Advertisement

Topics

PubMed Journals Articles About "Evaluating Cellularity Structural Connectivity Whole Brain Slides Using" RSS

13:17 EDT 23rd March 2019 | BioPortfolio

Evaluating Cellularity Structural Connectivity Whole Brain Slides Using PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Evaluating Cellularity Structural Connectivity Whole Brain Slides Using articles that have been published worldwide.

More Information about "Evaluating Cellularity Structural Connectivity Whole Brain Slides Using" on BioPortfolio

We have published hundreds of Evaluating Cellularity Structural Connectivity Whole Brain Slides Using news stories on BioPortfolio along with dozens of Evaluating Cellularity Structural Connectivity Whole Brain Slides Using Clinical Trials and PubMed Articles about Evaluating Cellularity Structural Connectivity Whole Brain Slides Using for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Evaluating Cellularity Structural Connectivity Whole Brain Slides Using Companies in our database. You can also find out about relevant Evaluating Cellularity Structural Connectivity Whole Brain Slides Using Drugs and Medications on this site too.

Showing "Evaluating cellularity structural connectivity whole brain slides using" PubMed Articles 1–25 of 16,000+

Evaluating cellularity and structural connectivity on whole brain slides using a custom-made digital pathology pipeline.

In brain research, the histopathological examination of coronar whole-brain slides provides important insights into spatial disease characteristics. Regarding brain tumor research, this enables visualization of tumor heterogeneity, infiltration patterns and the relationship with the surrounding brain parenchyma. The precise correlation between radiological imaging and post-mortem brains is of special interest.


Quantification of structural brain connectivity via a conductance model.

Connectomics has proved promising in quantifying and understanding the effects of development, aging and an array of diseases on the brain. In this work, we propose a new structural connectivity measure from diffusion MRI that allows us to incorporate direct brain connections, as well as indirect ones that would not be otherwise accounted for by standard techniques and that may be key for the better understanding of function from structure. From our experiments on the Human Connectome Project dataset, we fi...

Connectome-wide network analysis of white matter connectivity in Alzheimer's disease.

A multivariate analytical strategy may pinpoint the structural connectivity patterns associated with Alzheimer's disease (AD) pathology in connectome-wide association studies. Diffusion magnetic resonance imaging data from 161 participants including subjects with healthy controls, AD, stable and converting mild cognitive impairment, were selected for group-wise comparisons. A multivariate distance matrix regression (MDMR) analysis was performed to detect abnormality in brain structural network along with di...


Reproducibility and intercorrelation of graph theoretical measures in structural brain connectivity networks.

Diffusion-weighted magnetic resonance imaging can be used to non-invasively probe the brain microstructure. In addition, recent advances have enabled the identification of complex fiber configurations present in most of the white matter. This has improved the investigation of structural connectivity with tractography methods. Whole-brain structural connectivity networks, or connectomes, are reconstructed by parcellating the gray matter and performing tractography to determine connectivity between these regi...

Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study.

Higher polygenic risk score for schizophrenia (szPGRS) has been associated with lower cognitive function and might be a predictor of decline in brain structure in apparently healthy populations. Age-related declines in structural brain connectivity-measured using white matter diffusion MRI -are evident from cross-sectional data. Yet, it remains unclear how graph theoretical metrics of the structural connectome change over time, and whether szPGRS is associated with differences in ageing-related changes in h...

Correction to: Functional Connectivity in Adult Brain Tumor Patients: A Systematic Review, by Fox ME and King TZ. Brain Connect 2018;8(7):381-397. DOI: 10.1089/brain.2018.0623.

A connectome-based mechanistic model of focal cortical dysplasia.

Neuroimaging studies have consistently shown distributed brain anomalies in epilepsy syndromes associated with a focal structural lesion, particularly mesiotemporal sclerosis. Conversely, a system-level approach to focal cortical dysplasia has been rarely considered, likely due to methodological difficulties in addressing variable location and topography. Given the known heterogeneity in focal cortical dysplasia histopathology, we hypothesized that lesional connectivity consists of subtypes with distinct st...

Patterns of functional connectivity in an aging population: The Rotterdam Study.

Structural brain markers are studied extensively in the field of neurodegeneration, but are thought to occur rather late in the process. Functional measures such as functional connectivity are gaining interest as potentially more subtle markers of neurodegeneration. However, brain structure and function are also affected by 'normal' brain ageing. More information is needed on how functional connectivity relates to aging, particularly in the absence of overt neurodegenerative disease. We investigated the ass...

Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity.

Women experience greater difficulty quitting smoking than men, which may be explained by sex differences in brain circuitry underlying cognitive control. Prior work has linked reduced interhemispheric executive control network (ECN) coupling with poor executive function, shorter time to relapse, and greater substance use. Lower structural connectivity between a key ECN hub, the dorsolateral prefrontal cortex (DLPFC), and the dorsal striatum (DS) also contributes to less efficient cognitive control recruitme...

Copula directional dependence for inference and statistical analysis of whole-brain connectivity from fMRI data.

Inferring connectivity between brain regions has been raising a lot of attention in recent decades. Copula directional dependence (CDD) is a statistical measure of directed connectivity, which does not require strict assumptions on probability distributions and linearity.

Data-driven brain network models differentiate variability across language tasks.

The relationship between brain structure and function has been probed using a variety of approaches, but how the underlying structural connectivity of the human brain drives behavior is far from understood. To investigate the effect of anatomical brain organization on human task performance, we use a data-driven computational modeling approach and explore the functional effects of naturally occurring structural differences in brain networks. We construct personalized brain network models by combining anatom...

Interactions between gut permeability and brain structure and function in health and irritable bowel syndrome.

Changes in brain-gut interactions have been implicated in the pathophysiology of chronic visceral pain in irritable bowel syndrome (IBS). Different mechanisms of sensitization of visceral afferent pathways may contribute to the chronic visceral pain reports and associated brain changes that characterize IBS. They include increased gut permeability and gut associated immune system activation, and an imbalance in descending pain inhibitory and facilitatory mechanisms. In order to study the involvement of thes...

Alterations of the brain network in idiopathic rapid eye movement sleep behavior disorder: structural connectivity analysis.

To evaluate and compare structural connectivity using graph theoretical analysis in patients with idiopathic rapid eye movement sleep behavior disorder (iRBD) and healthy subjects.

Neuron density fundamentally relates to architecture and connectivity of the primate cerebral cortex.

Studies of structural brain connectivity have revealed many intriguing features of complex cortical networks. To advance integrative theories of cortical organization, an understanding is required of how connectivity interrelates with other aspects of brain structure. Recent studies have suggested that interareal connectivity may be related to a variety of macroscopic as well as microscopic architectonic features of cortical areas. However, it is unclear how these features are inter-dependent and which of t...

Early breast milk exposure modifies brain connectivity in preterm infants.

Preterm infants are at increased risk of alterations in brain structure and connectivity, and subsequent neurocognitive impairment. Breast milk may be more advantageous than formula feed for promoting brain development in infants born at term, but uncertainties remain about its effect on preterm brain development and the optimal nutritional regimen for preterm infants. We test the hypothesis that breast milk exposure is associated with improved markers of brain development and connectivity in preterm infant...

Intrinsic functional and structural connectivity of emotion regulation networks in obsessive-compulsive disorder.

Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the dispositional use of emotion regulation strategies and with OCD severity. OCD patients (n = 73) and HCs (n = 42) were assessed for suppression and reappraisal strategies using the Emotion Reg...

Multimodal neuroimaging study reveals dissociable processes between structural and functional networks in patients with subacute intracerebral hemorrhage.

Emerging evidence has revealed widespread stroke-induced brain dysconnectivity, which leads to abnormal network organization. However, there are apparent discrepancies in dysconnectivity between structural connectivity and functional connectivity studies. In this work, resting-state fMRI and structural diffusion tensor imaging were obtained from 26 patients with subacute (10-14 days) intracerebral hemorrhage (ICH) and 20 matched healthy participants (patients/controls = 21/18 after head motion rejection). ...

Alterations in Intra- and Interregional Intrinsic Brain Connectivity Are Differentially Associated with Memory Performance in Amnestic Mild Cognitive Impairment.

Previous research has separated spatial patterns of intra- and interregional intrinsic brain connectivity, as evaluated by regional homogeneity (ReHo) and functional connectivity (FC), respectively, in prodromal Alzheimer's disease (AD). Moreover, the intra- and interregional intrinsic brain connectivities have been demonstrated to have a significant relationship with each other.

Comparison of fluctuations in global network topology of modeled and empirical brain functional connectivity.

Dynamic models of large-scale brain activity have been used for reproducing many empirical findings on human brain functional connectivity. Features that have been shown to be reproducible by comparing modeled to empirical data include functional connectivity measured over several minutes of resting-state functional magnetic resonance imaging, as well as its time-resolved fluctuations on a time scale of tens of seconds. However, comparison of modeled and empirical data has not been conducted yet for fluctua...

Dynamics of brain connectivity after stroke.

Recovery from a stroke is a dynamic time-dependent process, in which the central nervous system reorganises to accommodate for the impact of the injury. The purpose of this paper is to review recent longitudinal studies of changes in brain connectivity after stroke. A systematic review of research papers reporting functional or effective connectivity at two or more time points in stroke patients was conducted. Stroke leads to an early reduction of connectivity in the motor network. With recovery time, the c...

Altered structural and functional brain network overall organization predict human intertemporal decision-making.

Intertemporal decision-making is naturally ubiquitous to us: individuals always make a decision with different consequences occurring at different moments. These choices are invariably involved in life-changing outcomes regarding marriage, education, fertility, long-term well-being, and even public policy. Previous studies have clearly uncovered the neurobiological mechanism of the intertemporal decision in the schemes of regional location or sub-network. However, it still remains unclear how to characteriz...

Connectomic imaging reveals Huntington-related pathological and pharmaceutical effects in a mouse model.

Recent studies suggest that neurodegenerative diseases could affect brain structure and function in disease-specific network patterns; however, how spontaneous activity affects structural covariance network (SC) is not clear. We hypothesized that hyper-excitability in Huntington disease (HD) disrupts the coordinated structural and functional connectivity, and treatment with memantine helps to reduce excitotoxicity and normalize the connectivity. MRI was conducted to measure somatosensory activation, resting...

Abnormal cerebellum-DMN regions connectivity in unmedicated bipolar II disorder.

Bipolar disorder (BD) is a common psychiatric disease. Previous studies have found abnormalities in structural and functional brain connectivity in BD patients. However, few studies have focused on the functional connectivity (FC) of the cerebellum and its sub-regions in patients with BD. The present study aimed to examine the FC of cerebellum-default mode network (DMN) regions in patients with BD II.

Frequency-specific age-related decreased brain network diversity in cognitively healthy elderly: A whole-brain data-driven analysis.

Age-related changes in functional brain network have been well documented. However, recent studies have suggested the nonstationary properties of the functional connectivity of the brain, and little is known about the changes of functional connectivity dynamics during aging. In this study, a two-step singular value decomposition was introduced to capture the dynamic patterns of the time-varying functional connectivity in different frequency intervals, and the whole-brain and regional brain diversity were qu...

Traces of Statistical Learning in the Brain's Functional Connectivity after Artificial Language Exposure.

Our environment is full of statistical regularities, and we are attuned to learn about these regularities by employing Statistical Learning (SL), a domain-general ability that enables the implicit detection of probabilistic regularities in our surrounding environment. The role of brain connectivity on SL has been previously explored, highlighting the relevance of structural and functional connections between frontal, parietal, and temporal cortices. However, whether SL can induce changes in the functional c...


Advertisement
Quick Search
Advertisement
Advertisement