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18:06 EST 23rd February 2020 | BioPortfolio

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Showing "Pickering Laboratories Incorporated" PubMed Articles 1–25 of 506

Chitosan hydrochloride/carboxymethyl starch complex nanogels stabilized Pickering emulsions for oral delivery of β-carotene: Protection effect and in vitro digestion study.

β-Carotene was encapsulated in the Pickering emulsions stabilized by chitosan hydrochloride - carboxymethyl starch (CHC-CMS) nanogels. During ultraviolet radiation and storage, the retention of β-carotene in Pickering emulsions was higher than that of other formulations, such as Tween 80 stabilized emulsions (TEs) and bulk oil. The Pickering emulsions were found to be stable during thermal treatment. Meanwhile, lipid oxidation was delayed in Pickering emulsions compared to TEs and bulk oil. The vitro dige...


Preparation and Characterization of pH-Responsive Pickering Emulsion Stabilized by Grafted Carboxymethyl Starch Nanoparticles.

Copolymer nanoparticles with pH-responsive properties were prepared by grafting different amounts of 2-(dimethylamine) ethyl methacrylate (DMAEMA) on carboxymethyl maize starch (CMS). The formation of CMS-g- DMAEMA was verified by different techniques and was then used for stabilization of Pickering emulsion at different pH values. The CMS-g-DMAEMA nanoparticles showed pH-responsive properties in Pickering emulsion and the pH-responsivity increased as the amount of DMAEMA increased in the CMS-g-DMAEMA copol...

Novel gel-like Pickering emulsions stabilized solely by hydrophobic starch nanocrystals.

The development of gel-like Pickering emulsions stabilized by edible particles has attracted significant interest in the food colloid field. This work reported that starch nanocrystals (SNCs), modified by octenyl succinic anhydride (OSA), could introduced as a natural stabilizer for gel-like Pickering emulsions. The formation, microstructure and stability of Pickering emulsions were characterized by visual observations and optical microscopy. The results indicated that surface modification improved the hydr...


Recent advances of characterization techniques for the formation, physical properties and stability of Pickering emulsion.

Recently, there have been increasing demand for the application of Pickering emulsions in various industries due to its combined advantage in terms of cost, quality and sustainability. This review aims to provide a complete overview of the available methodology for the physical characterization of emulsions that are stabilized by solid particles (known as Pickering emulsion). Current approaches and techniques for the analysis of the formation and properties of the Pickering emulsion were outlined along with...

One-step processing of highly viscous multiple Pickering emulsions.

Solid-stabilized Pickering emulsions have attracted a lot of attention recently due to their surfactant-free character, and exceptional stability. At the moment, how the viscosities of the liquid phases impact the processing of Pickering emulsions remain to be clearly understood - it is however an important parameter to consider when developing chemical engineering processes employing these multiphase liquids. Our first assumption was that the amount of emulsified dispersed phase would drastically decrease ...

Polymeric hollow microcapsules (PHM) via cellulose nanocrystal stabilized Pickering emulsion polymerization.

A practical and sustainable method to prepare polymeric hollow microcapsules (PHMs) using cellulose nanocrystal (CNC) stabilized Pickering emulsion polymerization was developed. Pristine CNCs hydrolyzed from wood pulp are hydrophilic and could be employed as emulsifiers to prepare oil-in-water (O/W) Pickering emulsions. The O/W Pickering emulsions were used as templates for the Pickering emulsion polymerization of hydrophobic monomers inside the emulsion droplets. The crosslinked hydrophobic polymers phase ...

Enhancing trans-resveratrol topical delivery and photostability through entrapment in chitosan/gum Arabic Pickering emulsions.

The surfactant-free nature and higher stability of Pickering emulsions make them preferable solutions over conventional emulsions for skin applications. In this work, Pickering emulsions stabilized by chitosan/gum Arabic (CH/GA) nanoparticles were tested as vehicles for trans-resveratrol topical delivery. Skin absorption was examined ex vivo using Franz diffusion cells and porcine skin. Pickering emulsions allowed higher cutaneous retention and lower permeation of resveratrol, in comparison with a control s...

Inverse Pickering Emulsion Stabilized by Binary Particles with Contrasting Characteristics and Functionality for Interfacial Bio-catalysis.

Water-in-oil (w/o) Pickering emulsions have received considerable attention in biphasic enzymatic catalysis for their advantages of good stability, large interfacial area, and ease of product separation. However, enzymes are commonly encapsulated in the interior of aqueous droplets, which inevitably increases the diffusional resistance to catalysis. Alternatively, enzymes are immobilized or trapped into Pickering stabilizers. Often, however, these approaches suffer from leaching and a decrease of enzyme act...

Fabrication, Physicochemical Stability and Microstructure of Coenzyme Q10 Pickering Emulsions Stabilized by Resveratrol Loaded Composite Nanoparticles.

The aim of this study was to develop a novel system for the co-delivery of resveratrol and coenzyme Q10 (CoQ10). It was achieved with a combination of resveratrol loaded composite nanoparticles and CoQ10 loaded Pickering emulsions. Different levels of resveratrol (0.05% - 0.30%, w/v) were entrapped into composite nanoparticles by the method of emulsification-evaporation. The size of composite nanoparticles was around 300-600 nm and the maximum loading capacity of resveratrol was up to 13.88% (w/w). Hydrogen...

Protein-based Pickering High Internal Phase Emulsions as Nutraceutical Vehicles of and the Template for Advanced Materials: A Perspective Paper.

Pickering high internal phase emulsions (HIPEs) are normally highly concentrated emulsions stabilized by colloidal particles with a minimum internal phase volume fraction of 0.74. They have received considerable attentions in many fields, including pharmaceuticals, tissue engineering, foods, as well as personal care products. The aim of this perspective is to update the current knowledge on the field of protein-based Pickering HIPEs, emphasizing those aspects that need to be explored and clarified. Research...

Interfacial characteristics of block copolymer micelles stabilized Pickering emulsion by confocal laser scanning microscopy.

Novel Pickering emulsions stabilized by self-assembled nano-objects of amphiphilic copolymers are attractive in many applications. However, it is not clear to what extent those nano-objects could stay at the oil/water interface. Owing to the twisted intramolecular charge transfer state (TICT) property of Nile red, the distinguishable fluorescent characteristics of Nile red dissolved in n-dodecane and solubilized in copolymer micelles benefit the investigation of the oil/water interfacial nature of Pickering...

Combining in vitro digestion model with cell culture model: Assessment of encapsulation and delivery of curcumin in milled starch particle stabilized Pickering emulsions.

To investigate the encapsulation and oral delivery efficiency of milled starch particles stabilized Pickering emulsions for lipophilic bioactive compounds, in vitro digestion model coupled with Caco-2 cells models were used. Physicochemical and biological properties of curcumin encapsulated Pickering emulsions were analyzed regarding to emulsion structure, curcumin retention, in vitro digestion, in vitro anti-proliferate ability and cellular uptake. Milled starch particles stabilized Pickering emulsion syst...

Pickering emulsion gel stabilized by octenylsuccinate quinoa starch granule as lutein carrier: Role of the gel network.

Octenylsuccinate quinoa starch (OSQS) granule that stabilized Pickering emulsion gel with different gel networks by modulating the oil volume fraction (Φ) was developed as a carrier for lutein. Pickering emulsion gels stabilized by OSQS were achieved at Φ values ranging from 30% to 60%. Increasing Φ progressively increased the droplet size, storage modulus, and apparent viscosity, resulting in the formation of gel-like structure. Confocal laser scanning microscopy showed that OSQS formed a densely packed...

Highly surface-active chaperonin nano-barrels for oil-in-water Pickering emulsions and lipophilic compounds delivery.

Stabilization of Pickering emulsions via particles of biological origin exhibits a great potential to be widely applied in food, cosmetic or biomedicine formulation, due to their excellent biocompatibility, biodegradability as well as functional properties. This paper describes the successful development of bio-derived GroEL protein nano-barrel as a Pickering stabilizer, and its protection properties on β-carotene in dispersed oil phase, as a model of labile bioactive compounds. It is shown that GroEL nano...

Pickering emulsion process assisted construction of regenerated chitin reinforced poly (lactic acid) blends.

Regenerated chitin (RCh)/poly (lactic acid) (PLA) blends with enhanced properties were successfully prepared via the Pickering emulsion approach. An oil-in-water Pickering emulsion of PLA/dichloromethane (DCM) stabilized with RCh via an ultrasonic homogenizer was formed. A uniformly dispersed blends were obtained upon slow volatilization of DCM. The effects of RCh on physical/morphological, thermal, mechanical and rheology properties of the blends were studied. The introduction of RCh in PLA improved its cr...

Nano/Submicrometer milled red rice particle-stabilized Pickering emulsions and their antioxidative properties.

Nano/Submicrometer red rice particles were obtained through processing a type of red rice using media milling. The particle size of red rice was gradually reduced with the increasing of milling time. After milling time of 4 h, the particle size of milled red rice was reduced to around 692 nm. Microscopic observation and SEM analysis confirmed the presence of nano/submicrometer particles. The phytochemicals content of milled red rice was analyzed. The total anthocyanin content of red rice increased after mil...

Ultrasound pre-fractured casein and in-situ formation of high internal phase emulsions.

Traditional preparation of protein particles is usually complex and tedious, which is a major issue in the development of Pickering high internal phase emulsions (HIPEs). In this study, a facile and in-situ method for the preparation of food-grade Pickering HIPEs was developed using ultrasound pre-fractured casein flocs. The ultrasonic-treated casein protein and resulting Pickering HIPEs were characterised using particle size distribution, confocal laser scanning microscopy (CLSM), cryo-SEM, and rheological...

Water-insoluble dietary fibers from bamboo shoot used as plant food particles for the stabilization of O/W Pickering emulsion.

In this work, water-insoluble bamboo shoot dietary fiber (BSDF) was prepared, and used as plant food particle stabilizer for oil-in-water (O/W) Pickering emulsions. The obtained plant food particle had novel emulsification ability, the prepared emulsions were stable against coalescence for at least 4 weeks and also insensitive to pH, ionic strength and pasteurization conditions. The BSDF suspensions and BSDF-stabilized O/W emulsions both exhibited shear-thinning behaviors; moreover, both viscosity and modu...

Hemostasis critical values among Iranian clinical laboratories "National Survey of 157 Clinical Laboratories".

Immediate reporting of critical values or test results significantly outside the normal range has a growing role in the management of patients, especially in life-threatening conditions. Due to the lack of international consensus, diverse approaches are used for determination of thresholds, reporting, documentation, and follow-up. In this study, we assessed how Iranian laboratories manage critical values for hemostasis.

A microgel-Pickering emulsion route to colloidal molecules with temperature-tunable interaction sites.

A simple Pickering emulsion route has been developed for the assembly of temperature-responsive poly(N-isopropylacrylamide) (PNIPAM) microgel particles into colloidal molecules comprising a small number of discrete microgel interaction sites on a central oil emulsion droplet. Here, the surface activity of the microgels serves to drive their assembly through adsorption to growing polydimethylsiloxane (PDMS) emulsion oil droplets of high monodispersity, prepared in situ via ammonia-catalysed hydrolysis and co...

Proficiency test for rabies serology: A design complying with international standards for a reliable assessment of participating laboratories.

Domestic carnivores can introduce rabies into disease-free countries or areas if they are incubating the disease and transported during the pre-symptomatic period. For pets moved into the European Union, the European Commission decided to establish a system of community approval of laboratories willing to carry out the rabies serological controls to guarantee an effective control system. As the specific institute to coordinate the approval of the laboratories, designated by the European Commission in 2000, ...

Performance assessment of medical diagnostic laboratories: A network DEA approach.

The main purpose of this paper is to measure the efficiency and ranking of medical diagnostic laboratories by applying a network data envelopment analysis (NDEA).

Modulation of Physicochemical Characteristics of Pickering Emulsions: Utilization of Nanocellulose- and Nanochitin-coated Lipid Droplet Blends.

Mixed Pickering emulsions were prepared by blending anionic nanocellulose-stabilized lipid droplets with cationic nanochitin-stabilized lipid droplets. Changes in the surface potential, particle size, shear viscosity, and morphology of the mixed emulsions were characterized when the droplet mixing ratio was varied. Emulsion properties could be tailored by altering the pH and mixing ratio. Surface potential measurements suggested that the nanochitin-coated lipid droplets adsorbed to the surfaces of the nanoc...

A 20-Year Evaluation of LOINC in the United States' Largest Integrated Health System.

Clinical laboratories are obligated to implement Logical Observation Identifier Names and Codes (LOINC), an informatics standard used to uniquely identify laboratory tests. The historical progress of laboratories in achieving this goal is unknown.

Dynamically Reconfigurable, Multifunctional Emulsions with Controllable Structure and Movement.

Dynamically reconfigurable oil-in-water (o/w) Pickering emulsions are developed, wherein the assembly of particles (i.e., platinum-on-carbon and iron-on-carbon particles) can be actively controlled by adjusting interfacial tensions. A balanced adsorption of particles and surfactants at the o/w interface allows for the creation of inhomogeneity of the particle distribution on the emulsion surface. Complex Pickering emulsions with highly controllable and reconfigurable morphologies are produced in a single st...


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