PubMed Journals Articles About "Integrated Genomics" RSS

11:43 EDT 18th March 2019 | BioPortfolio

Integrated Genomics PubMed articles on BioPortfolio. Our PubMed references draw on over 21 million records from the medical literature. Here you can see the latest Integrated Genomics articles that have been published worldwide.

More Information about "Integrated Genomics" on BioPortfolio

We have published hundreds of Integrated Genomics news stories on BioPortfolio along with dozens of Integrated Genomics Clinical Trials and PubMed Articles about Integrated Genomics for you to read. In addition to the medical data, news and clinical trials, BioPortfolio also has a large collection of Integrated Genomics Companies in our database. You can also find out about relevant Integrated Genomics Drugs and Medications on this site too.

Showing "Integrated Genomics" PubMed Articles 1–25 of 3,300+

Genomics of drug sensitivity in bladder cancer: an integrated resource for pharmacogenomic analysis in bladder cancer.

Bladder cancer has numerous genomic features that are potentially actionable by targeted agents. Nevertheless, both pre-clinical and clinical research using molecular targeted agents have been very limited in bladder cancer.

FungiDB: An Integrated Bioinformatic Resource for Fungi and Oomycetes.

FungiDB ( is a free online resource for data mining and functional genomics analysis for fungal and oomycete species. FungiDB is part of the Eukaryotic Pathogen Genomics Database Resource (EuPathDB, platform that integrates genomic, transcriptomic, proteomic, and phenotypic datasets, and other types of data for pathogenic and nonpathogenic, free-living and parasitic organisms. FungiDB is one of the largest EuPathDB databases containing nearly 100 genomes obtained from GenBank, Gen...

A Short Report on the Markov Property of DNA Sequences on 200-bp Genomic Units of Roadmap Genomics ChromHMM Annotations: A Computational Perspective.

The non-coding DNA in eukaryotic genomes encodes a language that programs chromatin accessibility, transcription factor binding, and various other activities. The objective of this study was to determine the effect of the primary DNA sequence on the epigenomic landscape across a 200-base pair of genomic units by integrating 127 publicly available ChromHMM BED files from the Roadmap Genomics project. Nucleotide frequency profiles of 127 chromatin annotations stratified by chromatin variability were analyzed ...

Infrastructures of systems biology that facilitate functional genomic study in rice.

Rice (Oryza sativa L.) is both a major staple food for the worldwide population and a model crop plant for studying the mode of action of agronomically valuable traits, providing information that can be applied to other crop plants. Due to the development of high-throughput technologies such as next generation sequencing and mass spectrometry, a huge mass of multi-omics data in rice has been accumulated. Through the integration of those data, systems biology in rice is becoming more advanced.To facilitate s...

Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis.

The growing availability of genomic information to the public may spur discussion about genetics and genomics on social media. Sites, including Twitter, provide a unique space for the public to access and discuss health information. The objective of this study was to better understand how social media users are sharing information about genetics and genomics in health and healthcare and what information is most commonly discussed among Twitter users.

Rice Genomics: Over the Past Two Decades and Into the Future.

Domestic rice (Oryza sativa L.) is one of the most important cereal crops, feeding a large number of worldwide populations. Along with various high-throughput genome sequencing projects, rice genomics has been making great headway toward direct field applications of basic research advances in understanding the molecular mechanisms of agronomical traits and utilizing diverse germplasm resources. Here, we briefly review its achievements over the past two decades and present the potential for its bright future...

An International Summit in Human Genetics and Genomics: Empowering clinical practice and research in developing countries.

To help fill the knowledge gap in human genetics and genomics, an International Summit (IS) in Human Genetics and Genomics was conceived and organized by the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) as a 5-year initiative, from 2016 to 2020. In its first 3 years, 71 professionals from 34 countries received training.

Striving for Precision: Enhancing Genetic Competency in Primary Care Nurse Practitioner Students.

Research in genetics and genomics has led to the development of precision medicine, with health care increasingly individually based on one's genetic makeup. Implementation of genetics and genomics in primary care has been challenging given the rapid development of new advances. Clinicians report difficulties incorporating genetics and genomics in practice, citing insufficient knowledge, training, confidence, and resources for genetic diagnoses, testing, and result reporting.

The Development of Human Genetics at the National Research Centre, Cairo, Egypt: A Story of 50 Years.

This article describes my experiences over more than 50 years in initiating and maintaining research on human genetics and genomics at the National Research Centre in Cairo, Egypt, from its beginnings in a small unit of human genetics to the creation of the Center of Excellence for Human Genetics. This was also the subject of a lecture I gave at the 10th Conference of the African Society of Human Genetics, held in Cairo in November 2017, after which Professor Michèle Ramsay, president of the society, sugge...

Exploring and exploiting pan-genomics for crop improvement.

Genetic variation ranging from single nucleotide polymorphisms (SNPs) to large structural variants (SVs) can cause variation of gene content among individuals within the same species. There is an increasing appreciation that a single reference genome is insufficient to capture the full landscape of genetic diversity of a species. Pan-genome analysis offers a platform to evaluate genetic diversity of a species via investigation of its entire genome repertoire. Although a recent wave of pan-genomic studies ha...

Genetics and genomics in Peru: Clinical and research perspective.

Peruvians currently preserve in their DNA the history of 2.5 million years of human evolution and 150,000 years of migration from Africa to Peru or the Americas. The development of Genetics and Genomics in the clinical and academic field is shown in this review.

Integrated wastewater management: The future of water reuse in large metropolitan areas.

The radish genome database (RadishGD): an integrated information resource for radish genomics.

Radish (Raphanus sativus L.) is an important root vegetable crop in the family Brassicaceae, which provides diverse nutrients for human health and is closely related to the Brassica crop species. Recently, we sequenced and assembled the radish genome into nine chromosome pseudomolecules. In addition, we developed diverse genomic resources, including genetic maps, molecular markers, transcriptome, genome-wide methylation and variome data. In this study, we describe the radish genome database (RadishGD), incl...

Learning from integrated management approaches to implement the Nexus.

In the 1990s, the emergence of Integrated Management Approaches to water, land and waste established a widely accepted understanding on integration of environmental systems. Nexus Approaches try to often build on these. This paper assesses i) the intended goals and features of three Integrated Management Approaches (Integrated Natural Resources Management - INRM, Integrated Water Resources Management - IWRM and Integrated Solid Waste Management - ISWM) and two Nexus Approaches (Water-Energy-Food (WEF) Nexus...

Opinion: Strategy of Semi-Automatically Annotating Full Text Corpus of Genomics & Informatics.

There is a community need for an annotated corpus consisting of the full texts of biomedical journal articles. In response to community needs, a prototype version of full text corpus of Genomics & Informatics, called GNI version 1.0 has been recently published, with 499 annotated full text articles available as a corpus resource. However, GNI needs to be updated, as the texts were shallow-parsed, and annotated with several existing parsers. I list issues associated with upgrading annotations, and give o...

Challenges and opportunities for effective delivery of clinical genetic services in the U.S. healthcare system.

Demand for clinical genetics and genomics services is increasing. As discussed in this study, the clinical genetics and genomics workforce is small. How to meet the demand with a limited workforce requires innovation.

ppsPCP: A Plant Presence/absence Variants Scanner and Pan-genome Construction Pipeline.

Since the idea of pan-genomics emerged several tools and pipelines have been introduced for prokaryotic pan-genomics. However, not a single comprehensive pipeline has been reported which could overcome multiple challenges associated with eukaryotic pan-genomics. To aid the eukaryotic pan-genomic studies, here we present ppsPCP pipeline which is designed for eukaryotes especially for plants. It is capable of scanning presence/absence variants (PAVs) and constructing a fully annotated pan-genome. We believe w...

Astrocyte-induced positive integrated information in neuron-astrocyte ensembles.

Integrated information is a quantitative measure from information theory of how tightly all parts of a system are interconnected in terms of information exchange. In this study we show that astrocytes, playing an important role in regulation of information transmission between neurons, may contribute to a generation of positive integrated information in neuronal ensembles. Analytically and numerically we show that the presence of astrocytic regulation of neurotransmission may be essential for this informati...

Characterization of HPV integration, viral gene expression and E6E7 alternative transcripts by RNA-Seq: A descriptive study in invasive cervical cancer.

Scarce data are available on the expression of Papillomavirus genome and the frequency of alternatively spliced E6/E7 mRNAs in invasive cervical cancer. We carried out a comprehensive characterization of HPV expression by RNA-Seq analysis in 22 invasive cervical cancer with HPV16 or HPV18, characterizing the presence of integrated/episomal viral DNA, the integration sites in human genome and the proportion of alternative splicing products of E6 and E7 genes. The expression patterns suggested the presence of...

RNA-seq data of the L. shoot system.

L. or the physic nut is a monoecious shrub belonging to the family. The plant is an ideal feedstock for biodiesel production; oil-rich seed (37-42%), has a broad range of growth habitat such as arid, semi-arid and tropical and a relatively feasible process for conversion of crude oil into biodiesel. The major constraint affecting the success of large-scale plantation is seed yield inconsistency. Numerous research projects conducted on with integrated genetic, genomic and transcriptomic approaches have be...

Hybrid assembly of ultra-long nanopore reads augmented with 10×-genomics contigs: Demonstrated with a human genome.

The 3rd generation of sequencing (3GS) technologies generate ultra-long reads (up to 1 Mb), which makes it possible to eliminate gaps and effectively resolve repeats in genome assembly. However, the 3GS technologies suffer from the high base-level error rates (15%-40%) and high sequencing costs. To address these issues, the hybrid assembly strategy, which utilizes both 3GS reads and inexpensive NGS (next generation sequencing) short reads, was invented. Here, we use 10×-Genomics® technology, which integ...

Genomic Interventions in Medicine.

Lately, the term "genomics" has become ubiquitous in many scientific articles. It is a rapidly growing aspect of the biomedical sciences that studies the genome. The human genome contains a torrent of information that gives clues about human origin, evolution, biological function, and diseases. In a bid to demystify the workings of the genome, the Human Genome Project (HGP) was initiated in 1990, with the chief goal of sequencing the approximately 3 billion nucleotide base pairs of the human DNA. Since it...

Actions required to implement integrated care for older people in the community using the World Health Organization's ICOPE approach: A global Delphi consensus study.

Integrated care is recognised as an important enabler to healthy ageing, yet few countries have managed to sustainably deliver integrated care for older people. We aimed to gather global consensus on the key actions required to realign health and long-term systems and integrate services to implement the World Health Organization (WHO) Integrated Care for Older People (ICOPE) approach.

Crunching The Numbers On Integrated Care.

Data from the California Regional Health Care Cost and Quality Atlas make the case for integrated delivery systems.

Optimal Integration of Behavioral Medicine into Clinical Genetics and Genomics.

Clinical genetics and genomics will exert their greatest population impact by leveraging the rich knowledge of human behavior that is central to the discipline of behavioral medicine. We contend that more concerted efforts are needed to integrate these fields synergistically, and accordingly, we consider barriers and potential actions to hasten such integration.

Quick Search