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PubMed Journals Articles About "Andes 1537 Injection Tumor Solid" RSS

13:49 EDT 18th July 2019 | BioPortfolio

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Showing "Andes 1537 Injection Tumor Solid" PubMed Articles 1–25 of 12,000+

Effects of Body Mass Index and Biochemical Lipid Levels on Reproductive Outcomes during An Intracytoplasmic Sperm Injection: A Retrospective Study.

The aim of this study was to evaluate the impact of body mass index (BMI) and lipid profile on reproductive outcomes of women undergoing intracytoplasmic sperm injection (ICSI) cycles.


Association of IL-1 and TNF-α Levels in Endometrial Secretion and Success of Embryo Transfer in IVF/ICSI Cycles.

In this work, we have determined the levels of interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-α), which function as cytokines in endometrial receptivity, through the endometrial secretion within the eligible individuals and thus studied their relationships with the success or failure of pregnancy in fertilization/intra cytoplasmic sperm injection (IVF/ICSI) cycles.

Metastatic papillary thyroid cancer presenting with a recurrent necrotic cystic cervical lymph node

We report a case of metastatic papillary thyroid carcinoma presenting with a recurrent right-sided cervical lymph node necrotic cyst. A 55-year-old woman presented with a 3-month history of a right-sided upper neck mass following an upper respiratory tract infection. Past medical history includes a right-sided nephrectomy secondary to a benign renal tumor and hypertension. She was evaluated by Otolaryngology, and fine-needle aspiration was performed. The mass recurred 2 months following aspiration. Ultrasou...


Endowing Lithium Metal Surface with Self-healing Property via In-situ Gas-solid Reaction for High-performance Lithium Metal Batteries.

The property of solid electrolyte interphase (SEI) layer is of prime importance for the performance of lithium metal anodes. Replacing the spontaneously formed inhomogeneous and unstable SEI layer with a high-performance artificial SEI is an effective strategy. Herein, a self-healing SEI layer with high lithium ion conductivity and stable framework to address the issues of poor performance of lithium metal anode is achieved. C, Li2S and LiI are uniformly distributed on lithium surface via a "sauna" reaction...

Biophysical and biochemical characteristics as complementary indicators of melanoma progression.

The multi-step character of cancer progression makes it difficult to define a unique biomarker of the disease. Interdisciplinary approaches, combining various complimentary techniques, especially those operating at a nanoscale level, potentially accelerate characterization of cancer cells or tissue properties. Here, we study a relation between the surface and biomechanical properties of melanoma cells, measured by mass spectrometry (ToF SIMS) and atomic force microscopy (AFM). In total, seven cell lines hav...

Aptamer-Functionalized and Gold Nanoparticle Array-Decorated Magnetic Graphene Nanosheets Enable Multiplexed and Sensitive Electrochemical Detection of Rare Circulating Tumor Cells in Whole Blood.

The identification and monitoring of circulating tumor cells (CTCs) in human blood has a pivotal role for the convenient diagnosis of different cancers. However, it remains a major challenge to monitor these CTCs because of their extremely low abundances in human blood. Here, we describe the synthesis of a new aptamer-functionalized and gold nanoparticle (AuNP) array-decorated magnetic graphene nanosheet recognition probe to capture and isolate the rare CTCs from human whole blood. In addition, by employing...

A Tumor Targeting NIRF NanoGUMBOS with Cyclodextrin Enhanced Chemo/Photothermal Antitumor Activities.

The near-infrared fluorescent (NIRF) dye, IR780, is recognized as a promising theranostic agent and has been widely investigated for imaging, chemotherapeutic, and phototherapeutic applications. However, its poor photostability and non-selective toxicities towards both cancer and normal cells limit its biological applications. Herein, we introduce the use of GUMBOS (a group of uniform materials based on organic salts) developed through counter-anion exchange with IR780, and subsequent nanomaterials (nanoGUM...

A Multistimulus Responsive Porous Coordination Polymer: Temperature-Mediated Control of Solid-State 2+2 Cycloaddition.

Either of two different isomeric products can be selectively obtained by photochemical [2+2] cycloaddition of 1,4-bis[2-(4-pyridyl)ethenyl]-benzene within a porous coordination polymer (PCP). The cycloaddition product obtained depends on the temperature at which irradiation occurs. A rare temperature-induced phase transition alters the conformation of the photoactive ligand in the PCP, and thereby the positions at which cycloaddition occurs. We show that the multistimulus responsive nature of this particula...

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors.

Rocaglates are a family of natural products isolated from the genus Aglaia which possess a highly substituted cyclopenta[b]benzofuran skeleton and inhibit cap-dependent protein synthesis. Rocaglates are attractive compounds due to their potential for inhibiting tumor cell maintenance in vivo by specifically targeting eukaryotic initiation factor 4A (eIF4A) and interfering with recruitment of ribosomes to mRNA. In this paper, we describe an intercepted retro-Nazarov reaction utilizing intramolecular tosyl mi...

Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived .

Eight new sulfur-bridged pyranonaphthoquinone (PNQ) dimers, naquihexcins C-J (-), a new PNQ monomer, naquihexcin K (), and three known analogues (, , and ) were isolated from sp. KIB3133. The new structures were elucidated by interpretation of spectroscopic data. Dimer was synthesized via a cascade S2 reactions between two monomers and sodium sulfide, an approach motivated by the proposed biosynthetic pathway of dimeric pyranonaphthoquinones. Naquihexcin E () exhibited moderate HIV-1 inhibitory activity. ...

Correction to "Identification of Tumor Specific Peptide as EpCAM Ligand and Its Potential Diagnostic and Therapeutic Clinical Application".

Solid Pseudopapillary Neoplasms of the Pancreas: Clinicopathologic and Radiologic Features According to Size.

The purpose of this study was to retrospectively analyze and correlate clinicopathologic and radiologic features of resected solid pseudopapillary neoplasms of the pancreas according to their size. Clinicopathologic and radiologic features of 106 resected solid pseudopapillary neoplasms of the pancreas over a 20-year period were retrospectively analyzed. Tumors were divided into three groups according to their size (≤ 30 mm, 31-50 mm, and ≥ 51 mm). Clinicopathologic and radiologic features were compare...

CCAT1 promotes triple-negative breast cancer progression by suppressing miR-218/ZFX signaling.

Long non-coding RNAs (lncRNAs) regulate cancer development and progression. Here, we investigated the role of the lncRNA CCAT1 in triple-negative breast cancer (TNBC). CCAT1 expression was higher in TNBC cells than normal breast epithelial cells. Additionally, CCAT1 expression was higher in TNBC patient tumor tissue than adjacent normal breast tissue. Silencing CCAT1 inhibited TNBC cell proliferation, migration, and invasion , and tumor growth and progression . Bioinformatics analysis revealed that microRNA...

Sporadic perivascular epithelioid cell tumor of the wall of the jejunum A case report.

Perivascular epithelioid cell tumors are rare mesenchymal tumors composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. They are considered ubiquitous tumors and have been described in different organs, but gastro-intestinal PEComas are diseases of extreme rarity.

aza-BODIPY synthesis towards vis/NIR functional chromophores based on a Schiff base forming reaction protocol using lactams and heteroaromatic amines.

aza-BODIPY is a class of heteroatom-containing BODIPY analogues targeting near infrared (NIR) chromophores and fluorophores. As a synthetic strategy towards aza-BODIPY structures, we have, recently, developed a Schiff base forming reaction using readily available lactams and heteroaromatic amines. Absorption and fluorescence of a series of compounds cover the whole range of the ultraviolet (UV)/visible (vis)/NIR regions. In addition, some compounds exhibit solid state emission, aggregation-induced emission ...

Inkjet-printed co-continuous mesoporous oxides for high-current power transistors.

Limited printing resolution has always been a major hindrance for printed electronics; irrespective of the high mobility demonstrated by solution-processed semiconductors, long-channel printed field-effect transistors (FETs) have demonstrated low On-state conductance and switching speeds. Although various concepts have been proposed to obtain narrow-channel printed FETs, the actual demonstration of high On-currents/channel conductance has been rare. In this context, herein, we report a general recipe to pri...

Luminescence properties of Yb-doped SrTiO: the significance of the oxygen-titanium charge transfer state on photon downshifting.

Ceramic powders of Sr1-1.5xYbxTiO3 (x = 0.0, 0.0125, 0.025, 0.05 and 0.075) solid solutions were synthesized by the polymeric complex method. The crystal structure, microstructure and optical properties of the powders annealed at 800 °C for 1 h were investigated by X-ray diffraction, scanning electron microscopy, and diffuse reflectance and photoluminescence spectroscopy, respectively. All the solid solutions exhibit a cubic perovskite-like structure. The reflectance spectra show a broadband below 400 nm a...

Nano-WO -SO H as a New Photocatalyst Insight Through Covalently Grafted Brønsted Acid: Highly Efficient Selective Oxidation of Benzyl Alcohols to Aldehydes.

Modification of nano-WO with -SO H groups as a covalently grafted solid acid reduced its band gap energy from 2.8 to 2.4 eV and made it an ideal nominee for photocatalytic reaction under visible light irradiation. This nano-photocatalyst has been successfully used for the selective oxidation of different benzyl alcohols to corresponding aldehydes under blue LED irradiation. The reaction became approximately two times faster with excellent yields. It has shown that the nitrobenzene as an available industrial...

Spatial and temporal patterns and socioeconomic impact of landslides in the tropical and mountainous Colombian Andes.

Landslides are a natural hazard that represents a major threat to human life and infrastructure. Although landslides are a very common phenomenon in Colombia, there is a lack of studies presenting a national and comprehensive spatial, temporal and socioeconomic analysis of these events. This study presents a detailed analysis of the spatial and temporal trends of landslide occurrence in Colombia from 1900 to 2018. Two national landslide databases were consulted and complemented with regional and local lands...

Histopathological changes in tumor budding between biopsy and resected specimens from patients treated with preoperative S-1 chemotherapy for oral cancer.

S-1 is an oral anticancer agent containing tegafur, a prodrug of 5-fluorouracil (5-FU). Preoperative S-1 chemotherapy is performed to prevent tumor proliferation before surgery in oral squamous cell carcinoma (OSCC). The aim of this study was to evaluate the effects of preoperative S-1 chemotherapy on tumor budding.

Acquired Hypersensitivity to Dupilumab: First Case Report.

Dupilumab is the first targeted biologic therapy for the systemic treatment of atopic dermatitis. It is a fully human monoclonal antibody (mAb) directed against the shared alpha subunit of the interleukin (IL)-4-receptor component of the type I and type II receptors, thereby inhibiting IL-4 and IL-13 signaling. Injection site reactions are among the most common adverse effects reported. We herein report the first case of acquired hypersensitivity to Dupixent confirmed by cutaneous allergy testing necessi...

Merkel cell carcinoma: a prompt diagnosis to increase survival.

Merkel cell carcinoma (MCC) is a rare, malignant tumor related to advanced age and immunusoppression . Its incidence has been increased over decades but management is still controversial . Looking for MCC cases over the last ten years, nine cases were retrieved (6 females and 3 males, median age 71 years, for clinical data see Table 1). This article is protected by copyright. All rights reserved.

A multistate model for early decision-making in oncology.

The development of oncology drugs progresses through multiple phases, where after each phase, a decision is made about whether to move a molecule forward. Early phase efficacy decisions are often made on the basis of single-arm studies based on a set of rules to define whether the tumor improves ("responds"), remains stable, or progresses (response evaluation criteria in solid tumors [RECIST]). These decision rules are implicitly assuming some form of surrogacy between tumor response and long-term endpoints...

MicroRNA-140 inhibit prostate cancer cell invasion and migration by targeting YES proto-oncogene 1.

Prostate cancer (PCa), which is an aggressive malignancy of the male genitourinary system. In the present study, the effects of microRNA-140 (miR-140) on PCa were determined. We transfected miR-140 mimics or negative control into PCa cells, and we used MTT, wound healing, and Transwell assays for determining the capacities of miR-140 in cell proliferation, migration, and invasion, respectively. We also confirmed the relationship between miR-140 and YES proto-oncogene 1 (YES1) using Luciferase reporter assay...

Gold(I) Complexes Stabilized by Nine- and Ten-Membered N-Heterocyclic Carbene Ligands.

Nine- and ten-membered N-heterocyclic carbene (NHC) ligands have been developed and for the first time their gold(I) complexes are synthesized. The protonated NHC pro-ligands 2a-h were prepared by the reaction of readily available N,N'-diarylformamidines with bis-electrophilic building blocks, followed by anion exchange. In-situ deprotonation of the tetrafluoroborates 2a-h with tBuOK in the presence of AuCl(SMe2) provided fast access to NHC-gold(I) complexes 3-10. These new NHC-gold(I) complexes show very g...


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