PubMed Journals Articles About "Mental Stress Test Obstructive Coronary Atherosclerosis" RSS

17:00 EDT 16th July 2019 | BioPortfolio

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Showing "Mental Stress Test Obstructive Coronary Atherosclerosis" PubMed Articles 1–25 of 20,000+

Impact of Huntington's Disease on Mental Rotation Performance in Motor Pre-Symptomatic Individuals.

Huntington's disease (HD) is a genetic disorder known for affecting motor control. Despite evidence for the impact of HD on visual cortico-striatal loops, evidence for impaired visual perceptual in early symptomatic HD patients is limited; much less is known about what happens during the HD prodrome.

The Qualification of an Enrichment Biomarker for Clinical Trials Targeting Early Stages of Parkinson's Disease.

As therapeutic trials target early stages of Parkinson's disease (PD), appropriate patient selection based purely on clinical criteria poses significant challenges. Members of the Critical Path for Parkinson's Consortium formally submitted documentation to the European Medicines Agency (EMA) supporting the use of Dopamine Transporter (DAT) neuroimaging in early PD. Regulatory documents included a comprehensive literature review, a proposed analysis plan of both observational and clinical trial data, and an ...

Effect of paired-pulse stimulus parameters on the two phases of short interval intracortical inhibition in the quadriceps muscle group.

Short interval intracortical inhibition (SICI) is commonly used to assess inhibition in the motor cortex and is known to be affected by the paired-pulse stimulus parameters (i.e., interstimulus interval [ISI], conditioning stimulus intensity [CSI] and test stimulus intensity [TSI]) used during testing. While the effects of stimulus parameters are well-studied in the upper-extremity, evidence in the lower-extremity is lacking.

Elevated indoleamine-2,3-dioxygenase enzyme activity in a novel mouse model of HIV-associated atherosclerosis.

HIV atherosclerosis and cardiovascular disease (CVD) represent a significant human health burden in the era of combination antiretroviral therapy (cART). The pathogenesis of HIV atherosclerosis is still poorly understood, due, in part, to the lack of a suitable small animal model. Indoleamine-2,3-dioxygenase (IDO) enzyme activity is the first and rate-limiting step in tryptophan catabolism and is measured by the kynurenine to tryptophan ratio (KTR). The serum KTR is a biomarker of inflammation and has recen...

Osteochondroma of the Pubic Symphysis Involved With Aberrantly Placed Minisling: A Case Report.

Osteochondromas are benign bone tumors that rarely involve the pubic symphysis. This case report describes a 41-year-old woman with a pubic symphyseal osteochondroma associated with an aberrantly placed single incision sling. After an outside surgeon placed a single incision midurethral sling for stress urinary incontinence, she developed pelvic pain, dyspareunia and vaginal mesh sling exposure. Imaging demonstrated a 2.6 centimeter calcified mass posterior to the pubic symphysis. The patient underwent exci...

Added Value of Myocardial Blood Flow Quantification and Calcium Scoring During CZT SPECT Myocardial Perfusion Imaging for Coronary Artery Disease Screening.

Dedicated cadmium-zinc-telluride cardiac cameras have been shown to provide accurate measurements of absolute myocardial blood flow and flow reserve when PET is not available. We report the case of a 66-year-old woman who underwent 1-day stress/rest myocardial perfusion imaging (MPI) for coronary artery disease (CAD) screening. Relative MPI analysis was normal, whereas low-dose CT showed high calcium score. Myocardial blood flow and flow reserve were strongly impaired in all territories. Coronary angiograph...

Endoplasmic reticulum stress and proteasome pathway involvement in human podocyte injury with a truncated COL4A3 mutation.

Collagen type IV (COL4)-related nephropathy includes a variety of kidney diseases that occur with or without extra-renal manifestations caused by COL4A3-5 mutations. Previous studies revealed several novel mutations, including three COL4A3 missense mutations (G619R, G801R, and C1616Y) and the COL4A3 chr:228172489delA c.4317delA p.Thr1440ProfsX87 frameshift mutation that resulted in a truncated NC1 domain (hereafter named COL4A3 c.4317delA); however, the mutation mechanisms that lead to podocyte injury remai...

Current understanding of gut microbiota alterations and related therapeutic intervention strategies in heart failure.

The purpose of this review is to stress the complicated interactions between the microbiota and the development of heart failure. Moreover, the feasibility of modulating intestinal microbes and metabolites as novel therapeutic strategies is discussed.

Postoperative Respiratory Depression May Be Related to Undiagnosed Sleep-Disordered Breathing or Obstructive Sleep Apnea.

What can be done to decrease early deaths in people with severe mental disorders?

Early life stress: update on neurophysiologic effects and treatment.

Recent research on childhood trauma has focused on the effects of in-utero and early life stress (ELS) as well as improving access to care. This review includes the previous year's clinically relevant research with attention to gaps that require further research that should improve patient care.

Mitochondrial DNA Haplogroups and Delirium During Sepsis.

Studies suggest that mitochondrial dysfunction underlies some forms of sepsis-induced organ failure. We sought to test the hypothesis that variations in mitochondrial DNA haplogroup affect susceptibility to sepsis-associated delirium, a common manifestation of acute brain dysfunction during sepsis.

Intra-Abdominal Hypertension Is Responsible for False Negatives to the Passive Leg Raising Test.

To compare the passive leg raising test ability to predict fluid responsiveness in patients with and without intra-abdominal hypertension.

Effects of a Newly Developed Gratitude Intervention Program on Work Engagement among Japanese Workers: A Pre- and Post-Test Study.

This study aimed to develop a three-week gratitude intervention program that included gratitude lists and behavioral gratitude expression and to examine the effect of the program on work engagement, gratitude, self-efficacy, psychological distress, and job performance in a pretest-post-test study design.

Title / Question As An Occupational Medicine Provider, What are the Basics That I Need To Know About the Beryllium Lymphocyte Proliferation Test?

Refining Psychological, Substance Use, and Sociodemographic Predictors of Suicide Ideation and Attempts in a National Multiethnic Sample of Adults, 2008-2013.

The purpose of this study was to examine psychological, substance use, and sociodemographic predictors of 12-month suicide ideation and attempts across six US racial/ethnic groups-white, Latino/a, Black, Asian or Pacific Islander (A/PI), American Indian or Alaska Native (AI/AN), and multiracial adults. Multiple logistic regression analyses were conducted for 218,765 adults who participated in the 2008-2013 National Survey on Drug Use and Health. Overall, commonly cited factors were associated with increased...

A Randomized Controlled Trial Assessing the Efficacy of Group Psychological First Aid.

A randomized controlled trial assessed the efficacy of group psychological first aid (PFA) by comparing the Johns Hopkins RAPID-PFA model with a group conversation condition in 119 participants using the state version of State Trait Anxiety Scale and the Positive and Negative Affect Schedules. Both groups showed similar baseline scores, and after watching a distressing 5-minute video, both groups showed similar significant increases in state anxiety scores and negative affect scores, as well as similar decr...

The Association Between Child Abuse and Emotional and Behavioral Problems in Chinese School-Aged Boys With Attention Deficit Hyperactivity Disorder.

The aim of our study was to investigate the relationship between child abuse and emotional and behavioral problems in Chinese school-aged boys with attention deficit hyperactivity disorder (ADHD). Forty-eight school-aged boys with ADHD and 77 male healthy controls completed the final assessments that included the Child Behavior Checklist, the Barratt Impulsiveness Scale Version 11, the Screen for Child Anxiety Related Disorders, the Depression Self-Rating Scale for Children, and the Childhood Trauma Questio...

Reoperation for Urinary Incontinence After Retropubic and Transobturator Sling Procedures.

To compare the reoperation rates for recurrent stress urinary incontinence (SUI) after retropubic and transobturator sling procedures.

Challenges in the Diagnosis of Medulloblastoma Recurrence at an Unusual Site in a Patient With Prader-Willi Syndrome.

Medulloblastoma is the most common malignant pediatric brain tumor. Survival rates range between 50% and 80% depending on histology and other biological features, metastases, and treatment approach. Prader-Willi syndrome (PWS) is a genetically inherited disorder characterized by dysmorphic features, mental retardation, obesity, and hypogonadism among other features. We describe a 10.5-year-old girl with PWS and previous standard-risk medulloblastoma that relapsed in the pons 3 years after the end of treatme...

Noninvasive Methods For Assessing Inflammatory Bowel Disease Activity in Pregnancy: A Systematic Review.

Active inflammatory bowel disease (IBD) may increase the risk of adverse outcomes during pregnancy. Our aim was to systematically review the role of noninvasive fecal tests, such as fecal calprotectin (FCP) and lactoferrin (FL), and laboratory tests including C-reactive protein (CRP), hemoglobin, and albumin in the assessment of IBD during pregnancy. A systematic search of electronic databases was performed through October 2018 for studies assessing the utility of fecal and laboratory tests in predicting IB...


We systematically retested children with borderline-positive quantiferon (0.35-0.99 IU/mL) during the period 2015-2019. Among 647 tests, 27 (4%) were positive (>0.35 IU/mL). Borderline-positive quantiferon accounted for 10 of 27 (37%) positive tests. When retested, 9 of 10 (90%) were negative. Children younger than 5 years had negative tuberculin skin tests. Thus, we found high test variability in the borderline range and, in some children, high suspicion of false positive tests.

Yes…and! Actor Improvisation Enhances Psychiatric-Mental Health Nursing Education.

Based on a comparative dearth of simulation products to support the attainment of key skills in psychiatric-mental health nursing, the authors developed scripted scenarios to provide students with exposure to low-incidence/high-risk simulated clinical scenarios in the classroom setting. Acting students from the university's theater school were provided with character sketches and information on psychopathology-psychopharmacology to add a sense of authenticity to the performances. In turn, students questione...

Exam Wrappers: It Is Time to Adopt a Nursing Student Metacognitive Tool for Exam Review.

Examining test performance, a common practice in nursing education, can be a vital learning tool, as well as a means of assessment. Exam or cognitive wrappers, performed by students after an exam but before the exam review, can explicitly teach students to discern between what they do and what they do not know. The process teaches metacognition, the highest level of critical thinking. Nursing students need to be proficient in metacognition for professional growth well beyond the classroom. However, little i...

Role of Pattern Electroretinogram in Ocular Hypertension and Early Glaucoma.

To test if pattern electroretinogram (PERG) can early detect retinal ganglion cells dysfunction in ocular hypertension.

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