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PubMed Journals Articles About "Inform Diagnostics" RSS

02:00 EDT 24th May 2018 | BioPortfolio

Inform Diagnostics PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Inform Diagnostics articles that have been published worldwide.

More Information about "Inform Diagnostics" on BioPortfolio

We have published hundreds of Inform Diagnostics news stories on BioPortfolio along with dozens of Inform Diagnostics Clinical Trials and PubMed Articles about Inform Diagnostics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Inform Diagnostics Companies in our database. You can also find out about relevant Inform Diagnostics Drugs and Medications on this site too.

Showing "Inform Diagnostics" PubMed Articles 1–25 of 1,700+

Big Potential from Small Agents: Nanoparticles for Imaging-Based Companion Diagnostics.

The importance of medical imaging in the diagnosis and monitoring of cancer cannot be overstated. As personalized cancer treatments are gaining popularity, a need for more advanced imaging techniques has grown significantly. Nanoparticles are uniquely suited to fill this void, not only as imaging contrast agents but also as companion diagnostics. This manuscript provides an overview of many ways nanoparticle imaging agents have contributed to cancer imaging, both preclinically and in the clinic, as well as ...


A PEG-based method for the isolation of urinary exosomes and its application in renal fibrosis diagnostics using cargo miR-29c and miR-21 analysis.

To assess a new and highly specific, but low-cost, easily performed and suitable for large-scale applications method for renal fibrosis (RF) diagnostics.

Nucleic acid diagnostic approaches in parasitology.

Nucleic acid diagnostic technologies are partly replacing traditional microscopy and antigen detection methods in parasitological diagnostics. In particular, the diagnostics of parasitic diarrhea is undergoing a transformation due to the application of polymerase chain reaction (PCR) tests. Diagnostics of malaria is still based on microscopy, but rapid nucleic acid tests are emerging. Laboratories of clinical microbiology in Finland currently provide PCR tests e.g. for intestinal protozoa, Toxoplasma and Tr...


Is bronchoscopy always justified in diagnosis of haemoptysis?

Fiber-optic bronchoscopy (FOB) is commonly performed in the first line in diagnostic process of haemoptysis. However, lots of evidences suggest that in haemoptysis FOB do not always provide additional, useful information to radiological diagnostics. Therefore, this study aimed to evaluate the validity of performing FOB as a method of choice in first line diagnostics of haemoptysis.

Comparative evaluation of neonatal bilirubin using radiometer whole blood co-oximetry and plasma bilirubin methods from Roche diagnostics and Ortho clinical diagnostics.

Clinically significant variation has been reported within and between plasma and whole blood total bilirubin methods used to identify neonates for whom clinical intervention for hyperbilirubinemia may be required.

SWISS SYMPOSIUM in Point-of-Care Diagnostics at HES-SO Valais.

When an innovative technology is going to be implemented in hospitals, medical practices or pharmacies, it often does not appear really new to researchers. It is the implementation itself and the domain where it is used that are at the core of innovation. That's why the SWISS SYMPOSIUM in Point-of-Care Diagnostics (POCD) brings together key stakeholders from research and industry to clinical settings and patient care to exchange knowledge and experience and to stimulate activities in POCD.

Expanding Existing Antimicrobial Stewardship Programs in Pediatrics: What Comes Next.

The prevalence of pediatric antimicrobial stewardship programs (ASPs) is increasing in acute care facilities across the United States. Over the past several years, the evidence base used to inform effective stewardship practices has expanded, and regulatory interest in stewardship programs has increased. Here, we review approaches for established, hospital-based pediatric ASPs to adapt and report standardized metrics, broaden their reach to specialized populations, expand to undertake novel stewardship init...

Reference materials for molecular diagnostics: Current achievements and future strategies.

Molecular diagnoses have become more widespread in many areas of laboratory medicine where qualitative or quantitative approaches are used to detect nucleic acids. The increasing number of assay methods and the targets for molecular diagnostics contribute to variability in the test results among clinical laboratories. Thus, reference materials (RMs) are required to enhance the comparability of results.

A diagnostic and epidemiologic investigation of acute febrile illness (AFI) in Kilombero, Tanzania.

In low-resource settings, empiric case management of febrile illness is routine as a result of limited access to laboratory diagnostics. The use of comprehensive fever syndromic surveillance, with enhanced clinical microbiology, advanced diagnostics and more robust epidemiologic investigation, could enable healthcare providers to offer a differential diagnosis of fever syndrome and more appropriate care and treatment.

The influence of different fever definitions on diagnostics and treatment after diagnosis of fever in chemotherapy-induced neutropenia in children with cancer.

There is no evidence-based definition of the temperature limit defining fever (TLDF) in children with neutropenia. Lowering the TLDF is known to increase the number of episodes of fever in neutropenia (FN). This study aimed to investigate the influence of a lower versus standard TLDF on diagnostics and therapy.

The Anatomy of a Nonfaradaic Electrochemical Biosensor.

Point-of-care (POC) testing has revolutionized diagnostic healthcare, bringing medical results directly and immediately to the patient. With faster diagnostics, more immediate clinical management decisions can be made. POC tests most often use a dipstick or swab format to detect the presence of a pathogen, disease, or other relevant biomarker. In these formats, the POC tests eliminate the need for complex lab equipment and trained personnel to collect, process, and analyze sample data for simple diagnostics...

Perspectives for applying the additional study methods for diagnostics optimization of postoperative hypertrophic scars of the head and neck.

Introduction: The issue of improving the quality of diagnosis, prevention and treatment of patients with pathological scarring of the head and neck is being actively developed throughout the world. The aim of the research is to improve diagnostics of hypertrophic scars of the head and neck through the establishment of structural features of scar-modified tissues using RGB-system and ultrasound examination.

Peculiarities of the early diagnostics of malignant nasopharyngal neoplasms.

The authors consider the risk factors and the specific clinical symptoms of the malignant nasopharyngal neoplasms as well as the methods for instrumental, laboratory, and pathomorphological diagnostics of this pathology. The full scale implementation of the recommendations for the timely detection of the tumours using the aforementioned diagnostic procedures and tests makes it possible to reduce to a minimum the interval between the establishment of the diagnosis and the onset of the relevant treatment at t...

Development and preliminary evaluation of a multiplexed amplification and next generation sequencing method for viral hemorrhagic fever diagnostics.

We describe the development and evaluation of a novel method for targeted amplification and Next Generation Sequencing (NGS)-based identification of viral hemorrhagic fever (VHF) agents and assess the feasibility of this approach in diagnostics.

Models for predicting the evolution of influenza to inform vaccine strain selection.

Influenza vaccine composition is reviewed before every flu season because influenza viruses constantly evolve through antigenic changes. To inform vaccine updates, laboratories that contribute to the World Health Organization Global Influenza Surveillance and Response System monitor the antigenic phenotypes of circulating viruses all year round. Vaccine strains are selected in anticipation of the upcoming influenza season to allow adequate time for production. A mismatch between vaccine strains and predomin...

Misleading by Omission: Rethinking the Obligation to Inform Research Subjects about Funding Sources.

Informed consent requirements for medical research have expanded over the past half-century. The Declaration of Helsinki now includes an explicit positive obligation to inform subjects about funding sources. This is problematic in a number of ways and seems to oblige researchers to disclose information irrelevant to most consent decisions. It is argued here that such a problematic obligation involves an "informational fallacy." The aim in the second part of the paper is to provide a better approach to makin...

Diagnostic potential and future directions of biomarkers in gingival crevicular fluid and saliva of periodontal diseases: Review of the current evidence.

The holy grail of biomarker research in periodontology is to develop a high impact diagnostics which have a significant impact on clinical decision-making, patient outcomes and healthcare providers. In the field of periodontal diagnostics, oral fluid-based biomarkers have been studied mainly in the gingival crevicular fluid (GCF) and saliva.

The pitfalls of laboratory diagnostics of Clostridium difficile infection.

The commentary summarises recently published findings on difficulties in Clostridium difficile infection (CDI) laboratory diagnostics and thus provides added value to a recently published article: "How to: Diagnose infection caused by Clostridium difficile." by van C. Gateau and colleagues.

INfORM: Inference of NetwOrk Response Modules.

Detecting and interpreting responsive modules from gene expression data by using network-based approaches is a common but laborious task. It often requires the application of several computational methods implemented in different software packages, forcing biologists to compile complex analytical pipelines. Here we introduce INfORM (Inference of NetwOrk Response Modules), an R shiny application that enables non-expert users to detect, evaluate, and select gene modules with high statistical and biological si...

Diagnostics for yaws eradication: insights from direct next generation sequencing of cutaneous strains of Treponema pallidum.

Yaws-like chronic ulcers can be caused by Treponema pallidum subsp. pertenue, Haemophilus ducreyi, or other still-undefined bacteria. To permit accurate evaluation of yaws elimination efforts programmatic use of molecular diagnostics is required. The accuracy and sensitivity of current tools remains unclear because our understanding of T. pallidum diversity is limited by the low number of sequenced genomes.

Diagnostics for Lassa Fever: Detecting Host Antibody Responses.

There are two types of viral diagnostics: (1) those that detect components of the pathogen (like viral RNA or proteins) and (2) those that detect host molecules that rise or fall as a consequence of pathogen infection (like anti-viral antibodies or virus-induced inflammatory cytokines). Quantitative PCR to detect Lassa RNA, and clinical chemistry to detect high liver enzymes (AST/ALT) are commonly used to diagnose Lassa fever. Here, we discuss the various types of diagnostics for Lassa fever and the urgent ...

Laboratory evaluation of immunochromatographic rapid diagnostic tests for cholera in Haiti.

Rapid diagnostic tests (RDT) for cholera are promising tools for detecting cholera in areas with limited laboratory infrastructure. However, evidence on the characteristics of the many available RDTs is scarce, and their use has been limited by suboptimal performance. We evaluated the performance characteristics of three cholera RDTs from Span Diagnostics, Artron Laboratories, and Standard Diagnostics in a regional laboratory in Haiti.

Using Contact Patterns to Inform HIV Interventions in Persons Who Inject Drugs in Northern Vietnam.

Population mixing patterns can greatly inform allocation of HIV prevention interventions such as treatment as prevention (TasP) or preexposure prophyloaxis (PrEP). Characterizing contact patterns among subgroups can help identify the specific combinations of contact expected to result in the greatest number of new infections.

Biomedical analysis of formalin-fixed, paraffin-embedded tissue samples: The Holy Grail for molecular diagnostics.

More than a century ago in 1893, a revolutionary idea about fixing biological tissue specimens was introduced by Ferdinand Blum, a German physician. Since then, a plethora of fixation methods have been investigated and used. Formalin fixation with paraffin embedment became the most widely used types of fixation and preservation method, due to its proper architectural conservation of tissue structures and cellular shape. The huge collection of formalin-fixed, paraffin-embedded (FFPE) sample archives worldwid...

Towards lab-on-a-chip diagnostics for malaria elimination.

Malaria continues to be one of the most devastating diseases impacting global health. Although there have been significant reductions in global malaria incidence and mortality rates over the past 17 years, the disease remains endemic throughout the world, especially in low- and middle-income countries. The World Health Organization has put forth ambitious milestones moving toward a world free of malaria as part of the United Nations Millennium Goals. Mass screening and treatment of symptomatic and asymptoma...


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