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PubMed Journals Articles About "BERNARD KRIEF SEARCH" RSS

10:23 EST 11th December 2017 | BioPortfolio

BERNARD KRIEF SEARCH PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest BERNARD KRIEF SEARCH articles that have been published worldwide.

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Showing "BERNARD KRIEF SEARCH" PubMed Articles 1–25 of 1,800+

Arnold Bernard Scheibel, M.D. (1923-2017).


Supporting inter-topic entity search for biomedical Linked Data based on heterogeneous relationships.

The keyword-based entity search restricts search space based on the preference of search. When given keywords and preferences are not related to the same biomedical topic, existing biomedical Linked Data search engines fail to deliver satisfactory results. This research aims to tackle this issue by supporting an inter-topic search-improving search with inputs, keywords and preferences, under different topics.

More than a memory: Confirmatory visual search is not caused by remembering a visual feature.

Previous research has demonstrated a preference for positive over negative information in visual search; asking whether a target object is green biases search towards green objects, even when this entails more perceptual processing than searching non-green objects. The present study investigated whether this confirmatory search bias is due to the presence of one particular (e.g., green) color in memory during search. Across two experiments, we show that this is not the critical factor in generating a confir...


Review of Peter L. Rosenbaum, Gabriel M. Ronen, Bernard Dan, Jennifer Johannensen, and Eric Racine, eds., Ethics in Child Health: Principles and Cases in Neurodisability.

The EBI search engine: EBI search as a service-making biological data accessible for all.

We present an update of the EBI Search engine, an easy-to-use fast text search and indexing system with powerful data navigation and retrieval capabilities. The interconnectivity that exists between data resources at EMBL-EBI provides easy, quick and precise navigation and a better understanding of the relationship between different data types that include nucleotide and protein sequences, genes, gene products, proteins, protein domains, protein families, enzymes and macromolecular structures, as well as th...

Short-term Internet search using makes people rely on search engines when facing unknown issues.

The Internet search engines, which have powerful search/sort functions and ease of use features, have become an indispensable tool for many individuals. The current study is to test whether the short-term Internet search training can make people more dependent on it. Thirty-one subjects out of forty subjects completed the search training study which included a pre-test, a six-day's training of Internet search, and a post-test. During the pre- and post- tests, subjects were asked to search online the answers...

One visual search, many memory searches: An eye-tracking investigation of hybrid search.

Suppose you go to the supermarket with a shopping list of 10 items held in memory. Your shopping expedition can be seen as a combination of visual search and memory search. This is known as "hybrid search." There is a growing interest in understanding how hybrid search tasks are accomplished. We used eye tracking to examine how manipulating the number of possible targets (the memory set size [MSS]) changes how observers (Os) search. We found that dwell time on each distractor increased with MSS, suggesting ...

How the nerves reached the muscle: Bernard Katz, Stephen W. Kuffler, and John C. Eccles-Certain implications of exile for the development of twentieth-century neurophysiology.

This article explores the work by Bernard Katz (1911-2003), Stephen W. Kuffler (1913-1980), and John C. Eccles (1903-1997) on the nerve-muscle junction as a milestone in twentieth-century neurophysiology with wider scientific implications. The historical question is approached from two perspectives: (a) an investigation of twentieth-century solutions to a longer physiological dispute and (b) an examination of a new kind of laboratory and academic cooperation. From this vantage point, the work pursued in Syd...

Anatomy and evolution of database search engines-a central component of mass spectrometry based proteomic workflows.

Sequence database search engines are bioinformatics algorithms that identify peptides from tandem mass spectra using a reference protein sequence database. Two decades of development, notably driven by advances in mass spectrometry, have provided scientists with more than 30 published search engines, each with its own properties. In this review, we present the common paradigm behind the different implementations, and its limitations for modern mass spectrometry datasets. We also detail how the search engine...

Contribution of physiologists to the identification of the humoral component of immunity in the 19(th) century.

The history of antimicrobial humoral immunity usually focuses on the works of the German school at the end of the 19(th) century, born in the tradition of chemistry and disinfection. Starting from an old quarrel of priority about serotherapy between Emil von Behring (1854-1917) and the French physiologists Charles Richet (1850-1935) and Jules Héricourt (1850-1938), we first confirm that the latter stated the principle of serotherapy in 1888 and put it into practice before the seminal Behring's article in 1...

One-Dimensional Search Dynamics of Tumor Suppressor p53 Regulated by a Disordered C-Terminal Domain.

Tumor suppressor p53 slides along DNA and finds its target sequence in drastically different and changing cellular conditions. To elucidate how p53 maintains efficient target search at different concentrations of divalent cations such as Ca(2+) and Mg(2+), we prepared two mutants of p53, each possessing one of its two DNA-binding domains, the CoreTet mutant having the structured core domain plus the tetramerization (Tet) domain, and the TetCT mutant having Tet plus the disordered C-terminal domain. We inves...

Low validity of Google Trends for behavioral forecasting of national suicide rates.

Recent research suggests that search volumes of the most popular search engine worldwide, Google, provided via Google Trends, could be associated with national suicide rates in the USA, UK, and some Asian countries. However, search volumes have mostly been studied in an ad hoc fashion, without controls for spurious associations. This study evaluated the validity and utility of Google Trends search volumes for behavioral forecasting of suicide rates in the USA, Germany, Austria, and Switzerland. Suicide-rela...

Search strategies in practice: Influence of information and task constraints.

The practice of a motor task has been conceptualized as a process of search through a perceptual-motor workspace. The present study investigated the influence of information and task constraints on the search strategy as reflected in the sequential relations of the outcome in a discrete movement virtual projectile task. The results showed that the relation between the changes of trial-to-trial movement outcome to performance level was dependent on the landscape of the task dynamics and the influence of inhe...

Combining local and global limitations of visual search.

There are different opinions about the roles of local interactions and central processing capacity in visual search. This study attempts to clarify the problem using a new version of relevant set cueing. A central precue indicates two symmetrical segments (that may contain a target object) within a circular array of objects presented briefly around the fixation point. The number of objects in the relevant segments, and density of objects in the array were varied independently. Three types of search experime...

Factors associated with postoperative complications in hydrocephalic infants diagnosed at Bernard Mevs Hospital in Port-au-Prince, Haiti from 2011 to 2013.

Complications worsen the prognosis of hydrocephalic children who undergo surgery. The main objective of this study was to determine factors associated with postoperative complications in Haitian hydrocephalic infants.

The topography of the environment alters the optimal search strategy for active particles.

In environments with scarce resources, adopting the right search strategy can make the difference between succeeding and failing, even between life and death. At different scales, this applies to molecular encounters in the cell cytoplasm, to animals looking for food or mates in natural landscapes, to rescuers during search and rescue operations in disaster zones, and to genetic computer algorithms exploring parameter spaces. When looking for sparse targets in a homogeneous environment, a combination of bal...

Formula: see text: Oblivious similarity based searching for encrypted data outsourced to an untrusted domain.

Public cloud storage services are becoming prevalent and myriad data sharing, archiving and collaborative services have emerged which harness the pay-as-you-go business model of public cloud. To ensure privacy and confidentiality often encrypted data is outsourced to such services, which further complicates the process of accessing relevant data by using search queries. Search over encrypted data schemes solve this problem by exploiting cryptographic primitives and secure indexing to identify outsourced dat...

A novel tool for the identification of correlations in medical data by faceted search.

This work focuses on the integration of multifaceted extensive data sets (e.g. laboratory values, vital data, medications) and partly unstructured medical data such as discharge letters, diagnostic reports, clinical notes etc. in a research database. Our main application is an integrated faceted search in nephrology based on information extraction results. We describe the details of the application of transplant medicine and the resulting technical architecture of the faceted search application.

The HMMER Web Server for Protein Sequence Similarity Search.

Protein sequence similarity search is one of the most commonly used bioinformatics methods for identifying evolutionarily related proteins. In general, sequences that are evolutionarily related share some degree of similarity, and sequence-search algorithms use this principle to identify homologs. The requirement for a fast and sensitive sequence search method led to the development of the HMMER software, which in the latest version (v3.1) uses a combination of sophisticated acceleration heuristics and math...

Optimal Length of Conformational Transition Region in Protein Search for Targets on DNA.

The starting point of many fundamental biological processes is associated with protein molecules finding and recognizing specific sites on DNA. However, despite a large number of experimental and theoretical studies on protein search for targets on DNA, many molecular aspects of underlying mechanisms are still not well understood. Experiments show that proteins bound to DNA can switch between slow recognition and fast search conformations. However, from a theoretical point of view, such conformational trans...

Understanding the Role of DNA Topology in Target Search Dynamics of Proteins.

A wide range of cellular processes initiates upon recognising and binding of proteins to specific DNA sites. Typically, the recognition process is incredibly fast owing to a complex mechanism that combines different 3D and 1D modes of translocation of the protein. While few studies performed on selected DNA topologies suggested that the DNA topology might alter the balance between these two modes and therefore the target search kinetics, its detail role in target search mechanism remains unclear. Here, we p...

Pre-stimulus pupil dilation and the preparatory control of attention.

Task preparation involves multiple component processes, including a general evaluative process that signals the need for adjustments in control, and the engagement of task-specific control settings. Here we examined the dynamics of these different mechanisms in preparing the attentional control system for visual search. We explored preparatory activity using pupil dilation, a well-established measure of task demands and effortful processing. In an initial exploratory experiment, participants were cued at th...

Distinct perceptual rhythms for feature and conjunction searches.

Feature and conjunction searches are widely used to study attentional deployment. However, the spatiotemporal behavior of attention integration in these tasks remains under debate. Are multiple search stimuli processed in parallel or sequentially? Does sampling of visual information and attentional deployment differ between these two types of search? If so, how? We used an innovative methodology to estimate the distribution of attention on a single-trial basis for feature and conjunction searches. Observers...

Comparing the effect of temporal delay on the availability of egocentric and allocentric information in visual search.

Frames of reference play a central role in perceiving an object's location and reaching to pick that object up. It is thought that the ventral stream, believed to subserve vision for perception, utilises allocentric coding, while the dorsal stream, argued to be responsible for vision for action, primarily uses an egocentric reference frame. We have previously shown that egocentric representations can survive a delay; however, it is possible that in comparison to allocentric information, egocentric informati...

Training Techniques for Visual Search in Complex Task Environments.

The goal for this study was to evaluate several visual search training techniques in an unmanned aerial vehicle (UAV) simulated task environment.


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