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PubMed Journals Articles About "BERNARD KRIEF SEARCH" RSS

20:28 EST 18th November 2018 | BioPortfolio

BERNARD KRIEF SEARCH PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest BERNARD KRIEF SEARCH articles that have been published worldwide.

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We have published hundreds of BERNARD KRIEF SEARCH news stories on BioPortfolio along with dozens of BERNARD KRIEF SEARCH Clinical Trials and PubMed Articles about BERNARD KRIEF SEARCH for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of BERNARD KRIEF SEARCH Companies in our database. You can also find out about relevant BERNARD KRIEF SEARCH Drugs and Medications on this site too.

Showing "BERNARD KRIEF SEARCH" PubMed Articles 1–25 of 1,900+

A point mutation in Phe71Ser in glycoprotein IX as a genetic cause of Bernard-Soulier syndrome: case report.

We need to be aware of rare causes of persistent thrombocytopenia as Bernard-Soulier syndrome (BSS). When BSS is suspected based on family history and giant platelets, genetic test for mutations of GPIbIXV is necessary. Management varies once you recognize the cause. Platelets transfusion and antifibrinolytics are the mainstay of therapy.


Revisiting the need for a literature search narrative: a brief methodological note.

'In this method note, we question if the primary search strategy in a systematic review should be accompanied by a search narrative. A search narrative could offer a conceptual and contextual report on the search strategy, which we suggest might benefit the peer review of literature searches and increase engagement with, and discussion of, the literature search strategy from review stakeholders, topic experts and lay users of research. Search narratives would also increase the transparency of decision-makin...

Considerations on the Taxonomy of the Genus Arhuaco Adams and Bernard 1977, and its Relationships with the Genus Pronophila Doubleday 1849 (Nymphalidae, Satyrinae).

Arhuaco Adams & Bernard (1977) is one of the least known genera of Neotropical Satyrinae. It comprises two species and presents an unusual disjunct distribution, with A. ica Adams & Bernard (1977), endemic to the isolated Colombian Sierra Nevada de Santa Marta, and A. dryadina (Schaus 1913) found in the mountains of Costa Rica and Panama. Here, the female of A. dryadina is described, and a new generic diagnosis is presented. Affinities with other genera of the subtribe Pronophilina, in particular the potent...


In Memoriam: Bernard J. Carroll, MD, PhD.

Systematic literature search in PubMed : A short introduction.

In order to identify current (and relevant) evidence for a specific clinical question within the unmanageable amount of information available, solid skills in performing a systematic literature search are essential. An efficient approach is to search a biomedical database containing relevant literature citations of study reports. In this article, we explain step by step how to perform a systematic literature search via PubMed (MEDLINE) by means of an example research question in the field of ophthalmolo...

Design and implementation of a tool for conversion of search strategies between PubMed and Ovid MEDLINE.

Both PubMed and Ovid MEDLINE contain records from the MEDLINE database. However, there are subtle differences in content, functionality, and search syntax between the two. There are many instances in which researchers may wish to search both interfaces, such as when conducting supplementary searching for a systematic review to retrieve unique content from PubMed or when using a previously published search strategy from a different interface, but little guidance on how to best conduct these searches. The aim...

A novel germline mutation in GP1BA gene N-terminal domain in monoallelic Bernard-Soulier syndrome.

Mutations in the GP1BA gene have been associated with platelet-type von Willebrand disease and Bernard-Soulier syndrome. Here, we report a novel GP1BA mutation in a family with autosomal dominant macrothrombocytopenia and mild bleeding. We performed analyses of seven family members. Using whole-exome sequencing of germline DNA samples, we identified a heterozygous single-nucleotide change in GP1BA (exone2:c.176T>G), encoding a p.Leu59Arg substitution in the N-terminal domain, segregating with macrothrombocy...

A general model of forager search: Adaptive encounter-conditional heuristics outperform Lévy flights in the search for patchily distributed prey.

A theoretical and applied literature has suggested that foragers search using Lévy flights, since Lévy flights can maximize the efficiency of search in the absence of information on the location of randomly distributed prey. Foragers, however, often have available to them at least some information about the distribution of prey, gained either through evolved mechanisms, experience and memory, or social transmission of information. As such, we might expect selection for heuristics that make use of such inf...

The effects of array structure and secondary cognitive task demand on processes of visual search.

Many aspects of our everyday behaviour require that we search for objects. However, in real situations search is often conducted while internal and external factors compete for our attention resources. Cognitive distraction interferes with our ability to search for targets, increasing search times. Here we consider whether effects of cognitive distraction interfere differentially with three distinct phases of search: initiating search, overtly scanning through items in the display, and verifying that the ob...

Negative cues lead to more inefficient search than positive cues even at later stages of visual search.

Observers can focus their attention on task-relevant items in visual search when they have prior knowledge about the target's properties (i.e., positive cues). However, little is known about how negative cues, which specify the features of task-irrelevant items, can be used to guide attention away from distractors and how their effects differ from those of positive cues. It has been proposed that when a distractor color is cued, people would first select the to-be-ignored items early in search and then inhi...

Occluded information is restored at preview but not during visual search.

Objects often appear with some amount of occlusion. We fill in missing information using local shape features even before attending to those objects-a process called amodal completion. Here we explore the possibility that knowledge about common realistic objects can be used to "restore" missing information even in cases where amodal completion is not expected. We systematically varied whether visual search targets were occluded or not, both at preview and in search displays. Button-press responses were long...

Improving the quality of systematic reviews of neurological conditions: an assessment of current practice and the development and validation of six new search strategies.

Our aim was to study the quality of the literature search strategies used in recent systematic reviews, and to develop and assess the diagnostic accuracy of six new search strategies (i.e. hedges).

Applicability of internet search index for asthma admission forecast using machine learning.

This study aimed to determine whether a search index could provide insight into trends in asthma admission in China. An Internet search index is a powerful tool to monitor and predict epidemic outbreaks. However, whether using an internet search index can significantly improve asthma admissions forecasts remains unknown. The long-term goal is to develop a surveillance system to help early detection and interventions for asthma and to avoid asthma health care resource shortages in advance.

Electrophysiological correlates of active suppression and attentional selection in preview visual search.

Advance preview of a subset of distractor objects improves the efficiency of visual search performance, but the causes and mechanisms of such preview benefits remain unclear. Here, we employed event-related potential (ERP) markers of the selective processing of preview displays and full search displays in lateralised preview search tasks where only one side of the search displays was task-relevant. Preview displays elicited a sustained positivity contralateral to the relevant side (P component), indicative ...

ToBio: Global Pathway Similarity Search based on Topological and Biological Features.

Pathway similarity search plays a vital role in the post-genomics era. Unfortunately, pathway similarity search involves the graph isomorphism problem which is NP-complete. Therefore, efficient search algorithms are desirable. In this work, we propose a novel global pathway similarity search approach named ToBio, which considers both topological and biological features for effective global pathway similarity search. Specifically, as motivated from nature, various topological and biological features includin...

Alloimmunization in Congenital Deficiencies of Platelet Surface Glycoproteins: Focus on Glanzmann's Thrombasthenia and Bernard-Soulier's Syndrome.

Glanzmann's thrombasthenia (GT) and Bernard-Soulier's syndrome (BSS) are well-understood congenital bleeding disorders, showing defect/deficiency of platelet glycoprotein (GP) IIb/IIIa (integrin αIIbβ3) and GPIb-IX-V complexes respectively, with relevant clinical, laboratory, biochemical, and genetic features. Following platelet transfusion, affected patients may develop antiplatelet antibodies (to human leukocyte antigen [HLA], and/or αIIbβ3 in GT or GPIb-IX in BSS), which may render future platelet tr...

mTM-align: a server for fast protein structure database search and multiple protein structure alignment.

With the rapid increase of the number of protein structures in the Protein Data Bank, it becomes urgent to develop algorithms for efficient protein structure comparisons. In this article, we present the mTM-align server, which consists of two closely related modules: one for structure database search and the other for multiple structure alignment. The database search is speeded up based on a heuristic algorithm and a hierarchical organization of the structures in the database. The multiple structure alignme...

Computational Feasibility of an Exhaustive Search of Side-Chain Conformations in Protein-Protein Docking.

Protein-protein docking procedures typically perform the global scan of the proteins relative positions, followed by the local refinement of the putative matches. Because of the size of the search space, the global scan is usually implemented as rigid-body search, using computationally inexpensive intermolecular energy approximations. An adequate refinement has to take into account structural flexibility. Since the refinement performs conformational search of the interacting proteins, it is extremely comput...

Using Search Engine Data as a Tool to Predict Syphilis.

Researchers have suggested that social media and online search data might be used to monitor and predict syphilis and other sexually transmitted diseases. Because people at risk for syphilis might seek sexual health and risk-related information on the internet, we investigated associations between internet state-level search query data (e.g., Google Trends) and reported weekly syphilis cases.

Using Google Trends to assess global public interest in osteoarthritis.

To evaluate global public interest in osteoarthritis by assessing changes in Internet search popularity of the disease over a 10-year period. Google Trends was used to obtain search popularity scores for the word "osteoarthritis" (OA) between January 2004 and June 2018. We also analyzed changes in search volume relative to changes in search patterns for all health topics. Search interest in OA was high relative to all other health searches over the given timeframe. Overall, searches for OA steadily decrease...

How Does the World Google the Internet, Anxiety, and Happiness?

This article investigates how the world uses Google, the most popular search engine, to look for information about the "Internet" as well as two symptoms of emotional well-being, namely "anxiety" and "happiness." Data corresponding to 202 countries were collected for a period of 5 years from 2013 to 2017 using Google Trends, a free surveillance tool that reports data from the search engine. The search volume of "Internet" was positively correlated with that of "anxiety" as well as "happiness." Furthermore, ...

The Radiologist's Gaze: Mapping Three-Dimensional Visual Search in Computed Tomography of the Abdomen and Pelvis.

A radiologist's search pattern can directly influence patient management. A missed finding is a missed opportunity for intervention. Multiple studies have attempted to describe and quantify search patterns but have mainly focused on chest radiographs and chest CTs. Here, we describe and quantify the visual search patterns of 17 radiologists as they scroll through 6 CTs of the abdomen and pelvis. Search pattern tracings varied among individuals and remained relatively consistent per individual between cases....

Correction: Transcranial direct current stimulation (tDCS) facilitates overall visual search response times but does not interact with visual search task factors.

[This corrects the article DOI: 10.1371/journal.pone.0194640.].

Visual search accelerates during adolescence.

We studied changes in visual-search performance and behavior during adolescence. Search performance was analyzed in terms of reaction time and response accuracy. Search behavior was analyzed in terms of the objects fixated and the duration of these fixations. A large group of adolescents (N = 140; age: 12-19 years; 47% female, 53% male) participated in a visual-search experiment in which their eye movements were recorded with an eye tracker. The experiment consisted of 144 trials (50% with a target present)...

Spatial correlation between localized decreases in exploratory visual search performance and areas of glaucomatous visual field loss.

Visual search is a critical skill for several daily tasks and may be compromised in patients with impaired vision. The objective of this study was to study the relationships between exploratory visual search performance (EVSP) visual field (VF) sensitivity in patients with glaucoma.


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