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PubMed Journals Articles About "Marrow Adipose Tissue Adolescent Girls With Obesity" RSS

21:57 EST 28th February 2020 | BioPortfolio

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Showing "Marrow Adipose Tissue Adolescent Girls with Obesity" PubMed Articles 1–25 of 13,000+

Marrow Adipose Tissue in Adolescent Girls with Obesity.

Marrow adipose tissue (MAT) is increasingly recognized as an active and dynamic endocrine organ that responds to changes in nutrition and environmental milieu. Compared to normal weight controls, adolescent girls with anorexia nervosa have higher MAT content, which is associated with impaired skeletal integrity, but data are limited regarding MAT content in adolescents with obesity and how this interacts with bone endpoints.


Obesity and osteoporosis-connections between adipose tissue and bone.

The adipose and osseous tissue, although both derived from the connective tissues, perform different functions. In the common opinion, obesity might be a protective factor against bone loss and osteoporosis. The adipose tissue is a recognized major endocrine organ, producing a number of active biological substances, which affect the bone mass. Adipocyte and osteoblast are derived from the same mesenchymal stem cells. Therefore abnormal secretion of adipocytokines may play an important role not only in patho...

Measures of Adipose Tissue Redistribution and Atherosclerotic Coronary Plaque in HIV.

People with HIV (PWH) who are well treated on antiretroviral therapy remain at increased risk for body composition changes, including increased visceral adipose tissue (VAT) and reduced subcutaneous adipose tissue (SAT), as well as increased cardiovascular disease (CVD). The relationship between adipose compartments and coronary disease is not well understood among PWH.


The effects of dietary fatty acids on bone, hematopoietic marrow and marrow adipose tissue in a murine model of senile osteoporosis.

Marrow adipose tissue (MAT) expansion and associated lipotoxicity are important drivers of age-related bone loss and hematopoietic bone marrow (HBM) atrophy. Fish oil and borage oil (rich in ω3 fatty acids) can partially prevent aged-related bone loss in SAMP8 mice. However, whether preservation of bone mass in this progeria model is associated with MAT volumes remains unknown. MAT volume fraction (MAT%) showed a negative association with hematopoietic bone marrow (HBM%;r=-0.836,

Transitions to adulthood and the changing body mass index of adolescent girls in Zambia.

Adolescent girls in low- and middle-income countries often experience several important life transitions, including school-leaving, marriage, and childbearing. Understanding how these transitions are associated with changes in the nutritional status of adolescent girls and young women (AGYW) is crucial for programs that aim to improve nutritional outcomes among youth and promote healthy transitions to adulthood. We investigated the associations between adolescent transitions and body mass index (BMI) among ...

A Novel PET Probe for Brown Adipose Tissue Imaging in Rodents.

Brown adipose tissue (BAT) has emerged as a promising target to counteract obesity and its associated metabolic disorders. However, the detection of this tissue remains one of the major roadblocks.

Status and factors of menstrual knowledge, attitudes, behaviors and their correlation with psychological stress in adolescent girls.

Adolescent girls perceive menstruation as a negative experience, which can affect adolescents' physical and mental health. The aims of this study were to describe the menstrual knowledge, attitudes, and behaviors of adolescent girls in China and to examine their association with psychological stress.

Adipose tissue: immune function and alterations caused by obesity.

The adipose tissue, which is currently viewed as an organ with neuroimmunoendocrine functions, participates in the homeostasis of the human organism. It has great plasticity and functional variability based on the intake of nutrients or to the increase or decrease of its tissue volume, which modifies both the function and the number of the cells that form it or reach it. The elements that are released abnormally by these cells, among other cytokines and adipokines, cause both local and systemic inflammation...

New Insight Into Apolipoprotein A5 and the Modulation of Human Adipose-Derived Mesenchymal Stem Cells Adipogenesis.

The hallmark of obesity is excessive accumulation of triglyceride (TG) in adipose tissue. Apolipoprotein A5 (ApoA5) has been shown to influence the prevalence and pathology of obesity. However, the underlying mechanisms remains to be unclarified.

The Combination of Whey Protein and Dietary Fiber Does Not Alter Low-Grade Inflammation or Adipose Tissue Gene Expression in Adults with Abdominal Obesity.

Abdominal obesity is characterized by low-grade inflammation and plays a central role in the development of type 2 diabetes and cardiovascular diseases. Dietary factors can influence low-grade inflammation and affect adipose tissue function.

Human Adipose Tissue Derivatives as a Potent Native Biomaterial for Tissue Regenerative Therapies.

Human adipose tissue is a great source of translatable biomaterials owing to its ease of availability and simple processing. Reusing discardable adipose tissue for tissue regeneration helps in mimicking the exact native microenvironment of tissue. Over the past 10 years, extraction, processing, tuning and fabrication of adipose tissue have grabbed the attention owing to their native therapeutic and regenerative potential. The present work gives the overview of next generation biomaterials derived from huma...

Contraceptive Use in Adolescent Girls and Adult Women in Low- and Middle-Income Countries.

Preventing unwanted pregnancy through adequate use of contraceptives among adolescent girls is essential for improving maternal and child health and social well-being.

Obesity and Androgens in Women.

Androgen excess is often associated with obesity states, at any age of life, because of changes in the pattern of secretion or metabolism of androgens and in their actions at the level of target tissues, particularly the adipose tissue. Androgen excess plays an important role in favouring the expansion of visceral fat, which characterize so-called visceral obesity. Moreover, there is evidence that the combination of androgen excess and obesity may favour the development of metabolic disorders, such as the m...

Adipose vascular endothelial growth factor B is a major regulator of energy metabolism.

Excessive fat accumulation causes obesity and many diseases. Previous study demonstrates VEGFB universal knockout induces obese phenotypes including expansion of white adipose tissue, whitening of brown adipose tissue, increase of fat accumulation and reduction in energy consumption. However, roles of VEGFB in adipose tissues are not clear. In this study, we have generated a mouse model with adipose-specific VEGFB repression using CRISPR/dCas9 system (VegfbAdipoDown) and investigated the roles of VEGFB in a...

SOCS2 modulates adipose tissue inflammation and expansion in mice.

Obesity is usually triggered by a nutrient overload that favors adipocyte hypertrophy and increases the number of pro-inflammatory cells and mediators into adipose tissue. These mediators may be regulated by suppressors of cytokine signaling (SOCS), such as SOCS2, which is involved in the regulation of the inflammatory response of many diseases, but its role in obesity is not yet known. We aimed to investigate the role of SOCS2 in metabolic and inflammatory dysfunction induced by a high-refined carbohydrate...

Adipose Tissue B Cells Come of Age: The AABs of Fat Inflammation.

For nearly a decade, B cells residing locally within the adipose tissue have been linked to the control of metabolic homeostasis. In this issue, Camell et al. (2019) report an expansion of a unique age-associated B cell population in the visceral adipose tissue that regulates insulin resistance and adipose dysfunction during aging.

MRI Assessment of Bone Marrow Composition in Osteoporosis.

To provide an overview on recent technical development for quantifying marrow composition using magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques, as well as a summary on recent findings of interrelationship between marrow adipose tissue (MAT) and skeletal health in the context of osteoporosis.

Sex hormones, gonad size and metabolic profile in adolescent girls born small-for-gestational age with catch-up growth.

To characterize and compare sex hormone concentrations, and uterine and ovarian volumes in adolescent girls born small for gestational age (SGA) who had experienced catch-up growth and girls born at a size appropriate for gestational age (AGA), and to investigate the association between these parameters and glucose metabolism, perinatal factors and early growth.

The role of autophagy in brown and beige adipose tissue plasticity.

Since the rediscovery of active brown and beige adipose tissues in humans a decade ago, great efforts have been made to identify the mechanisms underlying the activation and inactivation of these tissues, with the hope of designing potential strategies to fight against obesity and associated metabolic disorders such as type 2 diabetes. Active brown/beige fat increases the energy expenditure and is associated with reduced hyperglycemia and hyperlipidemia, whereas its atrophy and inactivation have been associ...

Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway.

The T-box gene Tbx15 is abundantly expressed in adipose tissues, especially subcutaneous and brown fat. Although its expression is correlated with obesity, its precise biological role in adipose tissue is poorly understood in vivo. Here we investigated the function of Tbx15 in brown adipose thermogenesis and white adipose browning in vivo.

Changes in adipose tissue lipolysis gene expression and insulin sensitivity after weight loss.

Insulin resistance is a major pathophysiological link between obesity and its metabolic complications. Weight loss (WL) is an effective tool to prevent obesity-related diseases, however, the mechanisms of an improvement in insulin sensitivity (IS) after weight-reducing interventions are not completely understood. The aim of the present study was to analyze the relationships between IS and adipose tissue (AT) expression of the genes involved in the regulation of lipolysis in obese subjects after WL.

Prospective Prediction of First-Onset of Non-Suicidal Self-Injury in Adolescent Girls.

Adolescent non-suicidal self-injury (NSSI) is a significant risk factor for suicidal behavior and an important clinical marker of psychopathology. NSSI is especially common in adolescent girls. A number of psychosocial correlates of adolescent NSSI have been identified, including problems characterized by disinhibition and negative affectivity. However, it is unknown if these characteristics prospectively predict first-onset NSSI, limiting our understanding of its etiology and prevention. The current study ...

Abdominal visceral and subcutaneous adipose tissues in association with cardiometabolic risk in children and adolescents: the China Child and Adolescent Cardiovascular Health (CCACH) study.

To investigate the association of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) with cardiometabolic risk factors in children and adolescents.

Relation of adipose tissue insulin resistance to prediabetes.

The degree of adipose tissue insulin resistance increases in obesity, prediabetes and type 2 diabetes, but whether it associates with prediabetes is unclear.

Obesity and Insulin Resistance Are Inversely Associated with Serum and Adipose Tissue Carotenoid Concentrations in Adults.

Low tissue concentrations of carotenoids have been suggested to contribute to insulin resistance in obesity.


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