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PubMed Journals Articles About "Amoxicillin Clavulanate Potassium" RSS

23:18 EST 23rd February 2020 | BioPortfolio

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Showing "Amoxicillin Clavulanate Potassium" PubMed Articles 1–25 of 709

Oral amoxicillin and amoxicillin-clavulanate: properties, indications, and usage.

Amoxicillin has been in use since the 1970s; it is the most widely used penicillin both alone and in combination with the beta-lactamase clavulanic acid.


Dual Therapy with Vonoprazan and Amoxicillin Is as Effective as Triple Therapy with Vonoprazan, Amoxicillin and Clarithromycin for Eradication of Helicobacter pylori.

Vonoprazan (VPZ) is the first clinically available potassium competitive acid blocker. This class of agents provides faster and more potent acid inhibition than proton pump inhibitors. Most strains of Helicobacter pylori are sensitive to amoxicillin. We hypothesized that dual therapy with VPZ and amoxicillin would provide the sufficient eradication rate for H. pylori infection. To evaluate this, we compared the eradication rate by the dual VPZ/amoxicillin therapy with that by the standard triple VPZ/amoxici...

Correlation Between Etest and Reference Broth Microdilution for Antimicrobial Susceptibility Testing of .

A three-center study was performed to see if Etest gradient diffusion minimum inhibitory concentration (MIC) methodology correlated with reference broth microdilution (BMD) for antimicrobial susceptibility testing of against six antimicrobial agents known to be usually effective against . This study was performed to assist in the decision-making process for possible deployment of the Etest method for antimicrobial susceptibility testing of into several regional public health laboratories in the United Sta...


Prevention of Postdental Procedure Bacteremia: A Network Meta-analysis.

Postdental procedure bacteremia is common and troublesome. The comparative efficacy of multiple prophylactic interventions is unclear. We compared the efficacy of interventions for the prevention of postdental procedure bacteremia. We conducted a review of ClinicalKey, Cochrane CENTRAL, Embase, ProQuest, PubMed, ScienceDirect, Web of Science, and ClinicalTrials.gov from inception to December 4, 2018. Randomized controlled trials that evaluated prophylactic interventions for the prevention of postdental proc...

Amoxicillin-Clavulanate Dosing in the Intensive Care Unit: The Additive Effect of Renal Replacement Therapy in a Patient with Normal Kidney Function.

Dosing of amoxicillin-clavulanic acid in critical illness is difficult as β-lactam pharmacokinetics are altered by physiological changes and therapies initiated in the intensive care unit such as renal replacement therapy (RRT). Successful treatment relies on sustaining a free antibiotic concentration above the minimum inhibitory concentration of the target pathogen (fT>MIC). We present a case of a patient treated with amoxicillin-clavulanic acid (1.2 g for 8 h) for an aspiration pneumonia. Dosing in this ...

Overcoming stability challenges during continuous intravenous administration of high-dose amoxicillin using portable elastomeric pumps.

While treatment of serious infectious diseases may require high-dose amoxicillin, continuous infusion may be limited by lack of knowledge regarding the chemical stability of the drug. Therefore, we have performed a comprehensive study so as to determine the chemical stability of high-dose amoxicillin solutions conducive to safe and effective continuous intravenous administration using portable elastomeric pumps. First, amoxicillin solubility in water was assessed within the range of 25 to 300 mg/mL. Then, a...

Amoxicillin removal by pre-denitrification membrane bioreactor (A/O-MBR): Performance evaluation, degradation by-products, and antibiotic resistant bacteria.

Membrane bioreactors (MBRs) are one of the treatment technologies with the potential to remove emerging compounds from wastewater. The present work evaluated the efficiency of an MBR pilot system in removing amoxicillin from synthetic wastewater using a continuous flow pre-denitrification MBR (A/O-MBR) pilot unit. The system operated in three phases: (1) synthetic wastewater and hydraulic retention time (HRT) of 40 h; (2) adding amoxicillin 100 μg L to the influent, and (3) varying flowrate to HRT of 20...

Sensitization of avian pathogenic Escherichia coli to amoxicillin in vitro and in vivo in the presence of surfactin.

The purpose of this study is to assess the antibiotics adjuvant effect of surfactin for boosting the treatment effect of amoxicillin. Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. In this study, we demonstrated that surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory conc...

Knowledge and attitude: two fundamental factors that determine patient compliance in antibiotic therapy.

Background With the development of infectious diseases, the use of antibiotics is increasing. Amoxicillin is a penicillin class of antibiotics that are widely used today. Compliance with amoxicillin can reduce the risk of microbial resistance. Two fundamental factors that determine patient compliance in antibiotic therapy are the patient's knowledge and attitude towards the antibiotic. In this study, we want to know the effect of knowledge and attitudes of patients on their compliance in using amoxicillin a...

Dietary sodium and potassium and risk of diabetes: A prospective study using data from the China Health and Nutrition Survey.

- Dietary sodium and potassium intakes are well-known risk factors for cardiovascular outcomes. However, the associations between dietary sodium and potassium and diabetes are still controversial. Our study aimed to examine whether dietary sodium, potassium and the sodium-potassium ratio are associated with the risk of diabetes, based on a large sample of Chinese adults.

Increased risk of acquisition and transmission of ESBL-producing Enterobacteriaceae in malnourished children exposed to amoxicillin.

Routine amoxicillin for children with uncomplicated severe acute malnutrition raises concerns of increasing antibiotic resistance. We performed an ancillary study nested within a double-blind, placebo-controlled trial in Niger testing the role of routine 7 day amoxicillin therapy in nutritional recovery of children 6 to 59 months of age with uncomplicated severe acute malnutrition.

MXene-Based Dendrite-Free Potassium Metal Batteries.

Potassium metal batteries are considered as attractive alternatives beyond lithium-ion batteries. However, uncontrollable dendrite growth on the potassium metal anode has restrained their practical applications. A high-performance potassium anode achieved by confining potassium metal into a titanium-deficient nitrogen-containing MXene/carbon nanotube freestanding scaffold is reported. The high electronic transport and fast potassium diffusion in this scaffold enable reduced local current density and homogen...

Effect of Dietary Potassium Restriction on Serum Potassium, Disease Progression, and Mortality in Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

Low-potassium diets are recommended to reduce serum potassium (Sk) and prevent complications of chronic kidney disease (CKD), but evidence underpinning this recommendation has not been systematically reviewed and synthesized. We conducted a systematic review comparing change in Sk, CKD progression, and mortality between those on a low-potassium versus unrestricted potassium diet.

The relationship between serum potassium concentrations and electrocardiographic characteristics in 163,547 individuals from primary care.

Potassium disturbances are common and associated with increased morbidity and mortality, even in patients without prior cardiovascular disease. We examined six electrocardiographic (ECG) measures and their association to serum potassium levels.

Efficacy of modified esomeprazole-amoxicillin dual therapies for Helicobacter pylori infection: an open-label, randomized trial.

The prevalence of Helicobacter pylori resistance to amoxicillin was less than 5% in most countries. Proton pump inhibitor (PPI)-amoxicillin dual therapy dosing four times daily (q.i.d.) for 14 days could achieve an eradication rate of more than 85%. It is unclear whether dual therapy with shorter treatment duration or lower dosing frequency could also attain a satisfactory cure rate. We conducted a randomized controlled trial to assess the efficacy and safety of two modified esomeprazole-amoxicillin dual ...

Mycobacterium chelonae infection mimicking demodex folliculitis.

A 69-year-old man was admitted to hospital with a three month history of a diffuse eruption of painful crusted erythematous papulopustular lesions involving the face and neck. His medical history included chronic lymphocytic leukaemia on monthly intravenous immunoglobulin infusions, type 2 diabetes mellitus and a previous fungal lung abscess for which he was on prophylactic posaconazole. The eruption had not responded to two weeks of amoxicillin-clavulanate started by his general practitioner. By then, he h...

Factors associated with urinary sodium/potassium ratio in participants in the ELSA-Brazil study.

This study aimed to identify sociodemographic factors associated with high estimated sodium/potassium ratio. A total of 15,105 participants were assessed, from 35 to 74 years of age, from a cohort of public employees (ELSA-Brazil). Socioeconomic data were collected with a questionnaire, and 12-hour nighttime urine samples were collected to estimate sodium and potassium intake. Sodium/potassium ratio was calculated in mmol/L and divided into tertiles: 1st tertile, corresponding to "low"; 2nd tertile for "med...

Racial and Ethnic Differences in Mortality Associated with Serum Potassium in Incident Peritoneal Dialysis Patients.

Abnormalities in serum potassium are risk factors for sudden cardiac death and arrhythmias among dialysis patients. Although a previous study in hemodialysis patients has shown that race/ethnicity may impact the relationship between serum potassium and mortality, the relationship remains unclear among peritoneal dialysis (PD) patients where the dynamics of serum potassium is more stable.

Impact of oral amoxicillin and amoxicillin/clavulanic acid treatment on bacterial diversity and β-lactam resistance in the canine faecal microbiota.

Aminopenicillins with or without a β-lactamase inhibitor are widely used in both human and veterinary medicine. However, little is known about their differential impact on the gut microbiota and development of antimicrobial resistance.

Mechanistic and ecotoxicological studies of amoxicillin removal through anaerobic degradation systems.

Many studies have been conducted on the evaluation and monitoring of micropollutants and by-products in wastewater treatment plants. Considering the increase in the production and consumption of emerging contaminants, such as drugs, personal care products, and plasticisers, it is necessary to conduct studies that support the elaboration of laws and regulations that promote the environmentally sustainable use of sludge and effluents. In this work, the biological degradation of amoxicillin was studied under t...

Risk of Adverse Reactions to Oral Antibiotics Prescribed by Dentists.

Dentists prescribe a large portion of all oral antibiotics, and these are associated with a risk of adverse drug reactions (ADRs). The aim of this study was to quantify the risk of ADRs associated with oral antibiotics commonly prescribed by dentists. NHS Digital Prescribing data and Yellow Card Drug Analysis data for 2010 to 2017 were abstracted to quantify dental antibiotic prescribing in England, and the rate and types of ADRs associated with them. During the period of study, the mean number of actively ...

Association between potassium concentrations, variability and supplementation, and in-hospital mortality in ICU patients: a retrospective analysis.

Serum potassium concentrations are commonly between 3.5 and 5.0 mmol/l. Standardised protocols for potassium range and supplementation in the ICU are lacking. The purpose of this retrospective analysis of ICU patients was to investigate potassium concentrations, variability and supplementation, and their association with in-hospital mortality.

Eliminating partial-transformation products and mitigating residual toxicity of amoxicillin through intimately coupled photocatalysis and biodegradation.

Intimately coupled photocatalysis and biodegradation (ICPB) is a promising technology for treating wastewater containing antibiotics. While past work has documented the benefits of ICPB for removing and mineralizing antibiotics, its impacts on mitigating biotoxicity from products has not been studied. We fabricated an ICPB carrier by coating Ag-doped TiO on the outer skeleton of sponge carriers and allowing biofilm to grow in the internal macro-pores. We used amoxicillin (CHNOS) as the model antibiotic. The...

Water relations of two Sicilian grapevine cultivars in response to potassium availability and drought stress.

We investigated the response of two Sicilian grapevine cultivars, Catarratto and Nero d'Avola, to potassium deficiency and drought stress. Two-year-old plants grafted on 1103 Paulsen were grown in agriperlite, with or without potassium in the fertigation solution for six weeks, and subjected to moderate drought stress by suspending irrigation for one week. Potassium content of leaves, roots and xylem sap were measured with an ion-selective electrode. Changes in stomatal conductance, stem and leaf water pote...

Extended-spectrum resistance to β-lactams/β-lactamase inhibitors (ESRI) evolved from low-level resistant Escherichia coli.

Escherichia coli is characterized by three resistance patterns to β-lactams/β-lactamase inhibitors (BLs/BLIs): (i) resistance to ampicillin/sulbactam and susceptibility to amoxicillin/clavulanic acid and piperacillin/tazobactam (RSS); (ii) resistance to ampicillin/sulbactam and amoxicillin/clavulanic acid, and susceptibility to piperacillin/tazobactam (RRS); and (iii) resistance to ampicillin/sulbactam, amoxicillin/clavulanic acid and piperacillin/tazobactam (RRR). These resistance patterns are acquired c...


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