PubMed Journals Articles About "Amphinex TPCS2a Bleomycin Illumination With CeramOptec Laser Head" RSS

11:41 EST 14th December 2018 | BioPortfolio

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Showing "Amphinex TPCS2a Bleomycin Illumination with CeramOptec laser Head" PubMed Articles 1–25 of 4,400+

Lymphangioma circumscriptum treated with combination of Bleomycin sclerotherapy and Radiofrequency ablation.

Lymphangioma circumscriptum (LC) is a lymphatic malformation presenting with vesiculo-papules or warty lesions, resembling a "frog-spawn". Many treatment modalities have been described but random excision is still often needed. Bleomycin is a safe sclerosant with specific action on the vascular endothelial cells. It has been used extensively in cystic hygromas but its use in LC of the skin has not been documented previously. We present this case with extensive LC of the flank treated with a combination of i...

A new three-dimensional nonscanning laser imaging system based on the illumination pattern of a point-light-source array.

One of the most important goals of research on three-dimensional nonscanning laser imaging systems is the improvement of the illumination system. In this paper, a new three-dimensional nonscanning laser imaging system based on the illumination pattern of a point-light-source array is proposed. This array is obtained using a fiber array connected to a laser array with each unit laser having independent control circuits. This system uses a point-to-point imaging process, which is realized using the exact corr...

Electrochemotherapy with cisplatin or bleomycin in head and neck squamous cell carcinoma: Improved effectiveness of cisplatin in HPV-positive tumors.

Human papillomavirus (HPV) is an important etiological factor in head and neck squamous cell carcinomas (SCCs). Standard treatment of HPV-positive tumors with platinum-based radio(chemo)therapy results in a better outcome than in HPV-negative tumors. Electrochemotherapy is becoming an increasingly recognized mode of treatment in different cancers; thus, its use in the management of head and neck SCC is of considerable interest. However, response to electrochemotherapy according to HPV status of the tumors h...

Strehl ratio for optical systems with ultrafast illumination.

We study ultrafast laser pulse properties as they propagate through optical systems. A modified definition of Strehl ratio is used to quantify the chromatic and temporal behavior of ultrafast laser pulses at the optical focus. We propose this parameter as a figure of merit for the design and analysis of optical systems with ultrafast illumination. A simple method to obtain approximate numerical solutions is given with the help of ray tracing software. Effects of monochromatic aberrations and material disper...

Rare-earth fluorescence thermometry of laser-induced plasmon heating in silver nanoparticles arrays.

The laser-induced plasmon heating of an ordered array of silver nanoparticles, under continuous illumination with an Ar laser, was probed by rare-earth fluorescence thermometry. The rise in temperature in the samples was monitored by measuring the temperature-sensitive photoluminescent emission of a europium complex (EuTTA) embedded in PMMA thin-films, deposited onto the nanoparticles array. A maximum temperature increase of 19 °C was determined upon resonant illumination with the surface plasmon resonan...

Co-delivery of docetaxel and disulphonate tetraphenyl chlorin in one nanoparticle produces strong synergism between chemo- and photodynamic therapy in drug-sensitive and -resistant cancer cells.

Cancer therapies based on the combinations of different drugs and/or treatment modalities are emerging as important strategies for increasing efficacy and cure, decreasing unwanted toxicity and overcoming drug resistance, provided that optimized drug concentration ratios are delivered into the target tissue. To these purposes, delivery systems such as nanoparticles (NPs), offer the unique opportunity to finely tune the drug loading and the release rate of drug combinations in the target tissues. Here, we pr...

Ultrafast smoothing scheme for improving illumination uniformities of laser quads.

The beam smoothing technology, smoothing by spectral dispersion, plays an important role in improving the illumination uniformities of the lasers in inertial confinement fusion facilities. However, due to the limitations of the modulation frequency of the electro-optic modulator, the uniformity of the lasers approaches an asymptotic value after tens of picoseconds that are much longer than the response time of laser plasma instabilities. To the best of our knowledge, this is the first time that an ultrafast...

Optically-active metastable defects in volumetric nanoplasmonic composites.

Metastable defects in semiconductor materials have been well known for decades, but have only recently started to attract attention for their potential applications in information technology. Here, we describe active and passive nanoplasmonic materials with optically active metastable defects that can be switched on or off by cooling with or without laser illumination, respectively. To the best of our knowledge, this is the first report of metastable defects in either passive or active nanoplasmonic materia...

Hybrid multi-wavelength nonlinear photoacoustic sensing and imaging.

Multi-wavelength photoacoustic (PA) imaging has been studied extensively to explore the spectroscopic absorption contrast of biological tissues. To generate strong PA signals, a high-power wavelength tunable pulsed laser source has to be employed, which is bulky and quite expensive. In this Letter, we propose a hybrid multi-wavelength PA imaging (hPAI) method based on the combination of a single-wavelength pulsed laser source and multi-wavelength continuous-wave (CW) laser sources. By carefully controlling ...

Use of percutaneous bleomycin sclerotherapy for orbital lymphatic malformations.

Bleomycin sclerotherapy has been shown to be a viable treatment for lymphatic malformations. However, its use for these lesions confined to the orbit is becoming increasingly documented in the literature. In this study, we summarize the clinical manifestations and outcomes observed following percutaneous bleomycin sclerotherapy for orbital lymphatic malformation.

Utility of Optical Coherence Tomography for Guiding Laser Therapy Among Patients With Recurrent Respiratory Papillomatosis.

Recurrent respiratory papillomatosis (RRP) is a viral-induced disease caused by human papillomavirus and the second leading cause of dysphonia in children; however, neither a cure nor a definitive surgical treatment is currently available for RRP. Although laser therapy is often used in the treatment of RRP, the lack of real-time laser-tissue interaction feedback undermines the ability of physicians to provide treatments with low morbidity. Therefore, an intraoperative tool to monitor and control laser trea...

Factors of local recurrence and organ preservation with transoral laser microsurgery in laryngeal carcinomas; CHAID decision-tree analysis.

Indications of transoral laser microsurgery (TLM) are conditioned by the risk of local relapse.

Intraoperative Fluorescence Cerebral Angiography by Laser Surgical Microscopy: Comparison With Xenon Microscopy and Simultaneous Observation of Cerebral Blood Flow and Surrounding Structures.

Laser surgical microscopes should enable uniform illumination of the operative field, and require less luminous energy compared with existing xenon surgical microscopes.

Temperature Rise under Two-Photon Optogenetic Brain Stimulation.

In recent decades, optogenetics has been transforming neuroscience research, enabling neuroscientists to drive and read neural circuits. The recent development in illumination approaches combined with two-photon (2P) excitation, either sequential or parallel, has opened the route for brain circuit manipulation with single-cell resolution and millisecond temporal precision. Yet, the high excitation power required for multi-target photostimulation, especially under 2P illumination, raises questions about the ...

Sequential transmission electron microscopy observation of the shape change of gold nanorods under pulsed laser light irradiation.

In situ sequential high-resolution observations were performed on gold nanorods under near-infra-red pulsed laser irradiation using a high-voltage electron microscope attached to a pulsed laser illumination system. The original nanorods were single crystals; the longer axes were oriented along [001]. Under laser light irradiation with λ = 1064 nm with an average intensity per pulse of 980 or 490 J/m2, the shape of the nanorods changed from rod to barrel surrounded by the {111} and {001} facets, while the o...

Active optical modulator based on a metasurface in the terahertz region.

The characteristics of the electromagnetically induced transparency (EIT) analog exposed under different illumination powers have been investigated theoretically and experimentally. The EIT analog is composed of a fixed aluminum structure fabricated on the silicon substrate. It was found that the resonance degree of the transparent window displayed a decreasing trend, and a blueshift phenomenon emerged by increasing the powers of the laser. Similarly, the properties of the time delay under different illumin...

Hot topics from the Assemblies.

Tissue-resident alveolar macrophages (TR-AM) are depleted from the lung during the early stages of bleomycin-induced lung injury and fibrosis. The recovery of the population of macrophages after bleomycin could be completely attributable to the recruitment and differentiation of monocyte-derived alveolar macrophages (Mo-AM). The authors used multiple lineage-trace mouse models where they selectively depleted TR-AM or Mo-AM and induced fibrosis with bleomycin. Deletion of TR-AM had no effect on the severity ...

Inhibition of mTOR ameliorated bleomycin-induced pulmonary fibrosis by regulating epithelial-mesenchymal transition.

Epithelial-mesenchymal transition (EMT) plays a pivotal role in idiopathic pulmonary fibrosis (IPF). In bleomycin-induced pulmonary fibrosis mice, we observed that inhibition of mTOR (mammalia target of rapamycin) attenuated IPF. Rapamycin suppressed the down-regulation of E-cadherin and up-regulation of fibronectin in bleomycin-induced pulmonary fibrosis mice. In addition, dual immunofluorescence staining for E-cadherin and fibronectin demonstrated that rapamycin pretreatment decreased the proportions of A...

The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow.

To use laser speckle flowgraphy (LSFG) to assess blood flow (BF) in the optic nerve head (ONH) tissue and choroid during elevated intraocular pressure (IOP).

Myocardial infarction in a young patient with seminoma during chemotherapy with cisplatinum, etoposide, and bleomycin.

 More than 90 % of all patients with testicular germ cell tumours can be cured effectively. The mainstay of treatment is chemotherapy with cisplatin, etoposide and bleomycin (PEB). This regimen is usually well tolerated and does not lead to serious adverse events. Cardiovascular complications are encountered very rarely, but have gained increasing attention in recent years.

Modular Nanotransporter with P21 Fragment Inhibits DNA Repair after Bleomycin Treatment.

Modular nanotransporter (MNT) with C-terminal fragment of the p21 protein was synthesized and characterized, and its effect on DNA lesions was studied. This p21 fragment in MNT can significantly inhibit DNA repair in A431 human carcinoma cells after bleomycin treatment.

Dihydroartemisinin alleviates oxidative stress in bleomycin-induced pulmonary fibrosis.

Dihydroartemisinin has been shown to inhibit the development of pulmonary fibrosis in rats, but its mechanism has yet to be elucidated. This study aimed to determine the mechanisms of dihydroartemisinin in bleomycin-induced pulmonary fibrosis in a rat model.

Illumination uniformity improvement in digital micromirror device based scanning photolithography system.

Illumination uniformity in photolithography systems determines the dimensional difference across the entire lithographic substrate. However, traditional lithography system relies on expensive and complex illumination system for achieving uniform illumination. In this paper, we propose a simple and cost-effective method based on the modulation of digital micromirror device to improve illumination uniformity. The modulation according to a digital mask achieved via an iteration program improves the uniformity ...

2-Pyridone-functionalized Aza-BODIPY photosensitizer for imaging-guided sustainable phototherapy.

To overcome irradiation-dependence of cancer phototherapy, a near infrared aza-BODIPY-based photothermogenic photosensitizer BDY with 2-Pyridone group has been synthesized for imaging-guided photothermal synergistic sustainable photodynamic therapy. Multifunctional water-soluble BDY nanoparticles (NPs), with high photothermal conversion efficiency of 35.7% and excellent singlet oxygen (O) generation ability, are prepared by self-assembling. The reversible transformation between 2-pyridone moiety and its end...

Contact Mechanics of Anatomic Radial Head Prosthesis: Comparison Between Native Radial Head and Anatomic Radial Head Prostheses in the Dynamic Mode.

The biomechanical characteristics of anatomic radial head prostheses have not been completely investigated. We compared and analyzed the contact kinematic characteristics of the native radial head and radial head prostheses replicating the native head contour, using a real-time flexion simulation model.

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