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PubMed Journals Articles About "Automated Detection Multidirectional Compensatory Balance Reactions Step Towards" RSS

18:09 EST 20th January 2020 | BioPortfolio

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Showing "Automated detection multidirectional compensatory balance reactions step towards" PubMed Articles 1–25 of 15,000+

Automated detection of multidirectional compensatory balance reactions: a step towards tracking naturally-occurring near-falls.

Falls are the leading cause of fatal and non-fatal injuries among seniors with serious and costly consequences. Laboratory evidence supports the view that impaired ability to execute compensatory balance reactions (CBRs) or near-falls is linked to an increased risk of falling. Therefore, as an alternative to the commonly used fall risk assessment methods examining spatial-temporal parameters of gait, this study focuses on the development of machine learning-based models to detect multidirectional CBRs using...


Age-related changes in the capacity to select early-onset upper-limb reactions to either recover balance or protect against impact.

Falling is a leading cause of serious injury, loss of independence and nursing home admission in seniors. Arm reactions evoked by sudden loss of balance can play an important role in preventing falls and protecting against injury. The aim of this study was to investigate the effect of unpredictable perturbation characteristics on perturbation-triggered early-onset balance-recovery and impact-protection arm reactions. Twelve healthy young adults (20-28 yrs.; 5 women) and twelve healthy older adults (65-74...

A novel dye-based colorimetric chemosensors for sequential detection of Cu and cysteine in aqueous solution.

An IDAs based chemosensing ensembles for sensitive and selective sequential detection of Cu and cysteine (Cys) in 100% aqueous solution was designed on the basis of the complex formation between 4-(2-Pyridylazo)resorcinol (PAR). In the first step, PAR was used for colorimetric detection of Cu in aqueous solution by the obvious color change. The detection limit (31.0 nmol L) for Cu much lower than the guideline (31.5 μmol L) of WHO in drinking water. In the second step the produced ensemble (PAR-Cu)...


A fully automated sample-to-answer PCR system for easy and sensitive detection of dengue virus in human serum and mosquitos.

The insulated isothermal PCR (iiPCR) technology enables consistent PCR amplification and detection in a simple heating device. A pan-dengue virus (DENV) RT-iiPCR, targeting the 5' untranslated region, was validated previously on the semi-automated POCKIT combo system (involving separate devices for nucleic acid extraction and PCR amplification/detection) to offer performance comparable to a laboratory real-time PCR. Working on the same technologies, a compact automated sample-in-answer-out system (POCKIT Ce...

The cross-sectional relationships between age, standing static balance, and standing dynamic balance reactions in typically developing children.

Static balance performance is a common metric for evaluating the development of postural control in children. Less is known about the potentially independent development of dynamic balance performance.

Automated spectrographic seizure detection using convolutional neural networks.

Non-convulsive seizures are common in critically ill patients, and delays in diagnosis contribute to increased morbidity and mortality. Many intensive care units employ continuous EEG (cEEG) for seizure monitoring. Although cEEG is continuously recorded, it is often reviewed intermittently, which may delay seizure diagnosis and treatment. This may be mitigated with automated seizure detection. In this study, we develop and evaluate convolutional neural networks (CNN) to automate seizure detection on EEG spe...

No substantial change in the balance between model-free and model-based control via training on the two-step task.

Human decisions can be habitual or goal-directed, also known as model-free (MF) or model-based (MB) control. Previous work suggests that the balance between the two decision systems is impaired in psychiatric disorders such as compulsion and addiction, via overreliance on MF control. However, little is known whether the balance can be altered through task training. Here, 20 healthy participants performed a well-established two-step task that differentiates MB from MF control, across five training sessions. ...

A simple and programmed DNA tweezer probes for one-step and amplified detection of UO.

A simple DNA tweezer was proposed for one-step and amplified detection of UO based on DNAzyme catalytic cleavage. The two arms of DNA tweezers are close in the original form. Thus, the fluorescent signal of fluorophore at the end of arm is dramatically quenched. However, the structure of DNA tweezers can be changed from "close" to "open" in the presence of UO, resulting the strong fluorescent signal. The linear range was obtained in the range of 0.1 nM to 60 nM and the limit of detection was 25 pM with th...

An Automated Microrobotic Platform for Rapid Detection of C. diff Toxins.

Clostridium difficile (C. diff) infection leads to hundreds of nosocomial infections, and early diagnosis of this toxin-mediated disease is important. This paper aims to develop a microrobotic system and related methods that enable the automated and rapid detection of toxins secreted by C. diff that exist in patient's stool.

Rapid Chemical Reaction Monitoring by Digital Microfluidics-NMR: Proof of Principle Towards an Automated Synthetic Discovery Platform.

Microcoil Nuclear magnetic resonance (NMR) has been interfaced with digital microfluidics (DMF) and is applied to monitor organic reactions in organic solvents as a proof of concept. DMF permits droplets to be moved and mixed inside the NMR to initiate reactions while using sub-microliter volumes of reagent, opening up the potential to follow the reactions of scarce or expensive reagents. By setting up the spectrometer shims on a reagent droplet, data acquisition can be started immediately upon droplet mixi...

Deep learning algorithms for automated detection of Crohn's disease ulcers by video capsule endoscopy.

The aim of our study was to develop and evaluate a deep learning algorithm for the automated detection of small-bowel ulcers in Crohn's disease (CD) on capsule endoscopy )CE( images of individual patients.

Wearable biomolecule smartsensors based on one-step fabricated berlin green printed arrays.

The wearable smart detection of body biomolecules and biomarkers is being of significance in the practical fields. Hydrogen peroxide (HO) is a product of some enzyme-catalyzed biomolecular reactions. The detection of HO could reflect the concentration information of the enzyme reaction biomolecule substrate such as glucose. A high-performance berlin green (BG) carbon ink for monitoring HO was prepared in this work. And we have successfully developed the wearable smartsensors for detecting HO and glucose bas...

Evaluation of KRAS, NRAS and BRAF mutations detection in plasma using an automated system for patients with metastatic colorectal cancer.

Cell-free DNA detection is becoming a surrogate assay for tumor genotyping. Biological fluids often content a very low amount of cell-free tumor DNA and assays able to detect very low allele frequency mutant with a few quantities of DNA are required. We evaluated the ability of the fully-automated molecular diagnostics platform Idylla for the detection of KRAS, NRAS and BRAF hotspot mutations in plasma from patients with metastatic colorectal cancer (mCRC).

Integration of fully automated computer-aided pulmonary nodule detection into CT pulmonary angiography studies in the emergency department: effect on workflow and diagnostic accuracy.

To assess the feasibility of implementing fully automated computer-aided diagnosis (CAD) for detection of pulmonary nodules on CT pulmonary angiography (CTPA) studies in emergency setting.

Compensatory mechanisms for kyphotic change in the cervical spine according to alignment analysis of the cases after anterior cervical corpectomy and fusion.

Compensatory mechanisms for cervical kyphosis are unclear. Few alignment analyses targeted on ongoing cervical kyphosis and detailed each effect of compensatory alignment change.

The semi-automated algorithm for the detection of bone marrow oedema lesions in patients with axial spondyloarthritis.

The aim of the study was to create the efficient tool for semi-automated detection of bone marrow oedema lesions in patients with axial spondyloarthritis (axSpA). MRI examinations of 22 sacroiliac joints of patients with confirmed axSpA-related sacroiliitis (median SPARCC score: 14 points) were included into the study. Design of our algorithm is based on Maksymowych et al. evaluation method and consists of the following steps: manual segmentation of bones (T1W sequence), automated detection of reference sig...

A single molecule assay for ultrasensitive detection of Fn14 in human serum.

Fibroblast growth factor inducible-14 (Fn14) is a receptor protein that plays an important role in the progression of cancer and some other diseases. Here, an ultrasensitive assay was developed for the detection of Fn14 based on a digital sandwich enzyme-linked immunosorbent bead-based assay (dELISA). Beads containing a single immunocomplex are loaded into microwells (∼46 fL) and produce fluorescence through enzyme-catalyzed reactions in extremely small volumes. By measuring the number of fluorescent mi...

Monitoring of drinking water quality using automated ATP quantification.

A microfluidic based system was developed for automated online method for the rapid detection and monitoring of drinking water contamination utilising microbial Adrenosine-5'-Triphosphate (ATP) as a bacterial indicator. The system comprises a polymethyl methacrylate based microfluidic cartridge inserted into an enclosure incorporating the functions of fluid storage and delivery, lysis steps and real-time detection. Design, integration and operation of the resulting automated system are reported, including t...

Automated detection and localization system of myocardial infarction in single-beat ECG using Dual-Q TQWT and wavelet packet tensor decomposition.

It is challenging to conduct real-time identification of myocardial infarction (MI) due to artifact corruption and high dimensionality of multi-lead electrocardiogram (ECG). In the present study, we proposed an automated single-beat MI detection and localization system using dual-Q tunable Q-factor wavelet transformation (Dual-Q TQWT) denoising algorithm.

Automated buffer preparation using quaternary valve in fast performance liquid chromatography for protein purification from a cell membrane.

There is a great need for high-throughput protein purification to produce protein molecules for research and therapeutics. Although there have been significant advancements made in automated multi-step chromatography and preparative in-process design-of-experiment (DOE) capabilities in commercial fast performance liquid chromatography (FPLC) instruments, almost all commercial FPLCs rely on a binary buffer mixing system, which hinders automated buffer preparation. Nevertheless, current-generation FPLCs are e...

The impact of patient clinical information on automated skin cancer detection.

Skin cancer is one of the most common types of cancer worldwide. Over the past few years, different approaches have been proposed to deal with automated skin cancer detection. Nonetheless, most of them are based only on dermoscopic images and do not take into account the patient clinical information, an important clue towards clinical diagnosis. In this work, we present an approach to fill this gap. First, we introduce a new dataset composed of clinical images, collected using smartphones, and clinical data...

Integration of rolling circle amplification and optomagnetic detection on a polymer chip.

Rolling circle amplification (RCA) combined with padlock probe recognition of a DNA target is attractive for on-chip nucleic acid testing due to its high specificity and isothermal reaction conditions. However, the integration of RCA on an automated chip platform is challenging due to the different reagents needed for the reaction steps and the temperature sensitivity of the phi29 polymerase. Here, we describe the integration of an RCA assay on a single-use polymer chip platform where magnetic microbeads ar...

Precise 2D-patterned Incompatible Catalysts for Reactions in One-pot.

We show precise and direct two-dimensional (2D) printing of the incompatible polymer acid-base catalysts and their utility in one-pot two-step reactions. Multi-step catalytic reactions using incompatible catalysts in a one-pot reaction cascade require special methods and materials for isolation of catalysts from each other. This, in general is a tedious process requiring special polymer architectures as catalysts' carrier for preserving the activity of otherwise incompatible catalysts. We propose the immobi...

Skin surface detection in 3D optoacoustic mesoscopy based on dynamic programming.

Optoacoustic (photoacoustic) mesoscopy offers unique capabilities in skin imaging and resolves skin features associated with detection, diagnosis and management of disease. A critical first step in the quantitative analysis of clinical optoacoustic images is to identify the skin surface in a rapid, reliable and automated manner. Nevertheless, most common edge-and surface-detection algorithms cannot reliably detect the skin surface on 3D raster-scan optoacoustic mesoscopy (RSOM) images, due to discontinuitie...

Multidirectional Colonoscopy Quality Improvement Increases Adenoma Detection Rate: Results of the Seoul National University Hospital Healthcare System Gangnam Center Colonoscopy Quality Upgrade Project (Gangnam-CUP).

To prevent colorectal cancer, high-quality colonoscopy is advocated, undertaken by endoscopists with high adenoma detection rates (ADRs). Despite reports that various factors may impact ADRs, the significance of such factors is still unclear.


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