PubMed Journals Articles About "Fluorous Technologies" RSS

17:06 EDT 18th March 2018 | BioPortfolio

Fluorous Technologies PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Fluorous Technologies articles that have been published worldwide.

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Showing "Fluorous Technologies" PubMed Articles 1–25 of 2,000+

Fluorous-assisted metal chelate affinity extraction for nucleotides followed by HILIC-MS/MS analysis.

We herein developed a selective method for the determination of nucleotides by fluorous-assisted metal chelate affinity extraction followed by hydrophilic interaction liquid chromatography (HILIC) combined with tandem mass spectrometric (MS/MS) analysis. In this study, the nucleotides were selectively chelated by Fe(III)-immobilized perfluoroalkyliminodiacetic acid, and the resulting chelates were subsequently extracted into a fluorous solvent. The nucleotides present in the fluorous solvent were then back-...

Multicompartment Theranostic Nanoemulsions Stabilized by a Triphilic Semifluorinated Block Copolymer.

The presence of a perfluorocarbon block in an amphiphilic polymer has been shown to be an additional driving force towards nanoparticle assembly. In the preparation of nanoemulsions, this perfluorocarbon block also provides enhanced particle stability. Herein, the synthesis of a new triphilic, semifluorinated amphiphile, M2F8H18, is introduced. This ABC type block copolymer can be used to formulate extremely stable nanoemulsions, assembled around a lipophilic droplet, with lifetimes of one year or more. The...

pH Responsive Doxorubicin Delivery by Fluorous Polymers for Cancer Treatment.

Polymeric nanoparticles have emerged as valuable drug delivery vehicles as they improve solubility of hydrophobic drugs, enhance circulation lifetime, and can improve the biodistribution profile of small-molecule therapeutics. These nanoparticles can take on a host of polymer architectures including polymersomes, hyperbranched nanoparticles, and dendrimers. We have recently reported that simple low molecular weight fluorous copolymers can self-assemble into nanoparticles and show exceptional passive targeti...

Impact of Long Range Electronic Effect of Fluorous Ponytail on Metal Coordination during Solvent Extraction.

With the need for a precise description of the long range electronic effects of a perfloroalkyl chain (F-ponytail) grafted on metal chelators, we studied in detail the effect of a spacer inserted between the polar complexing head and the F-ponytail, in relation with the metal coordination ability of the resulting molecules. The prepared molecules were then employed for the extraction of various metals from an aqueous phase into an organic phase, and the optimum spacer length could be estimate between three ...

Health technology assessments conducted in health care facilities: A strategic practice? Findings from a content analysis of HTA reports.

In this paper, we test the hypothesis that health technology assessment units located in hospitals tend to be more optimistic toward technologies that are currently in use in their organization than technologies that are not. The data include 108 health technologies assessed in 87 full-scale health technology assessment reports produced by the four main local health technology assessment units in Quebec (Canada) on behalf of decision makers from the same facility. We found that 58 (53.7 percent) of the 108 ...

Three-dimensional Technologies in Orthopedics.

New 3-dimensional digital technologies are revolutionizing orthopedic clinical practice, allowing structures of any complexity to be manufactured in just hours. Such technologies can make surgery for complex cases more precise, more cost-effective, and possibly easier to perform. Applications include pre-operative planning, surgical simulation, patient-specific instrumentation and implants, bioprinting, prosthetics, and orthotics. The basic principles of 3- dimensional technologies, including imaging, desig...

A brief review of single-cell transcriptomic technologies.

In recent years, there has been an effort to develop new technologies for measuring gene expression and sequence information from thousands of individual cells. Large data sets that were obtained using these 'single cell' technologies have allowed scientists to address fundamental questions in biomedicine ranging from stems cells and development to cancer and immunology. Here, we provide a brief review of recent developments in single-cell technology. Our intention is to provide a quick background for newco...

On the Cusp of a Healthcare Revolution: BME Technologies Have the Potential to ?Transform Our World?

Of the key technologies listed as "ready to propel industries and transform our world" in the 2017 report Top 50 Emerging Technologies: Growth Opportunities of Strategic Imperative, most fall under the scope of biomedical engineering (BME). Issued by the major market research and analysis company Frost and Sullivan [1], the report's findings are no surprise to the researchers, clinicians, and others who are heavily invested in this field.

The state of knowledge on technologies and their use for fall detection: A scoping review.

Globally, populations are aging with increasing life spans. The normal aging process and the resulting disabilities increase fall risks. Falls are an important cause of injury, loss of independence and institutionalization. Technologies have been developed to detect falls and reduce their consequences but their use and impact on quality of life remain debatable. Reviews on fall detection technologies exist but are not extensive. A comprehensive literature review on the state of knowledge of fall detection t...

3D Metal Printing - Additive Manufacturing Technologies for Frameworks of Implant-Borne Fixed Dental Prosthesis.

An edentulous patient was rehabilitated with maxillary metal-ceramic and mandibular metal-resin implant-supported fixed dental prosthesis (FDP). Metal frameworks of the FDPs were fabricated using 3D additive manufacturing technologies utilizing selective laser melting (SLM) and electron beam melting (EBM) processes. Both SLM and EBM technologies were employed in combination with computer numerical control (CNC) post-machining at the implant interface. This report highlights the technical and clinical protoc...

Patent Protection for Microbial Technologies.

Microbial technologies often serve as the basis of fundamental research tools in molecular biology. These present a variety of ethical, legal and social issues concerning their patenting. This commentary presents several case studies of these issues across three major microbiological tools: CRISPR, viral vectors, and antimicrobial resistance drugs. It concludes that the development of these technologies-both scientifically and commercially-depend, in part, on the patent regime available for each, and resear...

Society of Biomolecular Imaging and Informatics High-Content Screening/High-Content Analysis Emerging Technologies in Biological Models, When and Why?

Current applications and new opportunities for the thermal and non-thermal processing technologies to generate berry product or extracts with high nutraceutical contents.

The demand from consumer for safe and nutritious berry and berry products has promoted the rapid development of non-conventional processing technologies. This review summarizes the recent advances of thermal and non-thermal processing technologies in berry and berry products, including microwave, ohmic heating, high pressure processing, irradiation, dense phase carbon dioxide, ultrasonic processing, pulsed electric field, ozone, membrane processing technologies, cold plasma, and hydrothermodynamic cavitatio...

Enabling technologies in synthetic biology--DNA synthesis, assembly and editing.

Synthetic biology is an emerging discipline, which aims at creating artificial lives or remolding the present organisms to generate new features. To achieve these goals, synthetic biologists need to design and synthesize new genes, pathways, modules or even whole genomes. As these enabling technologies (e.g. gene synthesis, DNA assembly and genome editing) are very important for the progress of synthetic biology, we will focus on the development of these technologies in this review.

Life Cycle Environmental Impacts of Disinfection Technologies Used in Small Drinking Water Systems.

Small drinking water systems serve a fifth of the U.S. population and rely heavily on disinfection. While chlorine disinfection is common, there is interest in minimizing chemical addition, especially due to carcinogenic disinfection byproducts and chlorine-resistant pathogens, by using ultraviolet technologies; however, the relative, broader environmental impacts of these technologies are not well established, especially in the context of small (

Everyday technology use among older deaf adults.

Technology holds great potential to support Deaf individuals as they age into older adulthood. However, it is unclear to what extent Deaf seniors are using technology in everyday life or whether they experience challenges in using technology. The current study explored technology use among older Deaf adults with regard to attitudes, adoption style, and frequency of use for a wide range of technologies, including assistive technologies (ATs) for persons with hearing loss and general, everyday technologies.

Interprofessional Education in Allied Health Using Virtual Technologies.

Interprofessional education (IPE) is becoming increasingly prevalent in health science education, with the goal of preparing students to work collaboratively in teams within the healthcare environment. Students in our cytotechnology and radiation therapy (RT) programs used virtual technologies to demonstrate their professions using case studies. The purpose of this activity was to see if our students' knowledge of each other's professions and educational technologies increased and if the students had a bett...

Ethylene control technologies in extending post-harvest shelf life of climacteric fruit.

Fresh fruit is important for a healthy diet. However, due to their seasonal production, regional specific cultivation and perishable nature, it is essential to develop preservation technologies to extend the post-harvest shelf life of fresh fruits. Climacteric fruit adopt spoilage because of ethylene, a key hormone associated with the ripening process. Therefore, controlling ethylene activity by following safe and effective approaches is a key to extend the post-harvest shelf life of fruit. In this review, ...

Computer technologies to integrate medical treatments to manage multimorbidity.

The high prevalence of multimorbid cases is a challenge for Health-Care Systems today. Clinical practice guidelines are the means to register and transmit the available evidence-based medical knowledge concerning concrete diseases. Several computer languages have been defined to represent this knowledge in a way that computers could use to help physicians in the daily practice of medicine. The generation of guidelines for all possible multimorbidities entails several issues that are difficult to address. Co...

Health Information Technology Usability Evaluation Scale (Health-ITUES) for Usability Assessment of Mobile Health Technology: Validation Study.

Mobile technology has become a ubiquitous technology and can be particularly useful in the delivery of health interventions. This technology can allow us to deliver interventions to scale, cover broad geographic areas, and deliver technologies in highly tailored ways based on the preferences or characteristics of users. The broad use of mobile technologies supports the need for usability assessments of these tools. Although there have been a number of usability assessment instruments developed, none have be...

Blockchain distributed ledger technologies for biomedical and health care applications.

To introduce blockchain technologies, including their benefits, pitfalls, and the latest applications, to the biomedical and health care domains.

Review on characteristics of PAHs in atmosphere, anthropogenic sources and control technologies.

Polycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds composed of multiple aromatic rings. PAHs are ubiquitous atmospheric pollutants which are well-recognized as carcinogenic, teratogenic and genotoxic compounds. PAHs are released from incomplete combustion or pyrolysis of materials containing carbon and hydrogen, such as coal, oil, wood and petroleum products. Understanding the characteristics of PAHs in atmosphere, source profiles and technologies available for controlling PAHs emissio...

Technology selection for ballast water treatment by multi-stakeholders: A multi-attribute decision analysis approach based on the combined weights and extension theory.

This objective of this study is to develop a generic multi-attribute decision analysis framework for ranking the technologies for ballast water treatment and determine their grades. An evaluation criteria system consisting of eight criteria in four categories was used to evaluate the technologies for ballast water treatment. The Best-Worst method, which is a subjective weighting method and Criteria importance through inter-criteria correlation method, which is an objective weighting method, were combined to...

Metabolomics for improving pregnancy outcomes in women undergoing assisted reproductive technologies.

In order to overcome the low effectiveness of assisted reproductive technologies (ART) and the high incidence of multiple births, metabolomics is proposed as a non-invasive method to assess oocyte quality, embryo viability, and endometrial receptivity, and facilitate a targeted subfertility treatment.

Conditional Degrons for Controlling Protein Expression at the Protein Level.

The conditional depletion of a protein of interest (POI) is useful not only for loss-of-function studies, but also for the modulation of biological pathways. Technologies that work at the level of DNA, mRNA, and protein are available for temporal protein depletion. Compared with technologies targeting the pretranslation steps, direct protein depletion (or protein knockdown approaches) is advantageous in terms of specificity, reversibility, and time required for depletion, which can be achieved by fusing a P...

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