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21:55 EDT 21st March 2019 | BioPortfolio

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Showing "Progress three dimensional printing with growth factors" PubMed Articles 1–25 of 29,000+

Progress in three-dimensional printing with growth factors.

Incorporation of growth factors in biomedical constructs can encourage cellular activities necessary for tissue regeneration within an implant system. Three-dimensional printing offers a capacity for spatial dictation and dosage control of incorporated growth factors which promises to minimize complications from the supraphysiologic doses and burst release involved in current growth factor delivery systems. Successful implementation of three-dimensional printing with growth factors requires preservation of ...

Three Dimensional Printed Bone Implants in the Clinic.

Implants are being continuously developed to achieve personalized therapy. With the advent of 3-dimensional (3D) printing, it is becoming possible to produce customized precisely fitting implants that can be derived from 3D images fed into 3D printers. In addition, it is possible to combine various materials, such as ceramics, to render these constructs osteoconductive or growth factors to make them osteoinductive. Constructs can be seeded with cells to engineer bone tissue. Alternatively, it is possible to...

Should You Buy a Three-Dimensional Printer? A Study of an Orbital Fracture.

The use of three-dimensional (3D) printing has been growing significantly in medicine for the past 10 years, especially in maxillofacial surgery. A lot a different softwares and printers are available on the market, and it can be difficult to choose which one fits best one's needs. In the authors' institution, the authors regularly print orbits to prepare the reconstruction. The authors then compared the 3D printing of an orbital fracture between a professional and nonprofessional software and between a bot...

3D printing for heart valve disease: a systematic review.

Current developments showed a fast-increasing implementation and use of three-dimensional (3D) printing in medical applications. Our aim was to review the literature regarding the application of 3D printing to cardiac valve disease.

Three-Dimensional Printing in Urology: History, Current Applications, and Future Directions.

To review the history, current applications, limitations, and future directions of three-dimensional (3D) printing within the field of urology. 3D printing is an additive manufacturing process in which a 3D model is created using a computer-generated image. This technology is applied by companies to create and test new drugs, design and manufacture instrument prototypes, and create patient-specific models of organs for surgical teaching and planning. A literature review was performed within the Web of Scien...

The beneficial application of preoperative 3D printing for surgical stabilization of rib fractures.

The beneficial application of three-dimensional (3D) printing for surgical stabilization of rib fractures (SSRF) has never been proposed in the literature before. The aim of this study was to verify patients' surgical outcomes when utilizing preoperative three-dimensional printing for SSRF.

Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): guidelines for medical 3D printing and appropriateness for clinical scenarios.

Medical three-dimensional (3D) printing has expanded dramatically over the past three decades with growth in both facility adoption and the variety of medical applications. Consideration for each step required to create accurate 3D printed models from medical imaging data impacts patient care and management. In this paper, a writing group representing the Radiological Society of North America Special Interest Group on 3D Printing (SIG) provides recommendations that have been vetted and voted on by the SIG a...

Clinical Application of 3-Dimensional Printing Technology for Patients With Nasal Septal Deformities: A Multicenter Study.

Studies have shown the controllability and porosity of polycaprolactone as well as the use of 3-dimensional (3-D) printing for nasal reconstruction in animal models. The utility of polycaprolactone with 3-D technology in nasal cartilaginous framework reconstruction in humans remains unknown.

3D Printing and Heart Failure: The Present and the Future.

Advanced imaging modalities provide essential anatomic and spatial information in patients with complex heart disease. Two-dimensional imaging can be limited in the extent to which true 3-dimensional (3D) relationships are represented. The application of 3D printing technology has increased the creation of physical models that overcomes the limitations of a 2D screen. Many groups have reported the use of 3D printing for preprocedural planning in patients with different causes of heart failure. This paper re...

Three-dimensional printing PEEK implant: a novel choice for the reconstruction of chest wall defect.

The purpose of this study is to use three-dimensional printing (3DP) polyether-ether-ketone (PEEK) implants for skeletal reconstructions after wide excision of chest wall. 3DP PEEK implants were expected to provide a better physiological simulation than traditional ones due to a closer elastic modulus to cortical bone and similar biomechanical properties.

Three-dimensional virtual traveling navigation and three-dimensional printing models of a normal fetal heart using ultrasonography data.

Clinical applications of three-dimensional printing in otolaryngology-head and neck surgery: A systematic review.

Medical three-dimensional (3D) printing, the fabrication of handheld models from medical images, has the potential to become an integral part of otolaryngology-head and neck surgery (Oto-HNS) with broad impact across its subspecialties. We review the basic principles of this technology and provide a comprehensive summary of reported clinical applications in the field.

High-throughput scaffold-free microtissues through 3D printing.

Three-dimensional (3D) cell cultures and 3D bioprinting have recently gained attention based on their multiple advantages over two-dimensional (2D) cell cultures, which have less translational potential to recapitulate human physiology. 3D scaffold supports, cell aggregate systems and hydrogels have been shown to accurately mimic native tissues and support more relevant cell-cell interactions for studying effects of drugs and bioactive agents on cells in 3D. The development of cost-effective, high-throughpu...

Role and mechanisms of a three-dimensional bioprinted microtissue model in promoting proliferation and invasion of growth-hormone-secreting pituitary adenoma cells.

Growth-hormone-secreting pituitary adenoma (GHSPA) is a benign tumour with a high incidence and large economic burden, which greatly affects quality of life. The aetiological factors are yet to be clarified for GHSPA. Conventional two-dimensional (2D) monolayer culture of tumour cells cannot ideally reflect the growth status of tumours in the physiological environment, and insufficiencies of in vitro models have severely restricted the progress of cancer research. Three-dimensional (3D) bioprinting technolo...

3D Bioprinting:principles, fantasies and prospects.

Conventional three-dimensional (3D) printing techniques have been growing in importance in the field of reconstructive surgery. Three-dimensional bioprinting is the adaptation of 3D printing techniques to tissue engineering, through the use of a bio-ink containing living cells and biomaterials. We hereby describe the principles of bioprinting, its main current limitations, and the prospects of this technique. A PubMed/MEDLINE search was performed. A total of 40 publications were included. To date, most of t...

Operative planning in Thoracic Surgery: A pilot study comparing imaging techniques and 3D printing.

Careful preoperative planning in thoracic surgery is essential for positive outcomes especially in video assisted thoracic surgery (VATS) where palpation and 3-dimensional imaging is restricted. The objective of this study was to evaluate the ability of different imaging techniques such as Computerized Tomography (CT) scanning, maximal intensity projection (MIP) imaging, 3-dimensional (3D) reconstruction as well as 3D printing, to define the anatomy of the hilar structures prior to anatomical lung resection...

Preoperative Planning Using 3-Dimensional Printing for Complex Paraspinal Schwannoma Resection: 2-Dimensional Operative Video.

Schwannomas are benign peripheral nerve sheath tumors that are typically round, smooth, and straightforward to resect. Occasionally they are more complicated to resect because of their size, location, degree of bony erosion, and vascular or neural compression. These complex lesions frequently require multidisciplinary surgical teams in order to decrease surgical morbidity. Historically, surgical planning consisted of imaging review and verbal communication among team members. 3-dimensional (3D) printing off...

Highly conductive, mechanically strong graphene monolith assembled by three-dimensional printing of large graphene oxide.

The manufacturing of three-dimensional (3D) graphene monolith with high mechanical and electrical performance has become an urgent issue in view of their potential applications in energy and electronics fields. Due to the structure rigidity and poor liquid-phase processing capability of graphene sheets, it is challenging to fabricate 3D graphene monolith with high mechanical performance, including strength, toughness and resiliency. Graphene oxide (GO) shows an improved dispersibility and reduction-restorab...

The 2D to 3D growth transition in the moss Physcomitrella patens.

The colonization of land by plants coincided with and was most likely facilitated by the evolution of 3-dimensional (3D) growth. 3D growth is a pivotal feature of all land plants, but most develop in a way that precludes genetic investigation. In the moss Physcomitrella patens, 3D growth (gametophores) is preceded by an extended 2-dimensional (2D) growth phase (protonemata) that can be propagated indefinitely. Studies using P. patens have thus elucidated some of the molecular mechanisms underlying 3D growth...

Using Three-Dimensional Printing to Enhance Cross-Sectional Anatomy Instruction.

The increased use of external interventions to diagnose and treat podiatric medical pathologies has warranted a greater understanding of the lower extremity in the transverse plane. Films, prosections, and plastinated cross sections have long been used alongside traditional instruction to assist students in anatomical studies. These methods, however, often fail to provide the tactile component of anatomical dissection and may obscure or exclude the requisite structures for identification by medical students...

Combinatorial Peptide Array Synthesis Based on Microfluidic Impact Printing.

In this paper, a novel inkjet printing technique, micro impact printing (MI printing), is applied for the first time to combinatorial peptide array synthesis on amine functionalized micro disc arrays through standard Fmoc chemistry. MI printing shows great advantages in combinatorial peptide array synthesis compared with other printing techniques, including 1) a disposable cartridge; 2) a small spot size (80 μm) increases array density; 3) minimal loading volume (0.6 μL) and dead volume (

Applications of 3D printing on craniofacial bone repair: A systematic review.

Three-dimensional (3D) bioprinting, a method derived from additive manufacturing technology, is a recent and ongoing trend for the construction of 3D volumetric structures. The purpose of this systematic review is to summarize evidence from existing human and animal studies assessing the application of 3D printing on bone repair and regeneration in the craniofacial region.

Compatibility of 3D printing materials and printing techniques with PAGAT gel dosimetry.

Polymer gel (PG) dosimetry enables three dimensional (3D) measurement of complex dose distributions. However, PGs are strongly reactive with oxygen and other contaminations, limiting their applicability by the need to use specific container materials. We investigate different 3D printing materials and printing techniques for their compatibility with PG. Suitable 3D printing materials may provide the possibility to perform PG dosimetry in complex-shaped phantoms. 3D printed and PG-filled test vials were irra...

Fabrication of a lightweight Al alloy mirror through 3D printing and replication methods.

In order to realize rapid fabrication of a lightweight mirror, an AlSi10Mg alloy mirror was made through 3D printing and replication methods. The mechanical, thermal, and physical properties, the surface accuracy, and the dimensional stability were investigated. Through a selective laser melting method, an Al alloy mirror was printed and exhibited a low areal density of 28.4  kg/m. Through replication, the mirror surface accuracy was improved to 0.033λ (root mean square, λ=632.8  nm); surface roug...

Use of Three-Dimensional Printing Models for Veterinary Medical Education: Impact on Learning How to Identify Canine Vertebral Fractures.

Vertebral fractures and luxations are common causes of neurological emergencies in small-animal patients. The objective of this study was to evaluate the impact of three-dimensional printing (3Dp) models on how veterinary students understand and learn to identify canine spinal fractures and to compare 3Dp models to computed tomography (CT) images and three-dimensional CT (3D-CT) reconstructions. Three spinal fracture models were generated by 3Dp. Sixty first-year veterinary students were randomized into thr...

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