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PubMed Journals Articles About "Brain Structure Cognitive Ability Healthy Aging Review Longitudinal" RSS

13:54 EDT 18th July 2019 | BioPortfolio

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Showing "Brain structure cognitive ability healthy aging review longitudinal" PubMed Articles 1–25 of 48,000+

The Genetics of Non-Syndromic Primary Ovarian Insufficiency: A Systematic Review.

Several causes for primary ovarian insufficiency (POI) have been described, including iatrogenic and environmental factor, viral infections, chronic disease as well as genetic alterations. The aim of this review was to collect all the genetic mutations associated with non-syndromic POI. All studies, including gene screening, genome-wide study and assessing genetic mutations associated with POI, were included and analyzed in this systematic review. Syndromic POI and chromosomal abnormalities were not evaluat...


Rubella Immunity in Pregnant Iranian Women: A Systematic Review and Meta-Analysis.

Rubella infection within the first trimester of pregnancy may lead to adverse pregnancy outcomes. The present study was conducted to evaluate the immunity against rubella among the pregnant Iranian women. The steps of meta-analyses were conducted based on the MOOSE protocol and results were reported according to the PRISMA guideline. To review the associated English and Persian literature, a comprehensive search was conducted among the international databases such as Scopus, PubMed/Medline, Science Direct, ...

Focused Electron Beam Induced Deposition (FEBID) and Post-Growth Purification Using the Heteroleptic Ru Complex (η-CH)Ru(CO)Br.

Focused electron beam induced deposition using the heteroleptic complex (η-CH)Ru(CO)Br as a precursor resulted in deposition of material with Ru content of 23 at%. TEM images indicated a nanogranular structure of pure Ru nanocrystals, embedded into a matrix containing carbon, oxygen and bromine. The deposits were purified by annealing in a reactive 98% N / 2% H atmosphere at 300 ºC, resulting in reduction of contaminants and an increase of Ru content to 83 at%. Although a significant 79% volume loss was f...


Synthesis of Porous Si/C Composite Nanosheets from Vermiculite with a Hierarchical Structure as a High-Performance Anode for Lithium-Ion Battery.

Silicon nanosheets are fascinating anode materials for lithium-ion batteries because of their high specific capacities, structural stability, and fast kinetics in alloying/dealloying with Li. The nanosheets can be synthesized through chemical vapor deposition (CVD), topochemical reaction, and templating method. After coating with a carbon nanolayer, they exhibit enhanced electrochemical performance. However, it is challenging to synthesize ultrathin carbon-coated silicon nanosheets. In this work, porous sil...

Precious Metal-Free Nickel Nitride Catalyst for the Oxygen Reduction Reaction.

With promising activity and stability for the oxygen reduction reaction (ORR), transition metal nitrides are an interesting class of non-platinum group catalysts for polymer electrolyte membrane fuel cells. Here, we report an active thin-film nickel nitride catalyst synthesized through a reactive sputtering method. In rotating disk electrode testing in a 0.1 M HClO electrolyte, the crystalline nickel nitride film achieved high activity and selectivity to four-electron ORR. It also exhibited good stability d...

Organic and Organometallic Chemistry at the Single-Molecule, -Particle, and -Molecular-Catalyst-Turnover Level by Fluorescence Microscopy.

Mechanistic studies have historically played a key role in the discovery and optimization of reactions in organic and organometallic chemistry. However, even apparently simple organic and organometallic transformations may have surprisingly complicated multistep mechanisms, increasing the difficulty of extracting this mechanistic information. The resulting reaction intermediates often constitute a small fraction of the total reaction mixture, for example, creating a long-term analytical challenge of detecti...

Effect of Fluorination on the Structure and Anti- Activity of Oxorhenium(V) Complexes with ,,-Tridentate Thiosemicarbazones and Benzoylthioureas. Synthesis and Structures of Technetium(V) Analogues.

A series of 16 "3 + 2" mixed-ligand complexes of the general composition [ReO(L1)(L2)] (HL1a-HL1d = tridentate thiosemicarbazones having a phenyl group with 4-H, 4-F, 3,5-di-F, and 4-CF substituents; HL2a-HL2d = bidentate ,-diethyl-'-benzoylthioureas with 4-H, 4-F, 3,5-di-F, and 4-CF substituents at the benzoyl groups) have been synthesized and characterized by spectroscopic methods and X-ray diffraction. Irrespective of the individual fluorine substitution, the complexes are stable and possess the same gen...

High-Resolution ENDOR Spectroscopy Combined with Quantum Chemical Calculations Reveals the Structure of Nitrogenase Janus Intermediate E(4H).

We have shown that the key state in N reduction to two NH molecules by the enzyme nitrogenase is E(4H), the "Janus" intermediate, which has accumulated four [e/H] and is poised to undergo reductive elimination of H coupled to N binding and activation. Initial H and Mo ENDOR studies of freeze-trapped E(4H) revealed that the catalytic multimetallic cluster (FeMo-co) binds two Fe-bridging hydrides, [Fe-H-Fe]. However, the analysis failed to provide a satisfactory picture of the relative spatial relationships o...

Intercepted Retro-Nazarov Reaction: Syntheses of Amidino-Rocaglate Derivatives and Their Biological Evaluation as eIF4A Inhibitors.

Rocaglates are a family of natural products isolated from the genus Aglaia which possess a highly substituted cyclopenta[b]benzofuran skeleton and inhibit cap-dependent protein synthesis. Rocaglates are attractive compounds due to their potential for inhibiting tumor cell maintenance in vivo by specifically targeting eukaryotic initiation factor 4A (eIF4A) and interfering with recruitment of ribosomes to mRNA. In this paper, we describe an intercepted retro-Nazarov reaction utilizing intramolecular tosyl mi...

Influence of Thiazole-modified Carbon Nitride Nanosheets with Feasible Electronic Properties on Inverted Perovskite Solar Cells.

Effective, solution processable designs of interfacial electron transporting layers (ETLs) or hole-blocking layers are promising tools in modern electronic devices, e.g. to improve performance, cost and stability of perovskite-based solar cells. Herein, we introduce a facile synthetic route of thiazole-modified carbon nitride with 1.5 nm thick nanosheets which can be processed to a homogeneous, metal-free ETL for inverted perovskite solar cells. We show that thiazole-modified carbon nitride enables electron...

Gradients of gluten proteins and free amino acids along the longitudinal axis of the developing caryopsis of bread wheat.

Gradients in the contents and compositions of gluten proteins and free amino acids and the expression levels of gluten protein genes in developing wheat caryopses were determined by dividing the caryopsis into three longitudinal sections: proximal (En1), middle (En2) and distal (En3) to embryo. The total gluten protein content was lower in in En1 than in En2 and En3, with decreasing proportions of HMW-GS, LMW GS and α/β, γ-gliadins and increasing proportions of ω-gliadins. These differences were associa...

Scavenging of Acrolein by a Food-Grade Antioxidant Propyl Gallate in model reaction system and in Cakes.

Reactive carbonyl species (RCS), such as acrolein (ACR), glyoxal (GO), and methylglyoxal (MGO) have received extensive attention recently due to their high activity and toxicity in vitro and in vivo. In the present study, propyl gallate (PG), a common food antioxidant, was found to effectively trap more ACR than butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) through the formation of mono-ACR adducts (PG-ACR) and di-ACR adducts (PG-2ACR). The two adducts were successfully purified, and the...

Bioinspired Adhesion Polymers - Wear Resistance of Adsorption Layers.

Mussel adhesive polymers owe their ability to strongly bind to a large variety of surfaces under water due to their high content of 3,4-dihydroxy-l-phenylalanine (DOPA) groups and high positive charge. In this work we use a set of statistical copolymers that contain medium length poly(ethylene oxide) side chains that are anchored to the surface in three different ways: by means of i) electrostatic forces, ii) catechol groups (as in DOPA), and iii) the combination of electrostatic forces and catechol groups....

Sphingolipidomics investigation of the temporal dynamics after ischemic brain injury.

Sphingolipids (SPL) have been proposed as a potential therapeutic target for strokes, but no reports have ever profiled the changes of the entire range of SPLs after stroke. This study applied sphingolipidomic methods to investigate the temporal and individual changes in the sphingolipidome including the effect of atorvastatin after ischemic brain injury. We conducted sphingolipidomic profiling of mouse brain tissue by liquid chromatography-electrospray ionization tandem mass spectrometry at 3 hour (hr) and...

Gold Nanotetrapods with Unique Topological Structure and Ultra-Narrow Plasmonic Band as Multifunctional Therapeutic Agents.

Owing to their excellent surface plasmonic properties, Au nanobranches have drawn increasing attention in various bio-applications, such as contrast agents for photoacoustic imaging, nanomedicines for photothermal therapy, and carriers for drug delivery. The monodispersity and plasmonic band width of Au nanobranches are of great importance for the efficacy of those bio-applications. However, it is still a challenge to accurately synthesize size- and shape-controlled Au nanobranches. Here we report a facile ...

Dimerization of the sodium/iodide symporter (NIS).

Background The ability of thyroid follicular epithelial cells to accumulate iodide via the sodium/iodide symporter (NIS) is exploited to successfully treat most thyroid cancers, although a subset of patients lose functional NIS activity and become unresponsive to radioiodide therapy, with poor clinical outcome. Our knowledge of NIS regulation remains limited, however. Whilst numerous membrane proteins are functionally regulated via dimerization, there is little definitive evidence of NIS dimerization, and w...

An Investigation Into the Factor Structure of the Attitudes to Suicide Prevention Scale.

The aim of this study was to investigate the factor structure of the Attitudes to Suicide Prevention Scale (ASPS). The ASPS was distributed to all staff in a UK National Health Service Trust ( = 957). We conducted an exploratory factor analysis followed by a confirmatory factor analysis by splitting the data 60/40 into training and testing subsets. A multiple regression analysis was carried out to investigate whether the overall scale score varied as a function of professional role, age, and gender and whe...

Preliminary Assessment of Visible, Near-Infrared, and Short-Wavelength-Infrared Spectroscopy with a Portable Instrument for the Detection of Biofilms on Surfaces.

Bacterial biofilms constitute a major source of sanitary problems and economic losses in the food industry. Indeed, biofilm removal may require intense mechanical cleaning procedures or very high concentrations of disinfectants or both, which can be damaging to the environment and human health. This study assessed the efficacy of a technique based on spectroscopy in the visible, near-infrared, and short-wavelength infrared range for the quick detection of biofilms formed on polystyrene by the pathogenic bac...

Safety Considerations of 7-T MRI in Clinical Practice.

Although 7-T MRI has recently received approval for use in clinical patient care, there are distinct safety issues associated with this relatively high magnetic field. Forces on metallic implants and radiofrequency power deposition and heating are safety considerations at 7 T. Patient bioeffects such as vertigo, dizziness, false feelings of motion, nausea, nystagmus, magnetophosphenes, and electrogustatory effects are more common and potentially more pronounced at 7 T than at lower field strengths. Herein t...

The Safety of Maternal and Fetal MRI at 3T.

The purpose of this study was to evaluate the effects of clinical 3-T MRI during pregnancy on fetal growth and neonatal hearing in neonates at low risk of congenital hearing impairment or of brain or chromosomal abnormalities. This single-center retrospective case-control study included consecutively born healthy neonates exposed in utero to 3-T MR during MRI for maternal or fetal indications and born between January 2008 and March 2015. Each exposed neonate was randomly matched 1:2 by birth date to health...

Frontal Occipital and Frontal Temporal Horn Ratios: Comparison and Validation of Head Ultrasound-Derived Indexes With MRI and Ventricular Volumes in Infantile Ventriculomegaly.

The purpose of our study was to assess whether linear ventricular dimensions-specifically, the frontal occipital horn ratio (FOHR) and frontal temporal horn ratio (FTHR) obtained from ultrasound (US)-are reliable measures of ventriculomegaly in infants. Our hypothesis was that these US measures would show good correlation with linear ventricular indexes and ventricular volumes obtained from MRI. We retrospectively identified 90 infants (age ≤ 6 months corrected gestational age) with ventriculomegaly from...

Evidence for Differential Predictive Performance of the Prime Screen Between Black and White Help-Seeking Youths.

Self-report screening instruments for emerging psychosis have the potential to improve early detection efforts by increasing the number of true positives among persons deemed to be at "clinical high risk" of the disorder, but their practical utility depends on their validity across race. This study sought to examine whether a commonly used self-report screening tool for psychosis risk performed equally among black and white youths in its ability to predict clinical high-risk status.

Rift Valley fever: biology and epidemiology.

Rift Valley fever (RVF) is a mosquito-borne viral zoonosis that was first discovered in Kenya in 1930 and is now endemic throughout multiple African countries and the Arabian Peninsula. RVF virus primarily infects domestic livestock (sheep, goats, cattle) causing high rates of neonatal mortality and abortion, with human infection resulting in a wide variety of clinical outcomes, ranging from self-limiting febrile illness to life-threatening haemorrhagic diatheses, and miscarriage in pregnant women. Since it...

Intact Mycobacterium leprae Isolated from Placenta of a Pregnant Woman, China.

Whether Mycobacterium leprae transmits from placenta to fetus remains unknown. We describe the case of a pregnant woman with untreated histoid leproma. Although her newborn was healthy, laboratory examination revealed intact M. leprae present in the placenta, suggesting that the placental barrier might prevent vertical dissemination of M. leprae.

No Evidence for Role of Cutavirus in Malignant Melanoma.

Cutavirus was previously found in cutaneous melanoma. We detected cutavirus DNA in only 2/185 melanoma biopsies and in 0/52 melanoma metastases from patients in Germany. Viral DNA was localized in the upper epidermal layers. Swab specimens from healthy skin were cutavirus positive for 3.8% (9/237) of immunocompetent and 17.1% (35/205) of HIV-positive men.


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