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PubMed Journals Articles About "Scientists Develop Laboratory Model Study Tickborne Flaviviruses" RSS

23:09 EDT 19th September 2018 | BioPortfolio

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Showing "scientists develop laboratory model study tickborne flaviviruses" PubMed Articles 1–25 of 76,000+

Laboratory Model of a Collapsible Tube to Develop Bleeding Control Interventions.

To develop knowledge of mechanical control of bleeding in first aid, a laboratory model was set up to simulate flow through a blood vessel. A collapsible tube was used to mimic an artery in two experiments to determine (1) the extent of volumetric flow reduction caused by increases in the degree of compression of the vessel and (2) the extent of flow reduction caused by increases in the length of compression.


Development of a saphenous vein harvest model for simulation-based assessment.

There is a need to develop a realistic model of open saphenous vein harvesting for simulation training and assessment. The purpose of this study was to develop a novel simulated model of this procedure and to examine its viability by examining participants' performance and feedback on this model.

Career Satisfaction in the Profession of Medical Laboratory Science.

The purpose of this research was to determine which job features create motivation and career satisfaction to retain personnel in the medical laboratory profession. Four research questions based on Wlodkowski's theory of motivation guided the study: Is there a difference in perceived career satisfaction among medical laboratory scientists who: a) feel included by practitioners in other healthcare professions, b) have choices on the job that are personally relevant, c) feel more challenged, and d) feel more ...


Body Fluid Processing Workspace Quality Improvement Initiative in a High-Volume Reference Laboratory.

In a clinical laboratory, the design of the workspace directs the workflow and significantly affects the productivity of clinical laboratory scientists (CLS). With the chronic shortage of CLS, a well-designed workspace is essential to take full advantage of available staff, especially in high-volume laboratories.

Tickborne Diseases - Confronting a Growing Threat.

Biochemistry and Molecular Biology of Flaviviruses.

Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile, yellow fever, and Zika viruses, are critically important human pathogens that sicken a staggeringly high number of humans every year. Most of these pathogens are transmitted by mosquitos, and not surprisingly, as the earth warms and human populations grow and move, their geographic reach is increasing. Flaviviruses are simple RNA-protein machines that carry out protein synthesis, genome replication, and virion packaging...

Detection of Arbovirus Transmission via Sugar Feeding in a Laboratory Setting.

Most species of mosquitoes consume sugar to survive and during sugar feeding can expectorate virus. Scientists have used this behavior to develop novel methods of mosquito control and arbovirus surveillance. In this study, we use sugar feeding and corresponding viral expectoration to develop an affordable method of monitoring individual mosquitoes for longitudinal data collection. Female Culex tarsalis Coquillett (Diptera: Culicidae) that consumed an infectious bloodmeal of West Nile virus were placed into ...

Making Waves: New Developments in Toxicology with the Zebrafish.

The laboratory zebrafish (Danio rerio) is now an accepted model in toxicologic research. The zebrafish model fills a niche between in vitro models and mammalian biomedical models. The developmental characteristics of the small fish are strategically being used by scientists to study topics ranging from high-throughput toxicity screens to toxicity in multi- and transgenerational studies. High-throughput technology has increased the utility of zebrafish embryonic toxicity assays in screening of chemicals and ...

Ilheus and Saint Louis encephalitis viruses elicit cross-protection against a lethal Rocio virus challenge in mice.

Rocio virus (ROCV) was the causative agent of an unprecedented outbreak of encephalitis during the 1970s in the Vale do Ribeira, Sao Paulo State, in the Southeast region of Brazil. Surprisingly, no further cases of ROCV infection were identified after this outbreak; however, serological surveys have suggested the circulation of ROCV among humans and animals in different regions of Brazil. Cross-protective immunity among flaviviruses is well documented; consequently, immunity induced by infections with other...

Dental age estimation in Somali children using the Willems et al. model.

The aim of the current study was to retrospectively collect dental panoramic radiographs from Somali children living in Finland, to use the radiographic data to develop a new age estimation model based on the model established by Willems et al. (J Forensic Sci 46(4):893-895, 2001), and to compare the age prediction performances of the Willems et al. model (WM) and the newly developed model.

Multivariate Model for the Prediction of Severity of Acute Pancreatitis in Children.

This study aimed to develop a severity prediction system for pediatric patients with acute pancreatitis (AP) based on clinical and laboratory parameters recorded at disease onset. A retrospective cohort study including 130 patients with AP, aged 0 to 18 years, was conducted. Correlations between severe AP (SAP) and clinical and laboratory data were established. Parameters with a significant statistical correlation (P ≤ 0.05) were incorporated in logistic regression models, and receiver operating chara...

Building flux capacity: Citizen scientists increase resolution of soil greenhouse gas fluxes.

Though citizen science programs have been broadly successful in diverse scientific fields, their adoption has lagged in some disciplines, including soil science and ecosystem ecology. Collaborations with citizen scientists may be viewed as a conundrum in these disciplines, which often require substantial labor and technical experience; citizen scientists could improve sampling capacity but may reduce sample quality or require training and oversight prior to and while performing specialized tasks. To demonst...

Narrative and "anti-narrative" in science: How scientists tell stories, and don't.

Narratives are common to all branches of science, not only to the humanities. Scientists tell stories about how the things we study work, develop, and evolve, and about how we come to be interested in them. Here I add a third domain (Secularity) to Gould's two "non-overlapping magisteria" of Science and Religion, and I review previous work on the parallels in elements between story-telling in literature and science. The stories of each domain have different criteria for judging them valid or useful. In scie...

The use of the chick embryo chorioallantoic membrane as experimental model to study virus growth and to test the clonal selection hypothesis. The contribution of Sir Mac Farlane Burnet.

Sir Mac Farlane Burnet was the most honored of all Australian scientists. In 1960, Burnet shared the Nobel Prize for Medicine with Peter Medawar of Britain for the discovery of acquired immunological tolerance, He developed techniques for growing influenza viruses in the chorioallantoic membrane of the chick embryo. This became standard laboratory practice. He continued to work with chick embryos long after the use of cell cultures had become general. His virology research resulted in significant discoverie...

Young scientists and Clinical Biochemists need to develop superior negotiating skills.

Beyond the Brown Bag: Designing Effective Professional Development for Informal Educators.

Most researchers are keenly interested in disseminating their work beyond traditional publication routes. With an eye to increasing broader impacts, scientists can benefit from partnerships with informal educators who interact daily with the public and see their role as translating science to increase the public's intellectual and emotional connections with the natural world. Typically, researchers give a one-time lunch hour talk, generally a modified version of a presentation aimed at scientific peers. Tal...

A Clinical Model for the Early Diagnosis of Acute Pancreatitis in the Emergency Department.

This study aimed to develop a diagnostic model that predicts acute pancreatitis (AP) risk before imaging.

A new laboratory-based algorithm to predict microvascular invasion and survival in patients with hepatocellular carcinoma.

Preoperative serum inflammatory markers have been correlated with survival outcomes after resection of hepatocellular carcinoma (HCC). Whether they can predict microvascular invasion (MVI) in HCC is still unknown. This study aimed to evaluate the association of inflammatory markers with MVI, and develop a simple and inexpensive preoperative prediction model for MVI.

Gender Comparison of Medical Student Microsurgical Skills in a Laboratory Model.

 Perceived gender-related differences in surgical skills could limit opportunities available for any aspiring surgeon. There should be more available literature and logical analysis of these observations. The objective of this study is to evaluate the microsurgical skills of male and female medical students using a standard scale in the laboratory.

Development of a statistical model for cervical cancer cell death with irreversible electroporation in vitro.

The aim of this study was to develop a statistical model for cell death by irreversible electroporation (IRE) and to show that the statistic model is more accurate than the electric field threshold model in the literature using cervical cancer cells in vitro.

Evaluation of Percutaneous Intradiscal Amniotic Suspension Allograft in a Rabbit Model of Intervertebral Disc Degeneration.

Laboratory study using a rabbit annular puncture model of intervertebral disc degeneration (IDD).

Improvement and application of the PCPF-1@SWAT2012 model for predicting pesticide transport: A case study of the Sakura River watershed.

The PCPF-1@SWAT model was previously developed to simulate the fate and transport of rice pesticide in watersheds. However, the current model is deficient in characterize the rice paddy area and is incompatible with the ArcSWAT2012 program. In this study, we modified original PCPF1@SWAT model to develop new PCPF1@SWAT2012 model to address the deficiency of rice paddy area and utilizing the ArcSWAT2012 program. Next, the new model was applied in Sakura River watershed, Ibaraki, Japan in order to simulate the...

History of the Development of Anesthesia for the Dolphin: A Quest to Study a Brain as Large as Man's.

It is important for academic-minded human anesthesiologists to have an interdisciplinary perspective when engaging in cutting-edge research as well as the practice of human anesthesiology. This was a philosophy promoted by Dr. Robert Dripps, former pioneering Chairman of the Anesthesiology Department at the University of Pennsylvania (Philadelphia, Pennsylvania). Many human and veterinary anesthesiologists as well as biomedical engineers and neuroscientists benefited from Dr. Dripps's constructive outlook p...

The Enduring Influence of a Dangerous Narrative: How Scientists Can Mitigate the Frankenstein Myth.

Reflecting the dangers of irresponsible science and technology, Mary Shelley's Frankenstein quickly became a mythic story that still feels fresh and relevant in the twenty-first century. The unique framework of the Frankenstein myth has permeated the public discourse about science and knowledge, creating various misconceptions around and negative expectations for scientists and for scientific enterprises more generally. Using the Frankenstein myth as an imaginative tool, we interviewed twelve scientists to ...

Communications principles for inviting inquiry and exploration through science and data visualization.

Science, in the popular imagination, is about finding answers to questions. Scientists make discoveries, develop theories, and deliver those discoveries and theories to audiences with an interest in the truth as backed up by science. Well-designed data visualization (dataviz), by contrast, can generate and address not only new questions but new kinds of questions. It has the particular quality of allowing its viewers, users and makers the ability to generate new inquiries, and to put them in a better place ...


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