PubMed Journals Articles About "Mobius Bionics" RSS

17:54 EDT 20th July 2019 | BioPortfolio

Mobius Bionics PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Mobius Bionics articles that have been published worldwide.

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Showing "Mobius Bionics" PubMed Articles, all 8

Low density lipoprotein-inspired nanostructured lipid nanoparticles containing pro-doxorubicin to enhance tumor-targeted therapeutic efficiency.

Inefficient tumor accumulation and controlling drug release at the tumor site are two major obstacles limiting the antitumor efficacy of nanoparticle delivery systems. Inspired by the biological structure and function of low-density lipoprotein (LDL), a pH-sensitive ApoB-100/Oleic acid-DOX/NLC (AODN) nanoparticle based on nanostructured lipid carrier (NLC) was prepared in this study. The biological composition of ApoB-containing NLC nanoparticles is similar to that of LDL, which can effectively increase the...

3D bioprinting of hepatoma cells and application with microfluidics for pharmacodynamic test of Metuzumab.

Constructing in vitro drug models with a higher degree of bionics is considered to be an important approach to improve the effectiveness of existing drug screening models. 3D printing, co-culture and microfluidics are important methods that commonly used. This study combined the advantages of the three methods. A 3D co-culture microfluidic model with controllable hepatoma cluster size was constructed, and applied to pharmacodynamic tests of a new anti-CD147 monoclonal antibody, Metuzumab. In the phase of ce...

Applicability of vital staining and tissue clearing to vascular anatomy and melanocytes' evaluation of temporal bone in six laboratory species.

The purpose of the present study was to define the applicability of tissue clearing to the field of otology. We combined tissue clearing with vital staining perfusion via a pumping system to examine the vascular anatomy of temporal bones in laboratory animals. We used six different types of species including Korean wild mouse, mouse, Mongolian gerbil, hamsters and Guinea pigs. A mixture of Alcian blue reagent and 4% paraformaldehyde was circulated throughout the entire circulatory system of the animal via a...

Host Mesh Fitting of a Generic Musculoskeletal Model of the Lower Limbs to Subject-Specific Body Surface Data: A Validation Study.

Challenges remain in accurately capturing the musculoskeletal geometry of individual subjects for clinical and biomechanical gait analysis. The aim of this study was to use and validate the Host Mesh Fitting (HMF) technique for fitting a generic anatomically based musculoskeletal model to 3D body surface data of individual subjects. The HMF technique is based on the free-form idea of deforming geometrically complex structures according to the deformation of a surrounding volumetric mesh. Using the HMF techn...

Technological Transformation.

Technology has enabled bionics and artificial intelligence, each of which can have important applications in health care. As we continue to substitute body parts with machinery, however, we might wonder, "What makes us human?" This drawing interrogates the relationship between humanity and embodiment, specifically in neck and facial musculature and brain structures.

Validation of secondary dose calculation system with manufacturer-provided reference beam data using heterogeneous phantoms.

The Mobius3D (M3D) system (Mobius Medical Systems) is a second-check dosimetry system. We investigated the dose calculation accuracy of this system using heterogeneous phantoms with reference beam data provided by the manufacturer using simple and patient plans. We compared the dose distributions between M3D and the treatment planning system, as well as the measurements in solid water phantoms, heterogeneous phantoms, and patient plans for Varian and Elekta accelerators. The M3D results agreed well with the...

Development of High-Performance Soft Robotic Fish by Numerical Coupling Analysis.

To design a soft robotic fish with high performance by a biomimetic method, we are developing a soft robotic fish using piezoelectric fiber composite (PFC) as a flexible actuator. Compared with the conventional rigid robotic fish, the design and control of a soft robotic fish are difficult due to large deformation of flexible structure and complicated coupling dynamics with fluid. That is why the design and control method of soft robotic fish have not been established and they motivate us to make a further ...

Mechanism-Guided Scaffold Diversification: Perturbing and Trapping the Intermediates of Maltol-Type Cascade Claisen Rearrangement.

A mechanism-guided study to harness different kinds of active species in the cascade Claisen rearrangement for scaffold diversification has been developed. These robust and practical processes furnished a series of architectures with a large chemical space, varying from planar to three-dimensional. In addition, several interesting reactions were observed, such as [3 + 3] dimerization, quinone-based vinylogous Nazarov-type cyclization, and a rare 12e [σ2a + π2s + π2a + π2s + (π2a + π2s)] Mobius aromati...

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