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PubMed Journals Articles About "Amphinex TPCS2a Bleomycin Illumination With CeramOptec Laser Head" RSS

19:12 EDT 20th October 2018 | BioPortfolio

Amphinex TPCS2a Bleomycin Illumination With CeramOptec Laser Head PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Amphinex TPCS2a Bleomycin Illumination With CeramOptec Laser Head articles that have been published worldwide.

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Showing "Amphinex TPCS2a Bleomycin Illumination with CeramOptec laser Head" PubMed Articles 1–25 of 4,400+

Lymphangioma circumscriptum treated with combination of Bleomycin sclerotherapy and Radiofrequency ablation.

Lymphangioma circumscriptum (LC) is a lymphatic malformation presenting with vesiculo-papules or warty lesions, resembling a "frog-spawn". Many treatment modalities have been described but random excision is still often needed. Bleomycin is a safe sclerosant with specific action on the vascular endothelial cells. It has been used extensively in cystic hygromas but its use in LC of the skin has not been documented previously. We present this case with extensive LC of the flank treated with a combination of i...


A new three-dimensional nonscanning laser imaging system based on the illumination pattern of a point-light-source array.

One of the most important goals of research on three-dimensional nonscanning laser imaging systems is the improvement of the illumination system. In this paper, a new three-dimensional nonscanning laser imaging system based on the illumination pattern of a point-light-source array is proposed. This array is obtained using a fiber array connected to a laser array with each unit laser having independent control circuits. This system uses a point-to-point imaging process, which is realized using the exact corr...

Electrochemotherapy with cisplatin or bleomycin in head and neck squamous cell carcinoma: Improved effectiveness of cisplatin in HPV-positive tumors.

Human papillomavirus (HPV) is an important etiological factor in head and neck squamous cell carcinomas (SCCs). Standard treatment of HPV-positive tumors with platinum-based radio(chemo)therapy results in a better outcome than in HPV-negative tumors. Electrochemotherapy is becoming an increasingly recognized mode of treatment in different cancers; thus, its use in the management of head and neck SCC is of considerable interest. However, response to electrochemotherapy according to HPV status of the tumors h...


Strehl ratio for optical systems with ultrafast illumination.

We study ultrafast laser pulse properties as they propagate through optical systems. A modified definition of Strehl ratio is used to quantify the chromatic and temporal behavior of ultrafast laser pulses at the optical focus. We propose this parameter as a figure of merit for the design and analysis of optical systems with ultrafast illumination. A simple method to obtain approximate numerical solutions is given with the help of ray tracing software. Effects of monochromatic aberrations and material disper...

On the role of interference in laser-based mid-infrared widefield microspectroscopy.

A laser's high degree of coherence leads to interferences, which - in the absence of precautions - can cause severe image distortions such as fringes and speckles and which thereby strongly hamper a meaningful interpretation of hyperspectral images in laser-based widefield microspectroscopy. While images and spectra of homogenous samples may already suffer from interferences, any structured object such as a tissue thin section will add to these distortions due to wavelength- and, in particular, sample-depen...

Rare-earth fluorescence thermometry of laser-induced plasmon heating in silver nanoparticles arrays.

The laser-induced plasmon heating of an ordered array of silver nanoparticles, under continuous illumination with an Ar laser, was probed by rare-earth fluorescence thermometry. The rise in temperature in the samples was monitored by measuring the temperature-sensitive photoluminescent emission of a europium complex (EuTTA) embedded in PMMA thin-films, deposited onto the nanoparticles array. A maximum temperature increase of 19 °C was determined upon resonant illumination with the surface plasmon resonan...

Combined Nd:YAG laser and bleomycin sclerotherapy under the same anesthesia for cervicofacial venous malformations: A safe and effective treatment option.

Extensive cervicofacial venous malformations (VM) pose significant challenges to a patient's quality of life (altered breathing, dysphagia, dysarthria). Treatment options include: 1) Surgical debulking; 2) Sclerotherapy; 3) laser therapy; or 4) Combined modalities. Recent studies have demonstrated the importance of multimodality and multidisciplinary management of these patients. However, no studies have described combined single anesthetic laser and sclerotherapy treatment. We sought to demonstrate the saf...

Co-delivery of docetaxel and disulphonate tetraphenyl chlorin in one nanoparticle produces strong synergism between chemo- and photodynamic therapy in drug-sensitive and -resistant cancer cells.

Cancer therapies based on the combinations of different drugs and/or treatment modalities are emerging as important strategies for increasing efficacy and cure, decreasing unwanted toxicity and overcoming drug resistance, provided that optimized drug concentration ratios are delivered into the target tissue. To these purposes, delivery systems such as nanoparticles (NPs), offer the unique opportunity to finely tune the drug loading and the release rate of drug combinations in the target tissues. Here, we pr...

Ultrafast smoothing scheme for improving illumination uniformities of laser quads.

The beam smoothing technology, smoothing by spectral dispersion, plays an important role in improving the illumination uniformities of the lasers in inertial confinement fusion facilities. However, due to the limitations of the modulation frequency of the electro-optic modulator, the uniformity of the lasers approaches an asymptotic value after tens of picoseconds that are much longer than the response time of laser plasma instabilities. To the best of our knowledge, this is the first time that an ultrafast...

Optically-active metastable defects in volumetric nanoplasmonic composites.

Metastable defects in semiconductor materials have been well known for decades, but have only recently started to attract attention for their potential applications in information technology. Here, we describe active and passive nanoplasmonic materials with optically active metastable defects that can be switched on or off by cooling with or without laser illumination, respectively. To the best of our knowledge, this is the first report of metastable defects in either passive or active nanoplasmonic materia...

Use of percutaneous bleomycin sclerotherapy for orbital lymphatic malformations.

Bleomycin sclerotherapy has been shown to be a viable treatment for lymphatic malformations. However, its use for these lesions confined to the orbit is becoming increasingly documented in the literature. In this study, we summarize the clinical manifestations and outcomes observed following percutaneous bleomycin sclerotherapy for orbital lymphatic malformation.

Utility of Optical Coherence Tomography for Guiding Laser Therapy Among Patients With Recurrent Respiratory Papillomatosis.

Recurrent respiratory papillomatosis (RRP) is a viral-induced disease caused by human papillomavirus and the second leading cause of dysphonia in children; however, neither a cure nor a definitive surgical treatment is currently available for RRP. Although laser therapy is often used in the treatment of RRP, the lack of real-time laser-tissue interaction feedback undermines the ability of physicians to provide treatments with low morbidity. Therefore, an intraoperative tool to monitor and control laser trea...

All-fiber laser with flattop beam output using a few-mode fiber Bragg grating.

We report a novel method of beam shaping in an all-fiber laser. Flattop beams are first generated from the all-fiber laser using a few-mode fiber Bragg grating by superposing the fundamental mode (LP) with a solid central beam distribution, and the second-order mode (LP) gives rise to a donut-shape beam distribution. Two modes are obtained in the fiber laser simultaneously, and the wavelengths of the two modes are 1053.7 nm and 1055.4 nm, respectively. An experiment has been carried out, and a high-qualit...

Intraoperative Fluorescence Cerebral Angiography by Laser Surgical Microscopy: Comparison With Xenon Microscopy and Simultaneous Observation of Cerebral Blood Flow and Surrounding Structures.

Laser surgical microscopes should enable uniform illumination of the operative field, and require less luminous energy compared with existing xenon surgical microscopes.

Temperature Rise under Two-Photon Optogenetic Brain Stimulation.

In recent decades, optogenetics has been transforming neuroscience research, enabling neuroscientists to drive and read neural circuits. The recent development in illumination approaches combined with two-photon (2P) excitation, either sequential or parallel, has opened the route for brain circuit manipulation with single-cell resolution and millisecond temporal precision. Yet, the high excitation power required for multi-target photostimulation, especially under 2P illumination, raises questions about the ...

Hot topics from the Assemblies.

Tissue-resident alveolar macrophages (TR-AM) are depleted from the lung during the early stages of bleomycin-induced lung injury and fibrosis. The recovery of the population of macrophages after bleomycin could be completely attributable to the recruitment and differentiation of monocyte-derived alveolar macrophages (Mo-AM). The authors used multiple lineage-trace mouse models where they selectively depleted TR-AM or Mo-AM and induced fibrosis with bleomycin. Deletion of TR-AM had no effect on the severity ...

Inhibition of mTOR ameliorated bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition.

Epithelial-mesenchymal transition (EMT) plays a pivotal role in idiopathic pulmonary fibrosis (IPF). In bleomycin-induced pulmonary fibrosis mice, we observed that inhibition of mTOR (mammalia target of rapamycin) attenuated IPF. Rapamycin suppressed the down-regulation of E-cadherin and up-regulation of fibronectin in bleomycin-induced pulmonary fibrosis mice. In addition, dual immunofluorescence staining for E-cadherin and fibronectin demonstrated that rapamycin pretreatment decreased the proportions of A...

On-Demand Generation of Neutral and Negatively Charged Silicon-Vacancy Centers in Diamond.

Point defects in wide-band-gap semiconductors are emerging as versatile resources for nanoscale sensing and quantum information science, but our understanding of the photoionization dynamics is presently incomplete. Here, we use two-color confocal microscopy to investigate the dynamics of charge in type 1b diamond hosting nitrogen-vacancy (NV) and silicon-vacancy (SiV) centers. By examining the nonlocal fluorescence patterns emerging from local laser excitation, we show that, in the simultaneous presence of...

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow.

To use laser speckle flowgraphy (LSFG) to assess blood flow (BF) in the optic nerve head (ONH) tissue and choroid during elevated intraocular pressure (IOP).

Vascularization of the Tumours Affects the Pharmacokinetics of Bleomycin and the Effectiveness of Electrochemotherapy.

Pre-clinical and clinical data indicate differences in the responses of melanoma and carcinoma tumours to electrochemotherapy. The purpose of this study was to investigate the origin of this difference, whether it is due to the intrinsic difference in tumour cell susceptibility to the chemotherapeutic, or due to the tumour microenvironment. For this purpose, we performed a pre-clinical study in B16F1 melanoma and TS/A carcinoma tumours in mice, in which the anti-tumour effectiveness of electrochemotherapy w...

Myocardial infarction in a young patient with seminoma during chemotherapy with cisplatinum, etoposide, and bleomycin.

 More than 90 % of all patients with testicular germ cell tumours can be cured effectively. The mainstay of treatment is chemotherapy with cisplatin, etoposide and bleomycin (PEB). This regimen is usually well tolerated and does not lead to serious adverse events. Cardiovascular complications are encountered very rarely, but have gained increasing attention in recent years.

2.1  μm composite Tm/Ho:YAG laser.

We realize Ho laser operation in a composite Tm/Ho:YAG gain medium for the first time, to the best of our knowledge, which was integrated via diffusion bonding the Tm-doped and Ho-doped crystals into a single bulk structure. A maximum output power around 6 W was obtained with a slope efficiency of 40.1% and conversion efficiency (CE) of 33.6% from the absorbed 785 nm laser diode to 2122 nm Ho laser, which is comparable with CE in 1.9 μm LD pumped Ho lasers. Such a scheme is demonstrated to be another v...

Modular Nanotransporter with P21 Fragment Inhibits DNA Repair after Bleomycin Treatment.

Modular nanotransporter (MNT) with C-terminal fragment of the p21 protein was synthesized and characterized, and its effect on DNA lesions was studied. This p21 fragment in MNT can significantly inhibit DNA repair in A431 human carcinoma cells after bleomycin treatment.

Dihydroartemisinin alleviates oxidative stress in bleomycin-induced pulmonary fibrosis.

Dihydroartemisinin has been shown to inhibit the development of pulmonary fibrosis in rats, but its mechanism has yet to be elucidated. This study aimed to determine the mechanisms of dihydroartemisinin in bleomycin-induced pulmonary fibrosis in a rat model.

Therapeutic effect and mechanism of carboxyamidotriazole on the pulmonary fibrosis of mice induced by bleomycin.

To investigate the treatment effect of carboxyamidotriazole (CAI) on bleomycin induced lung fibrosis in mice, and the potential mechanism involved.A total of 45 mice were divided into three groups randomly. Blank control group (blank group): after a one-time tail vein injection of saline solution 0.2 ml, mice were given polyethylene glycol 400 (PEG-400) 0.1 ml/10 g by gavage once daily for 14 days; the bleomycin group (BLM group): after a one-time tail vein injection of bleomycin 150 mg/kg, mice were given ...


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