive, UK Biobank, and the British Heart Foundation Professor of Medicine and Epidemiology at the University of Oxford. He was born in Hong Kong and received his medical degree from St Thomas's Hospital Medical School, University of London. He was Knighted for Services to Science in 2011 and became a Fellow of the Royal Society in 2015. He has delivered the Paul Dudley White Interna...

A policy mapping analysis of goals, target populations, and punitive notions in the U.S. congressional response to the opioid epidemic.

The U.S. Congress has proposed numerous bills and resolutions in response to the opioid epidemic unfolding over the past decade. Although this legislative response has been the subject of considerable media attention and commentary, very little research has systematically analyzed congressional opioid-related legislation in terms of primary goals, focal populations, and the extent to which it includes punitive mechanisms.

Overall, specific, and metastasis-free survival of Afro-Caribbean men with pathological Gleason 6 prostate cancer.

Several studies in the Caucasian population have shown that patients with Gleason 6 prostate cancer, based on surgical specimens, have low or no risk of metastasis. However, there is no data for men of African ancestry. The objective of this study was to estimate the overall, specific, and metastasis-free survival (MFS) of patients with a Gleason 6 score, based on the surgical specimen.

Evolution of prostate cancer histopathology.

During the last 15 years several updates in the Gleason grading have been made. With the help of pertinent research results pathologists have gained a better insight into the meanings of several prostate cancer (PCa) patterns and know better how to classify them in the Gleason grade system.

Proportion of cores with the highest Gleason grade group among positive cores on prostate biopsy: does this affect the probability of upgrading or downgrading?

This study assessed the ability to predict the probability of pathologic upgrading or downgrading based on the proportion of cores with the highest Gleason grade on prostate biopsy. From 2002-2017, 494 patients with multiple positive cores on prostate biopsy who underwent radical prostatectomy were included for the analysis. The proportion of cores with the highest Gleason grade group among positive cores was calculated and patients were divided into three groups based on the proportion (≤33% vs >33% and ...

Marine mammal vet's dedication marked by prestigious award.

Vet pathologist has been awarded the ZSL Silver Medal for his outstanding work in the field of wildlife conservation involving marine mammals. Jan Loveridge explains why the award is so well deserved.

Comparing subjective and objective evaluations of player performance in Australian Rules football.

Player evaluation plays a fundamental role in the decision-making processes of professional sporting organisations. In the Australian Football League, both subjective and objective evaluations of player match performance are commonplace. This study aimed to identify the extent to which performance indicators can explain subjective ratings of player performance. A secondary aim was to compare subjective and objective ratings of player performance. Inside Football Player Ratings (IFPR) and Australian Football...

Expression of stromal elements of prostatic adenocarcinoma in different gleason scores.

To quantify and compare the expression of stromal elements in prostate adenocarcinoma of different Gleason scores with non-tumor area (control).

Maladaptive player-game relationships in problematic gaming and gaming disorder: A systematic review.

While certain player vulnerabilities are known to increase risk of gaming disorder (GD), the topic of maladaptive player × game relationships in GD has received limited attention. This review aimed to: (1) identify game types associated with GD symptomatology; and (2) evaluate individual differences (e.g., age, personality, depression) in the relationship between gaming and GD symptomatology. A systematic review of six databases identified 23 studies of the relations between game types and GD, includin...

DNA Origami Catenanes Templated by Gold Nanoparticles.

Mechanically interlocked molecules have marked a breakthrough in the field of topological chemistry and boosted the vigorous development of molecular machinery. As an archetypal example of the interlocked molecules, catenanes comprise macrocycles that are threaded through one another like links in a chain. Inspired by the transition metal-templated approach of catenanes synthesis, the hierarchical assembly of DNA origami catenanes templated by gold nanoparticles is demonstrated in this work. DNA origami cat...

Association of statin use with risk of Gleason score-specific prostate cancer: A hospital-based cohort study.

Conflicting evidence suggests that statins act chemopreventively against prostate cancer (PCa). Whether the association of statin use with PCa risk is Gleason score-dependent, time-, dose-respondent is not well studied.

Gold-catalyzed Iminations of Terminal Propargyl Alcohols with Anthranils with Atypical Chemoselectivity for C(1)-Additions and 1,2-Carbon Migration.

This work reports gold-catalyzed iminations of terminal propargyl alcohols with anthranils or isoxazoles to yield E-configurated α-amino-2-en-1-ones and -1-als with complete chemoselectivity. These catalytic iminations occur exclusively with the C(1)-nucleophilic additions on terminal alkynes, in contrast to a typical C(2)-route.  For 3,3-dialkylprop-1-yn-3-ols, a methyl substituent is superior to long alkyl chains as the 1,2-migration groups toward α-imino gold carbenes. For secondary prop-1-yn-3-ols, p...

Correlations between Apparent Diffusion Coefficient and Gleason Score in Prostate Cancer: A Systematic Review.

Reported data regarding the associations between apparent diffusion coefficient (ADC) of diffusion-weighted imaging (DWI) and Gleason score in prostate cancer (PC) are inconsistent.

Comparison of screening tests without a gold standard - a pragmatic approach with virtual reference testing.

Well-defined diagnostic gold standards are rarely available for the diagnosis of rare diseases such as some tropical infections. Algorithms for reliable test evaluation without gold standard are therefore desirable. On the basis of previous work of Gart & Buck (1966), Rogan & Gladen (1978), and Hui & Walter (1980), a modeling approach for the comparison of diagnostic tests without a gold standard - and thus without reliably characterized reference sample material - is established especially for situations n...

Gold-Catalyzed Silyl-Migrative Cyclization of Homopropargylic Alcohols Enabled by Bifunctional Biphenyl-2-ylphosphine and DFT Studies.

The development of novel ligands specifically tailored for homogeneous gold catalysis permits the development of new gold catalysis. In this work, we report that a remotely functionalized biphenyl-2-ylphosphine ligand enables gold-catalyzed cyclization of homopropargylic alcohols accompanied by an unusual silyl migration, which provides efficient access to 3-silyl-4,5-dihydrofurans. DFT studies of the mechanism of this novel transformation suggest the synergy between the steric bulk of the ligand and its pr...

The German Society for Social Medicine and Prevention (DGSMP) confers the Salomon Neumann Medal for outstanding merit in the field of Preventive and Social Medicine. The Salomon Neumann Medal 2017 was awarded to Gerhard Trabert, founder and chairman of the association "Poverty and Health in Germany" and professor for social medicine und social psychiatry at the RheinMain University of applied sciences in Wiesbaden. It honours a physician in the field of social medicine, whose personality and activity as "do...

CVIR Editors' Medal 2019.

Gleason score 5+3=8 (grade group 4) prostate cancer - a rare occurrence with contemporary grading.

Grade Group (GG) 4 prostate cancer includes Gleason scores (GS) 3+5=8, 4+4=8, and 5+3=8. Some studies without pathology re-review of historical cohorts proposed that the presence of pattern 5 worsens prognosis compared to GS 4+4=8 cancer. We assessed how often historically graded GS 5+3=8 cancers retain this grade with contemporary grading recommendations. Sixteen prostate biopsies and 24 radical prostatectomies (RP) reported from 2005 to 2019 as GS 5+3=8 were re-reviewed and graded according to contemporar...

Nanoscale induced formation of silicide around gold nanoparticles encapsulated in a-Si.

Decorating thin film solar cells with plasmonic nanoparticles is being pursued, in order to improve device efficiency through increased scattering and local field enhancement. Gold nanoparticles are in particular interesting, due to their chemical inertness and plasmon resonance in the visible range of the spectrum. In this work, gold nanoparticles fabricated by a gas aggregation nanoparticle source and embedded in a-Si (a commercial solar cell material) are studied using x-ray photo-electron spectroscopy, ...

What Medical Students Teach: The Healing Skill of Being a Team Player.

The question, what makes a clinician a healer? may evoke the image of a devoted physician paying a critically important home visit at the end of a long day or the image of an astute nurse-steadfast, empathic, anticipating the patient's needs before they become apparent to others. But health care is no longer provided by lone doctors or nurses. In the modern health care system, multiple professionals must work together to provide safe and effective care. The moral nature of healing has not changed. But what ...

Prevalence Of Positive Quantiferon-Tb Gold In-Tube Test In Uveitis And Its Clinical Implications In A Country Non-Endemic For Tuberculosis.

To report on the prevalence and clinical implications of positive QuantiFERON-Gold (QFT-G) test results in the diagnostic work-up of a large cohort of consecutive patients with uveitis in the Netherlands.

Blue luminescent graphene quantum dot conjugated cysteamine functionalized-gold nanoparticles (GQD-AuNPs) for sensing hazardous dye Erythrosine B.

Erythrosine B (ErB) is a xanthenes approved dye that widely used in various fields such as foods, drugs and cosmetics. This work intended to analyze the interaction of this dye on synthesized graphene quantum dot conjugated cysteamine functionalized gold nanoparticles. Pyrolysis of citric acid was applied to graphene quantum dots (GQDs) synthesis. These are zero dimensional materials promising considerable applications because of their extraordinary physicochemical properties. In this work, to improve its a...

Structural Characterization of a Gold/Serum Albumin Complex.

The medicinal gold(III) dithiocarbamato complex AuL forms a stable adduct with bovine serum albumin. The crystal structure reveals that a single gold(I) center is bound to Cys34, with the dithiocarbamato ligand being released. To the best of our knowledge, this is the first structure for a gold adduct of serum albumin.

Isomerization in Alkynyl-Protected Gold Nanoclusters.

We report the controlled synthesis and total structure of two isomeric gold nanoclusters, whose compositions were determined to be Au23(C≡CBut)15 (denoted as Au23-1 and Au23-2) by single-crystal X-ray diffraction and matrix-assisted laser desorption ionization-time of flight-mass spectrometry (MALDI-TOF-MS). This is the first time to discover isomerism in alkynyl-protected gold nanoclusters. The metal-to-ligand ratios in these two clusters are different from known Aun(SR)m systems and have not been observ...

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