Topics

PubMed Journals Articles About "Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under" RSS

05:34 EDT 24th August 2019 | BioPortfolio

Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under articles that have been published worldwide.

More Information about "Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under" on BioPortfolio

We have published hundreds of Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under news stories on BioPortfolio along with dozens of Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under Clinical Trials and PubMed Articles about Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under Companies in our database. You can also find out about relevant Declined Cadmium Accumulation Antiporter NHX1 Transgenic Duckweed Under Drugs and Medications on this site too.

Showing "Declined cadmium accumulation antiporter NHX1 transgenic duckweed under" PubMed Articles 1–25 of 4,900+

Identification and functional expression of two subtypes of glycerol-3-phosphate acyltransferase differently regulating triacylglyceride synthesis during ovary development in Chinese mitten crab, Eriocheir sinensis.

Triacylglycerides (TAG) are a pivotal nutrient for crustacean reproduction, rapidly accumulating in gonads and hepatopancreas during the ovary development. Glycerol-3-phosphate acyltransferase (GPAT) is the enzyme catalyzing the first step in TAG synthesis. In the present study, two EsGPATs subtypes (EsGPAT1 and EsGPAT2) were identified and characterized. The transcript of EsGPAT1 was highly expressed in thoracic ganglia, hepatopancreas and ovary, while EsGPAT2 was mainly detected in nervous tissues and int...


The phosphatase activity of soluble epoxide hydrolase regulates ATP-binding cassette transporter-A1-dependent cholesterol efflux.

The contribution of soluble epoxide hydrolase (sEH) to atherosclerosis has been well defined. However, less is understood about the role of sEH and its underlying mechanism in the cholesterol metabolism of macrophages. The expression of sEH protein was increased in atherosclerotic aortas of apolipoprotein E-deficient mice, primarily in macrophage foam cells. Oxidized low-density lipoprotein (oxLDL) increased sEH expression in macrophages. Genetic deletion of sEH (sEH ) in macrophages markedly exacerbated ox...

Comparative Transcriptomic Analysis Reveals Regulatory Mechanisms of Theanine Synthesis in Tea (Camellia sinensis) and Oil Tea (Camellia. oleifera) Plants.

Tea provides a rich taste and has healthy properties due to its variety of bioactive compounds, such as theanine, catechins and caffeine. Theanine is the most abundant free amino acid (40%70%) in tea leaves. Key genes related to theanine biosynthesis have been studied, but relatively little is known about the regulatory mechanisms of theanine accumulation in tea leaves. Herein, we analyzed theanine content in tea (Camellia sinensis) and oil tea (C. oleifera), and found it to be higher in roots than other...


"We know this will be hard at the beginning, but better in the long term": understanding PrEP uptake in the general population in Eswatini.

Information regarding HIV pre-exposure prophylaxis (PrEP) for the general population is largely lacking, because the majority of PrEP demonstration projects have focused on key populations. This qualitative study examines barriers and facilitators to PrEP uptake and adherence among the general population in Eswatini, where PrEP is offered through public-sector primary-care clinics. We analysed 106 semi-structured in-depth interviews with healthcare workers ( = 26), stakeholders ( = 30), and clients ...

Functional sustainability of nutrient accumulation by periphytic biofilm under temperature fluctuations.

Temperature can fluctuate widely between different seasons, and this may greatly impact many biological process. However, little is known about its influence on the functioning of benthic microbial communities. Here we investigated the nutrient accumulation capability of periphytic biofilm under temperature fluctuations (17-35 °C). Periphytic biofilm maintained the same nutrient accumulation capacity after experiencing the "warming-hot-cooling" temperature fluctuation under both lab and outdoor conditions ...

Capsaicin, an inhibitor of Ochratoxin A production by section strains in grapes ( L.).

Food decay by spoilage fungi leads to significant economic losses and hazards to consumers' health due to the potential of mycotoxin occurrence. Ochratoxin A (OTA) is a mycotoxin known as nephrotoxic and carcinogenic to humans. Natural capsaicin was evaluated for its effectiveness against the growth of five section strains and accumulation of OTA in inoculated black grapes. Results showed that capsaicin was effective in inhibiting fungal growth and OTA production by new four section strains (ATHUM 6997,...

Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule.

Overexpression of myo-inositol oxygenase (MIOX), a proximal tubular enzyme, exacerbates cellular redox injury in acute kidney injury (AKI). Ferroptosis, a newly coined term associated with lipid hydroperoxidation, plays a critical role in the pathogenesis of AKI. Whether or not MIOX exacerbates tubular damage by accelerating ferroptosis in Cisplatin-induced AKI remains elusive. Cisplatin-treated HK-2 cells exhibited notable cell death, which was reduced by ferroptosis inhibitors. Also, alterations in variou...

Progress Toward Poliomyelitis Eradication - Afghanistan, January 2018-May 2019.

Since October 2016, Afghanistan and Pakistan have been the only countries with reported cases of wild poliovirus type 1 (WPV1) (1). In Afghanistan, although the number of cases had declined during 2013-2016, the polio eradication program experienced challenges during 2017-2019. This report describes polio eradication activities and progress in Afghanistan during January 2018-May 2019 and updates previous reports (2,3). During May-December 2018, insurgent groups (antigovernment elements) banned house-to-hous...

The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility.

The ubiquitin proteasome system regulates meiotic recombination in yeast through its association with the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. In mammals, the proteasome activator subunit PA200 targets acetylated histones for degradation during somatic DNA double strand break repair and during histone replacement during spermiogenesis. We investigated the role of the testis-specific proteasomal subunit α4s (PSMA8) duri...

Chlorella vulgaris genome assembly and annotation reveals the molecular basis for metabolic acclimation to high light conditions.

Chlorella vulgaris is a fast-growing fresh-water microalga cultivated at the industrial scale for applications ranging from food to biofuel production. To advance our understanding of its biology and to establish genetics tools for biotechnological manipulation, we sequenced the nuclear and organelle genomes of Chlorella vulgaris 211/11P by combining next generation sequencing and optical mapping of isolated DNA molecules. This hybrid approach allowed to assemble the nuclear genome in 14 pseudo-molecules wi...

The overexpression of rice ACYL-COA-BINDING PROTEIN2 increases grain size and bran oil content in transgenic rice.

As Oryza sativa (rice) seeds represent food for over three billion people worldwide, the identification of genes that enhance grain size and composition is much desired. Past reports have indicated that Arabidopsis thaliana acyl-CoA-binding proteins (ACBPs) are important in seed development but did not affect seed size. Herein, rice OsACBP2 was demonstrated not only to play a role in seed development and germination, but also to influence grain size. OsACBP2 mRNA accumulated in embryos and endosperm of germ...

Cinnamate:CoA-ligase is involved in benzoate-derived biphenyl phytoalexin biosynthesis in Malus × domestica 'Golden Delicious' cell cultures.

Apple (Malus sp.) and other genera belonging to the sub-tribe Malinae of the Rosaceous family produce unique benzoic acid-derived biphenyl phytoalexins. Cell cultures of Malus domestica cv. 'Golden Delicious' accumulate two biphenyl phytoalexins, aucuparin and noraucuparin, in response to the addition of Venturia inaequalis elicitor (VIE). In this study, we isolated and expressed a cinnamate-CoA ligase-encoding sequence in VIE-treated cell cultures of cv. 'Golden Delicious' (M. domestica CNL; MdCNL). MdCNL ...

Behavioural impairments in mice of a novel FUS transgenic line recapitulate features of frontotemporal lobar degeneration.

Multiple clinical and experimental evidence suggest that ALS and FTLD are members of a disease continuum. Pathological FUS inclusions have been observed in subsets of patients with these diseases but their anatomical distribution is different for two diseases. These structures are present in motor neurons in ALS cases but in cortical neurons in FTLD cases. Expression of a C-terminally truncated form of human FUS causes an early onset and progressive motor neuron pathology in transgenic mice but only when th...

Sex solves Haldane's dilemma.

The cumulative reproductive cost of multi-locus selection has been seen as a potentially limiting factor on the rate of adaptive evolution. In this paper, we show that Haldane's arguments for the accumulation of reproductive costs over multiple loci are valid only for a clonally reproducing population of asexual genotypes. We show that a sexually reproducing population avoids this accumulation of costs. Thus, sex removes a perceived reproductive constraint on the rate of adaptive evolution. The significance...

Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal.

Accumulating evidence from preclinical and clinical studies has implicated a role for the cytokine IL-6 in a variety of CNS diseases including anxiety-like and depressive-like behaviors, as well as alcohol use disorders. Here we use homozygous and heterozygous transgenic mice expressing elevated levels of IL-6 in the CNS due to increased astrocyte expression and non-transgenic littermates to examine a role for astrocyte-produced IL-6 in emotionality (response to novelty, anxiety-like, and depressive-like be...

The roles of TG-interacting factor in cadmium exposure-promoted invasion and migration of lung cancer cells.

Cadmium (Cd) is an established human carcinogen. Previous documents have demonstrated the association of Cd exposure with lung cancer progression. However, the underlying mechanisms of Cd-promoted invasion and migration of lung cancer cells have not yet been fully understood. The objective of this study was to explore the functional roles of TG-interacting factor (TGIF) in Cd exposure-promoted invasion and migration of lung cancer cells. Lung cancer cells were exposed to Cd for eight weeks. Invasion assay a...

MicroCT analyses of mouse femoral neck architecture.

Hip fractures at the femoral neck are a major cause of morbidity and mortality, but aside from biomechanical strength testing, little is known about femoral neck architecture in mice. Procedures were optimized to analyze high-resolution (6 μm voxel size) microCT scans of the mouse femoral neck to provide bone mass and architectural information. Similar to histomorphometric observations in rats, the boundary between cortical and trabecular bone is difficult to identify in the mouse femoral mid-neck and th...

A porphyrin-based optical sensor membrane prepared by electrostatic self-assembled technique for online detection of cadmium(II).

An optical sensor membrane was prepared by electrostatic self-assembled technique for online detection of cadmium ion (II) (Cd(II)). The optical indicator 5,10,15,20-tetrakis(4-N-methylpyridyl) porphyrin p-toluenesulfonate (TMPyP) was adsorbed on a hydrolyzed polyacrylonitrile (PAN) membrane by electrostatic attraction and further immobilized through layer-by-layer deposition of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) on the membrane surface. The electrostatic self-ass...

Associations among amyloid status, age, and longitudinal regional brain atrophy in cognitively unimpaired older adults.

The goal of this study was to compare regional brain atrophy patterns in cognitively unimpaired (CU) older adults with and without brain accumulation of amyloid-β (Aβ) to elucidate contributions of Aβ, age, and other variables to atrophy rates. In 80 CU participants from the Alzheimer's Disease Neuroimaging Initiative, we determined effects of Aβ and age on longitudinal, regional atrophy rates, while accounting for confounding variables including sex, APOE ε4 genotype, white matter lesions, and cerebro...

Zinc effects on cadmium toxicity in two wheat varieties (Triticum aestivum L.) differing in grain cadmium accumulation.

Presence of cadmium (Cd) in food poses serious risks to human health. Understanding the effects of zinc (Zn) on Cd absorption by crops could help provide a theoretical basis for the treatment with Zn on contaminated soils. In this study, two wheat varieties, differing in grain-Cd accumulation ability (L979, a Cd low-accumulation variety, and H27, a high-accumulation variety) were selected to investigate the effect of Zn addition on Cd toxicity. Cd was applied to nutrient solutions at 0 and 10 μM, and add...

Toxicological, gene expression and histopathological evaluations of environmentally realistic concentrations of polybrominated diphenyl ethers PBDE- 47, PBDE-99 and PBDE-209 on zebrafish embryos.

Polybrominated diphenyl ethers (PBDEs) are brominated flame retardants. Biomonitoring studies have shown widespread presence of PBDEs in humans and their accumulation in food chain cause concern to human health, especially for foetus and infant development. The early-life stages are generally considered more sensitive to exposure to toxic compounds than juvenile or adults. For this reason the aim of this study was to evaluate the effects of the three most environmentally relevant BDE (BDE- 47, 99 and 209) o...

SDF-1/CXCR4 axis facilitates myeloid-derived suppressor cells accumulation in osteosarcoma microenvironment and blunts the response to anti-PD-1 therapy.

Immune checkpoint inhibitors, such as anti-PD-1/PD-L1, are a novel class of inhibitors that function as a tumor suppressing factor via modulation of immune cell-tumor cell interaction. To date, PD-1/PD-L1 inhibitors have been approved for the treatment of specific types of tumors and obtained good clinical efficacy. However, patients with osteosarcoma showed poor response to anti-PD-1/PD-L1 therapy, the mechanism of which is not well understood. In this study, we found that osteosarcoma tissues were heavily...

Comparative physiological and metabolomic analyses of the hyper-accumulation of astaxanthin and lipids in Haematococcus pluvialis upon treatment with butylated hydroxyanisole.

The major goal of this study was to explore the functions of butylated hydroxyanisole (BHA) combined with abiotic stress on the cultivation of the microalga Haematococcus pluvialis for astaxanthin and lipid production. Here, the effect of BHA on astaxanthin and lipid accumulation and physiological and metabolomic profiles was investigated. These results suggested that astaxanthin content was increased by 2.17-fold compared to the control. The lipid content was enhanced by 1.22-fold. BHA treatment simultaneo...

Increased uranium concentrations in ground and surface waters of the Swiss Plateau: A result of uranium accumulation and leaching in the Molasse basin and (ancient) wetlands?

Increased uranium (U) concentrations are found in certain ground and surface waters of the Swiss Plateau. Analysis of more than 100 public fountains revealed that increased U concentrations frequently occur close to the interface between the Lower Freshwater Molasse and the Upper Marine Molasse, cropping out in the western part of the Swiss Molasse Basin. Out of these locations, Mont Vully, situated ca. 20 km west of Berne, was studied in detail. As this hill consists of the two aforementioned stratigraph...

Genome-wide analysis and functional characterization of Acyl-CoA:diacylglycerol acyltransferase from soybean identify GmDGAT1A and 1B roles in oil synthesis in Arabidopsis seeds.

Acyl-CoA:diacylglycerol acyltransferase (DGAT) is a key enzyme in the Kennedy pathway of triacylglycerol (TAG) synthesis. It catalyzes the acyl-CoA-dependent acylation of sn-1, 2-diacylglycerol to form TAG. DGATs in soybean (Glycine max) have been reported, but their functions are largely unclear. Here we cloned three members of DGAT1 and four members of DGAT2 family from soybean, named GmDGAT1A to GmDGAT1C, and GmDGAT2A to GmDGAT2D, respectively. GmDGAT1A and GmDGAT1C were expressed at a high level in imma...


Quick Search