Topics

PubMed Journals Articles About "Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder" RSS

01:28 EDT 22nd August 2019 | BioPortfolio

Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder articles that have been published worldwide.

More Information about "Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder" on BioPortfolio

We have published hundreds of Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder news stories on BioPortfolio along with dozens of Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder Clinical Trials and PubMed Articles about Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder Companies in our database. You can also find out about relevant Abnormal Resting State Regional Homogeneity Unmedicated Bipolar Disorder Drugs and Medications on this site too.

Showing "Abnormal resting state regional homogeneity unmedicated bipolar disorder" PubMed Articles 1–25 of 16,000+

Osteogenesis imperfecta in Brazilian patients.

Osteogenesis Imperfecta (OI) is a heterogeneous genetic disorder characterized by bone fragility and fracture. Mutations in 20 distinct genes can cause OI, and therefore, the genetic diagnosis of OI is frequently difficult to obtain because of the great number of genes that can be related with this disease. Studies that report the most frequently mutated genes in OI patients can help to improve molecular strategies for diagnosis of the disease. In order to characterize the mutation profile of OI in Brazilia...


PROVISIONAL Birth defects in Brazil: Outcomes of a population-based study.

Birth defects (BDs) are functional and structural alterations in embryonic or fetal development. With an incidence of approximately 3-5%, BDs are a leading cause of infant mortality and lifelong disability. A population-based prospective case-control study was conducted for one year with 5204 infants, between 1st March 2011 and 29th February 2012, in the city of São José do Rio Preto, State of São Paulo, Brazil. The incidence of BDs was 3.2% [95% confidence interval (95% CI): 2.8-3.8%]. The most common c...

Biogeographical patterns in soil bacterial communities across the Arctic region.

The considerable microbial diversity of soils, their variety and key role in biogeochemical cycling has led to growing interest in their global distribution and the impact that environmental change might have at the regional level. In the broadest study of Arctic soil bacterial communities to date, we used high-throughput DNA sequencing to investigate the bacterial diversity from 200 independent Arctic soil samples from 43 sites. We quantified the impact of spatial and environmental factors on bacterial com...


Effect of Continuing Olanzapine vs Placebo on Relapse Among Patients With Psychotic Depression in Remission: The STOP-PD II Randomized Clinical Trial.

Psychotic depression is a severely disabling and potentially lethal disorder. Little is known about the efficacy and tolerability of continuing antipsychotic medication for patients with psychotic depression in remission.

Diagnostic challenge in a man with intractable hiccups and vomiting: a case of neuromyelitis optica spectrum disorder (NMOSD).

Neuromyelitis optica is an inflammatory CNS syndrome that is associated with serum aquaporin-4 immunoglobulin G antibodies (AQP4-IgG). According to the new diagnostic criteria the term NMO is replaced by the term NMOSD and for the first time criteria allow diagnosis in patients who have not experienced clinical involvement of either optic nerves or spinal cord. Area postrema, the emetic reflex center, may be a selective target of the disease. We report a case of a 74-year-old man who presented with intracta...

Light-inducible flux control of triosephosphate isomerase on glycolysis in Escherichia coli.

An engineering tool for controlling flux distribution on metabolic pathways to an appropriate state is highly desirable in bio-production. An optogenetic switch, which regulates gene expression by light illumination is an attractive on/off switchable system, and is a promising way for flux control with an external stimulus. We demonstrated a light-inducible flux control between glycolysis and the methylglyoxal (MGO) pathway in Escherichia coli using a CcaS/CcaR system. CcaR is phosphorylated by green light ...

Escherichia coli 'TatExpress' strains export several g/L human growth hormone to the periplasm by the Tat pathway.

Escherichia coli is a heavily used platform for the production of biotherapeutic and other high-value proteins, and a favoured strategy is to export the protein of interest to the periplasm in order to simplify downstream processing and facilitate disulphide bond formation. The Sec pathway is the standard means of transporting the target protein but it is unable to transport complex or rapidly folding proteins because the Sec system can only transport proteins in an unfolded state. The Tat system also opera...

Zero-Balance Ultrafiltration of the Priming Blood Modifies the Priming Components and Improves the Clinical Outcome in Infants Undergoing Cardiopulmonary Bypass: A Randomized Controlled Trial.

Cardiopulmonary bypass (CPB) requirement in infants presents a unique challenge because of the large prime volume-to-blood volume ratio. Packed red blood cells (PRBCs) tend to deteriorate with long-term storage owing to their unphysiological composition and osmolality. Given that blood priming is inevitable in neonates, it is suggested that the metabolic load and osmolality be diminished before CPB initiation. We conducted the present study to test the hypothesis that the zero-balance ultrafiltration (Z-BUF...

Benchmarking Treatment Effectiveness of Community-Delivered Trauma-Focused Cognitive Behavioral Therapy.

It is critical for urban youth with post-traumatic stress disorder (PTSD) living in poverty to have access to evidence-based interventions for their traumatic stress. However, there is limited research on the effectiveness of these interventions when provided in urban, community settings. The objectives of the current study are to (a) evaluate the effectiveness of trauma-focused cognitive behavioral therapy delivered from 2013 to 2016 in 15 behavioral health agencies on youth (N = 114) PTSD as well as  g...

When No One Notices: Disorders of Consciousness and the Chronic Vegetative State.

On January 5, 2019, the Associated Press reported that a woman thought to have been in the vegetative state for over a decade gave birth at a Hacienda HealthCare facility. Until she delivered, the staff at the Phoenix center had not noticed that their patient was pregnant. The patient was also misdiagnosed. Misdiagnosis of patients with disorders of consciousness in institutional settings is more the norm than the exception. Misdiagnosis is also connected to a broad and extremely significant change in the u...

Bystander Ethics and Good Samaritanism: A Paradox for Learning Health Organizations.

In 2012, a U.S. Institute of Medicine report called for a different approach to health care: "Left unchanged, health care will continue to underperform; cause unnecessary harm; and strain national, state, and family budgets." The answer, they suggested, would be a "continuously learning" health system. Ethicists and researchers urged the creation of "learning health organizations" that would integrate knowledge from patient-care data to continuously improve the quality of care. Our experience with an ongoin...

Chinese media coverage of eating disorders: Disorder representations and patient profiles.

Eating disorders (EDs) are becoming more prevalent in China; however, no studies have been conducted to explore how Chinese media represented EDs, and how media representation of ED impacted public understanding of EDs. The aim of this study was to analyze articles about EDs in Chinese newspapers, and to identify any potential inaccuracies about EDs as represented in the media.

Effectiveness of the Intent to Complete and Intent to Attend Intervention to Predict and Prevent Posttraumatic Stress Disorder Treatment Drop Out Among Soldiers.

Active duty military service members have high dropout rates for trauma-focused treatment in both clinical practice and research settings. Measuring patients' intent to complete (ITC) and intent to attend (ITA) treatment have been suggested as methods to reduce dropout, but no studies have examined the effectiveness of such measures. In an attempt to reduce high dropout rates, measures of ITC and ITA were included in a randomized controlled trial evaluating prolonged exposure (PE) and virtual reality exposu...

Widespread higher fractional anisotropy associates to better cognitive functions in individuals at ultra-high risk for psychosis.

In schizophrenia patients, cognitive functions appear linked to widespread alterations in cerebral white matter microstructure. Here we examine patterns of associations between regional white matter and cognitive functions in individuals at ultra-high risk for psychosis. One hundred and sixteen individuals at ultra-high risk for psychosis and 49 matched healthy controls underwent 3 T magnetic resonance diffusion-weighted imaging and cognitive assessments. Group differences on fractional anisotropy were test...

Posttraumatic Growth during Cognitive Behavioral Therapy for Posttraumatic Stress Disorder: Relationship to Symptom Change and Introduction of Significant Other Assessment.

Posttraumatic growth (PTG) may play a role in the treatment of posttraumatic stress disorder as it is supposed to have either beneficial or dysfunctional effects on treatment-related PTS symptom (PTSS) changes. This study examined whether cognitive behavioral therapy (CBT) for PTSD patients can foster PTG assessed by self-reports and reports from significant others. Forty-eight PTSD patients participating in trauma-focused CBT were assessed twice: at the beginning of therapy (T1) and after three months of t...

The molecular mechanism underlying GABAergic dysfunction in nucleus accumbens of depression-like behaviours in mice.

Depression is the most frequent psychiatric disorder in the world. Recent evidence has shown that stress-induced GABAergic dysfunction in the nucleus accumbens (NAc) contributed to the pathophysiology of depression. However, the molecular mechanisms underlying these pathological changes remain unclear. In this study, mice were constantly treated with the chronic unpredictable mild stress (CUMS) till showing depression-like behaviours expression. GABA synthesis, release and uptake in the NAc tissue were asse...

Lossless Compression of Cytometric Data.

Nowadays, most cytometrists apply lossless compression by storing their FCS files in ZIP archives. Unfortunately, ZIP only achieves modest space savings in cytometric data, due to DEFLATE being used as the underlying lossless compression algorithm (LCA). Presumably, other modern LCA can outperform DEFLATE, especially in terms of space savings. Twenty-one codecs (programs implementing LCA) were evaluated in 167,131 publicly available FCS files. Within floating-point data, as produced by modern instruments, m...

Characterizing TDP-43(307-319) Oligomeric Assembly : Mechanistic and Structural Implications Involved in the Etiology of Amyotrophic Lateral Sclerosis.

Aggregation of TAR DNA-binding protein of 43kDa (TDP-43) is a salient feature for amyotrophic lateral sclerosis (ALS), a debilitating neurodegenerative disorder affecting over 200,000 people worldwide. The protein undergoes both functional and pathogenic aggregation; the latter is irreversible and hypothesized to produce soluble oligomers that are toxic to neurons in addition to inclusions made of stable fibrous deposits. Despite progress made towards identifying disease-related proteins, the underlying pat...

Codoping Enhanced Radioluminescence of Nanoscintillators for X-Ray-Activated Synergistic Cancer Therapy and Prognosis Using Metabolomics.

A multifunctional, nanoscintillator with diagnosis assisted synergistic radio- and photodynamic therapy holds the future glimpse to fight cancer. Further, integrating cancer therapy with untargeted metabolomic analysis would collectively offer clinical pertinence, through facilitating early diagnosis and prognosis. Here, we enriched scintillation of CeF3 nanoparticles (NPs) through codoping Tb3+ and Gd3+ (CeF3: Gd3+, Tb3+) for viable clinical approach in the treatment of deep-seated tumors. The codoped CeF3...

Two-Dimensional Materials in Biosensing and Healthcare: from Diagnostics to Optogenetics and Beyond.

Since the isolation of graphene in 2004, there has been an exponentially growing number of reports on layered two-dimensional (2D) materials for applications ranging from protective coatings to biochemical sensing. Due to the exceptional, and often tunable, electrical, optical, electrochemical, and physical properties of these materials, they can serve as the active sensing element or a supporting substrate for diverse healthcare applications. In this review, we provide a survey of the recent reports on the...

BaCuSiTe: A Noncentrosymmetric Semiconductor with CuTe Tetrahedra and Ethane-like SiTe Units.

BaCuSiTe was prepared from the elements in a solid-state reaction at 973 K, followed by slow cooling to room temperature. This telluride adopts a new, hitherto unknown structure type, crystallizing in the noncentrosymmetric space group with = 7.5824(1) Å, = 8.8440(1) Å, = 13.1289(2) Å, β = 122.022(1)°, and = 746.45(2) Å ( = 4). The structure consists of a complex network of two-dimensionally connected CuTe tetrahedra and ethane-like SiTe units with a Si-Si bond. This semiconducting material has a...

Strong correlation and charge localisation in Kohn-Sham theories with fractional orbital occupations.

We study static correlation and delocalisation errors and show that even methods with good energies can yield significant delocalization errors that affect the density, leading to large errors in predicting, e.g., dipole moments. We illustrate this point by comparing existing state-of-art approaches with an accurate exchange correlation functional based on a generalised valence-bond ansatz, in which orbitals and fractional occupations are treated as variational parameters via an optimized effective potentia...

Unique Structural Relaxations and Molecular Conformations of Porphyra-334 at the Excited State.

Quantum chemistry based simulations were used to examine the excited state of porphyra-334, one of the fundamental mycosporine-like amino acids present in a wide variety of aqueous organisms. Our calculations reveal three characteristic aspects of porphyra-334 related to either its ground or excited state. Specifically, (i) the ground state (S) structure consists of a planar geometry in which three units can be identified, the central cyclohexene ring, the glycine- and the threonine-branch, reflecting the ...

Disorder-to-Order Transition Mediated by Size Refocusing: A Route toward Monodisperse Intermetallic Nanoparticles.

Intermetallic nanoparticles are remarkable due to their often enhanced catalytic, magnetic, and optical properties, which arise from their ordered crystal structures and high structural stability. Typical syntheses of intermetallic nanoparticles include thermal annealing of the disordered counterpart in atmosphere (or vacuum) or colloidal syntheses, where the phase transformation is achieved in solution. Although both methods can produce intermetallic nanoparticles, there is difficulty in achieving nanopar...

Crossover Interference: Shedding Light on the Evolution of Recombination.

Through recombination, genes are freed to evolve more independently of one another, unleashing genetic variance hidden in the linkage disequilibrium that accumulates through selection combined with drift. Yet crossover numbers are evolutionarily constrained, with at least one and not many more than one crossover per bivalent in most taxa. Crossover interference, whereby a crossover reduces the probability of a neighboring crossover, contributes to this homogeneity. The mechanisms by which interference is ac...


Quick Search